Ubiquitin activating enzyme

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin-activating enzyme E1, putative

Species:

Leishmania major

UniProt:

Q9NF77_LEIMA

TriTrypDb:

LmjF.23.0550 , LMJLV39_230013500 , LMJSD75_230013800

Length:

1044

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 6

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q9NF77

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9NF77

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	2
GO:0006511	ubiquitin-dependent protein catabolic process	7	2
GO:0006807	nitrogen compound metabolic process	2	11
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0008152	metabolic process	1	11
GO:0009056	catabolic process	2	2
GO:0009057	macromolecule catabolic process	4	2
GO:0009987	cellular process	1	2
GO:0016567	protein ubiquitination	7	11
GO:0019538	protein metabolic process	3	11
GO:0019941	modification-dependent protein catabolic process	6	2
GO:0032446	protein modification by small protein conjugation	6	11
GO:0033554	cellular response to stress	3	2
GO:0036211	protein modification process	4	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043412	macromolecule modification	4	11
GO:0043632	modification-dependent macromolecule catabolic process	5	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	11
GO:0044248	cellular catabolic process	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0044265	obsolete cellular macromolecule catabolic process	4	2
GO:0050896	response to stimulus	1	2
GO:0051603	proteolysis involved in protein catabolic process	5	2
GO:0051716	cellular response to stimulus	2	2
GO:0070647	protein modification by small protein conjugation or removal	5	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11
GO:1901575	organic substance catabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003824	catalytic activity	1	12
GO:0004839	ubiquitin activating enzyme activity	3	2
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0008641	ubiquitin-like modifier activating enzyme activity	2	12
GO:0016874	ligase activity	2	12
GO:0016877	ligase activity, forming carbon-sulfur bonds	3	12
GO:0017076	purine nucleotide binding	4	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140096	catalytic activity, acting on a protein	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8
GO:0004842	ubiquitin-protein transferase activity	4	1
GO:0016740	transferase activity	2	1
GO:0016746	acyltransferase activity	3	1
GO:0019787	ubiquitin-like protein transferase activity	3	1
GO:0061631	ubiquitin conjugating enzyme activity	5	1
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	277	281	PF00656	0.322
CLV_NRD_NRD_1	268	270	PF00675	0.401
CLV_NRD_NRD_1	544	546	PF00675	0.302
CLV_NRD_NRD_1	801	803	PF00675	0.291
CLV_NRD_NRD_1	879	881	PF00675	0.599
CLV_PCSK_KEX2_1	268	270	PF00082	0.338
CLV_PCSK_KEX2_1	696	698	PF00082	0.277
CLV_PCSK_KEX2_1	8	10	PF00082	0.434
CLV_PCSK_KEX2_1	801	803	PF00082	0.291
CLV_PCSK_KEX2_1	843	845	PF00082	0.316
CLV_PCSK_KEX2_1	999	1001	PF00082	0.313
CLV_PCSK_PC1ET2_1	696	698	PF00082	0.277
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.478
CLV_PCSK_PC1ET2_1	843	845	PF00082	0.335
CLV_PCSK_PC1ET2_1	999	1001	PF00082	0.313
CLV_PCSK_SKI1_1	340	344	PF00082	0.335
CLV_PCSK_SKI1_1	385	389	PF00082	0.316
CLV_PCSK_SKI1_1	479	483	PF00082	0.301
CLV_PCSK_SKI1_1	54	58	PF00082	0.373
CLV_PCSK_SKI1_1	551	555	PF00082	0.306
CLV_PCSK_SKI1_1	557	561	PF00082	0.300
CLV_PCSK_SKI1_1	613	617	PF00082	0.377
CLV_PCSK_SKI1_1	686	690	PF00082	0.291
CLV_PCSK_SKI1_1	785	789	PF00082	0.386
CLV_PCSK_SKI1_1	870	874	PF00082	0.316
CLV_PCSK_SKI1_1	904	908	PF00082	0.430
CLV_PCSK_SKI1_1	910	914	PF00082	0.332
CLV_PCSK_SKI1_1	956	960	PF00082	0.309
DEG_APCC_DBOX_1	685	693	PF00400	0.477
DEG_Nend_Nbox_1	1	3	PF02207	0.637
DEG_SPOP_SBC_1	123	127	PF00917	0.366
DEG_SPOP_SBC_1	854	858	PF00917	0.360
DOC_CKS1_1	218	223	PF01111	0.322
DOC_CKS1_1	711	716	PF01111	0.475
DOC_CYCLIN_RxL_1	551	564	PF00134	0.303
DOC_CYCLIN_yCln2_LP_2	110	116	PF00134	0.344
DOC_CYCLIN_yCln2_LP_2	631	637	PF00134	0.509
DOC_MAPK_gen_1	133	142	PF00069	0.323
DOC_MAPK_gen_1	828	836	PF00069	0.548
DOC_MAPK_HePTP_8	565	577	PF00069	0.447
DOC_MAPK_MEF2A_6	568	577	PF00069	0.447
DOC_MAPK_MEF2A_6	910	918	PF00069	0.328
DOC_MAPK_MEF2A_6	970	977	PF00069	0.477
DOC_PP1_RVXF_1	137	143	PF00149	0.366
DOC_PP1_RVXF_1	199	205	PF00149	0.447
DOC_PP1_RVXF_1	938	945	PF00149	0.548
DOC_PP2B_LxvP_1	110	113	PF13499	0.344
DOC_PP4_FxxP_1	74	77	PF00568	0.335
DOC_PP4_FxxP_1	923	926	PF00568	0.345
DOC_USP7_MATH_1	123	127	PF00917	0.366
DOC_USP7_MATH_1	179	183	PF00917	0.300
DOC_USP7_MATH_1	219	223	PF00917	0.365
DOC_USP7_MATH_1	415	419	PF00917	0.432
DOC_USP7_MATH_1	930	934	PF00917	0.427
DOC_USP7_MATH_1	935	939	PF00917	0.456
DOC_USP7_UBL2_3	993	997	PF12436	0.496
DOC_WW_Pin1_4	217	222	PF00397	0.380
DOC_WW_Pin1_4	231	236	PF00397	0.273
DOC_WW_Pin1_4	313	318	PF00397	0.360
DOC_WW_Pin1_4	371	376	PF00397	0.301
DOC_WW_Pin1_4	710	715	PF00397	0.462
LIG_14-3-3_CanoR_1	490	495	PF00244	0.447
LIG_14-3-3_CanoR_1	785	790	PF00244	0.436
LIG_Actin_WH2_2	225	243	PF00022	0.366
LIG_AP2alpha_1	681	685	PF02296	0.491
LIG_APCC_ABBA_1	186	191	PF00400	0.316
LIG_BRCT_BRCA1_1	369	373	PF00533	0.301
LIG_BRCT_BRCA1_1	477	481	PF00533	0.301
LIG_Clathr_ClatBox_1	285	289	PF01394	0.478
LIG_Clathr_ClatBox_1	863	867	PF01394	0.316
LIG_eIF4E_1	729	735	PF01652	0.477
LIG_FHA_1	1022	1028	PF00498	0.491
LIG_FHA_1	123	129	PF00498	0.309
LIG_FHA_1	172	178	PF00498	0.505
LIG_FHA_1	235	241	PF00498	0.467
LIG_FHA_1	28	34	PF00498	0.316
LIG_FHA_1	518	524	PF00498	0.325
LIG_FHA_1	723	729	PF00498	0.557
LIG_FHA_1	749	755	PF00498	0.545
LIG_FHA_1	840	846	PF00498	0.467
LIG_FHA_1	854	860	PF00498	0.301
LIG_FHA_2	165	171	PF00498	0.343
LIG_FHA_2	185	191	PF00498	0.224
LIG_FHA_2	272	278	PF00498	0.404
LIG_FHA_2	465	471	PF00498	0.303
LIG_FHA_2	508	514	PF00498	0.366
LIG_FHA_2	63	69	PF00498	0.367
LIG_FHA_2	711	717	PF00498	0.475
LIG_FHA_2	757	763	PF00498	0.543
LIG_GBD_Chelix_1	959	967	PF00786	0.282
LIG_LIR_Apic_2	583	589	PF02991	0.360
LIG_LIR_Apic_2	71	77	PF02991	0.335
LIG_LIR_Apic_2	931	937	PF02991	0.443
LIG_LIR_Gen_1	1017	1027	PF02991	0.570
LIG_LIR_Gen_1	614	624	PF02991	0.467
LIG_LIR_Gen_1	911	921	PF02991	0.372
LIG_LIR_LC3C_4	1020	1023	PF02991	0.570
LIG_LIR_LC3C_4	30	35	PF02991	0.316
LIG_LIR_Nem_3	1017	1022	PF02991	0.570
LIG_LIR_Nem_3	222	227	PF02991	0.447
LIG_LIR_Nem_3	270	275	PF02991	0.385
LIG_LIR_Nem_3	370	376	PF02991	0.301
LIG_LIR_Nem_3	614	619	PF02991	0.467
LIG_LIR_Nem_3	683	688	PF02991	0.483
LIG_LIR_Nem_3	911	916	PF02991	0.371
LIG_NRBOX	614	620	PF00104	0.570
LIG_NRBOX	671	677	PF00104	0.564
LIG_NRBOX	868	874	PF00104	0.316
LIG_NRBOX	962	968	PF00104	0.534
LIG_PDZ_Class_2	1039	1044	PF00595	0.469
LIG_Pex14_2	524	528	PF04695	0.301
LIG_Pex14_2	616	620	PF04695	0.467
LIG_Pex14_2	681	685	PF04695	0.471
LIG_Pex14_2	909	913	PF04695	0.475
LIG_PTB_Apo_2	522	529	PF02174	0.335
LIG_REV1ctd_RIR_1	71	76	PF16727	0.344
LIG_SH2_CRK	272	276	PF00017	0.344
LIG_SH2_CRK	555	559	PF00017	0.335
LIG_SH2_CRK	739	743	PF00017	0.509
LIG_SH2_CRK	832	836	PF00017	0.467
LIG_SH2_CRK	934	938	PF00017	0.461
LIG_SH2_GRB2like	120	123	PF00017	0.447
LIG_SH2_GRB2like	630	633	PF00017	0.466
LIG_SH2_NCK_1	120	124	PF00017	0.366
LIG_SH2_NCK_1	294	298	PF00017	0.257
LIG_SH2_NCK_1	586	590	PF00017	0.360
LIG_SH2_NCK_1	934	938	PF00017	0.541
LIG_SH2_SRC	547	550	PF00017	0.316
LIG_SH2_SRC	586	589	PF00017	0.360
LIG_SH2_SRC	677	680	PF00017	0.570
LIG_SH2_SRC	895	898	PF00017	0.653
LIG_SH2_STAP1	120	124	PF00017	0.447
LIG_SH2_STAP1	512	516	PF00017	0.428
LIG_SH2_STAP1	582	586	PF00017	0.335
LIG_SH2_STAP1	971	975	PF00017	0.570
LIG_SH2_STAT3	12	15	PF00017	0.316
LIG_SH2_STAT3	420	423	PF00017	0.316
LIG_SH2_STAT3	434	437	PF00017	0.316
LIG_SH2_STAT5	1018	1021	PF00017	0.570
LIG_SH2_STAT5	120	123	PF00017	0.447
LIG_SH2_STAT5	124	127	PF00017	0.447
LIG_SH2_STAT5	17	20	PF00017	0.316
LIG_SH2_STAT5	203	206	PF00017	0.395
LIG_SH2_STAT5	260	263	PF00017	0.301
LIG_SH2_STAT5	294	297	PF00017	0.235
LIG_SH2_STAT5	434	437	PF00017	0.335
LIG_SH2_STAT5	547	550	PF00017	0.301
LIG_SH2_STAT5	630	633	PF00017	0.467
LIG_SH2_STAT5	823	826	PF00017	0.469
LIG_SH2_STAT5	871	874	PF00017	0.335
LIG_SH2_STAT5	895	898	PF00017	0.625
LIG_SH2_STAT5	987	990	PF00017	0.570
LIG_SH3_3	1030	1036	PF00018	0.480
LIG_SH3_3	215	221	PF00018	0.381
LIG_SH3_3	229	235	PF00018	0.301
LIG_SH3_3	311	317	PF00018	0.447
LIG_SH3_3	408	414	PF00018	0.529
LIG_SH3_3	570	576	PF00018	0.395
LIG_SH3_3	618	624	PF00018	0.570
LIG_SH3_3	708	714	PF00018	0.467
LIG_SH3_3	755	761	PF00018	0.510
LIG_Sin3_3	1019	1026	PF02671	0.570
LIG_SUMO_SIM_anti_2	160	168	PF11976	0.447
LIG_SUMO_SIM_anti_2	29	36	PF11976	0.318
LIG_SUMO_SIM_par_1	181	191	PF11976	0.322
LIG_SUMO_SIM_par_1	60	68	PF11976	0.445
LIG_TRAF2_1	13	16	PF00917	0.377
LIG_TRAF2_1	3	6	PF00917	0.523
LIG_TRAF2_1	361	364	PF00917	0.301
LIG_TRAF2_1	421	424	PF00917	0.447
LIG_TRAF2_1	430	433	PF00917	0.447
LIG_TRAF2_1	713	716	PF00917	0.492
LIG_TRAF2_1	747	750	PF00917	0.534
LIG_TRAF2_1	898	901	PF00917	0.577
LIG_TRFH_1	73	77	PF08558	0.335
LIG_TYR_ITIM	1016	1021	PF00017	0.570
LIG_TYR_ITIM	869	874	PF00017	0.360
LIG_UBA3_1	688	696	PF00899	0.477
LIG_UBA3_1	977	984	PF00899	0.467
LIG_ULM_U2AF65_1	940	945	PF00076	0.461
MOD_CK1_1	102	108	PF00069	0.447
MOD_CK1_1	144	150	PF00069	0.430
MOD_CK1_1	234	240	PF00069	0.505
MOD_CK1_1	248	254	PF00069	0.236
MOD_CK1_1	399	405	PF00069	0.691
MOD_CK1_1	475	481	PF00069	0.301
MOD_CK1_1	581	587	PF00069	0.335
MOD_CK1_1	775	781	PF00069	0.578
MOD_CK1_1	858	864	PF00069	0.360
MOD_CK2_1	10	16	PF00069	0.300
MOD_CK2_1	164	170	PF00069	0.360
MOD_CK2_1	184	190	PF00069	0.180
MOD_CK2_1	271	277	PF00069	0.447
MOD_CK2_1	313	319	PF00069	0.316
MOD_CK2_1	507	513	PF00069	0.376
MOD_CK2_1	710	716	PF00069	0.492
MOD_CK2_1	744	750	PF00069	0.494
MOD_CMANNOS	944	947	PF00535	0.363
MOD_Cter_Amidation	266	269	PF01082	0.366
MOD_Cter_Amidation	938	941	PF01082	0.496
MOD_GlcNHglycan	104	107	PF01048	0.366
MOD_GlcNHglycan	221	224	PF01048	0.447
MOD_GlcNHglycan	247	250	PF01048	0.432
MOD_GlcNHglycan	257	260	PF01048	0.227
MOD_GlcNHglycan	369	372	PF01048	0.301
MOD_GlcNHglycan	398	401	PF01048	0.698
MOD_GlcNHglycan	40	43	PF01048	0.300
MOD_GlcNHglycan	405	408	PF01048	0.602
MOD_GlcNHglycan	561	564	PF01048	0.301
MOD_GlcNHglycan	910	913	PF01048	0.474
MOD_GlcNHglycan	937	940	PF01048	0.599
MOD_GSK3_1	118	125	PF00069	0.496
MOD_GSK3_1	171	178	PF00069	0.322
MOD_GSK3_1	213	220	PF00069	0.400
MOD_GSK3_1	241	248	PF00069	0.492
MOD_GSK3_1	292	299	PF00069	0.367
MOD_GSK3_1	334	341	PF00069	0.486
MOD_GSK3_1	367	374	PF00069	0.301
MOD_GSK3_1	394	401	PF00069	0.620
MOD_GSK3_1	464	471	PF00069	0.316
MOD_GSK3_1	48	55	PF00069	0.335
MOD_GSK3_1	576	583	PF00069	0.301
MOD_GSK3_1	718	725	PF00069	0.581
MOD_GSK3_1	744	751	PF00069	0.562
MOD_GSK3_1	770	777	PF00069	0.541
MOD_GSK3_1	781	788	PF00069	0.440
MOD_GSK3_1	854	861	PF00069	0.315
MOD_GSK3_1	904	911	PF00069	0.414
MOD_N-GLC_1	213	218	PF02516	0.447
MOD_N-GLC_1	475	480	PF02516	0.301
MOD_N-GLC_1	839	844	PF02516	0.370
MOD_N-GLC_1	884	889	PF02516	0.540
MOD_NEK2_1	1021	1026	PF00069	0.477
MOD_NEK2_1	261	266	PF00069	0.301
MOD_NEK2_1	403	408	PF00069	0.672
MOD_NEK2_1	559	564	PF00069	0.301
MOD_NEK2_1	619	624	PF00069	0.491
MOD_NEK2_1	637	642	PF00069	0.491
MOD_NEK2_1	688	693	PF00069	0.477
MOD_NEK2_1	839	844	PF00069	0.524
MOD_NEK2_1	853	858	PF00069	0.233
MOD_NEK2_1	908	913	PF00069	0.477
MOD_NEK2_2	184	189	PF00069	0.316
MOD_NEK2_2	296	301	PF00069	0.447
MOD_NEK2_2	52	57	PF00069	0.360
MOD_NEK2_2	594	599	PF00069	0.301
MOD_PIKK_1	20	26	PF00454	0.335
MOD_PIKK_1	772	778	PF00454	0.543
MOD_PK_1	490	496	PF00069	0.447
MOD_PK_1	830	836	PF00069	0.482
MOD_PKA_1	999	1005	PF00069	0.513
MOD_PKA_2	999	1005	PF00069	0.513
MOD_PKB_1	828	836	PF00069	0.482
MOD_Plk_1	169	175	PF00069	0.301
MOD_Plk_1	334	340	PF00069	0.322
MOD_Plk_1	462	468	PF00069	0.366
MOD_Plk_1	605	611	PF00069	0.497
MOD_Plk_1	99	105	PF00069	0.438
MOD_Plk_2-3	468	474	PF00069	0.316
MOD_Plk_2-3	718	724	PF00069	0.482
MOD_Plk_4	248	254	PF00069	0.322
MOD_Plk_4	334	340	PF00069	0.340
MOD_Plk_4	490	496	PF00069	0.434
MOD_Plk_4	855	861	PF00069	0.360
MOD_Plk_4	904	910	PF00069	0.372
MOD_ProDKin_1	217	223	PF00069	0.380
MOD_ProDKin_1	231	237	PF00069	0.273
MOD_ProDKin_1	313	319	PF00069	0.360
MOD_ProDKin_1	371	377	PF00069	0.301
MOD_ProDKin_1	710	716	PF00069	0.462
MOD_SUMO_rev_2	289	295	PF00179	0.306
TRG_DiLeu_BaEn_1	901	906	PF01217	0.450
TRG_DiLeu_BaEn_1	962	967	PF01217	0.513
TRG_DiLeu_BaEn_2	93	99	PF01217	0.316
TRG_DiLeu_BaEn_2	971	977	PF01217	0.570
TRG_DiLeu_BaEn_4	749	755	PF01217	0.557
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.344
TRG_DiLeu_BaLyEn_6	555	560	PF01217	0.366
TRG_DiLeu_BaLyEn_6	671	676	PF01217	0.564
TRG_ENDOCYTIC_2	1018	1021	PF00928	0.570
TRG_ENDOCYTIC_2	272	275	PF00928	0.447
TRG_ENDOCYTIC_2	871	874	PF00928	0.360
TRG_ENDOCYTIC_2	987	990	PF00928	0.467
TRG_ER_diArg_1	417	420	PF00400	0.387
TRG_ER_diArg_1	801	804	PF00400	0.491
TRG_ER_diArg_1	827	830	PF00400	0.562
TRG_NES_CRM1_1	614	626	PF08389	0.513
TRG_NLS_MonoExtC_3	264	269	PF00514	0.366
TRG_NLS_MonoExtN_4	937	944	PF00514	0.474
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.366
TRG_Pf-PMV_PEXEL_1	551	556	PF00026	0.340
TRG_Pf-PMV_PEXEL_1	557	561	PF00026	0.293
TRG_Pf-PMV_PEXEL_1	674	678	PF00026	0.277
TRG_Pf-PMV_PEXEL_1	785	790	PF00026	0.219

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0Q7	Leptomonas seymouri	78%	100%
A0A0N1IJ85	Leptomonas seymouri	29%	90%
A0A0S4IRG8	Bodo saltans	45%	100%
A0A0S4JDE8	Bodo saltans	30%	85%
A0A1X0NX04	Trypanosomatidae	55%	97%
A0A1X0P5N5	Trypanosomatidae	30%	86%
A0A3Q8IIG4	Leishmania donovani	28%	90%
A0A3R7MAM2	Trypanosoma rangeli	31%	86%
A0A3R7MK28	Trypanosoma rangeli	56%	100%
A0A3S7WXL3	Leishmania donovani	97%	100%
A0AVT1	Homo sapiens	34%	99%
A3KMV5	Bos taurus	36%	99%
A4HCT1	Leishmania braziliensis	89%	100%
A4HMX3	Leishmania braziliensis	28%	90%
A4I0A5	Leishmania infantum	97%	100%
A4IBJ4	Leishmania infantum	28%	90%
C9ZV28	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	99%
C9ZZ47	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	86%
E9AFD0	Leishmania major	28%	100%
E9AW70	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9B6I5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	90%
O94609	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
P20973	Triticum aestivum	33%	99%
P22314	Homo sapiens	36%	99%
P22515	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
P31251	Triticum aestivum	33%	99%
P31252	Triticum aestivum	32%	99%
P31254	Mus musculus	35%	99%
P41226	Homo sapiens	31%	100%
P52495	Candida albicans (strain WO-1)	36%	100%
P92974	Arabidopsis thaliana	34%	97%
P93028	Arabidopsis thaliana	34%	97%
Q02053	Mus musculus	36%	99%
Q29504	Oryctolagus cuniculus	36%	99%
Q55C16	Dictyostelium discoideum	36%	100%
Q5U300	Rattus norvegicus	37%	99%
Q8C7R4	Mus musculus	34%	99%
V5BB41	Trypanosoma cruzi	56%	100%