LeishMANIAdb
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Guanine nucleotide-binding protein subunit beta-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Guanine nucleotide-binding protein subunit beta-like protein
Gene product:
activated protein kinase c receptor (LACK)
Species:
Leishmania donovani
UniProt:
Q76LS6_LEIDO
TriTrypDb:
LdBPK_282970.1 , LdCL_280034500 , LdCL_280034600 , LDHU3_28.3930 , LDHU3_28.3950
Length:
312

Annotations

LeishMANIAdb interaction annotations

by homology
Contact email: avilan@ula.ve
Publication title: Leishmania mexicana: LACK (Leishmania homolog of receptors for activated C-kinase) is a plasminogen binding protein
Publication 1st author(s): Gomez-Arreaza
Publication Identifier(s): 21272581
Host organism: -1
Interaction detection method(s): enzymatic linked imunosorbent assay
Interaction type: direct interaction
Identification method participant A: identification by antibody
Identification method participant B: identification by antibody
ID(s) interactor A: Q7KFG4
ID(s) interactor B: P00747
Taxid interactor A: Leishmania mexicana
Taxid interactor B: Homo sapiens
Biological role(s) interactor A: unspecified role
Biological role(s) interactor B: unspecified role
Experimental role(s) interactor A: bait

Annotations by Jardim et al.

Intracellular protein trafficking, Guanine nucleotide-binding subunit beta-like LACK1

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 1
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 4
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 12
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0015935 small ribosomal subunit 4 12
GO:0032991 protein-containing complex 1 12
GO:0044391 ribosomal subunit 3 12
GO:1990904 ribonucleoprotein complex 2 12
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0005829 cytosol 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

Q76LS6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006793 phosphorus metabolic process 3 8
GO:0006796 phosphate-containing compound metabolic process 4 8
GO:0008152 metabolic process 1 8
GO:0009987 cellular process 1 8
GO:0016310 phosphorylation 5 8
GO:0044237 cellular metabolic process 2 8
GO:0001932 regulation of protein phosphorylation 7 1
GO:0001934 positive regulation of protein phosphorylation 8 1
GO:0006414 translational elongation 5 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0009893 positive regulation of metabolic process 4 1
GO:0010562 positive regulation of phosphorus metabolic process 6 1
GO:0010604 positive regulation of macromolecule metabolic process 5 1
GO:0019220 regulation of phosphate metabolic process 6 1
GO:0019222 regulation of metabolic process 3 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031325 positive regulation of cellular metabolic process 5 1
GO:0031399 regulation of protein modification process 6 1
GO:0031401 positive regulation of protein modification process 7 1
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 1
GO:0042325 regulation of phosphorylation 7 1
GO:0042327 positive regulation of phosphorylation 8 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0045937 positive regulation of phosphate metabolic process 7 1
GO:0048518 positive regulation of biological process 3 1
GO:0048522 positive regulation of cellular process 4 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051173 positive regulation of nitrogen compound metabolic process 5 1
GO:0051174 regulation of phosphorus metabolic process 5 1
GO:0051246 regulation of protein metabolic process 5 1
GO:0051247 positive regulation of protein metabolic process 6 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071704 organic substance metabolic process 2 1
GO:0072344 rescue of stalled ribosome 6 1
GO:0080090 regulation of primary metabolic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 8
GO:0005488 binding 1 12
GO:0016301 kinase activity 4 8
GO:0016740 transferase activity 2 8
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 8
GO:0043021 ribonucleoprotein complex binding 3 12
GO:0043022 ribosome binding 4 12
GO:0044877 protein-containing complex binding 2 12
GO:0005080 protein kinase C binding 6 1
GO:0005515 protein binding 2 1
GO:0019899 enzyme binding 3 1
GO:0019900 kinase binding 4 1
GO:0019901 protein kinase binding 5 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 307 311 PF00656 0.564
CLV_C14_Caspase3-7 32 36 PF00656 0.555
CLV_NRD_NRD_1 100 102 PF00675 0.428
CLV_PCSK_SKI1_1 101 105 PF00082 0.351
CLV_PCSK_SKI1_1 108 112 PF00082 0.308
CLV_PCSK_SKI1_1 188 192 PF00082 0.382
DEG_Kelch_Keap1_1 222 227 PF01344 0.527
DEG_Nend_UBRbox_3 1 3 PF02207 0.646
DEG_SPOP_SBC_1 29 33 PF00917 0.555
DOC_CYCLIN_yCln2_LP_2 162 168 PF00134 0.530
DOC_MAPK_gen_1 105 115 PF00069 0.628
DOC_MAPK_MEF2A_6 108 115 PF00069 0.541
DOC_USP7_MATH_1 204 208 PF00917 0.530
DOC_USP7_MATH_1 277 281 PF00917 0.515
DOC_USP7_MATH_2 279 285 PF00917 0.610
DOC_WW_Pin1_4 113 118 PF00397 0.530
DOC_WW_Pin1_4 156 161 PF00397 0.530
DOC_WW_Pin1_4 200 205 PF00397 0.530
DOC_WW_Pin1_4 233 238 PF00397 0.469
DOC_WW_Pin1_4 241 246 PF00397 0.388
DOC_WW_Pin1_4 270 275 PF00397 0.543
LIG_14-3-3_CanoR_1 11 20 PF00244 0.541
LIG_14-3-3_CanoR_1 120 130 PF00244 0.628
LIG_14-3-3_CanoR_1 256 261 PF00244 0.464
LIG_14-3-3_CanoR_1 47 51 PF00244 0.510
LIG_BRCT_BRCA1_1 154 158 PF00533 0.628
LIG_deltaCOP1_diTrp_1 150 158 PF00928 0.533
LIG_FHA_1 105 111 PF00498 0.530
LIG_FHA_1 173 179 PF00498 0.588
LIG_FHA_1 197 203 PF00498 0.552
LIG_FHA_1 63 69 PF00498 0.600
LIG_FHA_2 30 36 PF00498 0.541
LIG_LIR_Apic_2 51 57 PF02991 0.539
LIG_LIR_Gen_1 25 30 PF02991 0.597
LIG_LIR_Nem_3 25 29 PF02991 0.597
LIG_RPA_C_Fungi 6 18 PF08784 0.372
LIG_SH2_CRK 54 58 PF00017 0.630
LIG_SH2_PTP2 26 29 PF00017 0.509
LIG_SH2_STAP1 79 83 PF00017 0.509
LIG_SH2_STAT5 196 199 PF00017 0.382
LIG_SH2_STAT5 26 29 PF00017 0.440
LIG_SH3_3 231 237 PF00018 0.568
LIG_SUMO_SIM_par_1 163 169 PF11976 0.372
LIG_SUMO_SIM_par_1 198 203 PF11976 0.509
MOD_CDC14_SPxK_1 244 247 PF00782 0.419
MOD_CDK_SPxK_1 241 247 PF00069 0.414
MOD_CDK_SPxxK_3 113 120 PF00069 0.372
MOD_CK1_1 198 204 PF00069 0.509
MOD_CK1_1 49 55 PF00069 0.628
MOD_CK1_1 69 75 PF00069 0.514
MOD_CK2_1 221 227 PF00069 0.436
MOD_CK2_1 306 312 PF00069 0.465
MOD_GlcNHglycan 123 126 PF01048 0.388
MOD_GlcNHglycan 168 171 PF01048 0.372
MOD_GlcNHglycan 210 213 PF01048 0.465
MOD_GlcNHglycan 287 290 PF01048 0.384
MOD_GlcNHglycan 295 298 PF01048 0.372
MOD_GSK3_1 152 159 PF00069 0.391
MOD_GSK3_1 168 175 PF00069 0.432
MOD_GSK3_1 191 198 PF00069 0.372
MOD_GSK3_1 200 207 PF00069 0.372
MOD_GSK3_1 277 284 PF00069 0.482
MOD_GSK3_1 30 37 PF00069 0.402
MOD_GSK3_1 62 69 PF00069 0.399
MOD_GSK3_1 81 88 PF00069 0.372
MOD_NEK2_1 121 126 PF00069 0.447
MOD_NEK2_1 208 213 PF00069 0.465
MOD_NEK2_2 172 177 PF00069 0.509
MOD_NEK2_2 186 191 PF00069 0.465
MOD_NEK2_2 85 90 PF00069 0.372
MOD_PK_1 256 262 PF00069 0.546
MOD_PK_1 304 310 PF00069 0.407
MOD_PKA_2 46 52 PF00069 0.513
MOD_Plk_1 172 178 PF00069 0.509
MOD_Plk_1 186 192 PF00069 0.509
MOD_Plk_1 254 260 PF00069 0.530
MOD_Plk_1 85 91 PF00069 0.372
MOD_Plk_2-3 46 52 PF00069 0.549
MOD_Plk_4 22 28 PF00069 0.391
MOD_Plk_4 256 262 PF00069 0.517
MOD_Plk_4 290 296 PF00069 0.373
MOD_ProDKin_1 113 119 PF00069 0.372
MOD_ProDKin_1 156 162 PF00069 0.372
MOD_ProDKin_1 200 206 PF00069 0.372
MOD_ProDKin_1 233 239 PF00069 0.466
MOD_ProDKin_1 241 247 PF00069 0.388
MOD_ProDKin_1 270 276 PF00069 0.539
MOD_SUMO_rev_2 259 268 PF00179 0.446
TRG_DiLeu_BaLyEn_6 117 122 PF01217 0.509
TRG_ENDOCYTIC_2 26 29 PF00928 0.465

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I307 Leptomonas seymouri 28% 72%
A0A0N1I6C2 Leptomonas seymouri 28% 74%
A0A0N1PB16 Leptomonas seymouri 92% 100%
A0A0S4IWU9 Bodo saltans 60% 99%
A0A0S4JE21 Bodo saltans 30% 76%
A0A0S4JFE0 Bodo saltans 22% 70%
A0A0S4JMG6 Bodo saltans 22% 80%
A0A1X0NQ54 Trypanosomatidae 23% 77%
A0A1X0NQ96 Trypanosomatidae 27% 74%
A0A1X0NQI7 Trypanosomatidae 66% 98%
A0A1X0P0F0 Trypanosomatidae 28% 67%
A0A1X0P2X5 Trypanosomatidae 24% 70%
A0A1X0P551 Trypanosomatidae 22% 70%
A0A3Q8IBR2 Leishmania donovani 25% 74%
A0A3R7KUH0 Trypanosoma rangeli 27% 74%
A0A3R7M2T7 Trypanosoma rangeli 63% 98%
A0A3R7M365 Trypanosoma rangeli 27% 74%
A0A3R7MCP0 Trypanosoma rangeli 25% 68%
A0A3S5ISA7 Trypanosoma rangeli 25% 71%
A0A3S7WR72 Leishmania donovani 28% 74%
A0A3S7WVV8 Leishmania donovani 23% 76%
A0A3S7X9Q7 Leishmania donovani 22% 70%
A0CH87 Paramecium tetraurelia 28% 77%
A0DB19 Paramecium tetraurelia 29% 77%
A1CF18 Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) 28% 72%
A1L271 Danio rerio 24% 88%
A2QP30 Aspergillus niger (strain CBS 513.88 / FGSC A1513) 31% 70%
A4H666 Leishmania braziliensis 28% 100%
A4HBH0 Leishmania braziliensis 24% 76%
A4HGX7 Leishmania braziliensis 97% 100%
A4HN59 Leishmania braziliensis 22% 70%
A4HUJ0 Leishmania infantum 28% 100%
A4HYJ4 Leishmania infantum 23% 76%
A4HZL2 Leishmania infantum 25% 74%
A4IBS6 Leishmania infantum 22% 100%
A4R3M4 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) 27% 68%
A7EKM8 Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) 30% 68%
A7RWD2 Nematostella vectensis 26% 95%
A7S338 Nematostella vectensis 24% 76%
A8NEG8 Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) 27% 72%
A8X8C6 Caenorhabditis briggsae 31% 85%
A8XZJ9 Caenorhabditis briggsae 29% 80%
A9V790 Monosiga brevicollis 27% 76%
B0LSW3 Felis catus 27% 76%
B0XM00 Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) 31% 67%
B2AEZ5 Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) 28% 67%
B2B766 Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) 29% 67%
B2VWG7 Pyrenophora tritici-repentis (strain Pt-1C-BFP) 29% 68%
B3MEY6 Drosophila ananassae 27% 76%
B3NPW0 Drosophila erecta 27% 76%
B3S4I5 Trichoplax adhaerens 30% 76%
B4GAJ1 Drosophila persimilis 27% 76%
B4HRQ6 Drosophila sechellia 26% 93%
B4HSL3 Drosophila sechellia 27% 76%
B4JWA1 Drosophila grimshawi 27% 76%
B4KT48 Drosophila mojavensis 27% 76%
B4LQ21 Drosophila virilis 27% 76%
B4MY65 Drosophila willistoni 27% 76%
B4MY77 Drosophila willistoni 26% 93%
B4P6P9 Drosophila yakuba 27% 76%
B4P7Q3 Drosophila yakuba 25% 93%
B4QFZ8 Drosophila simulans 26% 93%
B4QHG6 Drosophila simulans 27% 76%
B5X3C4 Salmo salar 26% 76%
B5X3Z6 Salmo salar 27% 76%
B6GZD3 Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) 26% 67%
B6QC06 Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) 30% 69%
B6QC56 Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) 26% 68%
B7FNU7 Phaeodactylum tricornutum (strain CCAP 1055/1) 26% 71%
B7PS00 Ixodes scapularis 26% 76%
B8M0Q1 Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) 26% 68%
B8N9H4 Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) 29% 69%
B8P4B0 Postia placenta (strain ATCC 44394 / Madison 698-R) 27% 71%
B8PD53 Postia placenta (strain ATCC 44394 / Madison 698-R) 27% 73%
C0NRC6 Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432) 27% 68%
C3XVT5 Branchiostoma floridae 32% 77%
C4JPW9 Uncinocarpus reesii (strain UAMH 1704) 27% 68%
C4JZS6 Uncinocarpus reesii (strain UAMH 1704) 31% 70%
C4Q0P6 Schistosoma mansoni 29% 75%
C5FWH1 Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) 30% 68%
C5PFX0 Coccidioides posadasii (strain C735) 27% 66%
C6HTE8 Ajellomyces capsulatus (strain H143) 27% 68%
C7Z6H2 Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4) 27% 70%
C9ZL39 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 86%
C9ZQJ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 71%
C9ZVL4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 74%
C9ZZZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 83%
D0A4F2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 70%
D0A8Z9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 62% 98%
D1ZEB4 Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) 28% 68%
D3BUN1 Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500) 26% 75%
D3TLL6 Glossina morsitans morsitans 26% 76%
D4AZ50 Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) 28% 68%
D4DG66 Trichophyton verrucosum (strain HKI 0517) 28% 68%
D5GBI7 Tuber melanosporum (strain Mel28) 31% 69%
E8NHN2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 100% 100%
E9AFL2 Leishmania major 22% 100%
E9AN88 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AUX2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 73%
E9B6R6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 22% 100%
F6ZT52 Xenopus tropicalis 27% 66%
G4MQX3 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) 45% 99%
O18640 Drosophila melanogaster 48% 98%
O24076 Medicago sativa 47% 96%
O24456 Arabidopsis thaliana 47% 95%
O35353 Rattus norvegicus 26% 92%
O42248 Danio rerio 48% 98%
O42249 Oreochromis niloticus 47% 98%
O43017 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 33% 82%
O45040 Homarus americanus 27% 92%
O54927 Mus musculus 30% 74%
O54929 Mus musculus 25% 77%
P0CS32 Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) 25% 91%
P0CS33 Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) 25% 91%
P0CS42 Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) 28% 72%
P0CS43 Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) 28% 72%
P11017 Bos taurus 27% 92%
P16520 Homo sapiens 27% 92%
P17343 Caenorhabditis elegans 27% 92%
P20053 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 25% 67%
P23232 Loligo forbesii 23% 91%
P25387 Chlamydomonas reinhardtii 46% 98%
P26308 Drosophila melanogaster 27% 92%
P29387 Mus musculus 26% 92%
P29829 Drosophila melanogaster 25% 90%
P36408 Dictyostelium discoideum 24% 90%
P38011 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 38% 98%
P41318 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 25% 100%
P42841 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 23% 67%
P43033 Bos taurus 27% 76%
P43034 Homo sapiens 27% 76%
P46800 Dictyostelium discoideum 45% 95%
P49026 Nicotiana tabacum 47% 96%
P49027 Oryza sativa subsp. japonica 46% 93%
P49177 Arabidopsis thaliana 25% 83%
P49178 Zea mays 27% 82%
P52287 Rattus norvegicus 23% 92%
P54311 Rattus norvegicus 27% 92%
P54313 Rattus norvegicus 27% 92%
P61964 Homo sapiens 32% 93%
P61965 Mus musculus 32% 93%
P62871 Bos taurus 27% 92%
P62872 Canis lupus familiaris 27% 92%
P62873 Homo sapiens 27% 92%
P62874 Mus musculus 27% 92%
P62879 Homo sapiens 27% 92%
P62880 Mus musculus 27% 92%
P62883 Leishmania chagasi 100% 100%
P62884 Leishmania infantum 100% 100%
P63004 Rattus norvegicus 27% 76%
P63005 Mus musculus 27% 76%
P63243 Bos taurus 48% 98%
P63244 Homo sapiens 48% 98%
P63245 Rattus norvegicus 48% 98%
P63246 Sus scrofa 48% 98%
P63247 Gallus gallus 48% 98%
P68040 Mus musculus 48% 98%
P69103 Trypanosoma brucei brucei 62% 98%
P69104 Trypanosoma brucei rhodesiense 62% 98%
P74598 Synechocystis sp. (strain PCC 6803 / Kazusa) 31% 90%
P79147 Canis lupus familiaris 26% 92%
P79959 Xenopus laevis 25% 92%
P83774 Candida albicans (strain SC5314 / ATCC MYA-2876) 43% 98%
P93340 Nicotiana plumbaginifolia 48% 96%
P93398 Nicotiana tabacum 25% 83%
P93563 Solanum tuberosum 26% 83%
Q00664 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 26% 70%
Q01369 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 44% 99%
Q08706 Lymnaea stagnalis 23% 91%
Q0D0X6 Aspergillus terreus (strain NIH 2624 / FGSC A1156) 30% 70%
Q0P593 Bos taurus 26% 75%
Q0V8J1 Bos taurus 25% 77%
Q10281 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 46% 99%
Q10282 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 23% 100%
Q12417 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 69%
Q17963 Caenorhabditis elegans 32% 83%
Q17N69 Aedes aegypti 33% 76%
Q1LV15 Danio rerio 32% 75%
Q21215 Caenorhabditis elegans 46% 96%
Q25189 Hydra vulgaris 47% 98%
Q25306 Leishmania major 99% 100%
Q26544 Schistosoma mansoni 24% 100%
Q28I85 Xenopus tropicalis 27% 71%
Q291L9 Drosophila pseudoobscura pseudoobscura 27% 76%
Q29RH4 Bos taurus 28% 89%
Q2GT28 Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) 29% 69%
Q2HBX6 Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) 27% 69%
Q2HJH6 Bos taurus 32% 87%
Q2KIG2 Bos taurus 32% 93%
Q2TBP4 Bos taurus 26% 77%
Q2UGU1 Aspergillus oryzae (strain ATCC 42149 / RIB 40) 29% 69%
Q39336 Brassica napus 47% 95%
Q39836 Glycine max 46% 96%
Q3Y8L7 Chlamydomonas reinhardtii 28% 70%
Q40507 Nicotiana tabacum 26% 83%
Q498M4 Rattus norvegicus 32% 93%
Q4ICM0 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) 29% 68%
Q4P9P9 Ustilago maydis (strain 521 / FGSC 9021) 28% 69%
Q4Q7Y7 Leishmania major 100% 100%
Q4QCL0 Leishmania major 25% 74%
Q4QD42 Leishmania major 23% 76%
Q4QHD6 Leishmania major 28% 100%
Q4R7Y4 Macaca fascicularis 48% 98%
Q4R8E7 Macaca fascicularis 26% 75%
Q4RJN5 Tetraodon nigroviridis 26% 76%
Q4V7Z1 Xenopus laevis 29% 67%
Q4V8C4 Rattus norvegicus 31% 95%
Q4WLM7 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) 31% 67%
Q4WT34 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) 25% 69%
Q54D08 Dictyostelium discoideum 23% 100%
Q54KL5 Dictyostelium discoideum 29% 93%
Q55AR8 Dictyostelium discoideum 26% 88%
Q5A7Q3 Candida albicans (strain SC5314 / ATCC MYA-2876) 25% 80%
Q5BE22 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) 25% 69%
Q5BK30 Rattus norvegicus 26% 75%
Q5BLX8 Rattus norvegicus 28% 99%
Q5DFU0 Schistosoma japonicum 33% 89%
Q5FWQ6 Xenopus laevis 26% 75%
Q5GIS3 Pinctada fucata 23% 91%
Q5IS43 Pan troglodytes 27% 76%
Q5JTN6 Homo sapiens 32% 99%
Q5M786 Xenopus tropicalis 31% 93%
Q5R5W8 Pongo abelii 27% 92%
Q5RD06 Pongo abelii 27% 69%
Q5RE95 Pongo abelii 32% 95%
Q5REG7 Pongo abelii 26% 76%
Q5RF51 Pongo abelii 32% 87%
Q5XGI5 Xenopus tropicalis 26% 99%
Q61011 Mus musculus 23% 92%
Q61ZF6 Caenorhabditis briggsae 27% 92%
Q68FJ6 Xenopus laevis 22% 86%
Q6BSL7 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 22% 89%
Q6BU94 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 25% 75%
Q6C709 Yarrowia lipolytica (strain CLIB 122 / E 150) 25% 71%
Q6CG48 Yarrowia lipolytica (strain CLIB 122 / E 150) 27% 71%
Q6CKE8 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 23% 72%
Q6CP71 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 26% 69%
Q6FJS0 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 27% 69%
Q6FJZ9 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 25% 73%
Q6GMD2 Xenopus laevis 26% 100%
Q6L4F8 Oryza sativa subsp. japonica 46% 93%
Q6NZH4 Xenopus tropicalis 26% 76%
Q6P1V3 Xenopus tropicalis 29% 74%
Q6P2Y2 Xenopus tropicalis 26% 75%
Q6P5M2 Danio rerio 25% 100%
Q6PBD6 Xenopus tropicalis 27% 100%
Q6PBY0 Danio rerio 24% 79%
Q6PE01 Mus musculus 32% 87%
Q6PH57 Danio rerio 27% 92%
Q6PNB6 Oryctolagus cuniculus 25% 88%
Q6TMK6 Cricetulus griseus 27% 92%
Q6ZMY6 Homo sapiens 22% 66%
Q75AV4 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 25% 69%
Q75BY3 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 27% 73%
Q7K1Y4 Drosophila melanogaster 26% 93%
Q7KNS3 Drosophila melanogaster 27% 76%
Q7RY30 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 28% 69%
Q7T0P4 Xenopus laevis 27% 71%
Q7T2F6 Danio rerio 30% 74%
Q7T394 Danio rerio 26% 76%
Q7ZVF0 Danio rerio 27% 75%
Q803D2 Danio rerio 27% 76%
Q86TI4 Homo sapiens 26% 83%
Q86VZ2 Homo sapiens 32% 95%
Q8HXX0 Macaca fascicularis 27% 76%
Q8I0F4 Dictyostelium discoideum 26% 74%
Q8JZX3 Mus musculus 25% 77%
Q8N136 Homo sapiens 26% 75%
Q8NBT0 Homo sapiens 25% 77%
Q8SRB0 Encephalitozoon cuniculi (strain GB-M1) 26% 93%
Q8VE80 Mus musculus 28% 89%
Q90ZL4 Xenopus laevis 26% 76%
Q93134 Biomphalaria glabrata 48% 99%
Q93847 Caenorhabditis elegans 26% 79%
Q96DI7 Homo sapiens 32% 87%
Q96J01 Homo sapiens 28% 89%
Q9AYE4 Oryza sativa subsp. japonica 24% 99%
Q9BRX9 Homo sapiens 30% 99%
Q9C1X0 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 22% 100%
Q9C4Z6 Arabidopsis thaliana 47% 96%
Q9D7H2 Mus musculus 31% 95%
Q9D994 Mus musculus 30% 100%
Q9DAJ4 Mus musculus 28% 99%
Q9FKT5 Arabidopsis thaliana 26% 99%
Q9GL51 Sus scrofa 27% 76%
Q9HAV0 Homo sapiens 26% 92%
Q9LV28 Arabidopsis thaliana 47% 96%
Q9M2Z2 Arabidopsis thaliana 30% 98%
Q9NDC9 Caenorhabditis elegans 26% 77%
Q9NYS7 Homo sapiens 25% 77%
Q9PTR5 Gallus gallus 27% 76%
Q9SY00 Arabidopsis thaliana 33% 94%
Q9UTC7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 26% 68%
Q9V3J8 Drosophila melanogaster 31% 86%
Q9VU65 Drosophila melanogaster 26% 80%
Q9W5Z5 Takifugu rubripes 27% 73%
Q9Y6I7 Homo sapiens 30% 74%
V5B4Z8 Trypanosoma cruzi 27% 70%
V5B6G4 Trypanosoma cruzi 27% 84%
V5BDQ2 Trypanosoma cruzi 62% 98%
V5BJG9 Trypanosoma cruzi 26% 70%
V5BP59 Trypanosoma cruzi 27% 74%
V5D8N6 Trypanosoma cruzi 28% 97%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS