Putative ubiquitin-conjugating enzyme e2

Quick info Annotations Localization Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin-conjugating enzyme E2, putative

Species:

Leishmania major

UniProt:

Q9GNC1_LEIMA

TriTrypDb:

LmjF.35.1300 , LMJLV39_350019400 , LMJSD75_350018600

Length:

148

Annotations

Annotations by Jardim et al.

Protein modification, ubiquitin-conjugating enzyme e2

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 6
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

Q9GNC1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9GNC1

Function

Biological processes
Term	Name	Level	Count
GO:0000209	protein polyubiquitination	8	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0016567	protein ubiquitination	7	2
GO:0019538	protein metabolic process	3	2
GO:0032446	protein modification by small protein conjugation	6	2
GO:0036211	protein modification process	4	2
GO:0043170	macromolecule metabolic process	3	2
GO:0043412	macromolecule modification	4	2
GO:0044238	primary metabolic process	2	2
GO:0070647	protein modification by small protein conjugation or removal	5	2
GO:0071704	organic substance metabolic process	2	2
GO:1901564	organonitrogen compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	13
GO:0003824	catalytic activity	1	13
GO:0004842	ubiquitin-protein transferase activity	4	3
GO:0005488	binding	1	13
GO:0005524	ATP binding	5	13
GO:0016740	transferase activity	2	12
GO:0016874	ligase activity	2	8
GO:0017076	purine nucleotide binding	4	13
GO:0019787	ubiquitin-like protein transferase activity	3	3
GO:0030554	adenyl nucleotide binding	5	13
GO:0032553	ribonucleotide binding	3	13
GO:0032555	purine ribonucleotide binding	4	13
GO:0032559	adenyl ribonucleotide binding	5	13
GO:0035639	purine ribonucleoside triphosphate binding	4	13
GO:0036094	small molecule binding	2	13
GO:0043167	ion binding	2	13
GO:0043168	anion binding	3	13
GO:0061631	ubiquitin conjugating enzyme activity	5	3
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4	3
GO:0097159	organic cyclic compound binding	2	13
GO:0097367	carbohydrate derivative binding	2	13
GO:0140096	catalytic activity, acting on a protein	2	3
GO:1901265	nucleoside phosphate binding	3	13
GO:1901363	heterocyclic compound binding	2	13
GO:0016746	acyltransferase activity	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	4	6	PF00675	0.312
CLV_PCSK_KEX2_1	4	6	PF00082	0.317
CLV_PCSK_SKI1_1	102	106	PF00082	0.337
CLV_PCSK_SKI1_1	132	136	PF00082	0.370
CLV_PCSK_SKI1_1	8	12	PF00082	0.326
DEG_COP1_1	117	124	PF00400	0.337
DOC_CYCLIN_RxL_1	99	109	PF00134	0.337
DOC_CYCLIN_yClb1_LxF_4	65	70	PF00134	0.312
DOC_MAPK_MEF2A_6	91	100	PF00069	0.337
DOC_PP1_RVXF_1	65	71	PF00149	0.312
DOC_PP4_FxxP_1	63	66	PF00568	0.312
DOC_USP7_MATH_1	19	23	PF00917	0.352
DOC_USP7_UBL2_3	11	15	PF12436	0.381
DOC_WW_Pin1_4	41	46	PF00397	0.312
DOC_WW_Pin1_4	92	97	PF00397	0.323
LIG_14-3-3_CanoR_1	126	135	PF00244	0.357
LIG_BIR_II_1	1	5	PF00653	0.416
LIG_BRCT_BRCA1_1	28	32	PF00533	0.435
LIG_FHA_1	69	75	PF00498	0.314
LIG_FHA_2	136	142	PF00498	0.337
LIG_IRF3_LxIS_1	96	101	PF10401	0.323
LIG_LIR_Apic_2	60	66	PF02991	0.323
LIG_Pex14_1	142	146	PF04695	0.391
LIG_PTB_Apo_2	51	58	PF02174	0.312
LIG_SH3_2	62	67	PF14604	0.312
LIG_SH3_3	113	119	PF00018	0.352
LIG_SH3_3	59	65	PF00018	0.323
LIG_SUMO_SIM_par_1	103	109	PF11976	0.352
MOD_CK1_1	106	112	PF00069	0.327
MOD_CK2_1	135	141	PF00069	0.349
MOD_GlcNHglycan	21	24	PF01048	0.352
MOD_GSK3_1	92	99	PF00069	0.337
MOD_N-GLC_1	135	140	PF02516	0.337
MOD_N-GLC_1	19	24	PF02516	0.323
MOD_NEK2_1	135	140	PF00069	0.323
MOD_NEK2_1	68	73	PF00069	0.312
MOD_NEK2_1	98	103	PF00069	0.323
MOD_Plk_4	106	112	PF00069	0.323
MOD_Plk_4	34	40	PF00069	0.312
MOD_ProDKin_1	41	47	PF00069	0.312
MOD_ProDKin_1	92	98	PF00069	0.323
TRG_ER_diArg_1	3	5	PF00400	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6R4	Leptomonas seymouri	38%	81%
A0A0N1I1Z1	Leptomonas seymouri	38%	95%
A0A0N1I707	Leptomonas seymouri	98%	100%
A0A0N1IA93	Leptomonas seymouri	32%	77%
A0A0N1PAW7	Leptomonas seymouri	37%	70%
A0A0N1PB60	Leptomonas seymouri	50%	99%
A0A0S4IJE0	Bodo saltans	43%	67%
A0A0S4INP2	Bodo saltans	28%	77%
A0A0S4IWQ9	Bodo saltans	31%	77%
A0A0S4J8W6	Bodo saltans	50%	99%
A0A0S4JGV6	Bodo saltans	76%	100%
A0A0S4JJB5	Bodo saltans	38%	84%
A0A0S4JK56	Bodo saltans	75%	99%
A0A0S4JQY0	Bodo saltans	35%	70%
A0A0S4JRZ8	Bodo saltans	42%	92%
A0A0S4JS17	Bodo saltans	84%	100%
A0A0S4KHH6	Bodo saltans	30%	67%
A0A0S4KHR4	Bodo saltans	29%	85%
A0A0S4KIJ1	Bodo saltans	43%	82%
A0A0S4KJ33	Bodo saltans	91%	100%
A0A1B0GUS4	Homo sapiens	41%	96%
A0A1X0NH68	Trypanosomatidae	96%	100%
A0A1X0NLS0	Trypanosomatidae	48%	99%
A0A1X0NPI5	Trypanosomatidae	43%	92%
A0A1X0NT81	Trypanosomatidae	39%	71%
A0A1X0NVW4	Trypanosomatidae	28%	69%
A0A1X0NW06	Trypanosomatidae	46%	94%
A0A1X0NW44	Trypanosomatidae	35%	70%
A0A3Q8II46	Leishmania donovani	100%	100%
A0A3R7K708	Trypanosoma rangeli	47%	98%
A0A3R7M279	Trypanosoma rangeli	26%	74%
A0A3S5H5C0	Leishmania donovani	50%	100%
A0A3S5H604	Leishmania donovani	34%	81%
A0A3S7WYH9	Leishmania donovani	29%	77%
A0A3S7WYK3	Leishmania donovani	37%	95%
A0A422MVJ2	Trypanosoma rangeli	96%	100%
A0A422MW82	Trypanosoma rangeli	31%	91%
A0A422MY24	Trypanosoma rangeli	40%	92%
A0A422NDI3	Trypanosoma rangeli	39%	70%
A0A422NJI9	Trypanosoma rangeli	36%	70%
A0A422NWQ7	Trypanosoma rangeli	43%	96%
A0A451EJH5	Leishmania donovani	37%	97%
A1L3K1	Xenopus laevis	44%	66%
A3KN22	Bos taurus	34%	81%
A4H3D5	Leishmania braziliensis	39%	66%
A4H402	Leishmania braziliensis	50%	100%
A4H533	Leishmania braziliensis	37%	82%
A4HDN1	Leishmania braziliensis	29%	77%
A4HDS4	Leishmania braziliensis	37%	95%
A4HLY8	Leishmania braziliensis	34%	100%
A4HMF2	Leishmania braziliensis	97%	100%
A4HRN6	Leishmania infantum	37%	97%
A4HS64	Leishmania infantum	50%	100%
A4HTB1	Leishmania infantum	34%	81%
A4I122	Leishmania infantum	37%	95%
A4IB24	Leishmania infantum	100%	100%
A5PJC4	Bos taurus	36%	97%
A5PKP9	Xenopus laevis	74%	100%
A6H795	Bos taurus	38%	98%
A7SE05	Nematostella vectensis	36%	73%
B3MQV3	Drosophila ananassae	35%	71%
B3NWW9	Drosophila erecta	35%	71%
B4H9W2	Drosophila persimilis	35%	71%
B4IF39	Drosophila sechellia	35%	71%
B4JKB7	Drosophila grimshawi	37%	71%
B4L7V4	Drosophila mojavensis	37%	72%
B4MA02	Drosophila virilis	37%	71%
B4N208	Drosophila willistoni	35%	71%
B4Q2J2	Drosophila yakuba	35%	71%
B4R6G1	Drosophila simulans	35%	71%
B5DEI4	Rattus norvegicus	38%	98%
B5DFI8	Rattus norvegicus	44%	66%
B5DKM4	Drosophila pseudoobscura pseudoobscura	35%	71%
C1C3R6	Lithobates catesbeianus	37%	70%
C3Z724	Branchiostoma floridae	35%	69%
C9ZJ18	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	75%
C9ZMR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	91%
C9ZMW8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	67%
C9ZMZ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	89%
C9ZNM0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	98%	100%
C9ZRM5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	67%
C9ZUL2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	86%
C9ZW85	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	95%
C9ZWD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	75%
C9ZY61	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	99%
D0A9T7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	69%
D3ZDK2	Rattus norvegicus	72%	100%
E9ACB4	Leishmania major	37%	97%
E9AH78	Leishmania infantum	29%	77%
E9AJK2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	97%
E9AK51	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9ALA2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	81%
E9AX16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	77%
E9AX59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	95%
E9B4Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	89%
E9B609	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
I1RRW0	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	43%	86%
O00102	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	89%
O00103	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	84%
O00762	Homo sapiens	40%	83%
O09181	Mesocricetus auratus	35%	94%
O13685	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	100%
O14933	Homo sapiens	39%	97%
O23239	Arabidopsis thaliana	37%	92%
O45495	Caenorhabditis elegans	35%	100%
O60015	Pichia angusta	37%	79%
O74196	Colletotrichum gloeosporioides	73%	100%
O74201	Candida albicans (strain SC5314 / ATCC MYA-2876)	40%	83%
O74549	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	84%
O74810	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	47%	68%
P06104	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	86%
P0C8G3	African swine fever virus (isolate Pig/Kenya/KEN-50/1950)	40%	68%
P0C8G4	African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)	39%	68%
P0C8G5	African swine fever virus (isolate Warthog/Namibia/Wart80/1980)	40%	67%
P0CS16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	40%	88%
P0CS17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	40%	88%
P15731	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	73%	100%
P15732	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	72%	100%
P16577	Triticum aestivum	37%	80%
P21734	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	69%
P23566	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	98%
P25153	Drosophila melanogaster	42%	98%
P25865	Arabidopsis thaliana	42%	97%
P25866	Triticum aestivum	42%	97%
P25867	Drosophila melanogaster	75%	100%
P25868	Triticum aestivum	31%	88%
P25869	African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)	46%	69%
P27949	African swine fever virus (strain Badajoz 1971 Vero-adapted)	40%	69%
P28263	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	68%
P29340	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	81%
P34477	Caenorhabditis elegans	37%	90%
P35128	Drosophila melanogaster	47%	98%
P35129	Caenorhabditis elegans	74%	100%
P35130	Medicago sativa	42%	97%
P35131	Arabidopsis thaliana	71%	100%
P35132	Arabidopsis thaliana	72%	100%
P35133	Arabidopsis thaliana	72%	100%
P35134	Arabidopsis thaliana	73%	100%
P35135	Solanum lycopersicum	72%	100%
P40984	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	94%
P42743	Arabidopsis thaliana	37%	92%
P42745	Arabidopsis thaliana	42%	97%
P42746	Arabidopsis thaliana	44%	99%
P42747	Arabidopsis thaliana	32%	89%
P42748	Arabidopsis thaliana	39%	79%
P42749	Arabidopsis thaliana	38%	80%
P42750	Arabidopsis thaliana	38%	81%
P43102	Candida albicans	71%	100%
P46595	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	74%	100%
P49428	Komagataella pastoris	32%	73%
P49459	Homo sapiens	42%	97%
P50623	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	94%
P51668	Homo sapiens	72%	100%
P51965	Homo sapiens	60%	77%
P52478	Caenorhabditis elegans	39%	77%
P52482	Mus musculus	60%	77%
P52483	Mus musculus	61%	71%
P52484	Caenorhabditis elegans	41%	69%
P52486	Drosophila melanogaster	43%	74%
P52487	Drosophila melanogaster	37%	97%
P52490	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	97%
P52492	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	95%
P52493	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	98%
P53152	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P56616	Xenopus laevis	38%	83%
P60604	Homo sapiens	36%	90%
P60605	Mus musculus	36%	90%
P61077	Homo sapiens	73%	100%
P61078	Rattus norvegicus	73%	100%
P61079	Mus musculus	73%	100%
P61080	Mus musculus	72%	100%
P61081	Homo sapiens	34%	81%
P61082	Mus musculus	34%	81%
P61085	Bos taurus	43%	74%
P61086	Homo sapiens	43%	74%
P61087	Mus musculus	43%	74%
P61088	Homo sapiens	51%	97%
P61089	Mus musculus	51%	97%
P62253	Homo sapiens	37%	87%
P62254	Mus musculus	37%	87%
P62255	Rattus norvegicus	37%	87%
P62256	Homo sapiens	35%	81%
P62257	Mus musculus	35%	81%
P62837	Homo sapiens	74%	100%
P62838	Mus musculus	74%	100%
P62839	Rattus norvegicus	74%	100%
P62840	Xenopus laevis	74%	100%
P63146	Homo sapiens	41%	97%
P63147	Mus musculus	41%	97%
P63148	Oryctolagus cuniculus	41%	97%
P63149	Rattus norvegicus	41%	97%
P63279	Homo sapiens	35%	94%
P63280	Mus musculus	35%	94%
P63281	Rattus norvegicus	35%	94%
P63282	Xenopus laevis	35%	94%
P63283	Gallus gallus	35%	94%
P68036	Homo sapiens	42%	96%
P68037	Mus musculus	42%	96%
P70711	Rattus norvegicus	72%	100%
P78717	Fusarium solani	40%	98%
Q02159	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	90%
Q06AA9	Sus scrofa	73%	100%
Q08BH7	Danio rerio	43%	76%
Q0P5K3	Bos taurus	51%	97%
Q16763	Homo sapiens	44%	67%
Q17QG5	Bos taurus	36%	90%
Q1JPX4	Danio rerio	38%	98%
Q1RML1	Bos taurus	44%	66%
Q1RMW1	Bos taurus	31%	80%
Q1RMX2	Bos taurus	74%	100%
Q21633	Caenorhabditis elegans	41%	97%
Q28CQ4	Xenopus tropicalis	35%	94%
Q28F89	Xenopus tropicalis	37%	70%
Q28FC1	Xenopus tropicalis	38%	98%
Q2EF73	Ictidomys tridecemlineatus	35%	94%
Q2T9X7	Bos taurus	61%	71%
Q2TA10	Bos taurus	72%	100%
Q32LD2	Bos taurus	40%	76%
Q32LN1	Bos taurus	35%	81%
Q32P99	Bos taurus	41%	97%
Q32PA5	Bos taurus	41%	83%
Q3MHP1	Bos taurus	42%	96%
Q3UWQ3	Mus musculus	36%	80%
Q3ZCF7	Bos taurus	72%	100%
Q42540	Arabidopsis thaliana	33%	89%
Q42541	Arabidopsis thaliana	34%	89%
Q42551	Arabidopsis thaliana	34%	92%
Q4PFA5	Ustilago maydis (strain 521 / FGSC 9021)	40%	80%
Q4QAB7	Leishmania major	37%	95%
Q4QAG0	Leishmania major	28%	77%
Q4QIK2	Leishmania major	35%	100%
Q4R4I1	Macaca fascicularis	51%	97%
Q4R5N4	Macaca fascicularis	73%	100%
Q4R5Y8	Macaca fascicularis	37%	87%
Q4R9D1	Macaca fascicularis	41%	83%
Q4V8J2	Rattus norvegicus	36%	97%
Q4V908	Danio rerio	37%	67%
Q4VBH4	Danio rerio	39%	98%
Q4WLA7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	98%
Q54I43	Dictyostelium discoideum	35%	69%
Q54XS6	Dictyostelium discoideum	45%	97%
Q553F3	Dictyostelium discoideum	41%	98%
Q55EY8	Dictyostelium discoideum	46%	99%
Q58FS2	Trichoderma harzianum	40%	98%
Q5JXB2	Homo sapiens	46%	97%
Q5M8Y2	Xenopus tropicalis	32%	80%
Q5R4V7	Pongo abelii	73%	100%
Q5R5I4	Pongo abelii	42%	96%
Q5R7J6	Pongo abelii	51%	97%
Q5RF84	Pongo abelii	36%	90%
Q5U203	Rattus norvegicus	32%	80%
Q5UQC9	Acanthamoeba polyphaga mimivirus	36%	94%
Q5ZKX6	Gallus gallus	32%	80%
Q6BU36	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	39%	88%
Q6C093	Yarrowia lipolytica (strain CLIB 122 / E 150)	37%	98%
Q6C9W0	Yarrowia lipolytica (strain CLIB 122 / E 150)	33%	83%
Q6CSW8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	35%	80%
Q6CUD9	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	37%	90%
Q6DCZ9	Xenopus laevis	34%	81%
Q6FR76	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	39%	89%
Q6FVQ8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	79%
Q6IRC7	Xenopus laevis	32%	80%
Q6NY82	Danio rerio	33%	80%
Q6P8D9	Xenopus tropicalis	34%	81%
Q6Y1Z4	Pagrus major	34%	94%
Q6ZWY6	Mus musculus	72%	100%
Q75EB8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	38%	87%
Q76EZ2	Xenopus laevis	38%	70%
Q7K738	Drosophila melanogaster	37%	96%
Q7ZY08	Xenopus laevis	47%	77%
Q86IZ3	Dictyostelium discoideum	41%	99%
Q86K32	Dictyostelium discoideum	50%	96%
Q8AVU2	Xenopus laevis	43%	70%
Q8L7T3	Arabidopsis thaliana	43%	82%
Q8LGF7	Arabidopsis thaliana	39%	94%
Q8S919	Oryza sativa subsp. japonica	71%	100%
Q8S920	Oryza sativa subsp. japonica	74%	100%
Q8SSK3	Encephalitozoon cuniculi (strain GB-M1)	29%	69%
Q8VDW4	Mus musculus	38%	98%
Q91W82	Mus musculus	60%	74%
Q921J4	Mus musculus	44%	66%
Q94490	Dictyostelium discoideum	56%	100%
Q94A97	Arabidopsis thaliana	51%	97%
Q94F47	Arabidopsis thaliana	71%	100%
Q95017	Caenorhabditis elegans	32%	89%
Q95044	Spisula solidissima	43%	84%
Q95XX0	Caenorhabditis elegans	53%	98%
Q969M7	Homo sapiens	32%	80%
Q969T4	Homo sapiens	61%	71%
Q96B02	Homo sapiens	38%	98%
Q96LR5	Homo sapiens	60%	74%
Q96UP5	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	98%
Q9C8X7	Arabidopsis thaliana	55%	96%
Q9C9Y7	Arabidopsis thaliana	65%	99%
Q9CQ37	Mus musculus	42%	73%
Q9CY34	Mus musculus	32%	80%
Q9D1C1	Mus musculus	41%	83%
Q9DDJ0	Danio rerio	35%	94%
Q9EQX9	Rattus norvegicus	50%	97%
Q9FI61	Arabidopsis thaliana	48%	77%
Q9FKT3	Arabidopsis thaliana	69%	100%
Q9FMM0	Arabidopsis thaliana	38%	92%
Q9FWT2	Arabidopsis thaliana	38%	92%
Q9FZ48	Arabidopsis thaliana	51%	97%
Q9LJD7	Arabidopsis thaliana	53%	81%
Q9LJZ5	Arabidopsis thaliana	44%	82%
Q9NED4	Leishmania major	50%	100%
Q9NGP4	Dictyostelium discoideum	32%	93%
Q9NPD8	Homo sapiens	41%	75%
Q9P6I1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	92%
Q9P7R4	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	80%
Q9QZU9	Mus musculus	34%	97%
Q9SDY5	Arabidopsis thaliana	36%	80%
Q9SLE4	Arabidopsis thaliana	69%	100%
Q9UTN8	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	46%	95%
Q9UVR2	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	74%	100%
Q9VSF3	Drosophila melanogaster	36%	82%
Q9VTY6	Drosophila melanogaster	38%	83%
Q9VX25	Drosophila melanogaster	35%	71%
Q9W6H5	Danio rerio	35%	94%
Q9XVK5	Caenorhabditis elegans	30%	82%
Q9XWF6	Caenorhabditis elegans	41%	97%
Q9Y2X8	Homo sapiens	74%	100%
Q9Y818	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	89%
Q9Z255	Mus musculus	42%	97%
Q9ZU75	Arabidopsis thaliana	36%	80%
V5BDP3	Trypanosoma cruzi	48%	98%
V5BVS1	Trypanosoma cruzi	36%	66%
V5BYE2	Trypanosoma cruzi	38%	92%