Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

Q9NF89_LEIMA

TriTrypDb:

LmjF.04.1060 , LMJLV39_040016200 , LMJSD75_040016500

Length:

485

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9NF89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9NF89

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	174	176	PF00675	0.636
CLV_NRD_NRD_1	278	280	PF00675	0.639
CLV_NRD_NRD_1	465	467	PF00675	0.738
CLV_PCSK_KEX2_1	174	176	PF00082	0.636
CLV_PCSK_KEX2_1	194	196	PF00082	0.497
CLV_PCSK_KEX2_1	278	280	PF00082	0.524
CLV_PCSK_KEX2_1	465	467	PF00082	0.738
CLV_PCSK_KEX2_1	85	87	PF00082	0.637
CLV_PCSK_PC1ET2_1	194	196	PF00082	0.640
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.637
CLV_PCSK_SKI1_1	194	198	PF00082	0.637
CLV_PCSK_SKI1_1	303	307	PF00082	0.692
DEG_APCC_DBOX_1	277	285	PF00400	0.639
DEG_Kelch_Keap1_1	389	394	PF01344	0.620
DEG_SCF_FBW7_1	109	116	PF00400	0.648
DEG_SCF_FBW7_1	235	241	PF00400	0.751
DEG_SPOP_SBC_1	305	309	PF00917	0.639
DOC_CKS1_1	110	115	PF01111	0.651
DOC_CKS1_1	200	205	PF01111	0.637
DOC_CKS1_1	219	224	PF01111	0.544
DOC_CKS1_1	235	240	PF01111	0.677
DOC_MAPK_gen_1	49	58	PF00069	0.622
DOC_MAPK_HePTP_8	46	58	PF00069	0.635
DOC_MAPK_MEF2A_6	49	58	PF00069	0.622
DOC_MAPK_NFAT4_5	51	59	PF00069	0.628
DOC_PP2B_LxvP_1	153	156	PF13499	0.606
DOC_USP7_MATH_1	113	117	PF00917	0.657
DOC_USP7_MATH_1	126	130	PF00917	0.511
DOC_USP7_MATH_1	143	147	PF00917	0.560
DOC_USP7_MATH_1	184	188	PF00917	0.797
DOC_USP7_MATH_1	238	242	PF00917	0.708
DOC_USP7_MATH_1	327	331	PF00917	0.646
DOC_USP7_MATH_1	352	356	PF00917	0.708
DOC_USP7_MATH_1	370	374	PF00917	0.766
DOC_USP7_MATH_1	8	12	PF00917	0.822
DOC_WW_Pin1_4	109	114	PF00397	0.649
DOC_WW_Pin1_4	12	17	PF00397	0.617
DOC_WW_Pin1_4	161	166	PF00397	0.565
DOC_WW_Pin1_4	199	204	PF00397	0.670
DOC_WW_Pin1_4	218	223	PF00397	0.681
DOC_WW_Pin1_4	234	239	PF00397	0.609
DOC_WW_Pin1_4	246	251	PF00397	0.633
DOC_WW_Pin1_4	257	262	PF00397	0.622
DOC_WW_Pin1_4	306	311	PF00397	0.729
DOC_WW_Pin1_4	332	337	PF00397	0.827
DOC_WW_Pin1_4	4	9	PF00397	0.822
DOC_WW_Pin1_4	405	410	PF00397	0.589
DOC_WW_Pin1_4	56	61	PF00397	0.670
LIG_14-3-3_CanoR_1	178	183	PF00244	0.633
LIG_14-3-3_CanoR_1	303	312	PF00244	0.738
LIG_14-3-3_CanoR_1	465	472	PF00244	0.775
LIG_Actin_WH2_2	41	59	PF00022	0.514
LIG_APCC_ABBA_1	447	452	PF00400	0.741
LIG_BIR_II_1	1	5	PF00653	0.828
LIG_BRCT_BRCA1_1	14	18	PF00533	0.694
LIG_BRCT_BRCA1_1	148	152	PF00533	0.625
LIG_BRCT_BRCA1_1	410	414	PF00533	0.752
LIG_BRCT_BRCA1_1	73	77	PF00533	0.585
LIG_FHA_1	191	197	PF00498	0.635
LIG_FHA_1	283	289	PF00498	0.647
LIG_FHA_1	307	313	PF00498	0.765
LIG_FHA_1	333	339	PF00498	0.626
LIG_FHA_2	17	23	PF00498	0.692
LIG_FHA_2	266	272	PF00498	0.778
LIG_FHA_2	438	444	PF00498	0.766
LIG_Integrin_RGDW_4	197	200	PF00362	0.593
LIG_LIR_Apic_2	199	203	PF02991	0.634
LIG_LIR_Gen_1	149	157	PF02991	0.618
LIG_LIR_Gen_1	167	176	PF02991	0.341
LIG_LIR_Nem_3	103	109	PF02991	0.707
LIG_LIR_Nem_3	149	155	PF02991	0.632
LIG_LIR_Nem_3	167	172	PF02991	0.317
LIG_LYPXL_yS_3	106	109	PF13949	0.660
LIG_NRBOX	29	35	PF00104	0.622
LIG_PCNA_yPIPBox_3	21	34	PF02747	0.638
LIG_Pex14_2	77	81	PF04695	0.610
LIG_PTAP_UEV_1	202	207	PF05743	0.602
LIG_SH2_STAT5	23	26	PF00017	0.647
LIG_SH3_3	104	110	PF00018	0.685
LIG_SH3_3	200	206	PF00018	0.675
LIG_SH3_3	216	222	PF00018	0.575
LIG_SH3_3	250	256	PF00018	0.806
LIG_SH3_3	342	348	PF00018	0.767
LIG_SH3_3	420	426	PF00018	0.828
LIG_SH3_3	475	481	PF00018	0.840
LIG_SUMO_SIM_par_1	229	237	PF11976	0.612
LIG_SUMO_SIM_par_1	248	254	PF11976	0.500
LIG_TRAF2_1	341	344	PF00917	0.842
LIG_WW_3	182	186	PF00397	0.727
MOD_CDK_SPK_2	56	61	PF00069	0.608
MOD_CK1_1	146	152	PF00069	0.646
MOD_CK1_1	2	8	PF00069	0.823
MOD_CK1_1	249	255	PF00069	0.708
MOD_CK1_1	311	317	PF00069	0.653
MOD_CK1_1	322	328	PF00069	0.688
MOD_CK1_1	408	414	PF00069	0.736
MOD_CK1_1	417	423	PF00069	0.690
MOD_CK1_1	459	465	PF00069	0.830
MOD_CK1_1	467	473	PF00069	0.706
MOD_CK1_1	474	480	PF00069	0.597
MOD_CK1_1	76	82	PF00069	0.727
MOD_CK2_1	388	394	PF00069	0.783
MOD_GlcNHglycan	128	131	PF01048	0.514
MOD_GlcNHglycan	145	148	PF01048	0.554
MOD_GlcNHglycan	166	169	PF01048	0.607
MOD_GlcNHglycan	180	183	PF01048	0.492
MOD_GlcNHglycan	186	189	PF01048	0.645
MOD_GlcNHglycan	203	206	PF01048	0.548
MOD_GlcNHglycan	222	225	PF01048	0.614
MOD_GlcNHglycan	3	7	PF01048	0.821
MOD_GlcNHglycan	313	316	PF01048	0.675
MOD_GlcNHglycan	324	327	PF01048	0.754
MOD_GlcNHglycan	355	358	PF01048	0.831
MOD_GlcNHglycan	381	384	PF01048	0.756
MOD_GlcNHglycan	391	394	PF01048	0.623
MOD_GlcNHglycan	410	413	PF01048	0.530
MOD_GlcNHglycan	418	422	PF01048	0.735
MOD_GlcNHglycan	427	430	PF01048	0.568
MOD_GlcNHglycan	473	476	PF01048	0.808
MOD_GlcNHglycan	99	102	PF01048	0.702
MOD_GSK3_1	109	116	PF00069	0.648
MOD_GSK3_1	12	19	PF00069	0.559
MOD_GSK3_1	164	171	PF00069	0.626
MOD_GSK3_1	2	9	PF00069	0.823
MOD_GSK3_1	234	241	PF00069	0.758
MOD_GSK3_1	245	252	PF00069	0.615
MOD_GSK3_1	304	311	PF00069	0.613
MOD_GSK3_1	328	335	PF00069	0.817
MOD_GSK3_1	433	440	PF00069	0.791
MOD_GSK3_1	455	462	PF00069	0.801
MOD_GSK3_1	464	471	PF00069	0.688
MOD_GSK3_1	76	83	PF00069	0.727
MOD_N-GLC_1	322	327	PF02516	0.604
MOD_N-GLC_1	379	384	PF02516	0.613
MOD_NEK2_1	33	38	PF00069	0.625
MOD_NEK2_1	97	102	PF00069	0.584
MOD_NEK2_2	16	21	PF00069	0.612
MOD_PIKK_1	33	39	PF00454	0.619
MOD_PKA_1	465	471	PF00069	0.734
MOD_PKA_2	177	183	PF00069	0.680
MOD_PKA_2	184	190	PF00069	0.702
MOD_PKA_2	282	288	PF00069	0.645
MOD_PKA_2	464	470	PF00069	0.772
MOD_Plk_1	16	22	PF00069	0.644
MOD_Plk_2-3	371	377	PF00069	0.845
MOD_Plk_2-3	73	79	PF00069	0.715
MOD_Plk_4	148	154	PF00069	0.608
MOD_Plk_4	168	174	PF00069	0.315
MOD_Plk_4	265	271	PF00069	0.576
MOD_ProDKin_1	109	115	PF00069	0.645
MOD_ProDKin_1	12	18	PF00069	0.604
MOD_ProDKin_1	161	167	PF00069	0.563
MOD_ProDKin_1	199	205	PF00069	0.671
MOD_ProDKin_1	218	224	PF00069	0.679
MOD_ProDKin_1	234	240	PF00069	0.602
MOD_ProDKin_1	246	252	PF00069	0.633
MOD_ProDKin_1	257	263	PF00069	0.622
MOD_ProDKin_1	306	312	PF00069	0.735
MOD_ProDKin_1	332	338	PF00069	0.830
MOD_ProDKin_1	4	10	PF00069	0.822
MOD_ProDKin_1	405	411	PF00069	0.588
MOD_ProDKin_1	56	62	PF00069	0.664
MOD_SUMO_rev_2	294	300	PF00179	0.714
TRG_ENDOCYTIC_2	106	109	PF00928	0.660
TRG_ENDOCYTIC_2	450	453	PF00928	0.741
TRG_ER_diArg_1	131	134	PF00400	0.525
TRG_ER_diArg_1	173	175	PF00400	0.629
TRG_ER_diArg_1	288	291	PF00400	0.666
TRG_ER_diArg_1	50	53	PF00400	0.615
TRG_ER_diArg_1	54	57	PF00400	0.550
TRG_NLS_MonoExtC_3	193	199	PF00514	0.635
TRG_Pf-PMV_PEXEL_1	28	32	PF00026	0.625

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WNX2	Leishmania donovani	90%	100%
A4H421	Leishmania braziliensis	63%	100%
A4HSA3	Leishmania infantum	90%	100%
E9AK87	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%