Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QJG5_LEIMA

TriTrypDb:

LmjF.05.0370 , LMJLV39_050008600 , LMJSD75_050008600

Length:

328

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJG5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.737
CLV_NRD_NRD_1	246	248	PF00675	0.804
CLV_NRD_NRD_1	38	40	PF00675	0.652
CLV_PCSK_KEX2_1	246	248	PF00082	0.709
CLV_PCSK_KEX2_1	37	39	PF00082	0.677
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.677
CLV_PCSK_PC7_1	33	39	PF00082	0.649
CLV_PCSK_SKI1_1	129	133	PF00082	0.589
CLV_PCSK_SKI1_1	247	251	PF00082	0.684
DEG_SPOP_SBC_1	180	184	PF00917	0.839
DEG_SPOP_SBC_1	217	221	PF00917	0.727
DEG_SPOP_SBC_1	254	258	PF00917	0.664
DOC_MAPK_gen_1	246	254	PF00069	0.572
DOC_MAPK_MEF2A_6	246	254	PF00069	0.572
DOC_MAPK_NFAT4_5	247	255	PF00069	0.572
DOC_PP1_RVXF_1	127	134	PF00149	0.646
DOC_PP4_FxxP_1	12	15	PF00568	0.786
DOC_PP4_FxxP_1	222	225	PF00568	0.713
DOC_PP4_FxxP_1	52	55	PF00568	0.754
DOC_USP7_MATH_1	180	184	PF00917	0.839
DOC_USP7_MATH_1	216	220	PF00917	0.712
DOC_USP7_MATH_1	255	259	PF00917	0.585
DOC_USP7_MATH_1	268	272	PF00917	0.551
DOC_USP7_MATH_1	98	102	PF00917	0.713
DOC_WW_Pin1_4	181	186	PF00397	0.815
DOC_WW_Pin1_4	239	244	PF00397	0.617
DOC_WW_Pin1_4	309	314	PF00397	0.709
LIG_14-3-3_CanoR_1	247	253	PF00244	0.775
LIG_14-3-3_CanoR_1	85	94	PF00244	0.828
LIG_BRCT_BRCA1_1	218	222	PF00533	0.814
LIG_Clathr_ClatBox_1	132	136	PF01394	0.757
LIG_eIF4E_1	16	22	PF01652	0.662
LIG_FHA_1	17	23	PF00498	0.760
LIG_FHA_1	72	78	PF00498	0.661
LIG_FHA_2	147	153	PF00498	0.572
LIG_FHA_2	310	316	PF00498	0.694
LIG_IBAR_NPY_1	14	16	PF08397	0.779
LIG_LIR_Apic_2	10	15	PF02991	0.790
LIG_LIR_Apic_2	219	225	PF02991	0.705
LIG_LIR_Nem_3	152	157	PF02991	0.596
LIG_MAD2	129	137	PF02301	0.715
LIG_SH2_CRK	205	209	PF00017	0.764
LIG_SH2_NCK_1	205	209	PF00017	0.623
LIG_SH2_STAP1	75	79	PF00017	0.651
LIG_SH3_3	135	141	PF00018	0.650
LIG_SH3_3	222	228	PF00018	0.658
LIG_SH3_3	280	286	PF00018	0.760
MOD_CDK_SPxxK_3	239	246	PF00069	0.611
MOD_CK1_1	118	124	PF00069	0.752
MOD_CK1_1	270	276	PF00069	0.737
MOD_CK2_1	309	315	PF00069	0.691
MOD_GlcNHglycan	117	120	PF01048	0.773
MOD_GlcNHglycan	175	178	PF01048	0.759
MOD_GlcNHglycan	270	273	PF01048	0.702
MOD_GlcNHglycan	7	10	PF01048	0.798
MOD_GlcNHglycan	90	93	PF01048	0.833
MOD_GlcNHglycan	95	99	PF01048	0.797
MOD_GSK3_1	115	122	PF00069	0.729
MOD_GSK3_1	146	153	PF00069	0.596
MOD_GSK3_1	175	182	PF00069	0.697
MOD_GSK3_1	235	242	PF00069	0.640
MOD_GSK3_1	256	263	PF00069	0.716
MOD_GSK3_1	266	273	PF00069	0.641
MOD_GSK3_1	94	101	PF00069	0.784
MOD_N-GLC_1	162	167	PF02516	0.618
MOD_N-GLC_1	17	22	PF02516	0.680
MOD_NEK2_1	104	109	PF00069	0.741
MOD_NEK2_1	204	209	PF00069	0.669
MOD_NEK2_1	260	265	PF00069	0.687
MOD_NEK2_1	267	272	PF00069	0.595
MOD_NEK2_1	70	75	PF00069	0.654
MOD_NEK2_2	218	223	PF00069	0.703
MOD_PIKK_1	83	89	PF00454	0.741
MOD_PKA_2	104	110	PF00069	0.747
MOD_Plk_1	17	23	PF00069	0.679
MOD_Plk_1	235	241	PF00069	0.599
MOD_Plk_2-3	162	168	PF00069	0.557
MOD_Plk_4	17	23	PF00069	0.658
MOD_Plk_4	99	105	PF00069	0.807
MOD_ProDKin_1	181	187	PF00069	0.817
MOD_ProDKin_1	239	245	PF00069	0.611
MOD_ProDKin_1	309	315	PF00069	0.708
TRG_ENDOCYTIC_2	154	157	PF00928	0.601
TRG_ENDOCYTIC_2	205	208	PF00928	0.625
TRG_ER_diArg_1	245	247	PF00400	0.717
TRG_ER_diArg_1	289	292	PF00400	0.749
TRG_Pf-PMV_PEXEL_1	202	206	PF00026	0.703

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3H3	Leptomonas seymouri	36%	100%
A0A3S7WP10	Leishmania donovani	91%	100%
A4H482	Leishmania braziliensis	67%	98%
A4HSF9	Leishmania infantum	91%	100%
E9AKE3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%