Uncharacterized protein L1648.06

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9U1E2_LEIMA

TriTrypDb:

LmjF.32.2940 , LMJLV39_320037000 , LMJSD75_320037200

Length:

604

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9U1E2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9U1E2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	475	479	PF00656	0.276
CLV_C14_Caspase3-7	484	488	PF00656	0.481
CLV_NRD_NRD_1	129	131	PF00675	0.594
CLV_NRD_NRD_1	284	286	PF00675	0.362
CLV_NRD_NRD_1	397	399	PF00675	0.501
CLV_NRD_NRD_1	464	466	PF00675	0.376
CLV_NRD_NRD_1	567	569	PF00675	0.626
CLV_NRD_NRD_1	75	77	PF00675	0.526
CLV_PCSK_KEX2_1	210	212	PF00082	0.319
CLV_PCSK_KEX2_1	276	278	PF00082	0.301

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IBK1	Leptomonas seymouri	70%	100%
A0A1X0NRN7	Trypanosomatidae	58%	99%
A0A3R7NSK8	Trypanosoma rangeli	60%	100%
A0A3S7X5W5	Leishmania donovani	95%	100%
A4HKT6	Leishmania braziliensis	87%	100%
A4I8B5	Leishmania infantum	95%	100%
D0AAI7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	99%
E9B374	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5DE73	Trypanosoma cruzi	57%	100%

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