Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4QJ97_LEIMA

TriTrypDb:

LmjF.05.1050 , LMJLV39_050015700

Length:

443

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJ97

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ97

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	250	254	PF00656	0.570
CLV_C14_Caspase3-7	94	98	PF00656	0.551
CLV_NRD_NRD_1	139	141	PF00675	0.545
CLV_NRD_NRD_1	155	157	PF00675	0.571
CLV_NRD_NRD_1	291	293	PF00675	0.493
CLV_NRD_NRD_1	355	357	PF00675	0.459
CLV_NRD_NRD_1	362	364	PF00675	0.441
CLV_NRD_NRD_1	426	428	PF00675	0.497
CLV_PCSK_KEX2_1	138	140	PF00082	0.548
CLV_PCSK_KEX2_1	155	157	PF00082	0.402
CLV_PCSK_KEX2_1	290	292	PF00082	0.539
CLV_PCSK_KEX2_1	321	323	PF00082	0.439
CLV_PCSK_KEX2_1	355	357	PF00082	0.459
CLV_PCSK_KEX2_1	362	364	PF00082	0.441
CLV_PCSK_KEX2_1	426	428	PF00082	0.497
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.548
CLV_PCSK_PC1ET2_1	290	292	PF00082	0.686
CLV_PCSK_PC1ET2_1	321	323	PF00082	0.440
CLV_PCSK_SKI1_1	11	15	PF00082	0.635
CLV_PCSK_SKI1_1	347	351	PF00082	0.464
CLV_PCSK_SKI1_1	372	376	PF00082	0.503
CLV_PCSK_SKI1_1	418	422	PF00082	0.508
CLV_PCSK_SKI1_1	74	78	PF00082	0.687
DEG_Nend_Nbox_1	1	3	PF02207	0.630
DOC_ANK_TNKS_1	328	335	PF00023	0.551
DOC_CYCLIN_RxL_1	74	84	PF00134	0.533
DOC_PP2B_LxvP_1	55	58	PF13499	0.770
DOC_PP2B_LxvP_1	7	10	PF13499	0.630
DOC_USP7_MATH_1	108	112	PF00917	0.566
DOC_USP7_MATH_1	332	336	PF00917	0.547
DOC_USP7_UBL2_3	317	321	PF12436	0.432
DOC_WW_Pin1_4	223	228	PF00397	0.578
DOC_WW_Pin1_4	29	34	PF00397	0.553
LIG_14-3-3_CanoR_1	291	296	PF00244	0.686
LIG_14-3-3_CanoR_1	322	326	PF00244	0.488
LIG_14-3-3_CanoR_1	329	337	PF00244	0.549
LIG_14-3-3_CanoR_1	363	369	PF00244	0.443
LIG_14-3-3_CanoR_1	50	54	PF00244	0.663
LIG_Actin_WH2_2	409	425	PF00022	0.508
LIG_APCC_ABBA_1	371	376	PF00400	0.513
LIG_BIR_III_4	253	257	PF00653	0.567
LIG_deltaCOP1_diTrp_1	333	341	PF00928	0.481
LIG_FHA_1	100	106	PF00498	0.612
LIG_FHA_1	14	20	PF00498	0.526
LIG_FHA_1	2	8	PF00498	0.639
LIG_FHA_1	415	421	PF00498	0.512
LIG_FHA_1	50	56	PF00498	0.626
LIG_FHA_1	66	72	PF00498	0.469
LIG_FHA_2	116	122	PF00498	0.524
LIG_FHA_2	188	194	PF00498	0.455
LIG_FHA_2	245	251	PF00498	0.669
LIG_FHA_2	401	407	PF00498	0.562
LIG_LIR_Gen_1	111	120	PF02991	0.489
LIG_LIR_Gen_1	274	285	PF02991	0.530
LIG_LIR_Gen_1	294	304	PF02991	0.542
LIG_LIR_Nem_3	111	116	PF02991	0.485
LIG_LIR_Nem_3	274	280	PF02991	0.525
LIG_LIR_Nem_3	294	299	PF02991	0.688
LIG_LIR_Nem_3	431	435	PF02991	0.678
LIG_NRBOX	75	81	PF00104	0.537
LIG_PCNA_yPIPBox_3	123	136	PF02747	0.485
LIG_PCNA_yPIPBox_3	229	239	PF02747	0.450
LIG_PCNA_yPIPBox_3	67	80	PF02747	0.515
LIG_RPA_C_Fungi	301	313	PF08784	0.422
LIG_SH2_GRB2like	203	206	PF00017	0.443
LIG_SH2_STAP1	192	196	PF00017	0.466
LIG_SH2_STAP1	277	281	PF00017	0.469
LIG_SH2_STAP1	296	300	PF00017	0.482
LIG_SH2_STAP1	326	330	PF00017	0.496
LIG_SH2_STAP1	353	357	PF00017	0.506
LIG_SH2_STAT3	269	272	PF00017	0.472
LIG_SH2_STAT5	269	272	PF00017	0.472
LIG_SH3_3	27	33	PF00018	0.630
LIG_SH3_3	51	57	PF00018	0.592
MOD_CDK_SPxK_1	223	229	PF00069	0.577
MOD_CK1_1	115	121	PF00069	0.465
MOD_CK1_1	29	35	PF00069	0.612
MOD_CK1_1	391	397	PF00069	0.544
MOD_CK1_1	45	51	PF00069	0.619
MOD_CK2_1	108	114	PF00069	0.507
MOD_CK2_1	115	121	PF00069	0.488
MOD_CK2_1	187	193	PF00069	0.454
MOD_CK2_1	291	297	PF00069	0.542
MOD_CK2_1	59	65	PF00069	0.571
MOD_GlcNHglycan	16	19	PF01048	0.642
MOD_GlcNHglycan	40	43	PF01048	0.627
MOD_GlcNHglycan	44	47	PF01048	0.644
MOD_GlcNHglycan	83	86	PF01048	0.519
MOD_GSK3_1	108	115	PF00069	0.481
MOD_GSK3_1	14	21	PF00069	0.761
MOD_GSK3_1	317	324	PF00069	0.587
MOD_GSK3_1	328	335	PF00069	0.507
MOD_GSK3_1	38	45	PF00069	0.650
MOD_LATS_1	319	325	PF00433	0.434
MOD_N-GLC_2	346	348	PF02516	0.464
MOD_NEK2_1	1	6	PF00069	0.637
MOD_NEK2_1	106	111	PF00069	0.647
MOD_NEK2_1	112	117	PF00069	0.486
MOD_NEK2_1	244	249	PF00069	0.518
MOD_NEK2_1	349	354	PF00069	0.523
MOD_NEK2_1	79	84	PF00069	0.543
MOD_NEK2_2	108	113	PF00069	0.509
MOD_PKA_1	291	297	PF00069	0.542
MOD_PKA_1	321	327	PF00069	0.432
MOD_PKA_2	106	112	PF00069	0.521
MOD_PKA_2	187	193	PF00069	0.454
MOD_PKA_2	291	297	PF00069	0.542
MOD_PKA_2	321	327	PF00069	0.480
MOD_PKA_2	328	334	PF00069	0.511
MOD_PKA_2	49	55	PF00069	0.665
MOD_Plk_1	244	250	PF00069	0.544
MOD_Plk_1	26	32	PF00069	0.630
MOD_Plk_1	388	394	PF00069	0.557
MOD_Plk_4	108	114	PF00069	0.534
MOD_Plk_4	291	297	PF00069	0.678
MOD_Plk_4	321	327	PF00069	0.534
MOD_Plk_4	332	338	PF00069	0.487
MOD_Plk_4	400	406	PF00069	0.554
MOD_ProDKin_1	223	229	PF00069	0.577
MOD_ProDKin_1	29	35	PF00069	0.552
MOD_SUMO_rev_2	152	161	PF00179	0.512
TRG_DiLeu_BaEn_2	130	136	PF01217	0.541
TRG_ENDOCYTIC_2	277	280	PF00928	0.525
TRG_ENDOCYTIC_2	296	299	PF00928	0.479
TRG_ER_diArg_1	139	141	PF00400	0.532
TRG_ER_diArg_1	154	156	PF00400	0.622
TRG_ER_diArg_1	210	213	PF00400	0.518
TRG_ER_diArg_1	362	364	PF00400	0.441
TRG_ER_diArg_1	426	428	PF00400	0.497
TRG_NLS_MonoCore_2	289	294	PF00514	0.542
TRG_Pf-PMV_PEXEL_1	123	127	PF00026	0.480
TRG_Pf-PMV_PEXEL_1	74	78	PF00026	0.544

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3V2	Leptomonas seymouri	66%	100%
A0A3S5H5L5	Leishmania donovani	97%	100%
A4H4F0	Leishmania braziliensis	84%	86%
A4HSM7	Leishmania infantum	96%	100%
E9AKL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%