Uncharacterized protein L1648.02

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

outer dynein arm docking complex, putative

Species:

Leishmania major

UniProt:

Q9U1E6_LEIMA

TriTrypDb:

LmjF.32.2900 , LMJLV39_320036600 , LMJSD75_320036800

Length:

618

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	2
GO:0005930	axoneme	2	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	2

Expansion

Sequence features

Q9U1E6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9U1E6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	196	200	PF00656	0.402
CLV_C14_Caspase3-7	567	571	PF00656	0.726
CLV_C14_Caspase3-7	74	78	PF00656	0.486
CLV_NRD_NRD_1	107	109	PF00675	0.407
CLV_NRD_NRD_1	163	165	PF00675	0.349
CLV_NRD_NRD_1	17	19	PF00675	0.403
CLV_NRD_NRD_1	274	276	PF00675	0.728
CLV_NRD_NRD_1	588	590	PF00675	0.458
CLV_NRD_NRD_1	607	609	PF00675	0.489
CLV_NRD_NRD_1	81	83	PF00675	0.437
CLV_NRD_NRD_1	88	90	PF00675	0.435
CLV_PCSK_KEX2_1	163	165	PF00082	0.408
CLV_PCSK_KEX2_1	17	19	PF00082	0.395
CLV_PCSK_KEX2_1	171	173	PF00082	0.415
CLV_PCSK_KEX2_1	181	183	PF00082	0.445
CLV_PCSK_KEX2_1	274	276	PF00082	0.683
CLV_PCSK_KEX2_1	81	83	PF00082	0.454
CLV_PCSK_KEX2_1	95	97	PF00082	0.435
CLV_PCSK_PC1ET2_1	171	173	PF00082	0.437
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.445
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.504
CLV_PCSK_SKI1_1	108	112	PF00082	0.427
CLV_PCSK_SKI1_1	163	167	PF00082	0.369
CLV_PCSK_SKI1_1	209	213	PF00082	0.428
CLV_PCSK_SKI1_1	358	362	PF00082	0.461
CLV_PCSK_SKI1_1	450	454	PF00082	0.513
CLV_PCSK_SKI1_1	595	599	PF00082	0.447
DEG_APCC_DBOX_1	95	103	PF00400	0.502
DEG_SPOP_SBC_1	288	292	PF00917	0.640
DEG_SPOP_SBC_1	481	485	PF00917	0.720
DOC_MAPK_gen_1	108	116	PF00069	0.496
DOC_MAPK_gen_1	150	158	PF00069	0.405
DOC_MAPK_gen_1	160	169	PF00069	0.411
DOC_MAPK_MEF2A_6	160	169	PF00069	0.412
DOC_MAPK_MEF2A_6	459	467	PF00069	0.510
DOC_USP7_MATH_1	270	274	PF00917	0.675
DOC_USP7_MATH_1	279	283	PF00917	0.700
DOC_USP7_MATH_1	482	486	PF00917	0.698
DOC_USP7_MATH_1	558	562	PF00917	0.693
DOC_USP7_UBL2_3	358	362	PF12436	0.505
DOC_WW_Pin1_4	490	495	PF00397	0.683
DOC_WW_Pin1_4	512	517	PF00397	0.650
DOC_WW_Pin1_4	529	534	PF00397	0.632
LIG_14-3-3_CanoR_1	17	25	PF00244	0.448
LIG_14-3-3_CanoR_1	416	425	PF00244	0.465
LIG_14-3-3_CanoR_1	443	449	PF00244	0.471
LIG_14-3-3_CanoR_1	459	467	PF00244	0.302
LIG_14-3-3_CanoR_1	478	482	PF00244	0.647
LIG_14-3-3_CanoR_1	595	600	PF00244	0.603
LIG_Actin_WH2_2	347	364	PF00022	0.422
LIG_Actin_WH2_2	396	413	PF00022	0.496
LIG_BIR_II_1	1	5	PF00653	0.494
LIG_Clathr_ClatBox_1	304	308	PF01394	0.494
LIG_FHA_1	218	224	PF00498	0.445
LIG_FHA_1	299	305	PF00498	0.685
LIG_FHA_1	313	319	PF00498	0.583
LIG_FHA_1	325	331	PF00498	0.435
LIG_FHA_1	333	339	PF00498	0.492
LIG_FHA_1	405	411	PF00498	0.419
LIG_FHA_1	459	465	PF00498	0.415
LIG_FHA_2	289	295	PF00498	0.746
LIG_FHA_2	418	424	PF00498	0.476
LIG_FHA_2	453	459	PF00498	0.379
LIG_FHA_2	565	571	PF00498	0.703
LIG_FHA_2	57	63	PF00498	0.546
LIG_FHA_2	596	602	PF00498	0.491
LIG_LIR_Gen_1	422	433	PF02991	0.539
LIG_LIR_Gen_1	59	69	PF02991	0.403
LIG_LIR_Nem_3	342	348	PF02991	0.421
LIG_LIR_Nem_3	422	428	PF02991	0.379
LIG_LIR_Nem_3	59	64	PF02991	0.418
LIG_NRBOX	367	373	PF00104	0.552
LIG_PCNA_yPIPBox_3	344	358	PF02747	0.399
LIG_Rb_LxCxE_1	299	316	PF01857	0.484
LIG_SH2_CRK	348	352	PF00017	0.386
LIG_SH2_CRK	61	65	PF00017	0.403
LIG_SH2_GRB2like	219	222	PF00017	0.393
LIG_SH2_GRB2like	350	353	PF00017	0.414
LIG_SH2_NCK_1	425	429	PF00017	0.530
LIG_SH2_SRC	425	428	PF00017	0.527
LIG_SH2_SRC	61	64	PF00017	0.405
LIG_SH2_STAP1	219	223	PF00017	0.433
LIG_SH2_STAT3	219	222	PF00017	0.493
LIG_SH2_STAT3	574	577	PF00017	0.686
LIG_SH2_STAT5	219	222	PF00017	0.561
LIG_SH2_STAT5	337	340	PF00017	0.488
LIG_SH2_STAT5	350	353	PF00017	0.346
LIG_SH2_STAT5	63	66	PF00017	0.390
LIG_SH3_3	530	536	PF00018	0.609
LIG_SUMO_SIM_anti_2	154	162	PF11976	0.377
LIG_TRAF2_1	266	269	PF00917	0.765
LIG_TRAF2_1	292	295	PF00917	0.650
LIG_TRAF2_1	455	458	PF00917	0.371
LIG_TYR_ITSM	57	64	PF00017	0.535
LIG_UBA3_1	230	234	PF00899	0.548
LIG_UBA3_1	317	322	PF00899	0.565
MOD_CDK_SPK_2	490	495	PF00069	0.757
MOD_CK1_1	474	480	PF00069	0.536
MOD_CK1_1	485	491	PF00069	0.697
MOD_CK1_1	54	60	PF00069	0.587
MOD_CK1_1	544	550	PF00069	0.741
MOD_CK1_1	71	77	PF00069	0.552
MOD_CK2_1	288	294	PF00069	0.757
MOD_CK2_1	452	458	PF00069	0.376
MOD_CK2_1	490	496	PF00069	0.687
MOD_CK2_1	595	601	PF00069	0.566
MOD_GlcNHglycan	281	284	PF01048	0.634
MOD_GlcNHglycan	310	313	PF01048	0.500
MOD_GlcNHglycan	353	357	PF01048	0.418
MOD_GlcNHglycan	473	476	PF01048	0.457
MOD_GlcNHglycan	52	56	PF01048	0.443
MOD_GlcNHglycan	543	546	PF01048	0.628
MOD_GlcNHglycan	558	561	PF01048	0.529
MOD_GSK3_1	12	19	PF00069	0.549
MOD_GSK3_1	308	315	PF00069	0.515
MOD_GSK3_1	476	483	PF00069	0.627
MOD_GSK3_1	506	513	PF00069	0.672
MOD_GSK3_1	564	571	PF00069	0.696
MOD_N-GLC_1	343	348	PF02516	0.363
MOD_N-GLC_1	510	515	PF02516	0.671
MOD_NEK2_1	104	109	PF00069	0.430
MOD_NEK2_1	135	140	PF00069	0.414
MOD_NEK2_1	16	21	PF00069	0.519
MOD_NEK2_1	258	263	PF00069	0.651
MOD_NEK2_1	343	348	PF00069	0.422
MOD_NEK2_1	361	366	PF00069	0.453
MOD_PIKK_1	16	22	PF00454	0.450
MOD_PIKK_1	488	494	PF00454	0.482
MOD_PKA_2	16	22	PF00069	0.452
MOD_PKA_2	308	314	PF00069	0.562
MOD_PKA_2	442	448	PF00069	0.477
MOD_PKA_2	458	464	PF00069	0.285
MOD_PKA_2	477	483	PF00069	0.570
MOD_PKA_2	485	491	PF00069	0.573
MOD_PKA_2	568	574	PF00069	0.770
MOD_Plk_1	135	141	PF00069	0.481
MOD_Plk_1	343	349	PF00069	0.394
MOD_Plk_1	51	57	PF00069	0.545
MOD_Plk_1	569	575	PF00069	0.650
MOD_Plk_2-3	324	330	PF00069	0.646
MOD_Plk_4	300	306	PF00069	0.700
MOD_Plk_4	313	319	PF00069	0.458
MOD_Plk_4	569	575	PF00069	0.764
MOD_ProDKin_1	490	496	PF00069	0.685
MOD_ProDKin_1	512	518	PF00069	0.650
MOD_ProDKin_1	529	535	PF00069	0.633
MOD_SUMO_for_1	356	359	PF00179	0.498
MOD_SUMO_for_1	49	52	PF00179	0.405
MOD_SUMO_rev_2	174	179	PF00179	0.450
MOD_SUMO_rev_2	227	236	PF00179	0.463
MOD_SUMO_rev_2	256	264	PF00179	0.552
MOD_SUMO_rev_2	391	400	PF00179	0.437
TRG_DiLeu_BaEn_3	161	167	PF01217	0.412
TRG_DiLeu_BaEn_4	503	509	PF01217	0.634
TRG_DiLeu_BaLyEn_6	367	372	PF01217	0.482
TRG_ENDOCYTIC_2	348	351	PF00928	0.398
TRG_ENDOCYTIC_2	425	428	PF00928	0.527
TRG_ENDOCYTIC_2	61	64	PF00928	0.405
TRG_ER_diArg_1	16	18	PF00400	0.432
TRG_ER_diArg_1	163	165	PF00400	0.363
TRG_ER_diArg_1	81	83	PF00400	0.452
TRG_NLS_Bipartite_1	163	184	PF00514	0.377
TRG_NLS_Bipartite_1	95	112	PF00514	0.485
TRG_NLS_MonoExtN_4	178	184	PF00514	0.414
TRG_Pf-PMV_PEXEL_1	370	374	PF00026	0.462
TRG_Pf-PMV_PEXEL_1	387	391	PF00026	0.288

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8M7	Leptomonas seymouri	70%	97%
A0A0S4IU95	Bodo saltans	34%	100%
A0A1X0NRP3	Trypanosomatidae	48%	90%
A0A3Q8IH93	Leishmania donovani	96%	100%
A0A3R7MTI3	Trypanosoma rangeli	42%	96%
A4HKT2	Leishmania braziliensis	84%	100%
A4I8B1	Leishmania infantum	96%	100%
A8JF70	Chlamydomonas reinhardtii	27%	100%
D0AAI2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	97%
E9B370	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
V5BMI0	Trypanosoma cruzi	42%	95%