Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QJF5_LEIMA

TriTrypDb:

LmjF.05.0470 , LMJLV39_050009600 , LMJSD75_050009800

Length:

343

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJF5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJF5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	146	150	PF00656	0.565
CLV_C14_Caspase3-7	300	304	PF00656	0.675
CLV_NRD_NRD_1	289	291	PF00675	0.700
CLV_NRD_NRD_1	292	294	PF00675	0.653
CLV_NRD_NRD_1	311	313	PF00675	0.377
CLV_NRD_NRD_1	324	326	PF00675	0.501
CLV_NRD_NRD_1	330	332	PF00675	0.450
CLV_NRD_NRD_1	65	67	PF00675	0.447
CLV_NRD_NRD_1	80	82	PF00675	0.475
CLV_NRD_NRD_1	88	90	PF00675	0.425
CLV_PCSK_FUR_1	290	294	PF00082	0.702
CLV_PCSK_FUR_1	328	332	PF00082	0.716
CLV_PCSK_KEX2_1	243	245	PF00082	0.848
CLV_PCSK_KEX2_1	289	291	PF00082	0.700
CLV_PCSK_KEX2_1	292	294	PF00082	0.653
CLV_PCSK_KEX2_1	311	313	PF00082	0.377
CLV_PCSK_KEX2_1	330	332	PF00082	0.450
CLV_PCSK_KEX2_1	65	67	PF00082	0.447
CLV_PCSK_KEX2_1	80	82	PF00082	0.475
CLV_PCSK_KEX2_1	88	90	PF00082	0.425
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.848
CLV_PCSK_SKI1_1	251	255	PF00082	0.839
CLV_PCSK_SKI1_1	292	296	PF00082	0.693
CLV_Separin_Metazoa	315	319	PF03568	0.683
DEG_APCC_DBOX_1	291	299	PF00400	0.691
DEG_Kelch_Keap1_1	74	79	PF01344	0.488
DEG_SPOP_SBC_1	34	38	PF00917	0.456
DOC_CYCLIN_RxL_1	289	301	PF00134	0.692
DOC_CYCLIN_yCln2_LP_2	225	231	PF00134	0.779
DOC_MAPK_gen_1	289	297	PF00069	0.695
DOC_MAPK_MEF2A_6	26	33	PF00069	0.473
DOC_PP1_RVXF_1	291	298	PF00149	0.691
DOC_USP7_MATH_1	100	104	PF00917	0.426
DOC_USP7_MATH_1	213	217	PF00917	0.672
DOC_USP7_MATH_1	242	246	PF00917	0.821
DOC_USP7_MATH_1	249	253	PF00917	0.677
DOC_WW_Pin1_4	15	20	PF00397	0.467
DOC_WW_Pin1_4	220	225	PF00397	0.819
DOC_WW_Pin1_4	251	256	PF00397	0.762
DOC_WW_Pin1_4	46	51	PF00397	0.437
LIG_14-3-3_CanoR_1	208	215	PF00244	0.723
LIG_14-3-3_CanoR_1	244	253	PF00244	0.848
LIG_14-3-3_CanoR_1	41	45	PF00244	0.465
LIG_14-3-3_CanoR_1	80	90	PF00244	0.466
LIG_Actin_WH2_2	57	75	PF00022	0.441
LIG_BRCT_BRCA1_1	140	144	PF00533	0.551
LIG_BRCT_BRCA1_1	26	30	PF00533	0.473
LIG_FHA_1	177	183	PF00498	0.749
LIG_FHA_1	82	88	PF00498	0.470
LIG_FHA_2	260	266	PF00498	0.837
LIG_GBD_Chelix_1	113	121	PF00786	0.684
LIG_LIR_Gen_1	27	35	PF02991	0.468
LIG_LIR_Nem_3	25	31	PF02991	0.471
LIG_MYND_1	236	240	PF01753	0.680
LIG_Pex14_2	92	96	PF04695	0.417
LIG_SH2_CRK	131	135	PF00017	0.511
LIG_SH2_GRB2like	305	308	PF00017	0.668
LIG_SH2_STAP1	131	135	PF00017	0.511
LIG_SH2_STAT5	305	308	PF00017	0.668
LIG_SH2_STAT5	4	7	PF00017	0.470
LIG_SH3_1	233	239	PF00018	0.623
LIG_SH3_2	239	244	PF14604	0.682
LIG_SH3_3	199	205	PF00018	0.679
LIG_SH3_3	231	237	PF00018	0.827
LIG_SH3_3	274	280	PF00018	0.790
LIG_SUMO_SIM_par_1	173	180	PF11976	0.587
LIG_WRC_WIRS_1	30	35	PF05994	0.469
LIG_WW_2	236	239	PF00397	0.619
MOD_CDK_SPK_2	251	256	PF00069	0.779
MOD_CK1_1	103	109	PF00069	0.580
MOD_CK1_1	216	222	PF00069	0.820
MOD_CK1_1	245	251	PF00069	0.711
MOD_GlcNHglycan	185	188	PF01048	0.757
MOD_GlcNHglycan	209	212	PF01048	0.716
MOD_GlcNHglycan	244	247	PF01048	0.851
MOD_GlcNHglycan	281	284	PF01048	0.596
MOD_GlcNHglycan	46	49	PF01048	0.474
MOD_GSK3_1	213	220	PF00069	0.779
MOD_GSK3_1	245	252	PF00069	0.653
MOD_GSK3_1	29	36	PF00069	0.465
MOD_GSK3_1	40	47	PF00069	0.459
MOD_GSK3_1	99	106	PF00069	0.423
MOD_N-GLC_1	103	108	PF02516	0.720
MOD_NEK2_1	207	212	PF00069	0.710
MOD_NEK2_1	229	234	PF00069	0.805
MOD_NEK2_1	44	49	PF00069	0.447
MOD_NEK2_1	59	64	PF00069	0.454
MOD_PIKK_1	81	87	PF00454	0.474
MOD_PKA_1	80	86	PF00069	0.482
MOD_PKA_2	207	213	PF00069	0.741
MOD_PKA_2	40	46	PF00069	0.458
MOD_PKA_2	80	86	PF00069	0.482
MOD_Plk_1	103	109	PF00069	0.722
MOD_Plk_1	60	66	PF00069	0.426
MOD_Plk_2-3	143	149	PF00069	0.549
MOD_Plk_4	149	155	PF00069	0.780
MOD_Plk_4	35	41	PF00069	0.461
MOD_ProDKin_1	15	21	PF00069	0.467
MOD_ProDKin_1	220	226	PF00069	0.819
MOD_ProDKin_1	251	257	PF00069	0.754
MOD_ProDKin_1	46	52	PF00069	0.432
MOD_SUMO_for_1	283	286	PF00179	0.574
TRG_DiLeu_BaLyEn_6	51	56	PF01217	0.428
TRG_ENDOCYTIC_2	131	134	PF00928	0.517
TRG_ER_diArg_1	289	292	PF00400	0.703
TRG_ER_diArg_1	328	331	PF00400	0.693
TRG_ER_diArg_1	64	66	PF00400	0.440
TRG_ER_diArg_1	87	89	PF00400	0.443
TRG_NLS_Bipartite_1	311	329	PF00514	0.695
TRG_Pf-PMV_PEXEL_1	296	300	PF00026	0.685

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H5I0	Leishmania donovani	90%	100%
A4HSG9	Leishmania infantum	90%	100%
E9AKF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%