Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QJI7_LEIMA

TriTrypDb:

LmjF.05.0160 , LMJLV39_050006500 , LMJSD75_050006500

Length:

518

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJI7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJI7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.662
CLV_NRD_NRD_1	254	256	PF00675	0.541
CLV_NRD_NRD_1	420	422	PF00675	0.695
CLV_PCSK_KEX2_1	105	107	PF00082	0.662
CLV_PCSK_KEX2_1	254	256	PF00082	0.541
CLV_PCSK_KEX2_1	420	422	PF00082	0.695
CLV_PCSK_KEX2_1	429	431	PF00082	0.525
CLV_PCSK_PC1ET2_1	429	431	PF00082	0.461
CLV_PCSK_SKI1_1	17	21	PF00082	0.495
CLV_PCSK_SKI1_1	421	425	PF00082	0.625
DEG_COP1_1	238	246	PF00400	0.509
DEG_SPOP_SBC_1	217	221	PF00917	0.590
DOC_MAPK_gen_1	428	435	PF00069	0.481
DOC_MAPK_MEF2A_6	428	435	PF00069	0.474
DOC_PP1_RVXF_1	267	274	PF00149	0.437
DOC_PP2B_LxvP_1	507	510	PF13499	0.558
DOC_USP7_MATH_1	122	126	PF00917	0.552
DOC_USP7_MATH_1	224	228	PF00917	0.676
DOC_USP7_MATH_1	311	315	PF00917	0.487
DOC_USP7_MATH_1	317	321	PF00917	0.495
DOC_USP7_MATH_1	411	415	PF00917	0.505
DOC_USP7_MATH_1	461	465	PF00917	0.655
DOC_USP7_MATH_1	485	489	PF00917	0.676
DOC_WW_Pin1_4	168	173	PF00397	0.691
DOC_WW_Pin1_4	174	179	PF00397	0.591
DOC_WW_Pin1_4	213	218	PF00397	0.616
DOC_WW_Pin1_4	238	243	PF00397	0.721
DOC_WW_Pin1_4	451	456	PF00397	0.511
DOC_WW_Pin1_4	476	481	PF00397	0.689
DOC_WW_Pin1_4	494	499	PF00397	0.579
LIG_14-3-3_CanoR_1	105	112	PF00244	0.471
LIG_14-3-3_CanoR_1	379	386	PF00244	0.419
LIG_APCC_ABBAyCdc20_2	5	11	PF00400	0.605
LIG_CtBP_PxDLS_1	456	460	PF00389	0.476
LIG_eIF4E_1	186	192	PF01652	0.475
LIG_FHA_1	375	381	PF00498	0.423
LIG_FHA_2	154	160	PF00498	0.639
LIG_FHA_2	285	291	PF00498	0.570
LIG_FHA_2	296	302	PF00498	0.473
LIG_FHA_2	368	374	PF00498	0.510
LIG_FHA_2	58	64	PF00498	0.577
LIG_FHA_2	94	100	PF00498	0.483
LIG_GSK3_LRP6_1	168	173	PF00069	0.564
LIG_Integrin_RGD_1	157	159	PF01839	0.625
LIG_LIR_Gen_1	272	278	PF02991	0.410
LIG_LIR_Nem_3	200	205	PF02991	0.555
LIG_LIR_Nem_3	272	276	PF02991	0.414
LIG_MYND_1	457	461	PF01753	0.487
LIG_SH2_STAP1	393	397	PF00017	0.465
LIG_SH2_STAP1	492	496	PF00017	0.625
LIG_SH3_2	152	157	PF14604	0.658
LIG_SH3_3	149	155	PF00018	0.665
LIG_SH3_3	166	172	PF00018	0.669
LIG_SH3_3	211	217	PF00018	0.686
LIG_SH3_3	479	485	PF00018	0.661
LIG_SH3_3	495	501	PF00018	0.440
LIG_Sin3_3	302	309	PF02671	0.413
LIG_SUMO_SIM_anti_2	272	278	PF11976	0.516
LIG_TRAF2_1	231	234	PF00917	0.662
LIG_TRAF2_1	287	290	PF00917	0.542
LIG_TRAF2_1	370	373	PF00917	0.571
LIG_TRAF2_1	441	444	PF00917	0.373
LIG_WRC_WIRS_1	270	275	PF05994	0.440
MOD_CK1_1	104	110	PF00069	0.589
MOD_CK1_1	142	148	PF00069	0.766
MOD_CK1_1	216	222	PF00069	0.801
MOD_CK1_1	448	454	PF00069	0.528
MOD_CK1_1	476	482	PF00069	0.680
MOD_CK1_1	490	496	PF00069	0.599
MOD_CK2_1	104	110	PF00069	0.583
MOD_CK2_1	228	234	PF00069	0.595
MOD_CK2_1	284	290	PF00069	0.566
MOD_CK2_1	295	301	PF00069	0.472
MOD_CK2_1	367	373	PF00069	0.510
MOD_CK2_1	438	444	PF00069	0.373
MOD_CK2_1	57	63	PF00069	0.576
MOD_GlcNHglycan	120	123	PF01048	0.641
MOD_GlcNHglycan	144	147	PF01048	0.643
MOD_GlcNHglycan	180	183	PF01048	0.536
MOD_GlcNHglycan	238	241	PF01048	0.613
MOD_GlcNHglycan	307	312	PF01048	0.477
MOD_GlcNHglycan	319	322	PF01048	0.570
MOD_GlcNHglycan	408	411	PF01048	0.500
MOD_GlcNHglycan	413	416	PF01048	0.504
MOD_GlcNHglycan	463	466	PF01048	0.626
MOD_GlcNHglycan	475	478	PF01048	0.711
MOD_GlcNHglycan	489	492	PF01048	0.629
MOD_GSK3_1	118	125	PF00069	0.557
MOD_GSK3_1	170	177	PF00069	0.664
MOD_GSK3_1	213	220	PF00069	0.608
MOD_GSK3_1	224	231	PF00069	0.559
MOD_GSK3_1	265	272	PF00069	0.464
MOD_GSK3_1	307	314	PF00069	0.408
MOD_GSK3_1	328	335	PF00069	0.511
MOD_GSK3_1	363	370	PF00069	0.572
MOD_GSK3_1	374	381	PF00069	0.492
MOD_GSK3_1	451	458	PF00069	0.585
MOD_GSK3_1	472	479	PF00069	0.642
MOD_GSK3_1	486	493	PF00069	0.659
MOD_GSK3_1	499	506	PF00069	0.571
MOD_N-GLC_1	123	128	PF02516	0.700
MOD_N-GLC_1	342	347	PF02516	0.541
MOD_N-GLC_1	438	443	PF02516	0.442
MOD_NEK2_1	139	144	PF00069	0.630
MOD_NEK2_1	192	197	PF00069	0.583
MOD_NEK2_1	236	241	PF00069	0.648
MOD_NEK2_1	375	380	PF00069	0.493
MOD_NEK2_1	445	450	PF00069	0.451
MOD_NEK2_1	503	508	PF00069	0.612
MOD_NEK2_2	295	300	PF00069	0.523
MOD_PIKK_1	139	145	PF00454	0.705
MOD_PIKK_1	192	198	PF00454	0.473
MOD_PIKK_1	378	384	PF00454	0.449
MOD_PIKK_1	501	507	PF00454	0.494
MOD_PKA_2	104	110	PF00069	0.642
MOD_PKA_2	247	253	PF00069	0.561
MOD_PKA_2	311	317	PF00069	0.528
MOD_PKA_2	378	384	PF00069	0.473
MOD_Plk_1	438	444	PF00069	0.373
MOD_Plk_4	110	116	PF00069	0.586
MOD_Plk_4	503	509	PF00069	0.611
MOD_ProDKin_1	168	174	PF00069	0.692
MOD_ProDKin_1	213	219	PF00069	0.621
MOD_ProDKin_1	238	244	PF00069	0.711
MOD_ProDKin_1	451	457	PF00069	0.518
MOD_ProDKin_1	476	482	PF00069	0.687
MOD_ProDKin_1	494	500	PF00069	0.574
MOD_SUMO_rev_2	261	271	PF00179	0.406
MOD_SUMO_rev_2	54	62	PF00179	0.500
TRG_ER_diArg_1	253	255	PF00400	0.561
TRG_ER_diArg_1	419	421	PF00400	0.647
TRG_Pf-PMV_PEXEL_1	254	259	PF00026	0.420
TRG_Pf-PMV_PEXEL_1	286	290	PF00026	0.506
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.670
TRG_Pf-PMV_PEXEL_1	95	99	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKE8	Leptomonas seymouri	38%	98%
A0A3S7WNZ9	Leishmania donovani	86%	100%
A4H462	Leishmania braziliensis	65%	95%
A4HSD1	Leishmania infantum	86%	100%
E9AKC0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%