Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9BLQ5_LEIMA

TriTrypDb:

LmjF.04.0300 , LMJLV39_040007800 , LMJSD75_040007900

Length:

252

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

Q9BLQ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9BLQ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	24	28	PF00656	0.598
CLV_NRD_NRD_1	109	111	PF00675	0.519
CLV_NRD_NRD_1	146	148	PF00675	0.425
CLV_NRD_NRD_1	159	161	PF00675	0.279
CLV_NRD_NRD_1	238	240	PF00675	0.567
CLV_PCSK_FUR_1	113	117	PF00082	0.504
CLV_PCSK_KEX2_1	109	111	PF00082	0.519
CLV_PCSK_KEX2_1	115	117	PF00082	0.536
CLV_PCSK_KEX2_1	127	129	PF00082	0.295
CLV_PCSK_KEX2_1	146	148	PF00082	0.425
CLV_PCSK_KEX2_1	161	163	PF00082	0.405
CLV_PCSK_KEX2_1	238	240	PF00082	0.527
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.523
CLV_PCSK_PC1ET2_1	127	129	PF00082	0.578
CLV_PCSK_PC1ET2_1	161	163	PF00082	0.405
CLV_PCSK_SKI1_1	120	124	PF00082	0.537
CLV_PCSK_SKI1_1	128	132	PF00082	0.431
DOC_CKS1_1	218	223	PF01111	0.531
DOC_CYCLIN_yClb3_PxF_3	102	110	PF00134	0.424
DOC_USP7_UBL2_3	127	131	PF12436	0.549
DOC_WW_Pin1_4	167	172	PF00397	0.463
DOC_WW_Pin1_4	217	222	PF00397	0.540
LIG_14-3-3_CanoR_1	120	129	PF00244	0.401
LIG_14-3-3_CanoR_1	4	14	PF00244	0.531
LIG_BIR_II_1	1	5	PF00653	0.490
LIG_eIF4E_1	78	84	PF01652	0.521
LIG_FHA_1	211	217	PF00498	0.611
LIG_FHA_1	60	66	PF00498	0.673
LIG_FHA_2	121	127	PF00498	0.337
LIG_FHA_2	136	142	PF00498	0.419
LIG_FHA_2	218	224	PF00498	0.498
LIG_GBD_Chelix_1	83	91	PF00786	0.519
LIG_LIR_Gen_1	126	136	PF02991	0.456
LIG_LIR_Gen_1	138	148	PF02991	0.555
LIG_LIR_Gen_1	75	85	PF02991	0.530
LIG_LIR_Gen_1	8	18	PF02991	0.581
LIG_LIR_Nem_3	126	132	PF02991	0.436
LIG_LIR_Nem_3	138	143	PF02991	0.538
LIG_LIR_Nem_3	42	48	PF02991	0.507
LIG_LIR_Nem_3	75	81	PF02991	0.484
LIG_LIR_Nem_3	8	14	PF02991	0.502
LIG_LIR_Nem_3	86	91	PF02991	0.461
LIG_SH2_CRK	129	133	PF00017	0.440
LIG_SH2_CRK	88	92	PF00017	0.446
LIG_SH2_SRC	199	202	PF00017	0.580
LIG_SH2_STAP1	140	144	PF00017	0.412
LIG_SH2_STAP1	48	52	PF00017	0.503
LIG_SH2_STAT3	3	6	PF00017	0.655
LIG_SH2_STAT5	187	190	PF00017	0.599
LIG_SH2_STAT5	219	222	PF00017	0.496
LIG_SH2_STAT5	233	236	PF00017	0.428
LIG_SH2_STAT5	52	55	PF00017	0.534
LIG_SH3_3	17	23	PF00018	0.663
LIG_SH3_3	99	105	PF00018	0.418
LIG_TYR_ITAM	75	91	PF00017	0.528
LIG_TYR_ITIM	76	81	PF00017	0.440
MOD_CK2_1	217	223	PF00069	0.469
MOD_NEK2_1	174	179	PF00069	0.458
MOD_PKA_2	210	216	PF00069	0.653
MOD_PKB_1	118	126	PF00069	0.335
MOD_Plk_1	174	180	PF00069	0.484
MOD_Plk_4	135	141	PF00069	0.409
MOD_Plk_4	48	54	PF00069	0.516
MOD_ProDKin_1	167	173	PF00069	0.461
MOD_ProDKin_1	217	223	PF00069	0.537
TRG_DiLeu_BaEn_1	79	84	PF01217	0.513
TRG_DiLeu_BaLyEn_6	161	166	PF01217	0.465
TRG_ENDOCYTIC_2	129	132	PF00928	0.441
TRG_ENDOCYTIC_2	140	143	PF00928	0.456
TRG_ENDOCYTIC_2	148	151	PF00928	0.587
TRG_ENDOCYTIC_2	78	81	PF00928	0.443
TRG_ENDOCYTIC_2	88	91	PF00928	0.471
TRG_ER_diArg_1	109	111	PF00400	0.519
TRG_ER_diArg_1	145	147	PF00400	0.436
TRG_ER_diArg_1	178	181	PF00400	0.651
TRG_ER_diArg_1	237	239	PF00400	0.577
TRG_Pf-PMV_PEXEL_1	164	168	PF00026	0.655
TRG_Pf-PMV_PEXEL_1	181	185	PF00026	0.454

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3B4	Leptomonas seymouri	78%	81%
A0A0S4J2A8	Bodo saltans	46%	73%
A0A1X0NL02	Trypanosomatidae	61%	89%
A0A3S5H594	Leishmania donovani	96%	78%
A4H3V0	Leishmania braziliensis	89%	97%
A4HS25	Leishmania infantum	96%	94%
C9ZY18	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	87%
E9AK12	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	97%
V5ATQ3	Trypanosoma cruzi	63%	90%