Nucleolin_bd domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9NF96_LEIMA

TriTrypDb:

LmjF.04.0990 , LMJLV39_040015600 , LMJSD75_040015900

Length:

444

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9NF96

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9NF96

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	259	263	PF00656	0.802
CLV_C14_Caspase3-7	307	311	PF00656	0.644
CLV_NRD_NRD_1	119	121	PF00675	0.540
CLV_NRD_NRD_1	340	342	PF00675	0.685
CLV_NRD_NRD_1	406	408	PF00675	0.705
CLV_PCSK_FUR_1	117	121	PF00082	0.541
CLV_PCSK_FUR_1	387	391	PF00082	0.430
CLV_PCSK_KEX2_1	117	119	PF00082	0.541
CLV_PCSK_KEX2_1	384	386	PF00082	0.699
CLV_PCSK_KEX2_1	389	391	PF00082	0.618
CLV_PCSK_KEX2_1	406	408	PF00082	0.643
CLV_PCSK_PC1ET2_1	384	386	PF00082	0.699
CLV_PCSK_PC1ET2_1	389	391	PF00082	0.618
CLV_PCSK_PC7_1	113	119	PF00082	0.545
CLV_PCSK_PC7_1	385	391	PF00082	0.423
CLV_PCSK_SKI1_1	119	123	PF00082	0.540
CLV_PCSK_SKI1_1	228	232	PF00082	0.461
CLV_PCSK_SKI1_1	361	365	PF00082	0.401
CLV_Separin_Metazoa	171	175	PF03568	0.669
DEG_Nend_UBRbox_1	1	4	PF02207	0.599
DOC_MAPK_gen_1	117	124	PF00069	0.542
DOC_MAPK_gen_1	384	394	PF00069	0.705
DOC_MAPK_HePTP_8	165	177	PF00069	0.670
DOC_MAPK_MEF2A_6	168	177	PF00069	0.664
DOC_MAPK_MEF2A_6	361	368	PF00069	0.396
DOC_PP1_RVXF_1	118	125	PF00149	0.541
DOC_PP2B_LxvP_1	33	36	PF13499	0.513
DOC_PP2B_LxvP_1	48	51	PF13499	0.499
DOC_USP7_MATH_1	102	106	PF00917	0.722
DOC_USP7_MATH_1	11	15	PF00917	0.571
DOC_USP7_MATH_1	158	162	PF00917	0.511
DOC_USP7_MATH_1	272	276	PF00917	0.610
DOC_USP7_MATH_1	29	33	PF00917	0.517
DOC_USP7_MATH_1	321	325	PF00917	0.593
DOC_USP7_MATH_1	352	356	PF00917	0.720
DOC_USP7_MATH_1	418	422	PF00917	0.867
DOC_USP7_MATH_1	427	431	PF00917	0.703
DOC_USP7_UBL2_3	380	384	PF12436	0.704
DOC_WW_Pin1_4	132	137	PF00397	0.509
DOC_WW_Pin1_4	154	159	PF00397	0.539
DOC_WW_Pin1_4	3	8	PF00397	0.596
DOC_WW_Pin1_4	423	428	PF00397	0.696
DOC_WW_Pin1_4	95	100	PF00397	0.590
LIG_14-3-3_CanoR_1	119	125	PF00244	0.541
LIG_14-3-3_CanoR_1	12	19	PF00244	0.635
LIG_14-3-3_CanoR_1	341	346	PF00244	0.707
LIG_14-3-3_CanoR_1	435	440	PF00244	0.839
LIG_BRCT_BRCA1_1	68	72	PF00533	0.524
LIG_Clathr_ClatBox_1	365	369	PF01394	0.399
LIG_eIF4E_1	359	365	PF01652	0.390
LIG_EVH1_1	48	52	PF00568	0.551
LIG_FHA_1	168	174	PF00498	0.666
LIG_FHA_2	200	206	PF00498	0.533
LIG_FHA_2	349	355	PF00498	0.568
LIG_Integrin_RGD_1	2	4	PF01839	0.595
LIG_IRF3_LxIS_1	128	135	PF10401	0.525
LIG_LIR_Gen_1	20	29	PF02991	0.521
LIG_LIR_Gen_1	362	368	PF02991	0.421
LIG_LIR_Gen_1	69	80	PF02991	0.511
LIG_LIR_Nem_3	20	25	PF02991	0.628
LIG_LIR_Nem_3	362	366	PF02991	0.392
LIG_LIR_Nem_3	69	75	PF02991	0.517
LIG_NRBOX	168	174	PF00104	0.666
LIG_SH2_CRK	112	116	PF00017	0.553
LIG_SH2_SRC	207	210	PF00017	0.395
LIG_SH2_STAP1	38	42	PF00017	0.540
LIG_SH2_STAT5	207	210	PF00017	0.643
LIG_SH2_STAT5	22	25	PF00017	0.525
LIG_SH2_STAT5	359	362	PF00017	0.680
LIG_SH2_STAT5	38	41	PF00017	0.486
LIG_SH3_3	344	350	PF00018	0.716
LIG_SH3_3	46	52	PF00018	0.552
LIG_SH3_3	96	102	PF00018	0.572
LIG_SUMO_SIM_anti_2	391	396	PF11976	0.706
LIG_SUMO_SIM_par_1	130	135	PF11976	0.525
LIG_SUMO_SIM_par_1	138	143	PF11976	0.526
LIG_TRAF2_1	351	354	PF00917	0.730
LIG_TYR_ITIM	110	115	PF00017	0.564
LIG_WRC_WIRS_1	121	126	PF05994	0.542
MOD_CK1_1	135	141	PF00069	0.511
MOD_CK1_1	250	256	PF00069	0.881
MOD_CK1_1	41	47	PF00069	0.546
MOD_CK1_1	423	429	PF00069	0.674
MOD_CK1_1	430	436	PF00069	0.552
MOD_CK1_1	6	12	PF00069	0.617
MOD_CK2_1	11	17	PF00069	0.561
MOD_CK2_1	199	205	PF00069	0.701
MOD_CK2_1	272	278	PF00069	0.607
MOD_CK2_1	348	354	PF00069	0.572
MOD_GlcNHglycan	105	108	PF01048	0.570
MOD_GlcNHglycan	211	214	PF01048	0.395
MOD_GlcNHglycan	324	327	PF01048	0.850
MOD_GlcNHglycan	33	36	PF01048	0.513
MOD_GlcNHglycan	40	43	PF01048	0.512
MOD_GlcNHglycan	420	423	PF01048	0.753
MOD_GlcNHglycan	429	432	PF01048	0.813
MOD_GSK3_1	138	145	PF00069	0.499
MOD_GSK3_1	154	161	PF00069	0.455
MOD_GSK3_1	209	216	PF00069	0.391
MOD_GSK3_1	348	355	PF00069	0.552
MOD_GSK3_1	37	44	PF00069	0.554
MOD_GSK3_1	423	430	PF00069	0.825
MOD_GSK3_1	56	63	PF00069	0.511
MOD_GSK3_1	6	13	PF00069	0.594
MOD_GSK3_1	81	88	PF00069	0.550
MOD_LATS_1	346	352	PF00433	0.445
MOD_LATS_1	54	60	PF00433	0.581
MOD_N-GLC_1	182	187	PF02516	0.711
MOD_N-GLC_1	250	255	PF02516	0.601
MOD_N-GLC_1	81	86	PF02516	0.531
MOD_NEK2_1	111	116	PF00069	0.556
MOD_NEK2_1	140	145	PF00069	0.506
MOD_NEK2_1	60	65	PF00069	0.559
MOD_PIKK_1	100	106	PF00454	0.516
MOD_PIKK_1	11	17	PF00454	0.561
MOD_PIKK_1	420	426	PF00454	0.598
MOD_PIKK_1	87	93	PF00454	0.596
MOD_PK_1	300	306	PF00069	0.601
MOD_PKA_1	300	306	PF00069	0.867
MOD_PKA_1	341	347	PF00069	0.703
MOD_PKA_2	11	17	PF00069	0.561
MOD_PKA_2	66	72	PF00069	0.522
MOD_PKB_1	118	126	PF00069	0.542
MOD_Plk_1	17	23	PF00069	0.555
MOD_Plk_1	182	188	PF00069	0.704
MOD_Plk_1	352	358	PF00069	0.713
MOD_Plk_2-3	255	261	PF00069	0.878
MOD_Plk_2-3	270	276	PF00069	0.631
MOD_Plk_2-3	279	285	PF00069	0.845
MOD_Plk_4	135	141	PF00069	0.503
MOD_Plk_4	17	23	PF00069	0.555
MOD_Plk_4	215	221	PF00069	0.453
MOD_Plk_4	435	441	PF00069	0.836
MOD_ProDKin_1	132	138	PF00069	0.507
MOD_ProDKin_1	154	160	PF00069	0.532
MOD_ProDKin_1	3	9	PF00069	0.596
MOD_ProDKin_1	423	429	PF00069	0.694
MOD_ProDKin_1	95	101	PF00069	0.585
MOD_SUMO_for_1	388	391	PF00179	0.427
MOD_SUMO_rev_2	160	170	PF00179	0.710
TRG_DiLeu_BaEn_3	307	313	PF01217	0.589
TRG_ENDOCYTIC_2	112	115	PF00928	0.566
TRG_ENDOCYTIC_2	22	25	PF00928	0.630
TRG_ER_diArg_1	117	120	PF00400	0.540
TRG_ER_diArg_1	406	409	PF00400	0.649
TRG_NES_CRM1_1	354	369	PF08389	0.400
TRG_NLS_MonoExtN_4	299	304	PF00514	0.882

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H414	Leishmania braziliensis	69%	100%