LeishMANIAdb
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Surface antigen-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Surface antigen-like protein
Gene product:
surface antigen-like protein
Species:
Leishmania major
UniProt:
Q9XZY0_LEIMA
TriTrypDb:
LmjF.04.0200 , LMJLV39_040006800 , LMJSD75_040006900
Length:
182

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 5, no: 0
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9XZY0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9XZY0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 4 8 PF00082 0.531
DEG_SPOP_SBC_1 66 70 PF00917 0.568
DOC_MAPK_MEF2A_6 162 170 PF00069 0.579
DOC_USP7_MATH_1 145 149 PF00917 0.466
DOC_USP7_MATH_1 153 157 PF00917 0.459
DOC_USP7_MATH_1 20 24 PF00917 0.503
DOC_USP7_MATH_1 35 39 PF00917 0.600
DOC_USP7_MATH_1 79 83 PF00917 0.536
LIG_14-3-3_CanoR_1 135 144 PF00244 0.413
LIG_14-3-3_CanoR_1 162 167 PF00244 0.583
LIG_BIR_II_1 1 5 PF00653 0.540
LIG_DLG_GKlike_1 162 170 PF00625 0.579
LIG_FHA_1 71 77 PF00498 0.606
LIG_LIR_Nem_3 146 152 PF02991 0.572
LIG_PDZ_Class_1 177 182 PF00595 0.573
LIG_PTAP_UEV_1 44 49 PF05743 0.519
LIG_PTB_Apo_2 100 107 PF02174 0.474
LIG_PTB_Phospho_1 100 106 PF10480 0.478
LIG_SH3_3 39 45 PF00018 0.530
LIG_SUMO_SIM_anti_2 38 43 PF11976 0.529
MOD_CK1_1 138 144 PF00069 0.444
MOD_CK1_1 23 29 PF00069 0.602
MOD_CK1_1 40 46 PF00069 0.613
MOD_CK1_1 49 55 PF00069 0.568
MOD_CK1_1 57 63 PF00069 0.542
MOD_CK1_1 67 73 PF00069 0.631
MOD_GlcNHglycan 140 143 PF01048 0.428
MOD_GlcNHglycan 31 34 PF01048 0.592
MOD_GlcNHglycan 57 60 PF01048 0.648
MOD_GSK3_1 162 169 PF00069 0.575
MOD_GSK3_1 20 27 PF00069 0.594
MOD_GSK3_1 43 50 PF00069 0.693
MOD_GSK3_1 53 60 PF00069 0.590
MOD_GSK3_1 62 69 PF00069 0.643
MOD_GSK3_1 75 82 PF00069 0.505
MOD_GSK3_1 83 90 PF00069 0.366
MOD_N-GLC_1 62 67 PF02516 0.566
MOD_N-GLC_2 97 99 PF02516 0.506
MOD_NEK2_1 161 166 PF00069 0.604
MOD_NEK2_1 174 179 PF00069 0.566
MOD_NEK2_2 145 150 PF00069 0.465
MOD_OFUCOSY 114 120 PF10250 0.499
MOD_PKA_2 161 167 PF00069 0.585
MOD_Plk_1 23 29 PF00069 0.573
MOD_Plk_4 162 168 PF00069 0.695
MOD_Plk_4 37 43 PF00069 0.528

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H585 Leishmania donovani 88% 100%
A4H445 Leishmania braziliensis 36% 100%
A4HS15 Leishmania infantum 88% 100%
E9AK02 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS