Methyltransf_25 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q95Z88_LEIMA

TriTrypDb:

LmjF.04.0070 , LMJLV39_040005800 , LMJSD75_040005800

Length:

245

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q95Z88

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q95Z88

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0008152	metabolic process	1	1
GO:0032259	methylation	2	1

Previous1Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0008168	methyltransferase activity	4	1
GO:0016740	transferase activity	2	1
GO:0016741	transferase activity, transferring one-carbon groups	3	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	18	20	PF00675	0.443
CLV_PCSK_KEX2_1	18	20	PF00082	0.410
CLV_PCSK_SKI1_1	209	213	PF00082	0.499
DOC_CYCLIN_RxL_1	59	68	PF00134	0.347
DOC_MAPK_gen_1	187	195	PF00069	0.318
DOC_MAPK_MEF2A_6	187	195	PF00069	0.318
DOC_WW_Pin1_4	237	242	PF00397	0.483
LIG_14-3-3_CanoR_1	18	26	PF00244	0.407
LIG_14-3-3_CanoR_1	209	217	PF00244	0.507
LIG_14-3-3_CanoR_1	233	238	PF00244	0.393

Previous1 2 3 4 5…9Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTY0	Leptomonas seymouri	69%	100%
A0A0S4IH71	Bodo saltans	42%	93%
A0A0S4IJP7	Bodo saltans	29%	100%
A0A0S4J8X8	Bodo saltans	41%	100%
A0A1X0NMV1	Trypanosomatidae	47%	100%
A0A3S5H574	Leishmania donovani	94%	100%
A0A422NN81	Trypanosoma rangeli	44%	100%
A4H3S8	Leishmania braziliensis	87%	100%
A4HS03	Leishmania infantum	93%	100%
C9ZY01	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%

Previous1 2Next