Uncharacterized protein P883.09

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q9BHG4_LEIMA

TriTrypDb:

LmjF.31.1010 , LMJLV39_310016200 , LMJSD75_310015800

Length:

751

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q9BHG4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q9BHG4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	576	580	PF00656	0.610
CLV_NRD_NRD_1	142	144	PF00675	0.408
CLV_NRD_NRD_1	151	153	PF00675	0.559
CLV_NRD_NRD_1	223	225	PF00675	0.589
CLV_NRD_NRD_1	268	270	PF00675	0.661
CLV_NRD_NRD_1	284	286	PF00675	0.670
CLV_NRD_NRD_1	493	495	PF00675	0.591
CLV_NRD_NRD_1	545	547	PF00675	0.505
CLV_NRD_NRD_1	552	554	PF00675	0.492
CLV_NRD_NRD_1	567	569	PF00675	0.431
CLV_NRD_NRD_1	614	616	PF00675	0.425
CLV_NRD_NRD_1	726	728	PF00675	0.368
CLV_PCSK_FUR_1	22	26	PF00082	0.449
CLV_PCSK_FUR_1	552	556	PF00082	0.428
CLV_PCSK_KEX2_1	142	144	PF00082	0.408
CLV_PCSK_KEX2_1	151	153	PF00082	0.540
CLV_PCSK_KEX2_1	223	225	PF00082	0.620
CLV_PCSK_KEX2_1	24	26	PF00082	0.465
CLV_PCSK_KEX2_1	268	270	PF00082	0.661
CLV_PCSK_KEX2_1	284	286	PF00082	0.670
CLV_PCSK_KEX2_1	493	495	PF00082	0.571
CLV_PCSK_KEX2_1	545	547	PF00082	0.498
CLV_PCSK_KEX2_1	551	553	PF00082	0.492
CLV_PCSK_KEX2_1	554	556	PF00082	0.470
CLV_PCSK_KEX2_1	567	569	PF00082	0.443
CLV_PCSK_KEX2_1	614	616	PF00082	0.444
CLV_PCSK_KEX2_1	726	728	PF00082	0.373
CLV_PCSK_PC1ET2_1	24	26	PF00082	0.395
CLV_PCSK_PC1ET2_1	554	556	PF00082	0.502
CLV_PCSK_PC7_1	548	554	PF00082	0.421
CLV_PCSK_SKI1_1	298	302	PF00082	0.660
CLV_PCSK_SKI1_1	338	342	PF00082	0.667
CLV_PCSK_SKI1_1	635	639	PF00082	0.368
CLV_PCSK_SKI1_1	648	652	PF00082	0.387
CLV_PCSK_SKI1_1	7	11	PF00082	0.374
DEG_APCC_DBOX_1	179	187	PF00400	0.640
DEG_Nend_UBRbox_2	1	3	PF02207	0.695
DEG_SPOP_SBC_1	155	159	PF00917	0.699
DEG_SPOP_SBC_1	164	168	PF00917	0.717
DEG_SPOP_SBC_1	303	307	PF00917	0.469
DOC_ANK_TNKS_1	101	108	PF00023	0.735
DOC_CDC14_PxL_1	501	509	PF14671	0.360
DOC_CDC14_PxL_1	693	701	PF14671	0.585
DOC_CKS1_1	257	262	PF01111	0.329
DOC_CYCLIN_yCln2_LP_2	379	385	PF00134	0.439
DOC_MAPK_gen_1	22	32	PF00069	0.655
DOC_MAPK_gen_1	461	468	PF00069	0.385
DOC_MAPK_gen_1	493	499	PF00069	0.381
DOC_MAPK_gen_1	81	89	PF00069	0.563
DOC_MAPK_MEF2A_6	180	187	PF00069	0.609
DOC_MAPK_MEF2A_6	338	347	PF00069	0.436
DOC_MAPK_MEF2A_6	461	468	PF00069	0.386
DOC_MAPK_RevD_3	127	143	PF00069	0.591
DOC_MAPK_RevD_3	481	494	PF00069	0.379
DOC_PP1_RVXF_1	620	626	PF00149	0.631
DOC_PP2B_LxvP_1	379	382	PF13499	0.387
DOC_PP2B_LxvP_1	93	96	PF13499	0.627
DOC_PP2B_PxIxI_1	327	333	PF00149	0.393
DOC_PP4_FxxP_1	199	202	PF00568	0.688
DOC_USP7_MATH_1	105	109	PF00917	0.736
DOC_USP7_MATH_1	150	154	PF00917	0.675
DOC_USP7_MATH_1	155	159	PF00917	0.700
DOC_USP7_MATH_1	206	210	PF00917	0.745
DOC_USP7_MATH_1	242	246	PF00917	0.661
DOC_USP7_MATH_1	302	306	PF00917	0.560
DOC_USP7_MATH_1	370	374	PF00917	0.548
DOC_USP7_MATH_1	467	471	PF00917	0.341
DOC_USP7_MATH_1	573	577	PF00917	0.681
DOC_USP7_MATH_1	578	582	PF00917	0.645
DOC_USP7_UBL2_3	644	648	PF12436	0.592
DOC_WW_Pin1_4	198	203	PF00397	0.688
DOC_WW_Pin1_4	215	220	PF00397	0.584
DOC_WW_Pin1_4	243	248	PF00397	0.564
DOC_WW_Pin1_4	256	261	PF00397	0.357
DOC_WW_Pin1_4	304	309	PF00397	0.473
DOC_WW_Pin1_4	516	521	PF00397	0.308
DOC_WW_Pin1_4	555	560	PF00397	0.697
DOC_WW_Pin1_4	60	65	PF00397	0.664
DOC_WW_Pin1_4	738	743	PF00397	0.687
LIG_14-3-3_CanoR_1	151	160	PF00244	0.632
LIG_14-3-3_CanoR_1	180	186	PF00244	0.634
LIG_14-3-3_CanoR_1	212	219	PF00244	0.728
LIG_14-3-3_CanoR_1	25	33	PF00244	0.585
LIG_14-3-3_CanoR_1	268	276	PF00244	0.452
LIG_14-3-3_CanoR_1	380	386	PF00244	0.369
LIG_14-3-3_CanoR_1	45	51	PF00244	0.542
LIG_14-3-3_CanoR_1	552	561	PF00244	0.755
LIG_14-3-3_CanoR_1	666	673	PF00244	0.568
LIG_14-3-3_CanoR_1	7	13	PF00244	0.723
LIG_BIR_III_4	530	534	PF00653	0.678
LIG_BRCT_BRCA1_1	157	161	PF00533	0.638
LIG_eIF4E_1	181	187	PF01652	0.611
LIG_eIF4E_1	594	600	PF01652	0.512
LIG_eIF4E_1	693	699	PF01652	0.603
LIG_FHA_1	1	7	PF00498	0.657
LIG_FHA_1	129	135	PF00498	0.576
LIG_FHA_1	182	188	PF00498	0.614
LIG_FHA_1	244	250	PF00498	0.491
LIG_FHA_1	288	294	PF00498	0.449
LIG_FHA_1	348	354	PF00498	0.393
LIG_FHA_1	478	484	PF00498	0.397
LIG_FHA_1	593	599	PF00498	0.590
LIG_FHA_1	77	83	PF00498	0.602
LIG_FHA_2	164	170	PF00498	0.552
LIG_FHA_2	230	236	PF00498	0.723
LIG_FHA_2	339	345	PF00498	0.424
LIG_FHA_2	45	51	PF00498	0.711
LIG_FHA_2	455	461	PF00498	0.404
LIG_LIR_Apic_2	198	202	PF02991	0.689
LIG_LIR_Gen_1	158	165	PF02991	0.643
LIG_LIR_Gen_1	393	403	PF02991	0.317
LIG_LIR_Gen_1	427	437	PF02991	0.415
LIG_LIR_Gen_1	450	459	PF02991	0.378
LIG_LIR_Gen_1	667	676	PF02991	0.607
LIG_LIR_Gen_1	690	701	PF02991	0.544
LIG_LIR_Nem_3	158	164	PF02991	0.642
LIG_LIR_Nem_3	270	276	PF02991	0.355
LIG_LIR_Nem_3	393	399	PF02991	0.316
LIG_LIR_Nem_3	427	433	PF02991	0.406
LIG_LIR_Nem_3	496	501	PF02991	0.324
LIG_LIR_Nem_3	624	628	PF02991	0.583
LIG_LIR_Nem_3	667	671	PF02991	0.598
LIG_LIR_Nem_3	690	696	PF02991	0.527
LIG_NRBOX	182	188	PF00104	0.619
LIG_NRBOX	398	404	PF00104	0.330
LIG_PDZ_Class_1	746	751	PF00595	0.639
LIG_Pex14_2	396	400	PF04695	0.359
LIG_PTB_Apo_2	652	659	PF02174	0.516
LIG_PTB_Phospho_1	652	658	PF10480	0.514
LIG_Rb_pABgroove_1	420	428	PF01858	0.322
LIG_RPA_C_Plants	716	727	PF08784	0.624
LIG_SH2_CRK	426	430	PF00017	0.333
LIG_SH2_CRK	501	505	PF00017	0.346
LIG_SH2_CRK	668	672	PF00017	0.541
LIG_SH2_GRB2like	452	455	PF00017	0.441
LIG_SH2_NCK_1	387	391	PF00017	0.296
LIG_SH2_NCK_1	430	434	PF00017	0.292
LIG_SH2_NCK_1	501	505	PF00017	0.363
LIG_SH2_NCK_1	668	672	PF00017	0.559
LIG_SH2_STAP1	426	430	PF00017	0.419
LIG_SH2_STAP1	594	598	PF00017	0.585
LIG_SH2_STAT5	12	15	PF00017	0.630
LIG_SH2_STAT5	452	455	PF00017	0.490
LIG_SH2_STAT5	594	597	PF00017	0.645
LIG_SH2_STAT5	636	639	PF00017	0.609
LIG_SH2_STAT5	69	72	PF00017	0.580
LIG_SH2_STAT5	693	696	PF00017	0.533
LIG_SH3_3	194	200	PF00018	0.663
LIG_SH3_3	254	260	PF00018	0.388
LIG_SH3_3	514	520	PF00018	0.308
LIG_SH3_3	55	61	PF00018	0.686
LIG_SH3_3	704	710	PF00018	0.650
LIG_SH3_3	93	99	PF00018	0.621
LIG_SH3_5	710	714	PF00018	0.677
LIG_SUMO_SIM_anti_2	184	191	PF11976	0.671
LIG_SUMO_SIM_anti_2	344	350	PF11976	0.440
LIG_SUMO_SIM_anti_2	595	601	PF11976	0.546
LIG_SUMO_SIM_par_1	130	135	PF11976	0.660
LIG_SUMO_SIM_par_1	184	191	PF11976	0.605
LIG_SUMO_SIM_par_1	253	259	PF11976	0.348
LIG_TRAF2_1	741	744	PF00917	0.641
LIG_TYR_ITIM	499	504	PF00017	0.381
LIG_TYR_ITIM	592	597	PF00017	0.457
LIG_TYR_ITSM	426	433	PF00017	0.279
LIG_UBA3_1	293	301	PF00899	0.621
LIG_UBA3_1	399	404	PF00899	0.458
LIG_UBA3_1	698	704	PF00899	0.588
MOD_CDC14_SPxK_1	307	310	PF00782	0.546
MOD_CDK_SPxK_1	304	310	PF00069	0.557
MOD_CDK_SPxxK_3	198	205	PF00069	0.513
MOD_CK1_1	201	207	PF00069	0.720
MOD_CK1_1	306	312	PF00069	0.718
MOD_CK1_1	365	371	PF00069	0.636
MOD_CK1_1	450	456	PF00069	0.586
MOD_CK1_1	581	587	PF00069	0.565
MOD_CK1_1	76	82	PF00069	0.601
MOD_CK2_1	132	138	PF00069	0.511
MOD_CK2_1	150	156	PF00069	0.594
MOD_CK2_1	163	169	PF00069	0.325
MOD_CK2_1	229	235	PF00069	0.668
MOD_CK2_1	338	344	PF00069	0.532
MOD_CK2_1	441	447	PF00069	0.387
MOD_CK2_1	467	473	PF00069	0.558
MOD_CK2_1	738	744	PF00069	0.542
MOD_DYRK1A_RPxSP_1	555	559	PF00069	0.634
MOD_GlcNHglycan	134	137	PF01048	0.451
MOD_GlcNHglycan	269	272	PF01048	0.449
MOD_GlcNHglycan	358	361	PF01048	0.648
MOD_GlcNHglycan	373	376	PF01048	0.561
MOD_GlcNHglycan	449	452	PF01048	0.662
MOD_GlcNHglycan	473	476	PF01048	0.492
MOD_GlcNHglycan	536	539	PF01048	0.674
MOD_GlcNHglycan	575	578	PF01048	0.658
MOD_GlcNHglycan	581	584	PF01048	0.691
MOD_GlcNHglycan	75	78	PF01048	0.502
MOD_GSK3_1	128	135	PF00069	0.504
MOD_GSK3_1	150	157	PF00069	0.647
MOD_GSK3_1	207	214	PF00069	0.713
MOD_GSK3_1	223	230	PF00069	0.522
MOD_GSK3_1	285	292	PF00069	0.567
MOD_GSK3_1	302	309	PF00069	0.667
MOD_GSK3_1	364	371	PF00069	0.578
MOD_GSK3_1	450	457	PF00069	0.495
MOD_GSK3_1	467	474	PF00069	0.314
MOD_GSK3_1	50	57	PF00069	0.572
MOD_GSK3_1	553	560	PF00069	0.638
MOD_GSK3_1	76	83	PF00069	0.477
MOD_N-GLC_1	592	597	PF02516	0.433
MOD_N-GLC_2	192	194	PF02516	0.603
MOD_NEK2_1	115	120	PF00069	0.624
MOD_NEK2_1	132	137	PF00069	0.361
MOD_NEK2_1	163	168	PF00069	0.559
MOD_NEK2_1	211	216	PF00069	0.556
MOD_NEK2_1	275	280	PF00069	0.531
MOD_NEK2_1	293	298	PF00069	0.599
MOD_NEK2_1	347	352	PF00069	0.472
MOD_NEK2_1	425	430	PF00069	0.363
MOD_NEK2_1	703	708	PF00069	0.552
MOD_NEK2_1	82	87	PF00069	0.553
MOD_NEK2_2	207	212	PF00069	0.609
MOD_NEK2_2	661	666	PF00069	0.481
MOD_PIKK_1	82	88	PF00454	0.497
MOD_PK_1	493	499	PF00069	0.462
MOD_PKA_1	151	157	PF00069	0.557
MOD_PKA_1	223	229	PF00069	0.686
MOD_PKA_1	24	30	PF00069	0.610
MOD_PKA_1	493	499	PF00069	0.462
MOD_PKA_1	553	559	PF00069	0.634
MOD_PKA_2	150	156	PF00069	0.589
MOD_PKA_2	211	217	PF00069	0.607
MOD_PKA_2	223	229	PF00069	0.635
MOD_PKA_2	24	30	PF00069	0.579
MOD_PKA_2	267	273	PF00069	0.572
MOD_PKA_2	44	50	PF00069	0.409
MOD_PKA_2	493	499	PF00069	0.379
MOD_PKA_2	554	560	PF00069	0.634
MOD_PKB_1	551	559	PF00069	0.730
MOD_Plk_1	155	161	PF00069	0.568
MOD_Plk_1	368	374	PF00069	0.555
MOD_Plk_1	468	474	PF00069	0.536
MOD_Plk_1	49	55	PF00069	0.673
MOD_Plk_1	592	598	PF00069	0.397
MOD_Plk_4	156	162	PF00069	0.450
MOD_Plk_4	181	187	PF00069	0.501
MOD_Plk_4	289	295	PF00069	0.602
MOD_Plk_4	425	431	PF00069	0.438
MOD_Plk_4	493	499	PF00069	0.368
MOD_Plk_4	62	68	PF00069	0.491
MOD_Plk_4	703	709	PF00069	0.505
MOD_Plk_4	8	14	PF00069	0.475
MOD_ProDKin_1	198	204	PF00069	0.622
MOD_ProDKin_1	215	221	PF00069	0.477
MOD_ProDKin_1	243	249	PF00069	0.448
MOD_ProDKin_1	256	262	PF00069	0.357
MOD_ProDKin_1	304	310	PF00069	0.595
MOD_ProDKin_1	516	522	PF00069	0.308
MOD_ProDKin_1	555	561	PF00069	0.632
MOD_ProDKin_1	60	66	PF00069	0.579
MOD_ProDKin_1	738	744	PF00069	0.622
MOD_SUMO_for_1	238	241	PF00179	0.616
MOD_SUMO_rev_2	675	683	PF00179	0.467
TRG_DiLeu_BaEn_2	419	425	PF01217	0.326
TRG_DiLeu_BaLyEn_6	694	699	PF01217	0.534
TRG_ENDOCYTIC_2	426	429	PF00928	0.392
TRG_ENDOCYTIC_2	430	433	PF00928	0.432
TRG_ENDOCYTIC_2	452	455	PF00928	0.536
TRG_ENDOCYTIC_2	501	504	PF00928	0.337
TRG_ENDOCYTIC_2	510	513	PF00928	0.349
TRG_ENDOCYTIC_2	594	597	PF00928	0.368
TRG_ENDOCYTIC_2	636	639	PF00928	0.505
TRG_ENDOCYTIC_2	668	671	PF00928	0.406
TRG_ENDOCYTIC_2	693	696	PF00928	0.404
TRG_ENDOCYTIC_2	729	732	PF00928	0.562
TRG_ER_diArg_1	283	285	PF00400	0.547
TRG_ER_diArg_1	461	464	PF00400	0.466
TRG_ER_diArg_1	492	494	PF00400	0.478
TRG_ER_diArg_1	544	546	PF00400	0.629
TRG_ER_diArg_1	551	553	PF00400	0.626
TRG_ER_diArg_1	567	569	PF00400	0.617
TRG_ER_diArg_1	613	615	PF00400	0.540
TRG_NES_CRM1_1	124	138	PF08389	0.461
TRG_NES_CRM1_1	344	354	PF08389	0.524
TRG_NLS_MonoExtN_4	223	228	PF00514	0.709
TRG_NLS_MonoExtN_4	551	557	PF00514	0.679
TRG_Pf-PMV_PEXEL_1	338	342	PF00026	0.573
TRG_Pf-PMV_PEXEL_1	611	616	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P427	Leptomonas seymouri	59%	100%
A0A3R7LDE0	Trypanosoma rangeli	36%	100%
A0A3S7X4C5	Leishmania donovani	94%	100%
A4HJ81	Leishmania braziliensis	77%	100%
A4I6M5	Leishmania infantum	93%	100%
D0A0I5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9B1P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
V5BX02	Trypanosoma cruzi	35%	100%