Uncharacterized protein L1648.11

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9U1D7_LEIMA

TriTrypDb:

LmjF.32.2985

Length:

198

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 8, no: 0
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9U1D7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9U1D7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	57	59	PF00675	0.417
CLV_NRD_NRD_1	79	81	PF00675	0.505
CLV_PCSK_KEX2_1	57	59	PF00082	0.568
CLV_PCSK_SKI1_1	38	42	PF00082	0.492
CLV_PCSK_SKI1_1	69	73	PF00082	0.571
DEG_Nend_UBRbox_3	1	3	PF02207	0.574
DOC_MAPK_MEF2A_6	104	112	PF00069	0.487
DOC_USP7_MATH_1	40	44	PF00917	0.517
DOC_USP7_UBL2_3	38	42	PF12436	0.447
LIG_14-3-3_CanoR_1	152	156	PF00244	0.490
LIG_14-3-3_CanoR_1	58	64	PF00244	0.454
LIG_14-3-3_CanoR_1	80	88	PF00244	0.491
LIG_BRCT_BRCA1_1	168	172	PF00533	0.351
LIG_FHA_1	145	151	PF00498	0.437
LIG_FHA_1	180	186	PF00498	0.456
LIG_FHA_1	4	10	PF00498	0.530
LIG_FHA_1	54	60	PF00498	0.416
LIG_LIR_Apic_2	100	106	PF02991	0.451
LIG_LIR_Gen_1	154	162	PF02991	0.445
LIG_LIR_Gen_1	169	176	PF02991	0.344
LIG_LIR_LC3C_4	6	9	PF02991	0.427
LIG_LIR_Nem_3	154	158	PF02991	0.444
LIG_LIR_Nem_3	169	175	PF02991	0.272
LIG_SH2_CRK	103	107	PF00017	0.514
LIG_SH2_CRK	155	159	PF00017	0.462
LIG_SH2_CRK	170	174	PF00017	0.378
LIG_SH2_CRK	60	64	PF00017	0.385
LIG_SH2_SRC	118	121	PF00017	0.367
LIG_SH2_SRC	124	127	PF00017	0.382
LIG_SH2_STAT5	118	121	PF00017	0.367
LIG_SH2_STAT5	124	127	PF00017	0.382
LIG_SH2_STAT5	155	158	PF00017	0.544
LIG_SH2_STAT5	83	86	PF00017	0.537
LIG_SUMO_SIM_par_1	5	10	PF11976	0.471
LIG_TYR_ITIM	122	127	PF00017	0.436
MOD_CK1_1	62	68	PF00069	0.460
MOD_CK2_1	160	166	PF00069	0.564
MOD_GlcNHglycan	162	165	PF01048	0.497
MOD_GSK3_1	140	147	PF00069	0.444
MOD_GSK3_1	184	191	PF00069	0.448
MOD_GSK3_1	3	10	PF00069	0.517
MOD_GSK3_1	47	54	PF00069	0.507
MOD_GSK3_1	83	90	PF00069	0.476
MOD_GSK3_1	95	102	PF00069	0.367
MOD_N-GLC_1	51	56	PF02516	0.459
MOD_NEK2_1	144	149	PF00069	0.350
MOD_NEK2_1	3	8	PF00069	0.524
MOD_PIKK_1	87	93	PF00454	0.568
MOD_PKA_2	140	146	PF00069	0.459
MOD_PKA_2	151	157	PF00069	0.492
MOD_PKB_1	97	105	PF00069	0.438
MOD_Plk_1	22	28	PF00069	0.607
MOD_Plk_2-3	22	28	PF00069	0.607
MOD_Plk_4	140	146	PF00069	0.565
MOD_Plk_4	59	65	PF00069	0.369
MOD_SUMO_rev_2	74	82	PF00179	0.460
TRG_ENDOCYTIC_2	124	127	PF00928	0.505
TRG_ENDOCYTIC_2	155	158	PF00928	0.500
TRG_ENDOCYTIC_2	170	173	PF00928	0.251
TRG_ENDOCYTIC_2	60	63	PF00928	0.407
TRG_ER_diArg_1	57	59	PF00400	0.428
TRG_Pf-PMV_PEXEL_1	174	178	PF00026	0.433

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NRP9	Trypanosomatidae	39%	99%
A0A3Q8IFP0	Leishmania donovani	91%	100%
A0A422NZW7	Trypanosoma rangeli	39%	99%
A4HKU2	Leishmania braziliensis	78%	99%
A4I8C1	Leishmania infantum	91%	100%
D0AAJ3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	99%
E9B380	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%