Surface antigen-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

surface antigen-like protein

Species:

Leishmania major

UniProt:

Q9XZX8_LEIMA

TriTrypDb:

LmjF.04.0180 , LMJLV39_000014000 , LMJSD75_040006800

Length:

504

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 35

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 6, no: 4
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9XZX8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9XZX8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	121	123	PF00082	0.563
CLV_PCSK_PC1ET2_1	121	123	PF00082	0.563
CLV_PCSK_SKI1_1	154	158	PF00082	0.538
CLV_PCSK_SKI1_1	4	8	PF00082	0.716
DEG_APCC_DBOX_1	121	129	PF00400	0.339
DEG_APCC_DBOX_1	3	11	PF00400	0.532
DEG_Nend_UBRbox_1	1	4	PF02207	0.557
DEG_SCF_FBW7_1	317	322	PF00400	0.444
DOC_ANK_TNKS_1	33	40	PF00023	0.411
DOC_CKS1_1	316	321	PF01111	0.449

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H584	Leishmania donovani	93%	100%
A0A451EJW6	Leishmania donovani	71%	71%
A4H3U2	Leishmania braziliensis	65%	100%
A4H3Y2	Leishmania braziliensis	31%	88%
A4HS13	Leishmania infantum	94%	100%
A4HS14	Leishmania infantum	71%	71%
E9AK00	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
E9AK01	Leishmania mexicana (strain MHOM/GT/2001/U1103)	67%	71%
Q9XZX9	Leishmania major	73%	71%

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