Elongation factor 1-alpha

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

elongation factor 1-alpha

Species:

Leishmania donovani

UniProt:

Q95VF2_LEIDO

TriTrypDb:

LdBPK_170170.1 , LdCL_170005900 , LdCL_170006000 , LdCL_170006100 , LdCL_170006200 , LdCL_170006300 , LdCL_170006400 , LdCL_170006500 , LdCL_170006600 , LdCL_170006700 , LdCL_170006800 , LdCL_170006900 , LDHU3_17.0110 , LDHU3_17.0120 , LDHU3_17.0130 , LDHU3_17.0140 , LDHU3_17.0150 , LDHU3_17.0160 , LDHU3_17.0170 , LDHU3_17.0180 , LDHU3_17.0190 , LDHU3_17.0210 , LDHU3_17.0240 , LDHU3_17.0270 , LDHU3_17.0290 , LDHU3_17.0300 , LDHU3_17.0310 , LDHU3_17.0330

Length:

449

Annotations

LeishMANIAdb interaction annotations

by homology
Contact email: ethan@interchange.ubc.ca
Publication title: Leishmania EF-1alpha Activates the Src Homology 2 Domain Containing Tyrosine Phosphatase SHP-1 Leading to Macrophage Deactivation
Publication 1st author(s): D. Nandan
Publication Identifier(s): 12384497
Host organism: Mus musculus
Interaction detection method(s): coimmunoprecipitation
Interaction type: direct interaction
Identification method participant A: western blot
Identification method participant B: predetermined participant
ID(s) interactor A: Q95VF2
ID(s) interactor B: P29350
Taxid interactor A: Leishmania donovani
Taxid interactor B: Mus musculus
Biological role(s) interactor A: enzyme target
Biological role(s) interactor B: enzyme
Experimental role(s) interactor A: prey

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 27

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 15
NetGPI	no	yes: 0, no: 15

Cellular components
Term	Name	Level	Count
GO:0018995	host cellular component	2	2
GO:0033643	host cell part	3	2
GO:0033646	host intracellular part	4	2
GO:0033655	host cell cytoplasm part	5	2
GO:0044164	host cell cytosol	6	2
GO:0110165	cellular anatomical entity	1	2

Phosphorylation

Amastigote: 53
Promastigote: 371

Expansion

Sequence features

Q95VF2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006414	translational elongation	5	4
GO:0008152	metabolic process	1	4
GO:0009058	biosynthetic process	2	4
GO:0009059	macromolecule biosynthetic process	4	4
GO:0009605	response to external stimulus	2	2
GO:0009607	response to biotic stimulus	2	2
GO:0009893	positive regulation of metabolic process	4	2
GO:0009987	cellular process	1	4
GO:0010562	positive regulation of phosphorus metabolic process	6	2
GO:0010604	positive regulation of macromolecule metabolic process	5	2
GO:0010921	regulation of phosphatase activity	5	2
GO:0010922	positive regulation of phosphatase activity	6	2
GO:0019220	regulation of phosphate metabolic process	6	2
GO:0019222	regulation of metabolic process	3	2
GO:0030682	mitigation of host defenses by symbiont	5	2
GO:0031323	regulation of cellular metabolic process	4	2
GO:0031325	positive regulation of cellular metabolic process	5	2
GO:0031347	regulation of defense response	5	2
GO:0031348	negative regulation of defense response	5	2
GO:0031399	regulation of protein modification process	6	2
GO:0031401	positive regulation of protein modification process	7	2
GO:0032516	positive regulation of phosphoprotein phosphatase activity	7	2
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	4
GO:0035303	regulation of dephosphorylation	7	2
GO:0035304	regulation of protein dephosphorylation	7	2
GO:0035306	positive regulation of dephosphorylation	8	2
GO:0035307	positive regulation of protein dephosphorylation	8	2
GO:0035821	modulation of process of another organism	2	2
GO:0043085	positive regulation of catalytic activity	4	2
GO:0043170	macromolecule metabolic process	3	4
GO:0043207	response to external biotic stimulus	3	2
GO:0043666	regulation of phosphoprotein phosphatase activity	6	2
GO:0044003	modulation by symbiont of host process	3	2
GO:0044093	positive regulation of molecular function	3	2
GO:0044237	cellular metabolic process	2	4
GO:0044249	cellular biosynthetic process	3	4
GO:0044260	obsolete cellular macromolecule metabolic process	3	4
GO:0044403	biological process involved in symbiotic interaction	2	2
GO:0044414	suppression of host defenses by symbiont	5	2
GO:0044419	biological process involved in interspecies interaction between organisms	1	2
GO:0045937	positive regulation of phosphate metabolic process	7	2
GO:0048518	positive regulation of biological process	3	2
GO:0048519	negative regulation of biological process	3	2
GO:0048522	positive regulation of cellular process	4	2
GO:0048583	regulation of response to stimulus	3	2
GO:0048585	negative regulation of response to stimulus	4	2
GO:0050789	regulation of biological process	2	2
GO:0050790	regulation of catalytic activity	3	2
GO:0050794	regulation of cellular process	3	2
GO:0050896	response to stimulus	1	2
GO:0051171	regulation of nitrogen compound metabolic process	4	2
GO:0051173	positive regulation of nitrogen compound metabolic process	5	2
GO:0051174	regulation of phosphorus metabolic process	5	2
GO:0051246	regulation of protein metabolic process	5	2
GO:0051247	positive regulation of protein metabolic process	6	2
GO:0051336	regulation of hydrolase activity	4	2
GO:0051345	positive regulation of hydrolase activity	5	2
GO:0051701	biological process involved in interaction with host	3	2
GO:0051707	response to other organism	2	2
GO:0052031	modulation by symbiont of host defense response	4	2
GO:0052173	response to defenses of other organism	3	2
GO:0052200	response to host defenses	4	2
GO:0060255	regulation of macromolecule metabolic process	4	2
GO:0065007	biological regulation	1	2
GO:0065009	regulation of molecular function	2	2
GO:0071704	organic substance metabolic process	2	4
GO:0075136	response to host	3	2
GO:0080090	regulation of primary metabolic process	4	2
GO:0080134	regulation of response to stress	4	2
GO:1901576	organic substance biosynthetic process	3	4
GO:1903613	regulation of protein tyrosine phosphatase activity	7	2
GO:1903615	positive regulation of protein tyrosine phosphatase activity	8	2
GO:0006412	translation	4	2
GO:0006518	peptide metabolic process	4	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0019538	protein metabolic process	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0043043	peptide biosynthetic process	5	2
GO:0043603	amide metabolic process	3	2
GO:0043604	amide biosynthetic process	4	2
GO:0044238	primary metabolic process	2	2
GO:0044271	cellular nitrogen compound biosynthetic process	4	2
GO:1901564	organonitrogen compound metabolic process	3	2
GO:1901566	organonitrogen compound biosynthetic process	4	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	16
GO:0003676	nucleic acid binding	3	16
GO:0003746	translation elongation factor activity	4	16
GO:0003824	catalytic activity	1	16
GO:0003924	GTPase activity	7	16
GO:0005488	binding	1	16
GO:0005515	protein binding	2	2
GO:0005516	calmodulin binding	3	2
GO:0005525	GTP binding	5	16
GO:0008135	translation factor activity, RNA binding	3	16
GO:0016462	pyrophosphatase activity	5	16
GO:0016787	hydrolase activity	2	16
GO:0016817	hydrolase activity, acting on acid anhydrides	3	16
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	16
GO:0017076	purine nucleotide binding	4	16
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	16
GO:0019001	guanyl nucleotide binding	5	16
GO:0019899	enzyme binding	3	2
GO:0019902	phosphatase binding	4	2
GO:0019903	protein phosphatase binding	5	2
GO:0032553	ribonucleotide binding	3	16
GO:0032555	purine ribonucleotide binding	4	16
GO:0032561	guanyl ribonucleotide binding	5	16
GO:0035639	purine ribonucleoside triphosphate binding	4	16
GO:0036094	small molecule binding	2	16
GO:0043167	ion binding	2	16
GO:0043168	anion binding	3	16
GO:0045182	translation regulator activity	1	16
GO:0090079	translation regulator activity, nucleic acid binding	2	16
GO:0097159	organic cyclic compound binding	2	16
GO:0097367	carbohydrate derivative binding	2	16
GO:1901265	nucleoside phosphate binding	3	16
GO:1901363	heterocyclic compound binding	2	16

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	107	111	PF00656	0.554
CLV_C14_Caspase3-7	203	207	PF00656	0.634
CLV_C14_Caspase3-7	215	219	PF00656	0.650
CLV_C14_Caspase3-7	88	92	PF00656	0.542
CLV_NRD_NRD_1	309	311	PF00675	0.344
CLV_NRD_NRD_1	369	371	PF00675	0.343
CLV_PCSK_KEX2_1	179	181	PF00082	0.452
CLV_PCSK_KEX2_1	309	311	PF00082	0.344
CLV_PCSK_KEX2_1	36	38	PF00082	0.345
CLV_PCSK_KEX2_1	369	371	PF00082	0.343
CLV_PCSK_PC1ET2_1	179	181	PF00082	0.431
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.342
CLV_PCSK_SKI1_1	158	162	PF00082	0.397
CLV_PCSK_SKI1_1	380	384	PF00082	0.341
CLV_PCSK_SKI1_1	445	449	PF00082	0.689
CLV_PCSK_SKI1_1	69	73	PF00082	0.348
CLV_PCSK_SKI1_1	84	88	PF00082	0.345
DEG_APCC_DBOX_1	234	242	PF00400	0.496
DOC_CYCLIN_yCln2_LP_2	223	229	PF00134	0.550
DOC_MAPK_gen_1	3	12	PF00069	0.422
DOC_MAPK_gen_1	415	425	PF00069	0.539
DOC_MAPK_gen_1	64	73	PF00069	0.542
DOC_MAPK_JIP1_4	232	238	PF00069	0.517
DOC_MAPK_MEF2A_6	3	12	PF00069	0.422
DOC_MAPK_MEF2A_6	418	425	PF00069	0.539
DOC_MAPK_MEF2A_6	67	75	PF00069	0.542
DOC_MAPK_NFAT4_5	5	13	PF00069	0.422
DOC_PP1_RVXF_1	185	191	PF00149	0.554
DOC_PP2B_LxvP_1	223	226	PF13499	0.535
DOC_PP2B_LxvP_1	234	237	PF13499	0.511
DOC_PP4_FxxP_1	80	83	PF00568	0.542
DOC_SPAK_OSR1_1	411	415	PF12202	0.539
DOC_USP7_MATH_1	18	22	PF00917	0.542
DOC_USP7_MATH_1	381	385	PF00917	0.586
DOC_USP7_UBL2_3	154	158	PF12436	0.555
DOC_USP7_UBL2_3	373	377	PF12436	0.543
DOC_USP7_UBL2_3	427	431	PF12436	0.539
DOC_USP7_UBL2_3	441	445	PF12436	0.566
DOC_USP7_UBL2_3	51	55	PF12436	0.544
DOC_WW_Pin1_4	79	84	PF00397	0.542
LIG_14-3-3_CanoR_1	418	422	PF00244	0.539
LIG_APCC_ABBA_1	280	285	PF00400	0.544
LIG_APCC_ABBA_1	400	405	PF00400	0.552
LIG_BIR_III_4	91	95	PF00653	0.542
LIG_eIF4E_1	211	217	PF01652	0.543
LIG_FHA_1	140	146	PF00498	0.544
LIG_FHA_1	22	28	PF00498	0.542
LIG_FHA_1	247	253	PF00498	0.388
LIG_FHA_1	272	278	PF00498	0.553
LIG_FHA_1	327	333	PF00498	0.544
LIG_FHA_1	351	357	PF00498	0.543
LIG_FHA_1	418	424	PF00498	0.539
LIG_FHA_1	70	76	PF00498	0.542
LIG_FHA_2	213	219	PF00498	0.552
LIG_FHA_2	86	92	PF00498	0.542
LIG_LIR_Gen_1	165	174	PF02991	0.556
LIG_LIR_Gen_1	53	63	PF02991	0.542
LIG_LIR_Gen_1	85	93	PF02991	0.543
LIG_LIR_Nem_3	165	170	PF02991	0.556
LIG_LIR_Nem_3	342	348	PF02991	0.631
LIG_LIR_Nem_3	401	406	PF02991	0.541
LIG_LIR_Nem_3	53	59	PF02991	0.542
LIG_LIR_Nem_3	85	90	PF02991	0.546
LIG_Pex14_2	54	58	PF04695	0.542
LIG_SH2_CRK	211	215	PF00017	0.543
LIG_SH2_CRK	345	349	PF00017	0.543
LIG_SH2_CRK	406	410	PF00017	0.540
LIG_SH2_NCK_1	167	171	PF00017	0.631
LIG_SH2_SRC	167	170	PF00017	0.543
LIG_SH2_SRC	345	348	PF00017	0.554
LIG_SH2_STAP1	56	60	PF00017	0.542
LIG_SH2_STAT5	177	180	PF00017	0.543
LIG_SH3_1	391	397	PF00018	0.541
LIG_SH3_3	223	229	PF00018	0.541
LIG_SH3_3	391	397	PF00018	0.541
LIG_SUMO_SIM_par_1	112	119	PF11976	0.543
LIG_WRC_WIRS_1	265	270	PF05994	0.544
MOD_CDK_SPK_2	79	84	PF00069	0.542
MOD_CK1_1	21	27	PF00069	0.547
MOD_CK1_1	82	88	PF00069	0.542
MOD_CK2_1	368	374	PF00069	0.542
MOD_GlcNHglycan	193	196	PF01048	0.388
MOD_GlcNHglycan	370	373	PF01048	0.343
MOD_GlcNHglycan	383	386	PF01048	0.343
MOD_GlcNHglycan	433	437	PF01048	0.552
MOD_GSK3_1	158	165	PF00069	0.615
MOD_GSK3_1	272	279	PF00069	0.544
MOD_N-GLC_1	271	276	PF02516	0.344
MOD_N-GLC_1	301	306	PF02516	0.344
MOD_N-GLC_2	312	314	PF02516	0.355
MOD_NEK2_1	115	120	PF00069	0.633
MOD_NEK2_1	139	144	PF00069	0.544
MOD_NEK2_1	417	422	PF00069	0.539
MOD_NEK2_2	50	55	PF00069	0.542
MOD_PIKK_1	104	110	PF00454	0.543
MOD_PK_1	301	307	PF00069	0.544
MOD_PKA_2	368	374	PF00069	0.543
MOD_PKA_2	417	423	PF00069	0.539
MOD_PKB_1	67	75	PF00069	0.542
MOD_Plk_1	156	162	PF00069	0.555
MOD_Plk_1	301	307	PF00069	0.544
MOD_Plk_2-3	276	282	PF00069	0.544
MOD_Plk_2-3	35	41	PF00069	0.542
MOD_Plk_4	212	218	PF00069	0.564
MOD_Plk_4	82	88	PF00069	0.546
MOD_ProDKin_1	79	85	PF00069	0.542
MOD_SUMO_for_1	63	66	PF00179	0.542
MOD_SUMO_rev_2	362	367	PF00179	0.552
TRG_DiLeu_BaEn_2	185	191	PF01217	0.554
TRG_ENDOCYTIC_2	167	170	PF00928	0.543
TRG_ENDOCYTIC_2	345	348	PF00928	0.543
TRG_ENDOCYTIC_2	406	409	PF00928	0.541
TRG_ENDOCYTIC_2	56	59	PF00928	0.543
TRG_ER_diArg_1	308	310	PF00400	0.544

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Q3	Leptomonas seymouri	28%	96%
A0A0N1I5B5	Leptomonas seymouri	35%	69%
A0A0S4IUT7	Bodo saltans	82%	100%
A0A0S4IX91	Bodo saltans	35%	67%
A0A0S4J558	Bodo saltans	29%	96%
A0A0S4JRG2	Bodo saltans	84%	100%
A0A1X0NXE4	Trypanosomatidae	93%	100%
A0A1X0NXE5	Trypanosomatidae	94%	100%
A0A1X0P591	Trypanosomatidae	34%	67%
A0A1X0P746	Trypanosomatidae	29%	96%
A0A1X0PAN1	Trypanosomatidae	25%	68%
A0A3R7MLL0	Trypanosoma rangeli	37%	68%
A0A3S5IRQ8	Trypanosoma rangeli	24%	72%
A0A3S7WV40	Leishmania donovani	29%	96%
A0A3S7X9T0	Leishmania donovani	34%	70%
A0A422NIJ1	Trypanosoma rangeli	92%	100%
A0A422NK97	Trypanosoma rangeli	34%	68%
A0A422P1Y0	Trypanosoma rangeli	29%	96%
A0B7D6	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	53%	100%
A0JZ88	Arthrobacter sp. (strain FB24)	31%	100%
A0KP35	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	29%	95%
A0L5V8	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	28%	100%
A0LRL8	Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B)	29%	100%
A0PM42	Mycobacterium ulcerans (strain Agy99)	30%	100%
A0Q6F0	Francisella tularensis subsp. novicida (strain U112)	29%	96%
A0QL35	Mycobacterium avium (strain 104)	29%	100%
A0QS98	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	30%	100%
A0R8H8	Bacillus thuringiensis (strain Al Hakam)	30%	100%
A0RQJ3	Campylobacter fetus subsp. fetus (strain 82-40)	28%	100%
A0RUM4	Cenarchaeum symbiosum (strain A)	51%	100%
A1AEU5	Escherichia coli O1:K1 / APEC	35%	95%
A1ALS6	Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)	30%	100%
A1JJT0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	32%	94%
A1KGG5	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	30%	100%
A1R8U9	Paenarthrobacter aurescens (strain TC1)	31%	100%
A1RRJ3	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	52%	100%
A1RXW9	Thermofilum pendens (strain DSM 2475 / Hrk 5)	53%	100%
A1ST27	Psychromonas ingrahamii (strain 37)	32%	96%
A1T4L6	Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1)	30%	100%
A1VAK4	Desulfovibrio vulgaris subsp. vulgaris (strain DP4)	31%	100%
A2BN41	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	56%	100%
A2CI56	Chlorokybus atmophyticus	30%	100%
A2Q0Z0	Equus caballus	75%	97%
A2STF0	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	54%	100%
A3CTG3	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	53%	100%
A3DJ00	Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)	30%	100%
A3DMQ1	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	57%	100%
A3MV69	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	51%	100%
A4FWE9	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	53%	100%
A4H6P3	Leishmania braziliensis	36%	69%
A4H8V4	Leishmania braziliensis	95%	100%
A4H9I5	Leishmania braziliensis	28%	100%
A4HN87	Leishmania braziliensis	34%	100%
A4HX73	Leishmania infantum	100%	100%
A4IBV5	Leishmania infantum	34%	100%
A4IJI7	Geobacillus thermodenitrificans (strain NG80-2)	29%	100%
A4IXZ5	Francisella tularensis subsp. tularensis (strain WY96-3418)	29%	96%
A4SRG8	Aeromonas salmonicida (strain A449)	29%	95%
A4WKK8	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	51%	100%
A4XI37	Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)	32%	100%
A4YCR6	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	56%	100%
A5CCA0	Orientia tsutsugamushi (strain Boryong)	31%	100%
A5CCL4	Orientia tsutsugamushi (strain Boryong)	31%	100%
A5CUB6	Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382)	31%	100%
A5D5I8	Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)	30%	100%
A5D5K0	Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)	30%	100%
A5DPE3	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	75%	98%
A5F578	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	32%	94%
A5FIJ9	Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101)	29%	100%
A5FZW7	Acidiphilium cryptum (strain JF-5)	30%	100%
A5GAW4	Geotalea uraniireducens (strain Rf4)	30%	100%
A5I7K8	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	30%	100%
A5IM81	Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1)	31%	100%
A5N4N1	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	31%	100%
A5U071	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	30%	100%
A5ULM5	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	50%	100%
A5V604	Rhizorhabdus wittichii (strain DSM 6014 / CCUG 31198 / JCM 15750 / NBRC 105917 / EY 4224 / RW1)	30%	100%
A6GYU7	Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86)	29%	100%
A6LE88	Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)	28%	100%
A6LLL1	Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429)	30%	100%
A6LPP6	Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)	31%	100%
A6Q1L5	Nitratiruptor sp. (strain SB155-2)	30%	100%
A6QB12	Sulfurovum sp. (strain NBC37-1)	30%	94%
A6UQ14	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	53%	100%
A6UV43	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	53%	100%
A6VGV6	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	53%	100%
A6W5T5	Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)	30%	100%
A7FLY2	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	32%	94%
A7FZ71	Clostridium botulinum (strain ATCC 19397 / Type A)	30%	100%
A7GJ76	Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)	30%	100%
A7GK18	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	29%	100%
A7GZK6	Campylobacter curvus (strain 525.92)	28%	100%
A7HBL7	Anaeromyxobacter sp. (strain Fw109-5)	31%	100%
A7HM54	Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1)	31%	100%
A7I3U7	Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A)	31%	100%
A7I656	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	54%	100%
A7MJ69	Cronobacter sakazakii (strain ATCC BAA-894)	35%	95%
A7MWE9	Vibrio campbellii (strain ATCC BAA-1116)	32%	94%
A7ZCN0	Campylobacter concisus (strain 13826)	28%	100%
A7ZQJ5	Escherichia coli O139:H28 (strain E24377A / ETEC)	34%	95%
A8A3N0	Escherichia coli O9:H4 (strain HS)	35%	95%
A8ABM5	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	57%	100%
A8ANW5	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	30%	95%
A8EWR6	Aliarcobacter butzleri (strain RM4018)	28%	96%
A8EZL8	Rickettsia canadensis (strain McKiel)	29%	100%
A8F2E9	Rickettsia massiliae (strain Mtu5)	30%	100%
A8F4Q9	Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO)	33%	100%
A8GPF2	Rickettsia akari (strain Hartford)	31%	100%
A8GT71	Rickettsia rickettsii (strain Sheila Smith)	30%	100%
A8MAJ1	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	50%	100%
A8Z5T8	Sulcia muelleri (strain GWSS)	30%	100%
A9A9U3	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	53%	100%
A9BHA7	Petrotoga mobilis (strain DSM 10674 / SJ95)	31%	100%
A9H3R7	Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 / PAl5)	29%	100%
A9MF24	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	34%	94%
A9N2D8	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	29%	94%
A9VP75	Bacillus mycoides (strain KBAB4)	30%	100%
A9WSW5	Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)	30%	100%
B0BUR2	Rickettsia rickettsii (strain Iowa)	30%	100%
B0R8C3	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	51%	100%
B0RB36	Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1)	31%	100%
B0TC54	Heliobacterium modesticaldum (strain ATCC 51547 / Ice1)	31%	100%
B1AJG3	Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736)	31%	100%
B1IGF6	Clostridium botulinum (strain Okra / Type B1)	30%	100%
B1IUS8	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	34%	95%
B1KMH4	Shewanella woodyi (strain ATCC 51908 / MS32)	33%	96%
B1KSM7	Clostridium botulinum (strain Loch Maree / Type A3)	30%	100%
B1LBP2	Thermotoga sp. (strain RQ2)	31%	100%
B1LQ72	Escherichia coli (strain SMS-3-5 / SECEC)	35%	95%
B1XCS7	Escherichia coli (strain K12 / DH10B)	35%	95%
B2GIL2	Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)	31%	100%
B2HSL3	Mycobacterium marinum (strain ATCC BAA-535 / M)	30%	100%
B2J5B1	Nostoc punctiforme (strain ATCC 29133 / PCC 73102)	30%	100%
B2TZI0	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	34%	95%
B2VG01	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	32%	94%
B3E156	Methylacidiphilum infernorum (isolate V4)	31%	100%
B3PII1	Cellvibrio japonicus (strain Ueda107)	34%	95%
B3QY22	Chloroherpeton thalassium (strain ATCC 35110 / GB-78)	30%	100%
B3QZH5	Phytoplasma mali (strain AT)	30%	100%
B4T461	Salmonella newport (strain SL254)	29%	94%
B4TFX1	Salmonella heidelberg (strain SL476)	33%	94%
B4TTW5	Salmonella schwarzengrund (strain CVM19633)	29%	94%
B5BEY8	Salmonella paratyphi A (strain AKU_12601)	33%	94%
B5F415	Salmonella agona (strain SL483)	29%	94%
B5FGJ9	Aliivibrio fischeri (strain MJ11)	30%	94%
B5FTS9	Salmonella dublin (strain CT_02021853)	29%	94%
B5QW22	Salmonella enteritidis PT4 (strain P125109)	29%	94%
B5RDQ7	Salmonella gallinarum (strain 287/91 / NCTC 13346)	29%	94%
B5Z3B3	Escherichia coli O157:H7 (strain EC4115 / EHEC)	35%	95%
B5ZC31	Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)	31%	100%
B6ELP3	Aliivibrio salmonicida (strain LFI1238)	32%	94%
B6I6E1	Escherichia coli (strain SE11)	34%	95%
B6YVG2	Thermococcus onnurineus (strain NA1)	53%	100%
B7GJ65	Anoxybacillus flavithermus (strain DSM 21510 / WK1)	29%	100%
B7HJ46	Bacillus cereus (strain B4264)	30%	100%
B7HQU2	Bacillus cereus (strain AH187)	30%	100%
B7IHU4	Thermosipho africanus (strain TCF52B)	31%	100%
B7IT17	Bacillus cereus (strain G9842)	30%	100%
B7JKB7	Bacillus cereus (strain AH820)	30%	100%
B7LEG9	Escherichia coli (strain 55989 / EAEC)	34%	95%
B7LWK4	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	33%	95%
B7LXG3	Escherichia coli O8 (strain IAI1)	34%	95%
B7MKM5	Escherichia coli O45:K1 (strain S88 / ExPEC)	35%	95%
B7MZ52	Escherichia coli O81 (strain ED1a)	35%	95%
B7N6Y1	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	35%	95%
B7NT95	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	35%	95%
B7UHH0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	35%	95%
B8D7V3	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)	28%	95%
B8D9K1	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)	28%	95%
B8DLL9	Desulfovibrio vulgaris (strain DSM 19637 / Miyazaki F)	31%	100%
B8G1W4	Desulfitobacterium hafniense (strain DSM 10664 / DCB-2)	31%	100%
B8GIQ3	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	54%	100%
B8HD11	Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6)	31%	100%
B8HVR7	Cyanothece sp. (strain PCC 7425 / ATCC 29141)	29%	100%
B8J1A0	Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB)	31%	100%
B9IZJ2	Bacillus cereus (strain Q1)	30%	100%
B9K884	Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)	30%	100%
B9KFF9	Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060)	28%	100%
B9MQH1	Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320)	32%	100%
C0PXB1	Salmonella paratyphi C (strain RKS4594)	29%	94%
C0Q9Y7	Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2)	30%	100%
C0ZIH6	Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)	30%	100%
C1AL18	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	30%	100%
C1D890	Laribacter hongkongensis (strain HLHK9)	28%	93%
C1ET37	Bacillus cereus (strain 03BB102)	30%	100%
C3LJ80	Bacillus anthracis (strain CDC 684 / NRRL 3495)	30%	100%
C3LRM1	Vibrio cholerae serotype O1 (strain M66-2)	32%	94%
C3P9Q3	Bacillus anthracis (strain A0248)	30%	100%
C3PPA9	Rickettsia africae (strain ESF-5)	30%	100%
C4K2I2	Rickettsia peacockii (strain Rustic)	30%	100%
C4LAG3	Tolumonas auensis (strain DSM 9187 / TA4)	31%	95%
C4LL63	Corynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717)	30%	100%
C4ZZQ5	Escherichia coli (strain K12 / MC4100 / BW2952)	35%	95%
C5A5P4	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	53%	100%
C5BSJ5	Teredinibacter turnerae (strain ATCC 39867 / T7901)	30%	96%
C5C0J3	Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)	35%	100%
C5CC66	Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230)	30%	100%
C5CGR6	Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1)	30%	100%
C6A4R7	Thermococcus sibiricus (strain DSM 12597 / MM 739)	53%	100%
C9ZM43	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	69%
C9ZYQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	73%
C9ZZV6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	96%
D0A1M7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	92%	100%
D0A1M9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	89%	100%
E9AFP2	Leishmania major	35%	100%
E9AGP5	Leishmania infantum	100%	100%
E9AGP7	Leishmania infantum	88%	100%
E9AGQ3	Leishmania infantum	29%	100%
E9ARD0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9ARD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9ARL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B6U5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
O07309	Rhizobium sp. (strain BR816)	30%	71%
O21245	Reclinomonas americana	30%	100%
O24534	Vicia faba	77%	100%
O27132	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	52%	100%
O29325	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	55%	100%
O33581	Rhizobium tropici	32%	91%
O42820	Schizophyllum commune	77%	98%
O49169	Manihot esculenta	78%	100%
O50274	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	29%	71%
O50293	Aquifex pyrophilus	33%	100%
O50306	Geobacillus stearothermophilus	30%	100%
O50340	Fervidobacterium islandicum	32%	100%
O59153	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	54%	100%
O59949	Yarrowia lipolytica (strain CLIB 122 / E 150)	75%	98%
O64937	Oryza sativa subsp. japonica	77%	100%
O66429	Aquifex aeolicus (strain VF5)	33%	100%
O74718	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	68%
O74774	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	76%
O93729	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	52%	100%
P02992	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P02993	Artemia salina	72%	97%
P02994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	75%	98%
P05303	Drosophila melanogaster	73%	97%
P06805	Mucor circinelloides f. lusitanicus	75%	98%
P07810	Methanococcus vannielii	53%	100%
P08736	Drosophila melanogaster	75%	97%
P09953	Micrococcus luteus	31%	100%
P0A3A9	Rickettsia rickettsii	30%	100%
P0A3B0	Rickettsia sibirica	30%	100%
P0A559	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	30%	100%
P0CN30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	75%	98%
P0CN31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	75%	98%
P0CT31	Dictyostelium discoideum	73%	99%
P0CT32	Dictyostelium discoideum	73%	99%
P0CT53	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	74%	98%
P0CT54	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	74%	98%
P0CT55	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	74%	98%
P0CY35	Candida albicans (strain SC5314 / ATCC MYA-2876)	76%	98%
P0DH99	Arabidopsis thaliana	76%	100%
P10126	Mus musculus	76%	97%
P13442	Rhizobium meliloti (strain 1021)	31%	70%
P13537	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	31%	100%
P13549	Xenopus laevis	75%	97%
P14864	Mucor circinelloides f. lusitanicus	75%	98%
P14865	Mucor circinelloides f. lusitanicus	75%	98%
P14963	Euglena gracilis	82%	100%
P15170	Homo sapiens	39%	90%
P16018	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	50%	100%
P17196	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	53%	100%
P17197	Thermococcus celer	52%	100%
P17506	Xenopus laevis	63%	97%
P17507	Xenopus laevis	75%	97%
P17508	Xenopus laevis	75%	97%
P17786	Solanum lycopersicum	77%	100%
P19039	Apis mellifera	73%	97%
P19486	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	55%	100%
P22679	Metamycoplasma hominis (strain ATCC 23114 / DSM 25592 / NBRC 14850 / NCTC 10111 / PG21)	29%	100%
P23845	Escherichia coli (strain K12)	35%	95%
P25166	Stylonychia lemnae	77%	100%
P25698	Glycine max	78%	100%
P26751	Pyrococcus woesei	53%	100%
P27592	Onchocerca volvulus	71%	97%
P27634	Rhynchosciara americana	71%	100%
P28295	Absidia glauca	75%	98%
P29520	Bombyx mori	74%	97%
P29521	Daucus carota	77%	100%
P29544	Streptomyces ramocissimus	31%	100%
P31018	Entamoeba histolytica	72%	100%
P32186	Puccinia graminis	75%	97%
P32769	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	73%
P34823	Daucus carota	77%	100%
P34824	Hordeum vulgare	77%	100%
P34825	Hypocrea jecorina	75%	98%
P35021	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	55%	100%
P40175	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	32%	100%
P40911	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	74%	98%
P41203	Desulfurococcus mucosus	57%	100%
P41745	Blastobotrys adeninivorans	73%	98%
P41752	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	75%	98%
P42473	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	32%	100%
P42475	Fibrobacter succinogenes (strain ATCC 19169 / S85)	29%	100%
P42477	Herpetosiphon aurantiacus	30%	100%
P42479	Stigmatella aurantiaca	30%	100%
P43643	Nicotiana tabacum	77%	100%
P48865	Rickettsia prowazekii (strain Madrid E)	30%	100%
P49410	Bos taurus	33%	99%
P49411	Homo sapiens	31%	99%
P50068	Ureaplasma parvum serovar 3 (strain ATCC 700970)	31%	100%
P50256	Porphyra purpurea	75%	100%
P50257	Porphyra purpurea	57%	87%
P51554	Hydra vulgaris	71%	96%
P52978	Rhizobium tropici	27%	71%
P53013	Caenorhabditis elegans	73%	97%
P54959	Blastocystis hominis	73%	100%
P56893	Rhizobium meliloti (strain 1021)	33%	90%
P57498	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	28%	95%
P60338	Thermus thermophilus	33%	100%
P60339	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	33%	100%
P62629	Cricetulus griseus	76%	97%
P62630	Rattus norvegicus	76%	97%
P62631	Mus musculus	75%	97%
P62632	Rattus norvegicus	75%	97%
P68103	Bos taurus	76%	97%
P68104	Homo sapiens	76%	97%
P68105	Oryctolagus cuniculus	76%	97%
P72339	Rhizobium sp. (strain N33)	29%	70%
P84315	Heliothis virescens	74%	100%
P84316	Helicoverpa zea	74%	100%
P84317	Helicoverpa armigera	74%	100%
P84318	Helicoverpa gelotopoeon	74%	100%
P84319	Heliocheilus albipunctella	74%	100%
P84320	Heliocheilus discalis	74%	100%
P84321	Adisura bella	74%	100%
P84322	Anicla infecta	74%	100%
P85834	Rattus norvegicus	32%	99%
P86933	Trypanosoma brucei brucei	92%	100%
P86934	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	92%	100%
P86939	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	92%	100%
P90519	Cryptosporidium parvum	74%	100%
P9WNM4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	32%	73%
P9WNM5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	32%	73%
P9WNN0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	30%	100%
P9WNN1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	30%	100%
Q00080	Plasmodium falciparum (isolate K1 / Thailand)	69%	100%
Q00251	Aureobasidium pullulans	75%	98%
Q01372	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	75%	98%
Q01520	Podospora anserina	75%	98%
Q01698	Thermus aquaticus	32%	100%
Q01765	Podospora curvicolla	74%	97%
Q03033	Triticum aestivum	77%	100%
Q03YI2	Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)	31%	100%
Q04634	Tetrahymena pyriformis	76%	100%
Q04B37	Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365 / Lb-18)	31%	100%
Q05639	Homo sapiens	75%	97%
Q06J54	Bigelowiella natans	29%	100%
Q07051	Eimeria bovis	71%	100%
Q08046	Giardia intestinalis	65%	100%
Q09069	Sordaria macrospora	75%	98%
Q0BUQ2	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	29%	100%
Q0SQC8	Clostridium perfringens (strain SM101 / Type A)	30%	100%
Q0T1I2	Shigella flexneri serotype 5b (strain 8401)	33%	95%
Q0TEA7	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	35%	95%
Q0TMN0	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	30%	100%
Q0W8G2	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	49%	100%
Q0WL56	Arabidopsis thaliana	76%	100%
Q12WT3	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	52%	100%
Q134R0	Rhodopseudomonas palustris (strain BisB5)	29%	100%
Q134S7	Rhodopseudomonas palustris (strain BisB5)	29%	100%
Q149F3	Mus musculus	38%	71%
Q14HG2	Francisella tularensis subsp. tularensis (strain FSC 198)	29%	96%
Q18CE4	Clostridioides difficile (strain 630)	31%	100%
Q18EY5	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	50%	100%
Q1D776	Myxococcus xanthus (strain DK1622)	30%	100%
Q1D7V1	Myxococcus xanthus (strain DK1622)	30%	100%
Q1GAQ0	Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14)	31%	100%
Q1GP97	Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)	31%	100%
Q1IX70	Deinococcus geothermalis (strain DSM 11300 / AG-3a)	30%	100%
Q1KVS9	Tetradesmus obliquus	30%	100%
Q1MPT8	Lawsonia intracellularis (strain PHE/MN1-00)	31%	100%
Q1QN32	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	30%	100%
Q1QUF9	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	31%	95%
Q1R7U0	Escherichia coli (strain UTI89 / UPEC)	35%	95%
Q21IS6	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	30%	95%
Q250N4	Desulfitobacterium hafniense (strain Y51)	31%	100%
Q26487	Spodoptera frugiperda	74%	100%
Q27139	Euplotes crassus	70%	100%
Q27140	Euplotes crassus	60%	100%
Q2EEV7	Helicosporidium sp. subsp. Simulium jonesii	31%	100%
Q2FRI3	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	54%	100%
Q2G8Y2	Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)	30%	100%
Q2GFN6	Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)	30%	100%
Q2GJ61	Anaplasma phagocytophilum (strain HZ)	31%	100%
Q2HJN4	Oscheius tipulae	73%	98%
Q2HJN6	Oscheius tipulae	74%	98%
Q2HJN8	Oscheius tipulae	73%	98%
Q2HJN9	Oscheius tipulae	73%	98%
Q2JUX4	Synechococcus sp. (strain JA-3-3Ab)	29%	100%
Q2N9A8	Erythrobacter litoralis (strain HTCC2594)	29%	100%
Q2NEL1	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	50%	100%
Q2NJ20	Aster yellows witches'-broom phytoplasma (strain AYWB)	31%	100%
Q2NVM8	Sodalis glossinidius (strain morsitans)	32%	95%
Q2NZX1	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	31%	100%
Q2RFP5	Moorella thermoacetica (strain ATCC 39073 / JCM 9320)	30%	100%
Q2S1P8	Salinibacter ruber (strain DSM 13855 / M31)	29%	100%
Q2W2H3	Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)	30%	100%
Q30X13	Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)	31%	100%
Q31XB3	Shigella boydii serotype 4 (strain Sb227)	34%	95%
Q32CH9	Shigella dysenteriae serotype 1 (strain Sd197)	34%	95%
Q32PH8	Bos taurus	75%	97%
Q33451	Eimeria tenella	29%	100%
Q39Y08	Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15)	30%	100%
Q3A9P8	Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)	31%	100%
Q3A9R3	Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)	31%	100%
Q3BWY6	Xanthomonas campestris pv. vesicatoria (strain 85-10)	32%	100%
Q3IUD8	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	51%	100%
Q3SSW8	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	29%	100%
Q3YRK7	Ehrlichia canis (strain Jake)	30%	100%
Q3YYB1	Shigella sonnei (strain Ss046)	35%	95%
Q40034	Hordeum vulgare	78%	100%
Q41011	Pisum sativum	75%	100%
Q41803	Zea mays	77%	100%
Q464Z4	Methanosarcina barkeri (strain Fusaro / DSM 804)	51%	100%
Q47LJ1	Thermobifida fusca (strain YX)	29%	100%
Q482Z9	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	32%	96%
Q4MYA4	Theileria parva	30%	100%
Q4QDW8	Leishmania major	28%	100%
Q4QEI8	Leishmania major	99%	100%
Q4QEI9	Leishmania major	100%	100%
Q54HB2	Dictyostelium discoideum	31%	100%
Q57770	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	56%	100%
Q57KJ0	Salmonella choleraesuis (strain SC-B67)	29%	94%
Q59QD6	Candida albicans (strain SC5314 / ATCC MYA-2876)	76%	98%
Q5E830	Aliivibrio fischeri (strain ATCC 700601 / ES114)	31%	94%
Q5FFE6	Ehrlichia ruminantium (strain Gardel)	31%	100%
Q5GWR8	Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)	31%	100%
Q5HAS0	Ehrlichia ruminantium (strain Welgevonden)	31%	100%
Q5JFZ4	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	53%	100%
Q5L3Z9	Geobacillus kaustophilus (strain HTA426)	30%	100%
Q5LES3	Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow)	31%	94%
Q5NG10	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	29%	96%
Q5NQ65	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	31%	100%
Q5PBH1	Anaplasma marginale (strain St. Maries)	32%	100%
Q5PEH2	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	33%	94%
Q5R1X2	Pan troglodytes	76%	97%
Q5R4B3	Pongo abelii	38%	71%
Q5R4R8	Pongo abelii	76%	97%
Q5SHN6	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	33%	100%
Q5VTE0	Homo sapiens	75%	97%
Q5YPG4	Nocardia farcinica (strain IFM 10152)	30%	100%
Q605B0	Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)	30%	100%
Q63H92	Bacillus cereus (strain ZK / E33L)	30%	100%
Q64VQ9	Bacteroides fragilis (strain YCH46)	31%	94%
Q66EC7	Yersinia pseudotuberculosis serotype I (strain IP32953)	32%	94%
Q66RN5	Felis catus	76%	97%
Q67JU1	Symbiobacterium thermophilum (strain T / IAM 14863)	31%	100%
Q6A6L7	Cutibacterium acnes (strain DSM 16379 / KPA171202)	30%	100%
Q6ACZ0	Leifsonia xyli subsp. xyli (strain CTCB07)	31%	100%
Q6AP73	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	31%	100%
Q6AP86	Desulfotalea psychrophila (strain LSv54 / DSM 12343)	31%	100%
Q6AXM7	Rattus norvegicus	42%	66%
Q6FF97	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	30%	100%
Q6HPR0	Bacillus thuringiensis subsp. konkukian (strain 97-27)	30%	100%
Q6L202	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	53%	100%
Q6LM69	Photobacterium profundum (strain SS9)	31%	94%
Q6LXI1	Methanococcus maripaludis (strain S2 / LL)	53%	100%
Q6YQV8	Onion yellows phytoplasma (strain OY-M)	30%	100%
Q71V39	Oryctolagus cuniculus	75%	97%
Q727D5	Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough)	31%	100%
Q72GW4	Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)	33%	100%
Q73F98	Bacillus cereus (strain ATCC 10987 / NRS 248)	30%	100%
Q73SD1	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	29%	100%
Q748X8	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	30%	100%
Q74MI6	Nanoarchaeum equitans (strain Kin4-M)	48%	100%
Q7MPF2	Vibrio vulnificus (strain YJ016)	33%	94%
Q7N8L0	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	34%	94%
Q7NVN5	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	29%	94%
Q7UMW2	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	33%	69%
Q7YZN9	Dictyostelium discoideum	36%	81%
Q814C4	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	30%	100%
Q81VT2	Bacillus anthracis	30%	100%
Q826Z7	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	31%	100%
Q83GW1	Tropheryma whipplei (strain Twist)	30%	100%
Q83JX8	Shigella flexneri	34%	95%
Q83NT9	Tropheryma whipplei (strain TW08/27)	30%	100%
Q87DG7	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	30%	72%
Q87SX9	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	32%	94%
Q8AAP9	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)	31%	93%
Q8BFR5	Mus musculus	32%	99%
Q8DE73	Vibrio vulnificus (strain CMCP6)	33%	94%
Q8EB10	Shewanella oneidensis (strain MR-1)	30%	93%
Q8EX18	Malacoplasma penetrans (strain HF-2)	31%	100%
Q8FEJ1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	35%	95%
Q8GTY0	Arabidopsis thaliana	76%	100%
Q8IYD1	Homo sapiens	38%	71%
Q8KAH0	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	31%	100%
Q8KT95	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	29%	100%
Q8KT97	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	29%	100%
Q8KT99	Rickettsia helvetica	30%	100%
Q8KTA1	Rickettsia montanensis	29%	100%
Q8KTA6	Rickettsia parkeri	29%	100%
Q8LPC4	Neopyropia yezoensis	75%	100%
Q8NL22	Xanthomonas axonopodis pv. citri (strain 306)	32%	100%
Q8PUR8	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	51%	100%
Q8R050	Mus musculus	39%	71%
Q8R603	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	29%	100%
Q8SS29	Encephalitozoon cuniculi (strain GB-M1)	36%	95%
Q8TRC4	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	51%	100%
Q8TYP6	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	50%	100%
Q8U152	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	54%	100%
Q8UH69	Agrobacterium fabrum (strain C58 / ATCC 33970)	32%	91%
Q8W4H7	Arabidopsis thaliana	76%	100%
Q8X7X7	Escherichia coli O157:H7	35%	95%
Q8XFP8	Clostridium perfringens (strain 13 / Type A)	30%	100%
Q8Z470	Salmonella typhi	33%	94%
Q8ZBP2	Yersinia pestis	32%	94%
Q8ZMF5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	29%	94%
Q90835	Gallus gallus	76%	97%
Q92005	Danio rerio	77%	97%
Q92GW4	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	30%	100%
Q96WZ1	Coccidioides immitis (strain RS)	74%	98%
Q976B1	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	54%	100%
Q979T1	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	54%	100%
Q98QG1	Mycoplasmopsis pulmonis (strain UAB CTIP)	29%	100%
Q99QM0	Caulobacter vibrioides (strain ATCC 19089 / CB15)	30%	100%
Q9HDF6	Serendipita indica	75%	97%
Q9HGI4	Zygosaccharomyces rouxii	39%	68%
Q9HM89	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	51%	100%
Q9KP20	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	32%	94%
Q9P9Q9	Xylella fastidiosa (strain 9a5c)	31%	100%
Q9PD78	Xylella fastidiosa (strain 9a5c)	30%	72%
Q9TJQ8	Prototheca wickerhamii	31%	100%
Q9V0V7	Pyrococcus abyssi (strain GE5 / Orsay)	53%	100%
Q9W074	Drosophila melanogaster	37%	67%
Q9Y713	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	74%	98%
Q9YAV0	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	56%	100%
Q9YIC0	Oryzias latipes	75%	97%
Q9ZEU3	Apple proliferation phytoplasma	30%	100%
Q9ZT91	Arabidopsis thaliana	31%	99%
V5BQE1	Trypanosoma cruzi	24%	72%
V5BT94	Trypanosoma cruzi	35%	68%
V5BWI6	Trypanosoma cruzi	37%	89%
V5DN37	Trypanosoma cruzi	29%	96%