Putative ADP-ribosylation factor

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor, putative

Species:

Leishmania major

UniProt:

Q6IMM3_LEIMA

TriTrypDb:

LmjF.31.2280 , LMJLV39_310032100 , LMJSD75_310032100

Length:

182

Annotations

Annotations by Jardim et al.

Intracellular protein trafficking, ADP-ribosylation factor

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 12
Forrest at al. (procyclic)	yes	yes: 12
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 27

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 30

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 19
NetGPI	no	yes: 0, no: 19

Cellular components
Term	Name	Level	Count
GO:0005794	Golgi apparatus	5	14
GO:0043226	organelle	2	14
GO:0043227	membrane-bounded organelle	3	14
GO:0043229	intracellular organelle	3	14
GO:0043231	intracellular membrane-bounded organelle	4	14
GO:0110165	cellular anatomical entity	1	14

Expansion

Sequence features

Q6IMM3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q6IMM3

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	16
GO:0006886	intracellular protein transport	4	3
GO:0008104	protein localization	4	16
GO:0009987	cellular process	1	16
GO:0015031	protein transport	4	16
GO:0016192	vesicle-mediated transport	4	16
GO:0033036	macromolecule localization	2	16
GO:0045184	establishment of protein localization	3	16
GO:0046907	intracellular transport	3	3
GO:0051179	localization	1	16
GO:0051234	establishment of localization	2	16
GO:0051641	cellular localization	2	16
GO:0051649	establishment of localization in cell	3	3
GO:0070727	cellular macromolecule localization	3	16
GO:0071702	organic substance transport	4	16
GO:0071705	nitrogen compound transport	4	16

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	20
GO:0003824	catalytic activity	1	20
GO:0003924	GTPase activity	7	20
GO:0005488	binding	1	20
GO:0005525	GTP binding	5	20
GO:0016462	pyrophosphatase activity	5	20
GO:0016787	hydrolase activity	2	20
GO:0016817	hydrolase activity, acting on acid anhydrides	3	20
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	20
GO:0017076	purine nucleotide binding	4	20
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	20
GO:0019001	guanyl nucleotide binding	5	20
GO:0032553	ribonucleotide binding	3	20
GO:0032555	purine ribonucleotide binding	4	20
GO:0032561	guanyl ribonucleotide binding	5	20
GO:0035639	purine ribonucleoside triphosphate binding	4	20
GO:0036094	small molecule binding	2	20
GO:0043167	ion binding	2	20
GO:0043168	anion binding	3	20
GO:0097159	organic cyclic compound binding	2	20
GO:0097367	carbohydrate derivative binding	2	20
GO:1901265	nucleoside phosphate binding	3	20
GO:1901363	heterocyclic compound binding	2	20

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	151	153	PF00675	0.518
CLV_PCSK_FUR_1	149	153	PF00082	0.518
CLV_PCSK_KEX2_1	151	153	PF00082	0.515
CLV_PCSK_SKI1_1	59	63	PF00082	0.408
CLV_PCSK_SKI1_1	99	103	PF00082	0.460
DEG_SPOP_SBC_1	133	137	PF00917	0.418
DEG_SPOP_SBC_1	42	46	PF00917	0.518
DOC_MAPK_gen_1	15	25	PF00069	0.546
DOC_MAPK_MEF2A_6	117	124	PF00069	0.359
DOC_MAPK_MEF2A_6	15	22	PF00069	0.418
DOC_PP1_RVXF_1	57	64	PF00149	0.408
DOC_USP7_MATH_1	8	12	PF00917	0.373
DOC_WW_Pin1_4	43	48	PF00397	0.518
LIG_Actin_WH2_2	103	119	PF00022	0.408
LIG_Actin_WH2_2	46	64	PF00022	0.408
LIG_BIR_III_4	26	30	PF00653	0.418
LIG_FHA_1	134	140	PF00498	0.383
LIG_FHA_1	29	35	PF00498	0.414
LIG_FHA_1	44	50	PF00498	0.388
LIG_FHA_2	62	68	PF00498	0.408
LIG_LIR_Gen_1	7	13	PF02991	0.518
LIG_LIR_Nem_3	55	61	PF02991	0.408
LIG_LIR_Nem_3	7	12	PF02991	0.370
LIG_LIR_Nem_3	76	81	PF02991	0.518
LIG_PCNA_PIPBox_1	71	80	PF02747	0.518
LIG_Pex14_1	78	82	PF04695	0.408
LIG_PTB_Apo_2	57	64	PF02174	0.408
LIG_SH2_CRK	58	62	PF00017	0.408
LIG_SH2_STAT3	80	83	PF00017	0.518
LIG_SH2_STAT5	154	157	PF00017	0.430
LIG_TRAF2_1	103	106	PF00917	0.359
LIG_TRAF2_1	112	115	PF00917	0.283
LIG_TYR_ITIM	56	61	PF00017	0.408
LIG_UBA3_1	33	38	PF00899	0.424
MOD_CK1_1	7	13	PF00069	0.565
MOD_Cter_Amidation	13	16	PF01082	0.546
MOD_GlcNHglycan	177	180	PF01048	0.558
MOD_GlcNHglycan	6	9	PF01048	0.368
MOD_GSK3_1	133	140	PF00069	0.418
MOD_GSK3_1	171	178	PF00069	0.518
MOD_GSK3_1	4	11	PF00069	0.370
MOD_GSK3_1	41	48	PF00069	0.408
MOD_N-GLC_1	175	180	PF02516	0.616
MOD_NEK2_1	134	139	PF00069	0.504
MOD_NEK2_1	61	66	PF00069	0.408
MOD_NMyristoyl	1	7	PF02799	0.624
MOD_PIKK_1	134	140	PF00454	0.518
MOD_Plk_4	29	35	PF00069	0.418
MOD_Plk_4	8	14	PF00069	0.418
MOD_ProDKin_1	43	49	PF00069	0.518
MOD_SUMO_for_1	103	106	PF00179	0.466
MOD_SUMO_rev_2	54	61	PF00179	0.408
TRG_DiLeu_BaEn_3	105	111	PF01217	0.518
TRG_ENDOCYTIC_2	167	170	PF00928	0.418
TRG_ENDOCYTIC_2	58	61	PF00928	0.408
TRG_ER_diArg_1	148	151	PF00400	0.418
TRG_Pf-PMV_PEXEL_1	109	113	PF00026	0.408

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	52%	96%
A0A0N0P4P7	Leptomonas seymouri	35%	100%
A0A0N0P633	Leptomonas seymouri	96%	99%
A0A0N0P8D4	Leptomonas seymouri	42%	100%
A0A0N0P8G7	Leptomonas seymouri	23%	84%
A0A0N0P8Z3	Leptomonas seymouri	40%	100%
A0A0N1HS40	Leptomonas seymouri	41%	100%
A0A0N1HTN6	Leptomonas seymouri	51%	96%
A0A0N1I3A9	Leptomonas seymouri	43%	100%
A0A0N1I556	Leptomonas seymouri	78%	100%
A0A0N1I6N0	Leptomonas seymouri	43%	100%
A0A0N1I9K4	Leptomonas seymouri	28%	77%
A0A0N1IKF2	Leptomonas seymouri	33%	93%
A0A0N1PD39	Leptomonas seymouri	34%	100%
A0A0S4IQT8	Bodo saltans	39%	97%
A0A0S4IS60	Bodo saltans	50%	100%
A0A0S4J1G8	Bodo saltans	24%	83%
A0A0S4J2X3	Bodo saltans	48%	100%
A0A0S4J3L7	Bodo saltans	36%	100%
A0A0S4J5U8	Bodo saltans	33%	96%
A0A0S4J8H6	Bodo saltans	58%	100%
A0A0S4JF89	Bodo saltans	28%	82%
A0A0S4JK65	Bodo saltans	41%	100%
A0A0S4JQ13	Bodo saltans	38%	93%
A0A0S4KJ70	Bodo saltans	76%	85%
A0A0S4KKS9	Bodo saltans	57%	100%
A0A0S4KLN8	Bodo saltans	24%	76%
A0A1X0NKM5	Trypanosomatidae	41%	98%
A0A1X0NKZ8	Trypanosomatidae	37%	94%
A0A1X0NLB1	Trypanosomatidae	56%	96%
A0A1X0NLP5	Trypanosomatidae	42%	99%
A0A1X0NT19	Trypanosomatidae	46%	96%
A0A1X0NVM5	Trypanosomatidae	24%	84%
A0A1X0NYR7	Trypanosomatidae	23%	84%
A0A1X0NZX3	Trypanosomatidae	44%	100%
A0A1X0P0A2	Trypanosomatidae	35%	100%
A0A1X0P0D4	Trypanosomatidae	34%	94%
A0A1X0P1V3	Trypanosomatidae	26%	78%
A0A1X0P1Y5	Trypanosomatidae	34%	99%
A0A1X0P2L5	Trypanosomatidae	32%	94%
A0A1X0P5P0	Trypanosomatidae	79%	100%
A0A1X0P676	Trypanosomatidae	29%	95%
A0A221LG87	Leishmania donovani	32%	93%
A0A3Q8IDS2	Leishmania donovani	36%	100%
A0A3Q8IFX9	Leishmania donovani	39%	100%
A0A3Q8IK84	Leishmania donovani	28%	84%
A0A3R7KSW8	Trypanosoma rangeli	35%	100%
A0A3R7L2X6	Trypanosoma rangeli	76%	100%
A0A3R7MW79	Trypanosoma rangeli	56%	96%
A0A3R7N6U0	Trypanosoma rangeli	25%	66%
A0A3R7N9H9	Trypanosoma rangeli	25%	88%
A0A3R7NC73	Trypanosoma rangeli	46%	96%
A0A3R7NMH3	Trypanosoma rangeli	30%	96%
A0A3R7RGT1	Trypanosoma rangeli	40%	99%
A0A3S5H598	Leishmania donovani	40%	99%
A0A3S5H5A9	Leishmania donovani	52%	96%
A0A3S5IQP0	Trypanosoma rangeli	42%	98%
A0A3S5ISB1	Trypanosoma rangeli	33%	99%
A0A3S7WU76	Leishmania donovani	49%	97%
A0A3S7WV84	Leishmania donovani	28%	77%
A0A3S7X4X3	Leishmania donovani	76%	100%
A0A3S7X8N3	Leishmania donovani	41%	98%
A0A3S7XC57	Leishmania donovani	40%	100%
A0A422MUR1	Trypanosoma rangeli	28%	82%
A0A422MYB1	Trypanosoma rangeli	77%	100%
A0A422MYF8	Trypanosoma rangeli	79%	100%
A0A422MZM4	Trypanosoma rangeli	38%	94%
A0A422NNC6	Trypanosoma rangeli	41%	95%
A0A422NRN0	Trypanosoma rangeli	43%	100%
A0A422NW53	Trypanosoma rangeli	36%	98%
A0A422P3H9	Trypanosoma rangeli	32%	79%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	35%	96%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	35%	96%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	34%	96%
A4H3V3	Leishmania braziliensis	38%	99%
A4H3W8	Leishmania braziliensis	50%	96%
A4H449	Leishmania braziliensis	32%	93%
A4H8R6	Leishmania braziliensis	37%	100%
A4H8V3	Leishmania braziliensis	47%	97%
A4H9M3	Leishmania braziliensis	28%	77%
A4HH98	Leishmania braziliensis	44%	100%
A4HIB4	Leishmania braziliensis	27%	77%
A4HJL1	Leishmania braziliensis	96%	100%
A4HJR7	Leishmania braziliensis	77%	100%
A4HLP5	Leishmania braziliensis	27%	83%
A4HM52	Leishmania braziliensis	43%	98%
A4HQE3	Leishmania braziliensis	40%	100%
A4HS29	Leishmania infantum	39%	99%
A4HS43	Leishmania infantum	52%	96%
A4HSC6	Leishmania infantum	32%	93%
A4HX34	Leishmania infantum	36%	100%
A4HX72	Leishmania infantum	49%	97%
A4HXY7	Leishmania infantum	28%	77%
A4I4E4	Leishmania infantum	43%	100%
A4I5R5	Leishmania infantum	39%	100%
A4I784	Leishmania infantum	76%	100%
A4I946	Leishmania infantum	28%	84%
A4IAR4	Leishmania infantum	41%	98%
A4IE34	Leishmania infantum	40%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	32%	96%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	35%	96%
A6NH57	Homo sapiens	41%	100%
A8ISN6	Chlamydomonas reinhardtii	41%	100%
B5FYQ0	Taeniopygia guttata	41%	100%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	94%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	99%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	96%
C9ZVS8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	85%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	96%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	94%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	96%
C9ZYS6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	83%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	98%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	67%
E9ADU4	Leishmania major	44%	100%
E9AEJ0	Leishmania major	42%	100%
E9AHL7	Leishmania infantum	100%	100%
E9AIU0	Leishmania braziliensis	39%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	99%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	93%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	97%
E9ARQ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	77%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
E9B420	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	84%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	98%
F4IZ82	Arabidopsis thaliana	33%	100%
O00909	Dictyostelium discoideum	64%	100%
O01803	Caenorhabditis elegans	27%	86%
O04266	Brassica campestris	33%	94%
O04267	Brassica campestris	32%	93%
O04834	Arabidopsis thaliana	33%	94%
O08697	Rattus norvegicus	49%	99%
O23778	Catharanthus roseus	66%	100%
O42819	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	30%	85%
O45379	Caenorhabditis elegans	44%	99%
O48649	Salix bakko	67%	100%
O48920	Vigna unguiculata	67%	100%
O88848	Mus musculus	41%	98%
P01123	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	88%
P07560	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	85%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	35%	96%
P0C950	Aspergillus niger	34%	96%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	96%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	67%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	67%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	96%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	96%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	96%
P0CT17	Magnaporthe oryzae (strain Y34)	35%	96%
P0DH91	Arabidopsis thaliana	68%	100%
P10949	Bos taurus	25%	80%
P11023	Bos taurus	25%	83%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	64%	100%
P18085	Homo sapiens	66%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	65%	100%
P19892	Arabidopsis thaliana	29%	83%
P20336	Homo sapiens	26%	83%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	96%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	67%	100%
P25160	Drosophila melanogaster	51%	100%
P25766	Oryza sativa subsp. japonica	27%	81%
P26990	Gallus gallus	59%	100%
P26991	Giardia intestinalis	64%	95%
P29687	Nicotiana tabacum	29%	91%
P31582	Arabidopsis thaliana	25%	91%
P31583	Nicotiana plumbaginifolia	27%	91%
P33723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	25%	90%
P34142	Dictyostelium discoideum	28%	86%
P34143	Dictyostelium discoideum	26%	93%
P34212	Caenorhabditis elegans	47%	100%
P34727	Ajellomyces capsulatus	65%	99%
P35283	Mus musculus	26%	75%
P35284	Rattus norvegicus	26%	75%
P35285	Mus musculus	32%	94%
P36018	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	78%
P36397	Arabidopsis thaliana	68%	100%
P36404	Homo sapiens	48%	99%
P36405	Homo sapiens	41%	100%
P36412	Dictyostelium discoideum	30%	85%
P36536	Mus musculus	31%	92%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	67%	100%
P37996	Rattus norvegicus	42%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	99%
P38146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	91%
P40616	Homo sapiens	52%	100%
P40617	Homo sapiens	43%	91%
P40940	Arabidopsis thaliana	54%	100%
P40945	Drosophila melanogaster	65%	100%
P40946	Drosophila melanogaster	58%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	54%	99%
P49076	Zea mays	68%	100%
P49702	Gallus gallus	65%	100%
P49703	Homo sapiens	39%	91%
P51152	Canis lupus familiaris	26%	88%
P51154	Canis lupus familiaris	33%	94%
P51156	Rattus norvegicus	27%	71%
P51643	Xenopus laevis	69%	100%
P51644	Xenopus laevis	69%	100%
P51645	Xenopus laevis	58%	100%
P51646	Rattus norvegicus	50%	100%
P51821	Chlamydomonas reinhardtii	69%	100%
P51822	Daucus carota	67%	100%
P51823	Oryza sativa subsp. japonica	69%	100%
P51824	Solanum tuberosum	69%	92%
P52884	Solanum lycopersicum	34%	94%
P56559	Homo sapiens	46%	95%
P61204	Homo sapiens	68%	100%
P61205	Mus musculus	68%	100%
P61206	Rattus norvegicus	68%	100%
P61207	Takifugu rubripes	68%	100%
P61208	Mus musculus	46%	95%
P61209	Drosophila melanogaster	69%	100%
P61210	Locusta migratoria	69%	100%
P61211	Mus musculus	52%	100%
P61212	Rattus norvegicus	52%	100%
P61213	Mus musculus	44%	91%
P61214	Rattus norvegicus	44%	91%
P61750	Mus musculus	66%	100%
P61751	Rattus norvegicus	66%	100%
P62330	Homo sapiens	59%	100%
P62331	Mus musculus	59%	100%
P62332	Rattus norvegicus	59%	100%
P62823	Mus musculus	25%	80%
P62824	Rattus norvegicus	25%	80%
P63011	Mus musculus	26%	83%
P63012	Rattus norvegicus	26%	83%
P78976	Hypocrea jecorina	35%	96%
P84077	Homo sapiens	69%	100%
P84078	Mus musculus	69%	100%
P84079	Rattus norvegicus	69%	100%
P84080	Bos taurus	69%	100%
P84081	Bos taurus	69%	100%
P84082	Rattus norvegicus	69%	100%
P84083	Rattus norvegicus	65%	100%
P84084	Mus musculus	65%	100%
P84085	Homo sapiens	65%	100%
P90726	Caenorhabditis briggsae	27%	90%
P91924	Dugesia japonica	68%	99%
Q007T5	Sus scrofa	59%	100%
Q01474	Arabidopsis thaliana	33%	94%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	96%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	92%
Q06396	Oryza sativa subsp. japonica	68%	100%
Q06849	Drosophila melanogaster	43%	99%
Q06AU3	Sus scrofa	26%	83%
Q06AU4	Sus scrofa	26%	70%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	98%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	35%	96%
Q0IIM2	Bos taurus	41%	98%
Q0ILQ6	Oryza sativa subsp. japonica	28%	90%
Q0P5N6	Homo sapiens	28%	92%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	36%	98%
Q0VC18	Bos taurus	38%	91%
Q10943	Caenorhabditis elegans	68%	100%
Q13636	Homo sapiens	31%	94%
Q13795	Homo sapiens	35%	91%
Q15771	Homo sapiens	29%	90%
Q17QB7	Bos taurus	29%	90%
Q17QU4	Bos taurus	24%	85%
Q18510	Caenorhabditis elegans	42%	96%
Q19705	Caenorhabditis elegans	41%	99%
Q1MTE5	Danio rerio	41%	100%
Q1ZXA5	Dictyostelium discoideum	35%	98%
Q20758	Caenorhabditis elegans	51%	100%
Q23445	Caenorhabditis elegans	31%	94%
Q25761	Plasmodium falciparum (isolate NF54)	61%	100%
Q29RR0	Bos taurus	27%	71%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	36%	96%
Q2KI07	Bos taurus	34%	98%
Q2KJ96	Bos taurus	50%	100%
Q2TA37	Bos taurus	48%	99%
Q2TBW6	Bos taurus	42%	100%
Q2YDM1	Bos taurus	52%	100%
Q32LJ2	Bos taurus	34%	91%
Q39434	Beta vulgaris	27%	85%
Q3SXC5	Mus musculus	43%	95%
Q3SZF2	Bos taurus	68%	100%
Q3T0D7	Bos taurus	31%	92%
Q3T0M9	Bos taurus	44%	91%
Q3T0T7	Bos taurus	32%	92%
Q40191	Lotus japonicus	28%	81%
Q40193	Lotus japonicus	27%	84%
Q40195	Lotus japonicus	27%	83%
Q40520	Nicotiana tabacum	28%	82%
Q40522	Nicotiana tabacum	28%	82%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	35%	96%
Q4Q0D7	Leishmania major	39%	100%
Q4Q404	Leishmania major	26%	84%
Q4Q5Y0	Leishmania major	76%	98%
Q4Q756	Leishmania major	39%	100%
Q4QDS9	Leishmania major	28%	77%
Q4QEJ1	Leishmania major	50%	100%
Q4QEM9	Leishmania major	36%	100%
Q4QJK0	Leishmania major	33%	100%
Q4R4R9	Macaca fascicularis	26%	83%
Q4R4S4	Macaca fascicularis	34%	98%
Q4R5P2	Macaca fascicularis	69%	100%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	35%	96%
Q504M8	Mus musculus	27%	70%
Q52NJ3	Sus scrofa	31%	92%
Q52NJ4	Sus scrofa	41%	100%
Q54GY8	Dictyostelium discoideum	24%	90%
Q54HK2	Dictyostelium discoideum	47%	96%
Q54I24	Dictyostelium discoideum	46%	84%
Q54JJ3	Dictyostelium discoideum	54%	96%
Q54K69	Dictyostelium discoideum	31%	92%
Q54NU2	Dictyostelium discoideum	30%	89%
Q54R04	Dictyostelium discoideum	36%	98%
Q54RX9	Dictyostelium discoideum	35%	85%
Q54UF1	Dictyostelium discoideum	47%	99%
Q54V41	Dictyostelium discoideum	53%	97%
Q54V47	Dictyostelium discoideum	56%	97%
Q54Y14	Dictyostelium discoideum	35%	94%
Q54YV7	Dictyostelium discoideum	26%	93%
Q559R0	Dictyostelium discoideum	31%	97%
Q55AD9	Dictyostelium discoideum	47%	99%
Q55EG6	Dictyostelium discoideum	24%	82%
Q58735	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	26%	100%
Q58DI9	Bos taurus	41%	100%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	36%	96%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	96%
Q5BK71	Rattus norvegicus	42%	100%
Q5E9I6	Bos taurus	68%	100%
Q5EA19	Bos taurus	32%	90%
Q5HZY2	Rattus norvegicus	32%	92%
Q5M9P8	Danio rerio	43%	98%
Q5PYH3	Sus scrofa	32%	92%
Q5R4G5	Pongo abelii	42%	98%
Q5R548	Pongo abelii	31%	92%
Q5R579	Pongo abelii	35%	91%
Q5R5P7	Pongo abelii	68%	100%
Q5R6E7	Pongo abelii	34%	98%
Q5RCF1	Pongo abelii	66%	100%
Q5RCQ6	Pongo abelii	34%	100%
Q5REU3	Pongo abelii	39%	91%
Q5RFN0	Pongo abelii	32%	89%
Q5U1Y1	Rattus norvegicus	27%	70%
Q5VLR7	Leishmania donovani	100%	100%
Q5ZKQ8	Gallus gallus	32%	98%
Q5ZLG1	Gallus gallus	26%	88%
Q60Z38	Caenorhabditis briggsae	44%	96%
Q61LA8	Caenorhabditis briggsae	69%	100%
Q627K4	Caenorhabditis briggsae	41%	99%
Q63055	Rattus norvegicus	35%	91%
Q64008	Mus musculus	27%	70%
Q66HA6	Rattus norvegicus	34%	98%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	32%	96%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	34%	96%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	36%	96%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	34%	96%
Q6GQP4	Rattus norvegicus	30%	94%
Q6IQ22	Homo sapiens	26%	75%
Q6NZW8	Danio rerio	35%	98%
Q6P068	Mus musculus	46%	100%
Q6P3A9	Mus musculus	44%	100%
Q6P8C8	Xenopus tropicalis	30%	98%
Q6T311	Homo sapiens	35%	97%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	96%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	66%	100%
Q76NM7	Plasmodium falciparum (isolate 3D7)	30%	88%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	62%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	69%	98%
Q80ZU0	Mus musculus	49%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	96%
Q8BGR6	Mus musculus	32%	89%
Q8BHC1	Mus musculus	24%	85%
Q8BSL7	Mus musculus	69%	100%
Q8BXL7	Mus musculus	35%	91%
Q8CAM5	Mus musculus	25%	68%
Q8HZJ5	Bos taurus	22%	83%
Q8MQT8	Giardia intestinalis	31%	95%
Q8MXS1	Caenorhabditis elegans	26%	90%
Q8N4G2	Homo sapiens	43%	95%
Q8N8L6	Homo sapiens	34%	75%
Q8QHI3	Xenopus laevis	42%	100%
Q8VEA8	Mus musculus	28%	91%
Q8VEH3	Mus musculus	32%	98%
Q8VY57	Arabidopsis thaliana	33%	99%
Q8W4C8	Arabidopsis thaliana	33%	99%
Q921E2	Mus musculus	30%	94%
Q923S9	Mus musculus	29%	90%
Q93Y31	Arabidopsis thaliana	32%	99%
Q94231	Caenorhabditis elegans	53%	100%
Q94650	Plasmodium falciparum	62%	100%
Q94986	Caenorhabditis elegans	25%	83%
Q96283	Arabidopsis thaliana	29%	84%
Q96361	Brassica rapa subsp. pekinensis	55%	100%
Q969Q4	Homo sapiens	42%	93%
Q96AH8	Homo sapiens	29%	91%
Q96AX2	Homo sapiens	27%	82%
Q96BM9	Homo sapiens	32%	98%
Q96DA2	Homo sapiens	24%	85%
Q96E17	Homo sapiens	25%	80%
Q96KC2	Homo sapiens	49%	100%
Q99P58	Mus musculus	22%	83%
Q99PE9	Mus musculus	39%	91%
Q9BZG1	Homo sapiens	26%	70%
Q9CB01	Arabidopsis thaliana	29%	90%
Q9CQC9	Mus musculus	32%	92%
Q9CQW2	Mus musculus	34%	98%
Q9D0J4	Mus musculus	49%	99%
Q9D4P0	Mus musculus	49%	100%
Q9FE79	Arabidopsis thaliana	28%	82%
Q9FGK5	Arabidopsis thaliana	27%	82%
Q9FIF9	Arabidopsis thaliana	30%	84%
Q9FJN8	Arabidopsis thaliana	28%	81%
Q9H0F7	Homo sapiens	42%	98%
Q9JKM7	Mus musculus	26%	82%
Q9LH50	Arabidopsis thaliana	30%	82%
Q9LNW1	Arabidopsis thaliana	29%	85%
Q9LQC8	Arabidopsis thaliana	68%	100%
Q9N6B0	Leishmania donovani	43%	100%
Q9NR31	Homo sapiens	31%	92%
Q9NVJ2	Homo sapiens	34%	98%
Q9NXU5	Homo sapiens	32%	89%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	32%	96%
Q9QVY3	Cricetulus griseus	32%	92%
Q9QXJ4	Mus musculus	31%	75%
Q9SF92	Arabidopsis thaliana	27%	89%
Q9SHU5	Arabidopsis thaliana	58%	89%
Q9SMQ6	Arabidopsis thaliana	28%	81%
Q9SN68	Arabidopsis thaliana	26%	91%
Q9U0T6	Leishmania major	52%	96%
Q9UL26	Homo sapiens	33%	94%
Q9VHV5	Drosophila melanogaster	32%	98%
Q9WUL7	Mus musculus	41%	100%
Q9XZX2	Leishmania major	39%	99%
Q9Y689	Homo sapiens	50%	100%
Q9Y6B6	Homo sapiens	32%	92%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	57%	99%
Q9ZPX1	Arabidopsis thaliana	44%	98%
V5B891	Trypanosoma cruzi	46%	96%
V5BBM5	Trypanosoma cruzi	24%	88%
V5BU30	Trypanosoma cruzi	28%	79%
V5D027	Trypanosoma cruzi	28%	83%
V5DJR8	Trypanosoma cruzi	42%	98%