by homology
Contact email: najma.rachidi@pasteur.fr
Publication title: Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay
Publication 1st author(s): Despina Smirlis
Publication Identifier(s): 35047509
Host organism: -1
Interaction detection method(s): MI:0423
Interaction type: MI:0414
Identification method participant A: autoradiography
Identification method participant B: predetermined participant
ID(s) interactor A: Q15545
ID(s) interactor B: Q9NHE1
Taxid interactor A: Homo sapiens
Taxid interactor B: Leishmania major
Biological role(s) interactor A: enzyme target
Biological role(s) interactor B: enzyme
Experimental role(s) interactor A: neutral component
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 4 |
| Forrest at al. (procyclic) | no | yes: 4 |
| Silverman et al. | no | yes: 2 |
| Pissara et al. | yes | yes: 20 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 4 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 8 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 17 |
| NetGPI | no | yes: 0, no: 17 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 3 |
| GO:0005737 | cytoplasm | 2 | 3 |
| GO:0043226 | organelle | 2 | 3 |
| GO:0043227 | membrane-bounded organelle | 3 | 3 |
| GO:0043229 | intracellular organelle | 3 | 3 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 3 |
| GO:0110165 | cellular anatomical entity | 1 | 3 |
| GO:0031974 | membrane-enclosed lumen | 2 | 1 |
| GO:0031981 | nuclear lumen | 5 | 1 |
| GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 1 |
| GO:0043233 | organelle lumen | 3 | 1 |
| GO:0070013 | intracellular organelle lumen | 4 | 1 |
| GO:0097014 | ciliary plasm | 5 | 1 |
| GO:0099568 | cytoplasmic region | 3 | 1 |
Related structures:
AlphaFold database: Q9NHE2
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | 5 | 18 |
| GO:0006793 | phosphorus metabolic process | 3 | 18 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 18 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 18 |
| GO:0006810 | transport | 3 | 3 |
| GO:0006897 | endocytosis | 5 | 3 |
| GO:0007165 | signal transduction | 2 | 3 |
| GO:0008152 | metabolic process | 1 | 18 |
| GO:0009987 | cellular process | 1 | 18 |
| GO:0016192 | vesicle-mediated transport | 4 | 3 |
| GO:0016310 | phosphorylation | 5 | 18 |
| GO:0018105 | peptidyl-serine phosphorylation | 6 | 3 |
| GO:0018193 | peptidyl-amino acid modification | 5 | 3 |
| GO:0018209 | peptidyl-serine modification | 6 | 3 |
| GO:0019538 | protein metabolic process | 3 | 18 |
| GO:0036211 | protein modification process | 4 | 18 |
| GO:0043170 | macromolecule metabolic process | 3 | 18 |
| GO:0043412 | macromolecule modification | 4 | 18 |
| GO:0044237 | cellular metabolic process | 2 | 18 |
| GO:0044238 | primary metabolic process | 2 | 18 |
| GO:0050789 | regulation of biological process | 2 | 3 |
| GO:0050794 | regulation of cellular process | 3 | 3 |
| GO:0051179 | localization | 1 | 3 |
| GO:0051234 | establishment of localization | 2 | 3 |
| GO:0065007 | biological regulation | 1 | 3 |
| GO:0071704 | organic substance metabolic process | 2 | 18 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 18 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000166 | nucleotide binding | 3 | 18 |
| GO:0003824 | catalytic activity | 1 | 18 |
| GO:0004672 | protein kinase activity | 3 | 18 |
| GO:0004674 | protein serine/threonine kinase activity | 4 | 18 |
| GO:0005488 | binding | 1 | 18 |
| GO:0005524 | ATP binding | 5 | 18 |
| GO:0016301 | kinase activity | 4 | 18 |
| GO:0016740 | transferase activity | 2 | 18 |
| GO:0016772 | transferase activity, transferring phosphorus-containing groups | 3 | 18 |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 4 | 18 |
| GO:0017076 | purine nucleotide binding | 4 | 18 |
| GO:0030554 | adenyl nucleotide binding | 5 | 18 |
| GO:0032553 | ribonucleotide binding | 3 | 18 |
| GO:0032555 | purine ribonucleotide binding | 4 | 18 |
| GO:0032559 | adenyl ribonucleotide binding | 5 | 18 |
| GO:0035639 | purine ribonucleoside triphosphate binding | 4 | 18 |
| GO:0036094 | small molecule binding | 2 | 18 |
| GO:0043167 | ion binding | 2 | 18 |
| GO:0043168 | anion binding | 3 | 18 |
| GO:0097159 | organic cyclic compound binding | 2 | 18 |
| GO:0097367 | carbohydrate derivative binding | 2 | 18 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 18 |
| GO:1901265 | nucleoside phosphate binding | 3 | 18 |
| GO:1901363 | heterocyclic compound binding | 2 | 18 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 19 | 21 | PF00675 | 0.438 |
| CLV_NRD_NRD_1 | 201 | 203 | PF00675 | 0.339 |
| CLV_NRD_NRD_1 | 231 | 233 | PF00675 | 0.480 |
| CLV_NRD_NRD_1 | 283 | 285 | PF00675 | 0.499 |
| CLV_NRD_NRD_1 | 312 | 314 | PF00675 | 0.657 |
| CLV_PCSK_KEX2_1 | 19 | 21 | PF00082 | 0.438 |
| CLV_PCSK_KEX2_1 | 201 | 203 | PF00082 | 0.339 |
| CLV_PCSK_KEX2_1 | 283 | 285 | PF00082 | 0.419 |
| CLV_PCSK_KEX2_1 | 318 | 320 | PF00082 | 0.617 |
| CLV_PCSK_PC1ET2_1 | 318 | 320 | PF00082 | 0.619 |
| CLV_PCSK_PC7_1 | 279 | 285 | PF00082 | 0.484 |
| CLV_PCSK_SKI1_1 | 136 | 140 | PF00082 | 0.334 |
| CLV_PCSK_SKI1_1 | 180 | 184 | PF00082 | 0.339 |
| CLV_PCSK_SKI1_1 | 279 | 283 | PF00082 | 0.387 |
| DOC_CYCLIN_RxL_1 | 262 | 271 | PF00134 | 0.415 |
| DOC_CYCLIN_RxL_1 | 279 | 289 | PF00134 | 0.407 |
| DOC_MAPK_gen_1 | 149 | 156 | PF00069 | 0.338 |
| DOC_PP1_RVXF_1 | 263 | 270 | PF00149 | 0.413 |
| DOC_USP7_MATH_1 | 197 | 201 | PF00917 | 0.296 |
| DOC_USP7_MATH_1 | 240 | 244 | PF00917 | 0.310 |
| DOC_USP7_MATH_2 | 254 | 260 | PF00917 | 0.425 |
| DOC_USP7_UBL2_3 | 314 | 318 | PF12436 | 0.587 |
| LIG_14-3-3_CanoR_1 | 108 | 112 | PF00244 | 0.341 |
| LIG_14-3-3_CanoR_1 | 226 | 234 | PF00244 | 0.357 |
| LIG_14-3-3_CanoR_1 | 47 | 56 | PF00244 | 0.414 |
| LIG_14-3-3_CanoR_1 | 60 | 65 | PF00244 | 0.425 |
| LIG_Actin_WH2_2 | 204 | 219 | PF00022 | 0.353 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.523 |
| LIG_CtBP_PxDLS_1 | 254 | 258 | PF00389 | 0.256 |
| LIG_FHA_1 | 112 | 118 | PF00498 | 0.340 |
| LIG_FHA_1 | 35 | 41 | PF00498 | 0.385 |
| LIG_FHA_2 | 242 | 248 | PF00498 | 0.441 |
| LIG_GBD_Chelix_1 | 208 | 216 | PF00786 | 0.451 |
| LIG_LIR_Gen_1 | 185 | 195 | PF02991 | 0.339 |
| LIG_LIR_Gen_1 | 231 | 242 | PF02991 | 0.442 |
| LIG_LIR_Gen_1 | 83 | 94 | PF02991 | 0.341 |
| LIG_LIR_Nem_3 | 185 | 191 | PF02991 | 0.353 |
| LIG_LIR_Nem_3 | 219 | 225 | PF02991 | 0.339 |
| LIG_LIR_Nem_3 | 231 | 237 | PF02991 | 0.441 |
| LIG_LIR_Nem_3 | 25 | 29 | PF02991 | 0.356 |
| LIG_LIR_Nem_3 | 259 | 263 | PF02991 | 0.382 |
| LIG_LIR_Nem_3 | 274 | 278 | PF02991 | 0.401 |
| LIG_LIR_Nem_3 | 280 | 285 | PF02991 | 0.388 |
| LIG_LIR_Nem_3 | 58 | 64 | PF02991 | 0.358 |
| LIG_Pex14_2 | 26 | 30 | PF04695 | 0.369 |
| LIG_Pex14_2 | 282 | 286 | PF04695 | 0.397 |
| LIG_SH2_CRK | 188 | 192 | PF00017 | 0.342 |
| LIG_SH2_CRK | 234 | 238 | PF00017 | 0.423 |
| LIG_SH2_CRK | 275 | 279 | PF00017 | 0.380 |
| LIG_SH2_CRK | 62 | 66 | PF00017 | 0.342 |
| LIG_SH2_NCK_1 | 234 | 238 | PF00017 | 0.435 |
| LIG_SH2_STAP1 | 234 | 238 | PF00017 | 0.341 |
| LIG_SH2_STAP1 | 263 | 267 | PF00017 | 0.345 |
| LIG_SH2_STAP1 | 297 | 301 | PF00017 | 0.503 |
| LIG_SH2_STAT5 | 155 | 158 | PF00017 | 0.336 |
| LIG_SH2_STAT5 | 188 | 191 | PF00017 | 0.328 |
| LIG_SH2_STAT5 | 210 | 213 | PF00017 | 0.339 |
| LIG_SH2_STAT5 | 214 | 217 | PF00017 | 0.339 |
| LIG_SH2_STAT5 | 277 | 280 | PF00017 | 0.454 |
| LIG_SH2_STAT5 | 295 | 298 | PF00017 | 0.406 |
| LIG_SH2_STAT5 | 62 | 65 | PF00017 | 0.296 |
| LIG_SUMO_SIM_par_1 | 113 | 119 | PF11976 | 0.339 |
| LIG_SUMO_SIM_par_1 | 253 | 259 | PF11976 | 0.260 |
| LIG_TYR_ITIM | 208 | 213 | PF00017 | 0.387 |
| LIG_WRC_WIRS_1 | 257 | 262 | PF05994 | 0.452 |
| MOD_CK1_1 | 110 | 116 | PF00069 | 0.342 |
| MOD_CK1_1 | 190 | 196 | PF00069 | 0.339 |
| MOD_CK1_1 | 245 | 251 | PF00069 | 0.431 |
| MOD_CK2_1 | 22 | 28 | PF00069 | 0.387 |
| MOD_CK2_1 | 225 | 231 | PF00069 | 0.334 |
| MOD_CK2_1 | 241 | 247 | PF00069 | 0.413 |
| MOD_CK2_1 | 300 | 306 | PF00069 | 0.479 |
| MOD_CK2_1 | 79 | 85 | PF00069 | 0.296 |
| MOD_Cter_Amidation | 147 | 150 | PF01082 | 0.353 |
| MOD_Cter_Amidation | 17 | 20 | PF01082 | 0.438 |
| MOD_Cter_Amidation | 319 | 322 | PF01082 | 0.681 |
| MOD_GlcNHglycan | 2 | 5 | PF01048 | 0.384 |
| MOD_GSK3_1 | 107 | 114 | PF00069 | 0.342 |
| MOD_GSK3_1 | 178 | 185 | PF00069 | 0.353 |
| MOD_GSK3_1 | 241 | 248 | PF00069 | 0.371 |
| MOD_GSK3_1 | 300 | 307 | PF00069 | 0.550 |
| MOD_GSK3_1 | 56 | 63 | PF00069 | 0.323 |
| MOD_LATS_1 | 239 | 245 | PF00433 | 0.367 |
| MOD_N-GLC_1 | 261 | 266 | PF02516 | 0.383 |
| MOD_NEK2_1 | 111 | 116 | PF00069 | 0.357 |
| MOD_NEK2_1 | 127 | 132 | PF00069 | 0.301 |
| MOD_NEK2_1 | 144 | 149 | PF00069 | 0.353 |
| MOD_NEK2_1 | 182 | 187 | PF00069 | 0.339 |
| MOD_NEK2_1 | 216 | 221 | PF00069 | 0.353 |
| MOD_NEK2_1 | 225 | 230 | PF00069 | 0.353 |
| MOD_NEK2_1 | 261 | 266 | PF00069 | 0.372 |
| MOD_NEK2_1 | 304 | 309 | PF00069 | 0.486 |
| MOD_NEK2_1 | 56 | 61 | PF00069 | 0.438 |
| MOD_NEK2_2 | 277 | 282 | PF00069 | 0.428 |
| MOD_NEK2_2 | 297 | 302 | PF00069 | 0.236 |
| MOD_PIKK_1 | 32 | 38 | PF00454 | 0.430 |
| MOD_PIKK_1 | 63 | 69 | PF00454 | 0.427 |
| MOD_PK_1 | 187 | 193 | PF00069 | 0.353 |
| MOD_PKA_1 | 232 | 238 | PF00069 | 0.455 |
| MOD_PKA_2 | 107 | 113 | PF00069 | 0.369 |
| MOD_PKA_2 | 216 | 222 | PF00069 | 0.353 |
| MOD_PKA_2 | 225 | 231 | PF00069 | 0.353 |
| MOD_Plk_1 | 297 | 303 | PF00069 | 0.400 |
| MOD_Plk_4 | 111 | 117 | PF00069 | 0.339 |
| MOD_Plk_4 | 129 | 135 | PF00069 | 0.339 |
| MOD_Plk_4 | 232 | 238 | PF00069 | 0.310 |
| MOD_Plk_4 | 256 | 262 | PF00069 | 0.379 |
| MOD_Plk_4 | 60 | 66 | PF00069 | 0.335 |
| MOD_Plk_4 | 73 | 79 | PF00069 | 0.211 |
| MOD_SUMO_for_1 | 43 | 46 | PF00179 | 0.353 |
| MOD_SUMO_rev_2 | 132 | 140 | PF00179 | 0.342 |
| MOD_SUMO_rev_2 | 228 | 235 | PF00179 | 0.448 |
| TRG_DiLeu_BaEn_2 | 255 | 261 | PF01217 | 0.453 |
| TRG_ENDOCYTIC_2 | 188 | 191 | PF00928 | 0.328 |
| TRG_ENDOCYTIC_2 | 210 | 213 | PF00928 | 0.339 |
| TRG_ENDOCYTIC_2 | 234 | 237 | PF00928 | 0.430 |
| TRG_ENDOCYTIC_2 | 275 | 278 | PF00928 | 0.382 |
| TRG_ENDOCYTIC_2 | 61 | 64 | PF00928 | 0.340 |
| TRG_ER_diArg_1 | 19 | 21 | PF00400 | 0.438 |
| TRG_ER_diArg_1 | 282 | 284 | PF00400 | 0.501 |
| TRG_ER_diLys_1 | 321 | 324 | PF00400 | 0.612 |
| TRG_NLS_MonoExtC_3 | 317 | 322 | PF00514 | 0.527 |
| TRG_Pf-PMV_PEXEL_1 | 265 | 270 | PF00026 | 0.418 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P3F5 | Leptomonas seymouri | 69% | 91% |
| A0A0N1HU44 | Leptomonas seymouri | 75% | 98% |
| A0A0N1HU45 | Leptomonas seymouri | 43% | 84% |
| A0A0N1I2H3 | Leptomonas seymouri | 39% | 88% |
| A0A0N1PC31 | Leptomonas seymouri | 25% | 83% |
| A0A0S4IVY6 | Bodo saltans | 48% | 79% |
| A0A0S4J6L4 | Bodo saltans | 27% | 85% |
| A0A0S4J7K4 | Bodo saltans | 24% | 67% |
| A0A0S4J9Q7 | Bodo saltans | 28% | 72% |
| A0A0S4JA30 | Bodo saltans | 52% | 89% |
| A0A0S4JN06 | Bodo saltans | 63% | 90% |
| A0A0S4JP58 | Bodo saltans | 49% | 76% |
| A0A0S4JU73 | Bodo saltans | 26% | 68% |
| A0A0S4JXJ0 | Bodo saltans | 42% | 100% |
| A0A0S4KMV7 | Bodo saltans | 24% | 100% |
| A0A1X0NIT3 | Trypanosomatidae | 65% | 98% |
| A0A1X0NRZ9 | Trypanosomatidae | 25% | 88% |
| A0A1X0NXJ1 | Trypanosomatidae | 41% | 88% |
| A0A1X0NZS9 | Trypanosomatidae | 50% | 73% |
| A0A1X0P176 | Trypanosomatidae | 47% | 84% |
| A0A3Q8IAQ1 | Leishmania donovani | 21% | 91% |
| A0A3Q8IJ66 | Leishmania donovani | 70% | 92% |
| A0A3Q8INQ4 | Leishmania donovani | 25% | 83% |
| A0A3Q8ISA0 | Leishmania donovani | 47% | 86% |
| A0A3R7K5P9 | Trypanosoma rangeli | 23% | 87% |
| A0A3R7KRP1 | Trypanosoma rangeli | 25% | 68% |
| A0A3S5IRC3 | Trypanosoma rangeli | 24% | 87% |
| A0A3S7WNZ6 | Leishmania donovani | 38% | 88% |
| A0A3S7X8X3 | Leishmania donovani | 90% | 100% |
| A0A422MSV5 | Trypanosoma rangeli | 40% | 89% |
| A0A422N5C9 | Trypanosoma rangeli | 69% | 100% |
| A0A422NL83 | Trypanosoma rangeli | 46% | 82% |
| A0A8I3S724 | Canis lupus familiaris | 25% | 80% |
| A4H436 | Leishmania braziliensis | 37% | 88% |
| A4HCD7 | Leishmania braziliensis | 22% | 76% |
| A4HIT6 | Leishmania braziliensis | 44% | 83% |
| A4HMD0 | Leishmania braziliensis | 77% | 97% |
| A4HMD1 | Leishmania braziliensis | 70% | 92% |
| A4HSC0 | Leishmania infantum | 38% | 88% |
| A4HZW8 | Leishmania infantum | 21% | 91% |
| A4I1T4 | Leishmania infantum | 25% | 83% |
| A4I638 | Leishmania infantum | 47% | 86% |
| A4IAZ7 | Leishmania infantum | 90% | 100% |
| A4IAZ8 | Leishmania infantum | 70% | 92% |
| A4IGM9 | Xenopus tropicalis | 24% | 90% |
| A5GFW1 | Sus scrofa | 25% | 81% |
| A5TY85 | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) | 28% | 75% |
| A7E3X2 | Bos taurus | 51% | 71% |
| A8XJQ6 | Caenorhabditis briggsae | 27% | 84% |
| B9VVJ6 | Trypanosoma brucei brucei | 67% | 98% |
| C9ZK43 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 49% | 81% |
| C9ZN29 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 25% | 67% |
| C9ZNJ6 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 63% | 98% |
| C9ZNJ8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 67% | 98% |
| D0A1R2 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 36% | 85% |
| D0A8X3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 25% | 88% |
| E9AKA2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 38% | 88% |
| E9AXW8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 25% | 83% |
| E9B1C3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 48% | 82% |
| E9B5Y0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 91% | 100% |
| E9B5Y1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 70% | 92% |
| O14965 | Homo sapiens | 25% | 80% |
| O15726 | Plasmodium falciparum (isolate Dd2) | 57% | 100% |
| O55099 | Rattus norvegicus | 24% | 94% |
| O57252 | Vaccinia virus (strain Ankara) | 24% | 100% |
| O57259 | Vaccinia virus (strain Ankara) | 26% | 100% |
| O60145 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 26% | 81% |
| O74135 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 49% | 74% |
| O74426 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 27% | 96% |
| O76324 | Drosophila melanogaster | 59% | 74% |
| O80888 | Arabidopsis thaliana | 24% | 87% |
| O96999 | Leishmania major | 37% | 100% |
| P05986 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 25% | 81% |
| P06244 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 25% | 82% |
| P06245 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 24% | 85% |
| P16913 | Vaccinia virus (strain Western Reserve) | 24% | 100% |
| P20505 | Vaccinia virus (strain Copenhagen) | 24% | 100% |
| P21098 | Vaccinia virus (strain Copenhagen) | 26% | 100% |
| P24362 | Vaccinia virus (strain Western Reserve) | 26% | 100% |
| P33800 | Variola virus (isolate Human/India/Ind3/1967) | 24% | 100% |
| P34516 | Caenorhabditis elegans | 30% | 94% |
| P35507 | Bos taurus | 53% | 96% |
| P35508 | Bos taurus | 61% | 78% |
| P35509 | Bos taurus | 51% | 100% |
| P40233 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 45% | 73% |
| P40234 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 49% | 74% |
| P40235 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 60% | 89% |
| P40236 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 57% | 81% |
| P42158 | Arabidopsis thaliana | 59% | 72% |
| P42168 | Caenorhabditis elegans | 56% | 95% |
| P42169 | Caenorhabditis elegans | 28% | 95% |
| P42818 | Arabidopsis thaliana | 23% | 70% |
| P48729 | Homo sapiens | 55% | 96% |
| P48730 | Homo sapiens | 61% | 78% |
| P49674 | Homo sapiens | 61% | 78% |
| P54367 | Drosophila melanogaster | 55% | 96% |
| P54743 | Mycobacterium leprae (strain TN) | 28% | 74% |
| P59241 | Rattus norvegicus | 25% | 82% |
| P65727 | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) | 28% | 75% |
| P67827 | Bos taurus | 55% | 100% |
| P67828 | Oryctolagus cuniculus | 55% | 100% |
| P67829 | Ovis aries | 55% | 100% |
| P67962 | Gallus gallus | 55% | 96% |
| P67963 | Xenopus laevis | 55% | 96% |
| P78368 | Homo sapiens | 51% | 78% |
| P97477 | Mus musculus | 24% | 82% |
| P97633 | Rattus norvegicus | 54% | 100% |
| P9WI74 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 23% | 68% |
| P9WI75 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 23% | 68% |
| P9WI82 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 28% | 75% |
| P9WI83 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 28% | 75% |
| Q06486 | Rattus norvegicus | 61% | 78% |
| Q07174 | Mus musculus | 24% | 69% |
| Q09503 | Caenorhabditis elegans | 29% | 100% |
| Q2TA06 | Bos taurus | 25% | 81% |
| Q2YDN8 | Bos taurus | 24% | 72% |
| Q32PI1 | Bos taurus | 28% | 82% |
| Q39030 | Arabidopsis thaliana | 22% | 69% |
| Q39050 | Arabidopsis thaliana | 61% | 71% |
| Q4Q6U1 | Leishmania major | 47% | 100% |
| Q4Q9K2 | Leishmania major | 25% | 84% |
| Q4R9A9 | Macaca fascicularis | 52% | 85% |
| Q54L81 | Dictyostelium discoideum | 24% | 70% |
| Q556Y4 | Dictyostelium discoideum | 58% | 76% |
| Q5BP74 | Xenopus laevis | 61% | 78% |
| Q5PRD4 | Danio rerio | 52% | 77% |
| Q5R4V3 | Pongo abelii | 50% | 71% |
| Q5RC72 | Pongo abelii | 61% | 78% |
| Q5XF24 | Arabidopsis thaliana | 62% | 69% |
| Q5ZJS0 | Gallus gallus | 52% | 71% |
| Q5ZLL1 | Gallus gallus | 61% | 78% |
| Q62761 | Rattus norvegicus | 51% | 83% |
| Q62762 | Rattus norvegicus | 51% | 78% |
| Q62763 | Rattus norvegicus | 51% | 72% |
| Q6CWQ4 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 24% | 90% |
| Q6DE08 | Xenopus laevis | 24% | 90% |
| Q6DE87 | Xenopus laevis | 27% | 68% |
| Q6GPL3 | Xenopus laevis | 24% | 88% |
| Q6K9N1 | Oryza sativa subsp. japonica | 61% | 70% |
| Q6NRT0 | Xenopus laevis | 52% | 70% |
| Q6NW76 | Danio rerio | 25% | 100% |
| Q6P3K7 | Danio rerio | 61% | 79% |
| Q6P647 | Xenopus tropicalis | 61% | 78% |
| Q6QNL9 | Eimeria tenella | 62% | 97% |
| Q6QNM1 | Toxoplasma gondii | 59% | 100% |
| Q7JP68 | Caenorhabditis elegans | 27% | 81% |
| Q7RBX5 | Plasmodium yoelii yoelii | 58% | 100% |
| Q7T2E3 | Danio rerio | 62% | 80% |
| Q7TZN1 | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) | 23% | 68% |
| Q7YRC6 | Bos taurus | 24% | 94% |
| Q7ZUS1 | Danio rerio | 27% | 76% |
| Q80X41 | Mus musculus | 27% | 74% |
| Q8BK63 | Mus musculus | 55% | 96% |
| Q8BTH8 | Mus musculus | 51% | 71% |
| Q8BVP5 | Mus musculus | 51% | 78% |
| Q8C4X2 | Mus musculus | 51% | 76% |
| Q8IHZ9 | Plasmodium falciparum (isolate 3D7) | 58% | 100% |
| Q8IV63 | Homo sapiens | 24% | 68% |
| Q8K3G5 | Mus musculus | 24% | 72% |
| Q8LG64 | Arabidopsis thaliana | 24% | 100% |
| Q8LPI7 | Arabidopsis thaliana | 56% | 78% |
| Q8LPJ1 | Arabidopsis thaliana | 56% | 68% |
| Q8N752 | Homo sapiens | 58% | 96% |
| Q8NU97 | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) | 26% | 69% |
| Q8SQR2 | Encephalitozoon cuniculi (strain GB-M1) | 33% | 100% |
| Q8SRK8 | Encephalitozoon cuniculi (strain GB-M1) | 26% | 100% |
| Q8SRL5 | Encephalitozoon cuniculi (strain GB-M1) | 23% | 100% |
| Q8SS96 | Encephalitozoon cuniculi (strain GB-M1) | 45% | 100% |
| Q8VYK9 | Arabidopsis thaliana | 59% | 74% |
| Q8WQ99 | Caenorhabditis elegans | 49% | 80% |
| Q8WU08 | Homo sapiens | 25% | 82% |
| Q91819 | Xenopus laevis | 26% | 79% |
| Q91820 | Xenopus laevis | 26% | 80% |
| Q91FD5 | Invertebrate iridescent virus 6 | 25% | 79% |
| Q925K9 | Mus musculus | 24% | 100% |
| Q93Z18 | Arabidopsis thaliana | 56% | 78% |
| Q95PZ9 | Caenorhabditis elegans | 30% | 85% |
| Q99986 | Homo sapiens | 28% | 82% |
| Q9BXA6 | Homo sapiens | 23% | 100% |
| Q9CAI5 | Arabidopsis thaliana | 61% | 70% |
| Q9DC28 | Mus musculus | 61% | 78% |
| Q9FFH8 | Arabidopsis thaliana | 61% | 68% |
| Q9GM70 | Oryctolagus cuniculus | 24% | 82% |
| Q9HCP0 | Homo sapiens | 52% | 77% |
| Q9J509 | Fowlpox virus (strain NVSL) | 23% | 100% |
| Q9J523 | Fowlpox virus (strain NVSL) | 26% | 100% |
| Q9JMK2 | Mus musculus | 61% | 78% |
| Q9LSX4 | Arabidopsis thaliana | 62% | 68% |
| Q9LW62 | Arabidopsis thaliana | 61% | 73% |
| Q9M077 | Arabidopsis thaliana | 23% | 100% |
| Q9N0X0 | Sus scrofa | 26% | 94% |
| Q9NHE1 | Leishmania major | 68% | 100% |
| Q9STV4 | Arabidopsis thaliana | 27% | 73% |
| Q9UQB9 | Homo sapiens | 27% | 100% |
| Q9Y6M4 | Homo sapiens | 50% | 72% |
| Q9ZUP4 | Arabidopsis thaliana | 61% | 75% |
| Q9ZWB3 | Arabidopsis thaliana | 61% | 69% |
| V5AIW9 | Trypanosoma cruzi | 41% | 88% |
| V5BC61 | Trypanosoma cruzi | 27% | 100% |
| V5BFI8 | Trypanosoma cruzi | 27% | 73% |
| V5BMQ3 | Trypanosoma cruzi | 47% | 81% |
| V5BP88 | Trypanosoma cruzi | 24% | 70% |
| V5BQF4 | Trypanosoma cruzi | 24% | 87% |