Stomatin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

stomatin-like protein

Species:

Leishmania major

UniProt:

Q4QJ98_LEIMA

TriTrypDb:

LmjF.05.1040 , LMJLV39_050015500 , LMJSD75_050015900

Length:

357

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	2
GO:0005886	plasma membrane	3	2
GO:0016020	membrane	2	12
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	12

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Expansion

Sequence features

Q4QJ98

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ98

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	186	188	PF00675	0.310
CLV_NRD_NRD_1	211	213	PF00675	0.267
CLV_NRD_NRD_1	221	223	PF00675	0.238
CLV_NRD_NRD_1	224	226	PF00675	0.231
CLV_NRD_NRD_1	3	5	PF00675	0.503
CLV_PCSK_FUR_1	222	226	PF00082	0.249
CLV_PCSK_KEX2_1	186	188	PF00082	0.294
CLV_PCSK_KEX2_1	197	199	PF00082	0.288
CLV_PCSK_KEX2_1	211	213	PF00082	0.272
CLV_PCSK_KEX2_1	224	226	PF00082	0.261

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTU5	Leptomonas seymouri	85%	99%
A0A0S4INS2	Bodo saltans	62%	100%
A0A1X0NKE1	Trypanosomatidae	70%	83%
A0A3R7M6V7	Trypanosoma rangeli	63%	93%
A0A3S5H5L4	Leishmania donovani	99%	100%
A4H4E9	Leishmania braziliensis	93%	100%
A4HSM6	Leishmania infantum	99%	100%
C9ZND8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	67%
E9AKL0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
E9AS80	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%

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