Uncharacterized protein L7836.06

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q9U0V6_LEIMA

TriTrypDb:

LmjF.23.0660 , LMJLV39_230015100 , LMJSD75_230015400

Length:

887

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9U0V6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9U0V6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	442	446	PF00656	0.587
CLV_C14_Caspase3-7	854	858	PF00656	0.659
CLV_NRD_NRD_1	140	142	PF00675	0.573
CLV_NRD_NRD_1	375	377	PF00675	0.737
CLV_NRD_NRD_1	386	388	PF00675	0.418
CLV_NRD_NRD_1	393	395	PF00675	0.604
CLV_NRD_NRD_1	579	581	PF00675	0.567
CLV_NRD_NRD_1	755	757	PF00675	0.599
CLV_NRD_NRD_1	831	833	PF00675	0.648
CLV_PCSK_FUR_1	829	833	PF00082	0.645
CLV_PCSK_KEX2_1	364	366	PF00082	0.599
CLV_PCSK_KEX2_1	375	377	PF00082	0.503
CLV_PCSK_KEX2_1	393	395	PF00082	0.672
CLV_PCSK_KEX2_1	579	581	PF00082	0.567
CLV_PCSK_KEX2_1	755	757	PF00082	0.599
CLV_PCSK_KEX2_1	831	833	PF00082	0.648
CLV_PCSK_PC1ET2_1	364	366	PF00082	0.599
CLV_PCSK_SKI1_1	124	128	PF00082	0.565
CLV_PCSK_SKI1_1	322	326	PF00082	0.475
CLV_PCSK_SKI1_1	364	368	PF00082	0.528
CLV_PCSK_SKI1_1	393	397	PF00082	0.632
CLV_PCSK_SKI1_1	411	415	PF00082	0.550
CLV_PCSK_SKI1_1	417	421	PF00082	0.705
CLV_PCSK_SKI1_1	648	652	PF00082	0.627
CLV_PCSK_SKI1_1	661	665	PF00082	0.584
CLV_PCSK_SKI1_1	740	744	PF00082	0.677
DEG_APCC_DBOX_1	321	329	PF00400	0.466
DEG_SCF_FBW7_1	286	293	PF00400	0.605
DEG_SCF_FBW7_1	476	483	PF00400	0.684
DEG_SCF_FBW7_2	491	498	PF00400	0.640
DEG_SPOP_SBC_1	209	213	PF00917	0.648
DOC_AGCK_PIF_2	438	443	PF00069	0.547
DOC_ANK_TNKS_1	179	186	PF00023	0.610
DOC_ANK_TNKS_1	54	61	PF00023	0.532
DOC_ANK_TNKS_1	84	91	PF00023	0.463
DOC_MAPK_DCC_7	580	590	PF00069	0.568
DOC_MAPK_gen_1	755	762	PF00069	0.615
DOC_MAPK_MEF2A_6	174	181	PF00069	0.653
DOC_MAPK_MEF2A_6	79	88	PF00069	0.499
DOC_PP1_RVXF_1	152	159	PF00149	0.617
DOC_PP2B_LxvP_1	488	491	PF13499	0.653
DOC_USP7_MATH_1	120	124	PF00917	0.654
DOC_USP7_MATH_1	16	20	PF00917	0.540
DOC_USP7_MATH_1	292	296	PF00917	0.592
DOC_USP7_MATH_1	431	435	PF00917	0.596
DOC_USP7_MATH_1	455	459	PF00917	0.562
DOC_USP7_MATH_1	471	475	PF00917	0.578
DOC_USP7_MATH_1	515	519	PF00917	0.584
DOC_USP7_MATH_1	538	542	PF00917	0.611
DOC_USP7_MATH_1	543	547	PF00917	0.617
DOC_USP7_MATH_1	619	623	PF00917	0.561
DOC_USP7_MATH_1	674	678	PF00917	0.665
DOC_USP7_MATH_1	681	685	PF00917	0.612
DOC_USP7_MATH_1	695	699	PF00917	0.605
DOC_USP7_MATH_1	709	713	PF00917	0.607
DOC_USP7_MATH_1	733	737	PF00917	0.646
DOC_USP7_MATH_1	844	848	PF00917	0.592
DOC_USP7_MATH_1	883	887	PF00917	0.553
DOC_USP7_UBL2_3	360	364	PF12436	0.605
DOC_USP7_UBL2_3	398	402	PF12436	0.643
DOC_USP7_UBL2_3	496	500	PF12436	0.642
DOC_WW_Pin1_4	286	291	PF00397	0.657
DOC_WW_Pin1_4	405	410	PF00397	0.674
DOC_WW_Pin1_4	476	481	PF00397	0.680
DOC_WW_Pin1_4	491	496	PF00397	0.563
DOC_WW_Pin1_4	532	537	PF00397	0.594
DOC_WW_Pin1_4	617	622	PF00397	0.487
DOC_WW_Pin1_4	672	677	PF00397	0.734
DOC_WW_Pin1_4	679	684	PF00397	0.645
DOC_WW_Pin1_4	707	712	PF00397	0.665
DOC_WW_Pin1_4	744	749	PF00397	0.605
DOC_WW_Pin1_4	786	791	PF00397	0.625
DOC_WW_Pin1_4	80	85	PF00397	0.619
LIG_14-3-3_CanoR_1	108	112	PF00244	0.546
LIG_14-3-3_CanoR_1	254	264	PF00244	0.640
LIG_14-3-3_CanoR_1	31	40	PF00244	0.572
LIG_14-3-3_CanoR_1	375	383	PF00244	0.527
LIG_14-3-3_CanoR_1	387	391	PF00244	0.423
LIG_14-3-3_CanoR_1	615	624	PF00244	0.533
LIG_14-3-3_CanoR_1	740	748	PF00244	0.649
LIG_14-3-3_CanoR_1	829	839	PF00244	0.644
LIG_Actin_WH2_2	437	455	PF00022	0.651
LIG_BIR_II_1	1	5	PF00653	0.550
LIG_BIR_III_4	454	458	PF00653	0.684
LIG_BRCT_BRCA1_1	18	22	PF00533	0.615
LIG_BRCT_BRCA1_1	237	241	PF00533	0.559
LIG_FHA_1	204	210	PF00498	0.699
LIG_FHA_1	27	33	PF00498	0.558
LIG_FHA_1	658	664	PF00498	0.781
LIG_FHA_1	702	708	PF00498	0.583
LIG_FHA_1	741	747	PF00498	0.715
LIG_FHA_1	81	87	PF00498	0.550
LIG_FHA_2	566	572	PF00498	0.534
LIG_FHA_2	599	605	PF00498	0.608
LIG_FHA_2	639	645	PF00498	0.622
LIG_LIR_Apic_2	566	570	PF02991	0.529
LIG_LIR_Gen_1	235	245	PF02991	0.560
LIG_LIR_Gen_1	418	428	PF02991	0.769
LIG_LIR_Gen_1	439	448	PF02991	0.625
LIG_LIR_Gen_1	552	562	PF02991	0.496
LIG_LIR_Gen_1	620	631	PF02991	0.514
LIG_LIR_Gen_1	773	781	PF02991	0.637
LIG_LIR_Nem_3	2	6	PF02991	0.553
LIG_LIR_Nem_3	235	240	PF02991	0.562
LIG_LIR_Nem_3	418	423	PF02991	0.768
LIG_LIR_Nem_3	48	53	PF02991	0.625
LIG_LIR_Nem_3	552	558	PF02991	0.497
LIG_LIR_Nem_3	593	598	PF02991	0.612
LIG_LIR_Nem_3	620	626	PF02991	0.530
LIG_LIR_Nem_3	773	777	PF02991	0.655
LIG_LIR_Nem_3	798	802	PF02991	0.653
LIG_MLH1_MIPbox_1	237	241	PF16413	0.559
LIG_NRBOX	324	330	PF00104	0.534
LIG_PALB2_WD40_1	235	243	PF16756	0.582
LIG_Pex14_1	237	241	PF04695	0.582
LIG_Pex14_2	96	100	PF04695	0.510
LIG_PTAP_UEV_1	729	734	PF05743	0.608
LIG_PTB_Apo_2	800	807	PF02174	0.588
LIG_PTB_Phospho_1	800	806	PF10480	0.590
LIG_SH2_CRK	159	163	PF00017	0.576
LIG_SH2_GRB2like	806	809	PF00017	0.634
LIG_SH2_STAT5	308	311	PF00017	0.604
LIG_SH2_STAT5	623	626	PF00017	0.499
LIG_SH3_3	178	184	PF00018	0.636
LIG_SH3_3	258	264	PF00018	0.525
LIG_SH3_3	663	669	PF00018	0.602
LIG_SH3_3	705	711	PF00018	0.609
LIG_SH3_3	727	733	PF00018	0.583
LIG_SH3_4	360	367	PF00018	0.594
LIG_SUMO_SIM_anti_2	302	308	PF11976	0.527
LIG_SUMO_SIM_anti_2	556	562	PF11976	0.560
LIG_SUMO_SIM_par_1	662	667	PF11976	0.599
LIG_TRAF2_1	224	227	PF00917	0.594
LIG_TRAF2_1	605	608	PF00917	0.554
LIG_TRFH_1	241	245	PF08558	0.533
LIG_UBA3_1	325	333	PF00899	0.642
MOD_CDC14_SPxK_1	408	411	PF00782	0.634
MOD_CDK_SPK_2	491	496	PF00069	0.639
MOD_CDK_SPK_2	786	791	PF00069	0.639
MOD_CDK_SPK_2	80	85	PF00069	0.619
MOD_CDK_SPxK_1	405	411	PF00069	0.639
MOD_CK1_1	164	170	PF00069	0.531
MOD_CK1_1	200	206	PF00069	0.637
MOD_CK1_1	213	219	PF00069	0.748
MOD_CK1_1	246	252	PF00069	0.721
MOD_CK1_1	257	263	PF00069	0.577
MOD_CK1_1	278	284	PF00069	0.608
MOD_CK1_1	285	291	PF00069	0.652
MOD_CK1_1	296	302	PF00069	0.624
MOD_CK1_1	34	40	PF00069	0.630
MOD_CK1_1	342	348	PF00069	0.446
MOD_CK1_1	404	410	PF00069	0.648
MOD_CK1_1	418	424	PF00069	0.806
MOD_CK1_1	474	480	PF00069	0.642
MOD_CK1_1	675	681	PF00069	0.670
MOD_CK1_1	699	705	PF00069	0.637
MOD_CK1_1	712	718	PF00069	0.587
MOD_CK1_1	747	753	PF00069	0.681
MOD_CK1_1	789	795	PF00069	0.640
MOD_CK1_1	847	853	PF00069	0.648
MOD_CK2_1	292	298	PF00069	0.535
MOD_CK2_1	598	604	PF00069	0.605
MOD_Cter_Amidation	829	832	PF01082	0.644
MOD_GlcNHglycan	143	146	PF01048	0.509
MOD_GlcNHglycan	166	169	PF01048	0.601
MOD_GlcNHglycan	206	209	PF01048	0.646
MOD_GlcNHglycan	216	219	PF01048	0.563
MOD_GlcNHglycan	245	248	PF01048	0.655
MOD_GlcNHglycan	267	270	PF01048	0.562
MOD_GlcNHglycan	277	280	PF01048	0.691
MOD_GlcNHglycan	294	298	PF01048	0.552
MOD_GlcNHglycan	341	344	PF01048	0.526
MOD_GlcNHglycan	36	39	PF01048	0.642
MOD_GlcNHglycan	378	381	PF01048	0.513
MOD_GlcNHglycan	404	407	PF01048	0.605
MOD_GlcNHglycan	417	420	PF01048	0.587
MOD_GlcNHglycan	458	461	PF01048	0.817
MOD_GlcNHglycan	503	506	PF01048	0.695
MOD_GlcNHglycan	540	543	PF01048	0.595
MOD_GlcNHglycan	56	59	PF01048	0.593
MOD_GlcNHglycan	6	9	PF01048	0.619
MOD_GlcNHglycan	604	607	PF01048	0.647
MOD_GlcNHglycan	617	620	PF01048	0.625
MOD_GlcNHglycan	634	637	PF01048	0.492
MOD_GlcNHglycan	65	68	PF01048	0.554
MOD_GlcNHglycan	683	686	PF01048	0.624
MOD_GlcNHglycan	711	714	PF01048	0.788
MOD_GlcNHglycan	721	724	PF01048	0.643
MOD_GlcNHglycan	74	77	PF01048	0.721
MOD_GlcNHglycan	749	752	PF01048	0.680
MOD_GlcNHglycan	763	766	PF01048	0.545
MOD_GlcNHglycan	786	789	PF01048	0.635
MOD_GlcNHglycan	791	794	PF01048	0.597
MOD_GlcNHglycan	846	849	PF01048	0.618
MOD_GlcNHglycan	859	862	PF01048	0.503
MOD_GlcNHglycan	880	883	PF01048	0.542
MOD_GSK3_1	16	23	PF00069	0.641
MOD_GSK3_1	200	207	PF00069	0.576
MOD_GSK3_1	209	216	PF00069	0.725
MOD_GSK3_1	235	242	PF00069	0.663
MOD_GSK3_1	26	33	PF00069	0.770
MOD_GSK3_1	265	272	PF00069	0.690
MOD_GSK3_1	278	285	PF00069	0.578
MOD_GSK3_1	286	293	PF00069	0.690
MOD_GSK3_1	34	41	PF00069	0.503
MOD_GSK3_1	401	408	PF00069	0.635
MOD_GSK3_1	415	422	PF00069	0.586
MOD_GSK3_1	472	479	PF00069	0.629
MOD_GSK3_1	480	487	PF00069	0.578
MOD_GSK3_1	496	503	PF00069	0.530
MOD_GSK3_1	598	605	PF00069	0.583
MOD_GSK3_1	615	622	PF00069	0.575
MOD_GSK3_1	675	682	PF00069	0.648
MOD_GSK3_1	695	702	PF00069	0.556
MOD_GSK3_1	703	710	PF00069	0.730
MOD_GSK3_1	712	719	PF00069	0.559
MOD_GSK3_1	721	728	PF00069	0.545
MOD_GSK3_1	740	747	PF00069	0.624
MOD_GSK3_1	874	881	PF00069	0.517
MOD_N-GLC_1	164	169	PF02516	0.620
MOD_N-GLC_1	254	259	PF02516	0.535
MOD_N-GLC_1	725	730	PF02516	0.559
MOD_N-GLC_1	781	786	PF02516	0.685
MOD_NEK2_1	107	112	PF00069	0.496
MOD_NEK2_1	127	132	PF00069	0.447
MOD_NEK2_1	265	270	PF00069	0.649
MOD_NEK2_1	386	391	PF00069	0.606
MOD_NEK2_1	443	448	PF00069	0.581
MOD_NEK2_1	565	570	PF00069	0.518
MOD_NEK2_1	624	629	PF00069	0.550
MOD_NEK2_1	651	656	PF00069	0.647
MOD_NEK2_1	701	706	PF00069	0.603
MOD_NEK2_1	781	786	PF00069	0.617
MOD_NEK2_1	801	806	PF00069	0.587
MOD_NEK2_2	436	441	PF00069	0.646
MOD_PIKK_1	31	37	PF00454	0.629
MOD_PIKK_1	381	387	PF00454	0.542
MOD_PIKK_1	740	746	PF00454	0.604
MOD_PIKK_1	776	782	PF00454	0.663
MOD_PKA_1	141	147	PF00069	0.577
MOD_PKA_1	393	399	PF00069	0.675
MOD_PKA_2	107	113	PF00069	0.549
MOD_PKA_2	127	133	PF00069	0.444
MOD_PKA_2	26	32	PF00069	0.635
MOD_PKA_2	386	392	PF00069	0.582
MOD_PKA_2	393	399	PF00069	0.574
MOD_PKA_2	54	60	PF00069	0.655
MOD_PKA_2	78	84	PF00069	0.572
MOD_PKA_2	825	831	PF00069	0.669
MOD_Plk_1	471	477	PF00069	0.643
MOD_Plk_1	725	731	PF00069	0.560
MOD_Plk_1	758	764	PF00069	0.604
MOD_Plk_4	210	216	PF00069	0.659
MOD_Plk_4	296	302	PF00069	0.650
MOD_Plk_4	515	521	PF00069	0.653
MOD_Plk_4	619	625	PF00069	0.546
MOD_Plk_4	696	702	PF00069	0.633
MOD_Plk_4	703	709	PF00069	0.586
MOD_Plk_4	874	880	PF00069	0.542
MOD_Plk_4	91	97	PF00069	0.656
MOD_ProDKin_1	286	292	PF00069	0.656
MOD_ProDKin_1	405	411	PF00069	0.675
MOD_ProDKin_1	476	482	PF00069	0.681
MOD_ProDKin_1	491	497	PF00069	0.564
MOD_ProDKin_1	532	538	PF00069	0.595
MOD_ProDKin_1	617	623	PF00069	0.483
MOD_ProDKin_1	672	678	PF00069	0.734
MOD_ProDKin_1	679	685	PF00069	0.646
MOD_ProDKin_1	707	713	PF00069	0.665
MOD_ProDKin_1	744	750	PF00069	0.602
MOD_ProDKin_1	786	792	PF00069	0.623
MOD_ProDKin_1	80	86	PF00069	0.611
MOD_SUMO_for_1	495	498	PF00179	0.664
MOD_SUMO_rev_2	116	121	PF00179	0.605
MOD_SUMO_rev_2	138	144	PF00179	0.519
MOD_SUMO_rev_2	198	203	PF00179	0.618
MOD_SUMO_rev_2	604	611	PF00179	0.626
TRG_DiLeu_BaEn_1	305	310	PF01217	0.579
TRG_DiLeu_BaLyEn_6	666	671	PF01217	0.615
TRG_ENDOCYTIC_2	595	598	PF00928	0.565
TRG_ENDOCYTIC_2	623	626	PF00928	0.499
TRG_ER_diArg_1	24	27	PF00400	0.623
TRG_ER_diArg_1	392	394	PF00400	0.668
TRG_ER_diArg_1	829	832	PF00400	0.685
TRG_PTS1	884	887	PF00515	0.574

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I942	Leptomonas seymouri	37%	97%
A0A3S7WXM2	Leishmania donovani	91%	100%
A4HCT7	Leishmania braziliensis	70%	100%
A4I0B7	Leishmania infantum	91%	100%
E9AW81	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%