Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

basal body component, putative

Species:

Leishmania major

UniProt:

Q4QJI6_LEIMA

TriTrypDb:

LmjF.05.0170 , LMJLV39_050006600 , LMJSD75_050006600

Length:

761

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	2
GO:0036064	ciliary basal body	3	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QJI6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJI6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	715	719	PF00656	0.598
CLV_NRD_NRD_1	139	141	PF00675	0.473
CLV_NRD_NRD_1	16	18	PF00675	0.523
CLV_NRD_NRD_1	219	221	PF00675	0.640
CLV_NRD_NRD_1	298	300	PF00675	0.459
CLV_NRD_NRD_1	370	372	PF00675	0.656
CLV_NRD_NRD_1	415	417	PF00675	0.654
CLV_NRD_NRD_1	643	645	PF00675	0.649
CLV_NRD_NRD_1	673	675	PF00675	0.656
CLV_PCSK_KEX2_1	139	141	PF00082	0.542
CLV_PCSK_KEX2_1	15	17	PF00082	0.495
CLV_PCSK_KEX2_1	219	221	PF00082	0.640
CLV_PCSK_KEX2_1	298	300	PF00082	0.452
CLV_PCSK_KEX2_1	370	372	PF00082	0.656
CLV_PCSK_KEX2_1	415	417	PF00082	0.796
CLV_PCSK_KEX2_1	42	44	PF00082	0.418
CLV_PCSK_KEX2_1	643	645	PF00082	0.649
CLV_PCSK_KEX2_1	672	674	PF00082	0.658
CLV_PCSK_PC1ET2_1	42	44	PF00082	0.418
CLV_PCSK_SKI1_1	153	157	PF00082	0.431
CLV_PCSK_SKI1_1	250	254	PF00082	0.491
CLV_PCSK_SKI1_1	396	400	PF00082	0.550
CLV_PCSK_SKI1_1	424	428	PF00082	0.558
CLV_PCSK_SKI1_1	643	647	PF00082	0.692
CLV_PCSK_SKI1_1	674	678	PF00082	0.649
CLV_PCSK_SKI1_1	74	78	PF00082	0.373
CLV_PCSK_SKI1_1	746	750	PF00082	0.468
CLV_Separin_Metazoa	421	425	PF03568	0.535
DEG_APCC_DBOX_1	188	196	PF00400	0.591
DEG_APCC_DBOX_1	314	322	PF00400	0.549
DEG_APCC_DBOX_1	415	423	PF00400	0.641
DEG_SPOP_SBC_1	349	353	PF00917	0.555
DEG_SPOP_SBC_1	354	358	PF00917	0.549
DEG_SPOP_SBC_1	706	710	PF00917	0.585
DEG_SPOP_SBC_1	719	723	PF00917	0.569
DOC_CDC14_PxL_1	399	407	PF14671	0.566
DOC_CKS1_1	375	380	PF01111	0.607
DOC_CKS1_1	445	450	PF01111	0.769
DOC_CKS1_1	586	591	PF01111	0.662
DOC_CYCLIN_RxL_1	486	497	PF00134	0.657
DOC_CYCLIN_yCln2_LP_2	422	428	PF00134	0.542
DOC_MAPK_DCC_7	479	488	PF00069	0.616
DOC_MAPK_gen_1	139	145	PF00069	0.530
DOC_MAPK_gen_1	479	488	PF00069	0.666
DOC_MAPK_MEF2A_6	479	488	PF00069	0.616
DOC_PP2B_LxvP_1	400	403	PF13499	0.460
DOC_PP2B_LxvP_1	527	530	PF13499	0.649
DOC_PP2B_LxvP_1	637	640	PF13499	0.620
DOC_USP7_MATH_1	181	185	PF00917	0.667
DOC_USP7_MATH_1	188	192	PF00917	0.606
DOC_USP7_MATH_1	198	202	PF00917	0.549
DOC_USP7_MATH_1	354	358	PF00917	0.579
DOC_USP7_MATH_1	474	478	PF00917	0.631
DOC_USP7_MATH_1	517	521	PF00917	0.691
DOC_USP7_MATH_1	535	539	PF00917	0.577
DOC_USP7_MATH_1	546	550	PF00917	0.767
DOC_USP7_MATH_1	650	654	PF00917	0.786
DOC_USP7_MATH_1	658	662	PF00917	0.776
DOC_USP7_MATH_1	697	701	PF00917	0.626
DOC_USP7_MATH_1	719	723	PF00917	0.631
DOC_USP7_MATH_1	727	731	PF00917	0.644
DOC_WW_Pin1_4	213	218	PF00397	0.671
DOC_WW_Pin1_4	361	366	PF00397	0.612
DOC_WW_Pin1_4	374	379	PF00397	0.563
DOC_WW_Pin1_4	444	449	PF00397	0.669
DOC_WW_Pin1_4	458	463	PF00397	0.802
DOC_WW_Pin1_4	513	518	PF00397	0.646
DOC_WW_Pin1_4	550	555	PF00397	0.692
DOC_WW_Pin1_4	566	571	PF00397	0.645
DOC_WW_Pin1_4	582	587	PF00397	0.524
DOC_WW_Pin1_4	598	603	PF00397	0.605
DOC_WW_Pin1_4	652	657	PF00397	0.720
DOC_WW_Pin1_4	674	679	PF00397	0.738
DOC_WW_Pin1_4	699	704	PF00397	0.641
LIG_14-3-3_CanoR_1	153	162	PF00244	0.507
LIG_14-3-3_CanoR_1	182	186	PF00244	0.634
LIG_14-3-3_CanoR_1	220	230	PF00244	0.593
LIG_14-3-3_CanoR_1	292	297	PF00244	0.535
LIG_14-3-3_CanoR_1	416	426	PF00244	0.618
LIG_14-3-3_CanoR_1	501	508	PF00244	0.612
LIG_14-3-3_CanoR_1	672	679	PF00244	0.644
LIG_APCC_ABBA_1	232	237	PF00400	0.606
LIG_BIR_III_2	258	262	PF00653	0.580
LIG_BRCT_BRCA1_1	460	464	PF00533	0.671
LIG_EVH1_1	527	531	PF00568	0.614
LIG_FHA_1	144	150	PF00498	0.486
LIG_FHA_1	237	243	PF00498	0.630
LIG_FHA_1	465	471	PF00498	0.660
LIG_FHA_2	241	247	PF00498	0.607
LIG_FHA_2	687	693	PF00498	0.718
LIG_Pex14_2	395	399	PF04695	0.479
LIG_SH2_NCK_1	433	437	PF00017	0.553
LIG_SH2_NCK_1	724	728	PF00017	0.613
LIG_SH2_NCK_1	98	102	PF00017	0.387
LIG_SH2_SRC	98	101	PF00017	0.389
LIG_SH2_STAP1	89	93	PF00017	0.459
LIG_SH2_STAP1	98	102	PF00017	0.365
LIG_SH2_STAT3	38	41	PF00017	0.433
LIG_SH2_STAT3	632	635	PF00017	0.741
LIG_SH2_STAT5	121	124	PF00017	0.455
LIG_SH2_STAT5	388	391	PF00017	0.526
LIG_SH3_1	481	487	PF00018	0.590
LIG_SH3_2	484	489	PF14604	0.588
LIG_SH3_2	599	604	PF14604	0.573
LIG_SH3_3	182	188	PF00018	0.595
LIG_SH3_3	437	443	PF00018	0.679
LIG_SH3_3	459	465	PF00018	0.641
LIG_SH3_3	481	487	PF00018	0.590
LIG_SH3_3	525	531	PF00018	0.606
LIG_SH3_3	583	589	PF00018	0.606
LIG_SH3_3	596	602	PF00018	0.692
LIG_SH3_3	630	636	PF00018	0.544
LIG_SH3_CIN85_PxpxPR_1	531	536	PF14604	0.664
LIG_SUMO_SIM_par_1	579	585	PF11976	0.675
LIG_TRAF2_1	244	247	PF00917	0.642
LIG_TRAF2_1	328	331	PF00917	0.657
LIG_TRAF2_1	520	523	PF00917	0.619
LIG_TRAF2_1	577	580	PF00917	0.601
LIG_TRAF2_1	97	100	PF00917	0.497
LIG_WW_3	412	416	PF00397	0.593
MOD_CDC14_SPxK_1	216	219	PF00782	0.582
MOD_CDC14_SPxK_1	553	556	PF00782	0.664
MOD_CDC14_SPxK_1	571	574	PF00782	0.711
MOD_CDC14_SPxK_1	601	604	PF00782	0.770
MOD_CDK_SPxK_1	213	219	PF00069	0.586
MOD_CDK_SPxK_1	374	380	PF00069	0.627
MOD_CDK_SPxK_1	550	556	PF00069	0.662
MOD_CDK_SPxK_1	568	574	PF00069	0.712
MOD_CDK_SPxK_1	598	604	PF00069	0.676
MOD_CDK_SPxxK_3	213	220	PF00069	0.586
MOD_CK1_1	163	169	PF00069	0.572
MOD_CK1_1	191	197	PF00069	0.759
MOD_CK1_1	358	364	PF00069	0.654
MOD_CK1_1	562	568	PF00069	0.597
MOD_CK1_1	585	591	PF00069	0.663
MOD_CK1_1	626	632	PF00069	0.677
MOD_CK1_1	657	663	PF00069	0.626
MOD_CK1_1	680	686	PF00069	0.718
MOD_CK1_1	698	704	PF00069	0.546
MOD_CK1_1	705	711	PF00069	0.593
MOD_CK1_1	712	718	PF00069	0.549
MOD_CK1_1	720	726	PF00069	0.677
MOD_CK1_1	730	736	PF00069	0.808
MOD_CK2_1	240	246	PF00069	0.613
MOD_CK2_1	503	509	PF00069	0.648
MOD_CK2_1	516	522	PF00069	0.588
MOD_CK2_1	658	664	PF00069	0.639
MOD_CK2_1	686	692	PF00069	0.763
MOD_Cter_Amidation	641	644	PF01082	0.652
MOD_DYRK1A_RPxSP_1	566	570	PF00069	0.612
MOD_DYRK1A_RPxSP_1	674	678	PF00069	0.649
MOD_GlcNHglycan	250	253	PF01048	0.754
MOD_GlcNHglycan	262	265	PF01048	0.552
MOD_GlcNHglycan	334	337	PF01048	0.766
MOD_GlcNHglycan	357	360	PF01048	0.632
MOD_GlcNHglycan	453	456	PF01048	0.710
MOD_GlcNHglycan	472	475	PF01048	0.704
MOD_GlcNHglycan	476	479	PF01048	0.641
MOD_GlcNHglycan	497	500	PF01048	0.687
MOD_GlcNHglycan	505	508	PF01048	0.685
MOD_GlcNHglycan	519	522	PF01048	0.538
MOD_GlcNHglycan	538	541	PF01048	0.747
MOD_GlcNHglycan	544	547	PF01048	0.532
MOD_GlcNHglycan	619	622	PF01048	0.590
MOD_GlcNHglycan	646	649	PF01048	0.757
MOD_GlcNHglycan	652	655	PF01048	0.691
MOD_GlcNHglycan	656	659	PF01048	0.639
MOD_GlcNHglycan	674	677	PF01048	0.829
MOD_GlcNHglycan	697	700	PF01048	0.666
MOD_GlcNHglycan	714	717	PF01048	0.647
MOD_GlcNHglycan	725	728	PF01048	0.583
MOD_GlcNHglycan	729	732	PF01048	0.810
MOD_GlcNHglycan	757	760	PF01048	0.524
MOD_GSK3_1	163	170	PF00069	0.622
MOD_GSK3_1	236	243	PF00069	0.608
MOD_GSK3_1	344	351	PF00069	0.635
MOD_GSK3_1	354	361	PF00069	0.612
MOD_GSK3_1	431	438	PF00069	0.581
MOD_GSK3_1	460	467	PF00069	0.769
MOD_GSK3_1	470	477	PF00069	0.669
MOD_GSK3_1	513	520	PF00069	0.767
MOD_GSK3_1	542	549	PF00069	0.625
MOD_GSK3_1	562	569	PF00069	0.630
MOD_GSK3_1	650	657	PF00069	0.611
MOD_GSK3_1	674	681	PF00069	0.655
MOD_GSK3_1	682	689	PF00069	0.702
MOD_GSK3_1	695	702	PF00069	0.656
MOD_GSK3_1	705	712	PF00069	0.604
MOD_GSK3_1	719	726	PF00069	0.542
MOD_GSK3_1	751	758	PF00069	0.465
MOD_LATS_1	670	676	PF00433	0.570
MOD_N-GLC_1	361	366	PF02516	0.693
MOD_N-GLC_1	650	655	PF02516	0.572
MOD_NEK2_1	162	167	PF00069	0.575
MOD_NEK2_1	431	436	PF00069	0.517
MOD_NEK2_1	682	687	PF00069	0.634
MOD_PIKK_1	121	127	PF00454	0.451
MOD_PKA_1	643	649	PF00069	0.647
MOD_PKA_1	672	678	PF00069	0.565
MOD_PKA_2	143	149	PF00069	0.510
MOD_PKA_2	181	187	PF00069	0.663
MOD_PKA_2	188	194	PF00069	0.616
MOD_PKA_2	221	227	PF00069	0.580
MOD_PKA_2	240	246	PF00069	0.592
MOD_PKA_2	495	501	PF00069	0.633
MOD_PKA_2	535	541	PF00069	0.647
MOD_PKA_2	542	548	PF00069	0.529
MOD_PKA_2	562	568	PF00069	0.670
MOD_PKA_2	643	649	PF00069	0.707
MOD_PKA_2	672	678	PF00069	0.628
MOD_PKB_1	753	761	PF00069	0.501
MOD_Plk_1	626	632	PF00069	0.662
MOD_Plk_4	163	169	PF00069	0.600
MOD_Plk_4	292	298	PF00069	0.541
MOD_Plk_4	658	664	PF00069	0.641
MOD_ProDKin_1	213	219	PF00069	0.671
MOD_ProDKin_1	361	367	PF00069	0.613
MOD_ProDKin_1	374	380	PF00069	0.562
MOD_ProDKin_1	444	450	PF00069	0.668
MOD_ProDKin_1	458	464	PF00069	0.802
MOD_ProDKin_1	513	519	PF00069	0.646
MOD_ProDKin_1	550	556	PF00069	0.696
MOD_ProDKin_1	566	572	PF00069	0.639
MOD_ProDKin_1	582	588	PF00069	0.523
MOD_ProDKin_1	598	604	PF00069	0.605
MOD_ProDKin_1	652	658	PF00069	0.721
MOD_ProDKin_1	674	680	PF00069	0.739
MOD_ProDKin_1	699	705	PF00069	0.640
MOD_SUMO_for_1	389	392	PF00179	0.517
TRG_DiLeu_BaEn_4	522	528	PF01217	0.620
TRG_DiLeu_BaEn_4	579	585	PF01217	0.678
TRG_ER_diArg_1	114	117	PF00400	0.462
TRG_ER_diArg_1	15	17	PF00400	0.425
TRG_ER_diArg_1	218	220	PF00400	0.655
TRG_ER_diArg_1	297	299	PF00400	0.418
TRG_ER_diArg_1	370	372	PF00400	0.656
TRG_ER_diArg_1	414	416	PF00400	0.658
TRG_ER_diArg_1	479	482	PF00400	0.771
TRG_ER_diArg_1	672	674	PF00400	0.693
TRG_ER_diArg_1	750	753	PF00400	0.502
TRG_NES_CRM1_1	430	442	PF08389	0.584
TRG_Pf-PMV_PEXEL_1	108	112	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	303	307	PF00026	0.500
TRG_Pf-PMV_PEXEL_1	489	494	PF00026	0.656
TRG_Pf-PMV_PEXEL_1	54	59	PF00026	0.485
TRG_Pf-PMV_PEXEL_1	614	618	PF00026	0.632

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWW2	Leptomonas seymouri	43%	100%
A0A3S7WNZ4	Leishmania donovani	87%	100%
A4H463	Leishmania braziliensis	66%	100%
A4HSD2	Leishmania infantum	88%	100%
E9AKC1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%