RSN1_TM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9U0Z7_LEIMA

TriTrypDb:

LmjF.04.0860 , LMJLV39_040014000 , LMJSD75_040014300

Length:

409

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

Q9U0Z7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9U0Z7

PDB structure(s): 7aih_S , 7am2_S , 7ane_S

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.559
CLV_C14_Caspase3-7	31	35	PF00656	0.476
CLV_MEL_PAP_1	60	66	PF00089	0.564
CLV_NRD_NRD_1	149	151	PF00675	0.702
CLV_NRD_NRD_1	2	4	PF00675	0.609
CLV_NRD_NRD_1	205	207	PF00675	0.805
CLV_NRD_NRD_1	252	254	PF00675	0.656
CLV_NRD_NRD_1	297	299	PF00675	0.598
CLV_NRD_NRD_1	362	364	PF00675	0.663
CLV_NRD_NRD_1	72	74	PF00675	0.607

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4H3Z6	Leishmania braziliensis	65%	100%
E9AK69	Leishmania mexicana (strain MHOM/GT/2001/U1103)	67%	100%

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