Uncharacterized protein L3377.3

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9GN98_LEIMA

TriTrypDb:

LmjF.35.1290 , LMJLV39_350019300 , LMJSD75_350018500

Length:

249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9GN98

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9GN98

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	167	171	PF00656	0.478
CLV_C14_Caspase3-7	199	203	PF00656	0.428
CLV_NRD_NRD_1	118	120	PF00675	0.626
CLV_NRD_NRD_1	195	197	PF00675	0.486
CLV_NRD_NRD_1	247	249	PF00675	0.590
CLV_NRD_NRD_1	99	101	PF00675	0.439
CLV_PCSK_KEX2_1	118	120	PF00082	0.672
CLV_PCSK_KEX2_1	195	197	PF00082	0.490
CLV_PCSK_KEX2_1	213	215	PF00082	0.377
CLV_PCSK_KEX2_1	246	248	PF00082	0.637
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.650
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.520
CLV_PCSK_PC7_1	209	215	PF00082	0.497
CLV_PCSK_PC7_1	243	249	PF00082	0.634
CLV_PCSK_SKI1_1	18	22	PF00082	0.533
DEG_SCF_TRCP1_1	232	238	PF00400	0.584
DOC_CYCLIN_RxL_1	156	167	PF00134	0.543
DOC_PP2B_PxIxI_1	12	18	PF00149	0.430
DOC_USP7_MATH_1	141	145	PF00917	0.694
DOC_USP7_MATH_1	67	71	PF00917	0.751
DOC_WW_Pin1_4	1	6	PF00397	0.693
DOC_WW_Pin1_4	48	53	PF00397	0.564
DOC_WW_Pin1_4	73	78	PF00397	0.716
DOC_WW_Pin1_4	79	84	PF00397	0.608
LIG_14-3-3_CanoR_1	140	148	PF00244	0.742
LIG_14-3-3_CanoR_1	18	23	PF00244	0.487
LIG_14-3-3_CanoR_1	37	41	PF00244	0.452
LIG_14-3-3_CterR_2	246	249	PF00244	0.604
LIG_Actin_WH2_2	185	203	PF00022	0.538
LIG_FHA_1	12	18	PF00498	0.383
LIG_FHA_1	158	164	PF00498	0.528
LIG_FHA_1	37	43	PF00498	0.431
LIG_FHA_2	110	116	PF00498	0.575
LIG_LIR_Apic_2	107	111	PF02991	0.510
LIG_MYND_1	83	87	PF01753	0.553
LIG_Pex14_2	104	108	PF04695	0.417
LIG_PTB_Apo_2	27	34	PF02174	0.468
LIG_REV1ctd_RIR_1	31	41	PF16727	0.484
LIG_SH2_STAT5	103	106	PF00017	0.335
LIG_SH3_1	84	90	PF00018	0.541
LIG_SH3_3	80	86	PF00018	0.524
LIG_SxIP_EBH_1	234	248	PF03271	0.447
LIG_TRAF2_1	112	115	PF00917	0.587
MOD_CDK_SPK_2	79	84	PF00069	0.627
MOD_CK1_1	123	129	PF00069	0.617
MOD_CK1_1	54	60	PF00069	0.704
MOD_CK1_1	6	12	PF00069	0.420
MOD_CK1_1	79	85	PF00069	0.426
MOD_CK2_1	109	115	PF00069	0.520
MOD_CK2_1	21	27	PF00069	0.406
MOD_CK2_1	62	68	PF00069	0.694
MOD_GlcNHglycan	126	129	PF01048	0.720
MOD_GlcNHglycan	182	185	PF01048	0.513
MOD_GlcNHglycan	209	212	PF01048	0.518
MOD_GlcNHglycan	218	223	PF01048	0.541
MOD_GlcNHglycan	232	235	PF01048	0.722
MOD_GlcNHglycan	5	8	PF01048	0.599
MOD_GlcNHglycan	53	56	PF01048	0.667
MOD_GlcNHglycan	65	68	PF01048	0.693
MOD_GlcNHglycan	69	72	PF01048	0.747
MOD_GlcNHglycan	78	81	PF01048	0.635
MOD_GSK3_1	120	127	PF00069	0.636
MOD_GSK3_1	218	225	PF00069	0.598
MOD_GSK3_1	3	10	PF00069	0.636
MOD_GSK3_1	63	70	PF00069	0.744
MOD_NEK2_1	96	101	PF00069	0.377
MOD_PIKK_1	141	147	PF00454	0.736
MOD_PKA_2	146	152	PF00069	0.481
MOD_PKA_2	230	236	PF00069	0.595
MOD_PKA_2	36	42	PF00069	0.429
MOD_PKA_2	96	102	PF00069	0.534
MOD_Plk_1	157	163	PF00069	0.499
MOD_Plk_4	11	17	PF00069	0.390
MOD_Plk_4	187	193	PF00069	0.608
MOD_Plk_4	236	242	PF00069	0.476
MOD_ProDKin_1	1	7	PF00069	0.690
MOD_ProDKin_1	48	54	PF00069	0.569
MOD_ProDKin_1	73	79	PF00069	0.717
TRG_ENDOCYTIC_2	103	106	PF00928	0.344
TRG_ER_diArg_1	245	248	PF00400	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5V4	Leptomonas seymouri	51%	100%
A0A1X0NIU6	Trypanosomatidae	32%	100%
A0A3R7JUY0	Trypanosoma rangeli	30%	100%
A0A3S7X907	Leishmania donovani	93%	100%
A4HMF1	Leishmania braziliensis	72%	100%
A4IB23	Leishmania infantum	92%	100%
C9ZNL9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9B608	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%