LeishMANIAdb
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Putative 5'-3' exonuclease

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 5'-3' exonuclease
Gene product:
5'-3' exoribonuclease A, putative
Species:
Leishmania major
UniProt:
Q4QJ53_LEIMA
TriTrypDb:
LmjF.06.0260 , LMJLV39_060007700 * , LMJSD75_060007700
Length:
1490

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 8
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

Q4QJ53
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0000956 nuclear-transcribed mRNA catabolic process 7 11
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006401 RNA catabolic process 5 11
GO:0006402 mRNA catabolic process 6 11
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009056 catabolic process 2 11
GO:0009057 macromolecule catabolic process 4 11
GO:0009892 negative regulation of metabolic process 4 11
GO:0009987 cellular process 1 12
GO:0010468 regulation of gene expression 5 11
GO:0010605 negative regulation of macromolecule metabolic process 5 11
GO:0010629 negative regulation of gene expression 6 11
GO:0016070 RNA metabolic process 5 12
GO:0016071 mRNA metabolic process 6 11
GO:0019222 regulation of metabolic process 3 11
GO:0019439 aromatic compound catabolic process 4 11
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0034655 nucleobase-containing compound catabolic process 4 11
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044248 cellular catabolic process 3 11
GO:0044260 obsolete cellular macromolecule metabolic process 3 11
GO:0044265 obsolete cellular macromolecule catabolic process 4 11
GO:0044270 cellular nitrogen compound catabolic process 4 11
GO:0046483 heterocycle metabolic process 3 12
GO:0046700 heterocycle catabolic process 4 11
GO:0048519 negative regulation of biological process 3 11
GO:0050789 regulation of biological process 2 11
GO:0060255 regulation of macromolecule metabolic process 4 11
GO:0065007 biological regulation 1 11
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1901361 organic cyclic compound catabolic process 4 11
GO:1901575 organic substance catabolic process 3 11
GO:0006508 proteolysis 4 1
GO:0019538 protein metabolic process 3 1
GO:1901564 organonitrogen compound metabolic process 3 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 2
GO:0003824 catalytic activity 1 12
GO:0004518 nuclease activity 4 12
GO:0004527 exonuclease activity 5 12
GO:0004532 RNA exonuclease activity 5 2
GO:0004534 5'-3' RNA exonuclease activity 7 2
GO:0004540 RNA nuclease activity 4 2
GO:0005488 binding 1 12
GO:0008409 5'-3' exonuclease activity 6 11
GO:0016787 hydrolase activity 2 12
GO:0016788 hydrolase activity, acting on ester bonds 3 12
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6 2
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6 2
GO:0097159 organic cyclic compound binding 2 12
GO:0140098 catalytic activity, acting on RNA 3 2
GO:0140640 catalytic activity, acting on a nucleic acid 2 2
GO:1901363 heterocyclic compound binding 2 12
GO:0004175 endopeptidase activity 4 1
GO:0004190 aspartic-type endopeptidase activity 5 1
GO:0008233 peptidase activity 3 1
GO:0070001 aspartic-type peptidase activity 4 1
GO:0140096 catalytic activity, acting on a protein 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1175 1179 PF00656 0.538
CLV_C14_Caspase3-7 1426 1430 PF00656 0.522
CLV_C14_Caspase3-7 660 664 PF00656 0.538
CLV_C14_Caspase3-7 703 707 PF00656 0.387
CLV_C14_Caspase3-7 815 819 PF00656 0.472
CLV_NRD_NRD_1 100 102 PF00675 0.234
CLV_NRD_NRD_1 1433 1435 PF00675 0.614
CLV_NRD_NRD_1 1474 1476 PF00675 0.531
CLV_NRD_NRD_1 188 190 PF00675 0.234
CLV_NRD_NRD_1 235 237 PF00675 0.455
CLV_NRD_NRD_1 371 373 PF00675 0.267
CLV_NRD_NRD_1 385 387 PF00675 0.193
CLV_NRD_NRD_1 429 431 PF00675 0.338
CLV_NRD_NRD_1 52 54 PF00675 0.338
CLV_NRD_NRD_1 604 606 PF00675 0.346
CLV_NRD_NRD_1 77 79 PF00675 0.259
CLV_NRD_NRD_1 774 776 PF00675 0.245
CLV_PCSK_FUR_1 383 387 PF00082 0.303
CLV_PCSK_FUR_1 98 102 PF00082 0.234
CLV_PCSK_KEX2_1 100 102 PF00082 0.234
CLV_PCSK_KEX2_1 1011 1013 PF00082 0.320
CLV_PCSK_KEX2_1 1310 1312 PF00082 0.691
CLV_PCSK_KEX2_1 1433 1435 PF00082 0.673
CLV_PCSK_KEX2_1 187 189 PF00082 0.234
CLV_PCSK_KEX2_1 370 372 PF00082 0.269
CLV_PCSK_KEX2_1 385 387 PF00082 0.188
CLV_PCSK_KEX2_1 429 431 PF00082 0.274
CLV_PCSK_KEX2_1 52 54 PF00082 0.338
CLV_PCSK_KEX2_1 604 606 PF00082 0.346
CLV_PCSK_KEX2_1 640 642 PF00082 0.284
CLV_PCSK_KEX2_1 697 699 PF00082 0.263
CLV_PCSK_PC1ET2_1 1011 1013 PF00082 0.352
CLV_PCSK_PC1ET2_1 1310 1312 PF00082 0.697
CLV_PCSK_PC1ET2_1 640 642 PF00082 0.301
CLV_PCSK_PC1ET2_1 697 699 PF00082 0.267
CLV_PCSK_SKI1_1 1092 1096 PF00082 0.473
CLV_PCSK_SKI1_1 126 130 PF00082 0.259
CLV_PCSK_SKI1_1 341 345 PF00082 0.276
CLV_PCSK_SKI1_1 454 458 PF00082 0.277
CLV_PCSK_SKI1_1 550 554 PF00082 0.245
CLV_PCSK_SKI1_1 599 603 PF00082 0.417
CLV_PCSK_SKI1_1 670 674 PF00082 0.355
CLV_PCSK_SKI1_1 687 691 PF00082 0.366
CLV_PCSK_SKI1_1 709 713 PF00082 0.304
CLV_PCSK_SKI1_1 746 750 PF00082 0.338
CLV_PCSK_SKI1_1 79 83 PF00082 0.245
CLV_PCSK_SKI1_1 957 961 PF00082 0.506
CLV_Separin_Metazoa 873 877 PF03568 0.460
DEG_APCC_DBOX_1 1474 1482 PF00400 0.647
DEG_SCF_FBW7_1 1061 1068 PF00400 0.550
DEG_SCF_TRCP1_1 1274 1280 PF00400 0.610
DEG_SPOP_SBC_1 1362 1366 PF00917 0.729
DEG_SPOP_SBC_1 1387 1391 PF00917 0.690
DEG_SPOP_SBC_1 392 396 PF00917 0.418
DOC_CKS1_1 1167 1172 PF01111 0.576
DOC_CKS1_1 136 141 PF01111 0.538
DOC_CKS1_1 17 22 PF01111 0.445
DOC_CYCLIN_yCln2_LP_2 482 488 PF00134 0.460
DOC_CYCLIN_yCln2_LP_2 875 881 PF00134 0.390
DOC_MAPK_DCC_7 888 898 PF00069 0.436
DOC_MAPK_gen_1 100 110 PF00069 0.434
DOC_MAPK_gen_1 1433 1441 PF00069 0.553
DOC_MAPK_gen_1 284 293 PF00069 0.448
DOC_MAPK_gen_1 658 667 PF00069 0.477
DOC_MAPK_gen_1 746 756 PF00069 0.442
DOC_MAPK_gen_1 78 85 PF00069 0.445
DOC_MAPK_gen_1 833 841 PF00069 0.443
DOC_MAPK_MEF2A_6 258 267 PF00069 0.313
DOC_MAPK_MEF2A_6 271 278 PF00069 0.234
DOC_MAPK_MEF2A_6 284 293 PF00069 0.315
DOC_MAPK_MEF2A_6 661 669 PF00069 0.434
DOC_MAPK_MEF2A_6 749 756 PF00069 0.445
DOC_MAPK_MEF2A_6 923 931 PF00069 0.361
DOC_MAPK_NFAT4_5 271 279 PF00069 0.296
DOC_MAPK_NFAT4_5 749 757 PF00069 0.481
DOC_MAPK_RevD_3 64 79 PF00069 0.538
DOC_PP1_RVXF_1 1228 1235 PF00149 0.559
DOC_PP1_RVXF_1 179 186 PF00149 0.442
DOC_PP1_RVXF_1 361 367 PF00149 0.518
DOC_PP2B_LxvP_1 1122 1125 PF13499 0.404
DOC_PP2B_LxvP_1 502 505 PF13499 0.538
DOC_PP2B_LxvP_1 875 878 PF13499 0.345
DOC_PP2B_PxIxI_1 315 321 PF00149 0.481
DOC_PP4_FxxP_1 1260 1263 PF00568 0.556
DOC_PP4_FxxP_1 656 659 PF00568 0.441
DOC_PP4_FxxP_1 871 874 PF00568 0.442
DOC_SPAK_OSR1_1 1450 1454 PF12202 0.411
DOC_USP7_MATH_1 1272 1276 PF00917 0.594
DOC_USP7_MATH_1 1277 1281 PF00917 0.577
DOC_USP7_MATH_1 1285 1289 PF00917 0.494
DOC_USP7_MATH_1 1347 1351 PF00917 0.538
DOC_USP7_MATH_1 1363 1367 PF00917 0.576
DOC_USP7_MATH_1 1392 1396 PF00917 0.573
DOC_USP7_MATH_1 1415 1419 PF00917 0.602
DOC_USP7_MATH_1 1427 1431 PF00917 0.689
DOC_USP7_MATH_1 285 289 PF00917 0.326
DOC_USP7_MATH_1 399 403 PF00917 0.343
DOC_USP7_MATH_1 463 467 PF00917 0.434
DOC_USP7_MATH_1 476 480 PF00917 0.434
DOC_USP7_MATH_1 555 559 PF00917 0.459
DOC_USP7_MATH_1 707 711 PF00917 0.409
DOC_USP7_MATH_1 983 987 PF00917 0.526
DOC_USP7_UBL2_3 248 252 PF12436 0.470
DOC_USP7_UBL2_3 254 258 PF12436 0.296
DOC_USP7_UBL2_3 705 709 PF12436 0.538
DOC_WW_Pin1_4 1061 1066 PF00397 0.493
DOC_WW_Pin1_4 1166 1171 PF00397 0.576
DOC_WW_Pin1_4 1249 1254 PF00397 0.535
DOC_WW_Pin1_4 1259 1264 PF00397 0.479
DOC_WW_Pin1_4 1310 1315 PF00397 0.595
DOC_WW_Pin1_4 132 137 PF00397 0.434
DOC_WW_Pin1_4 1325 1330 PF00397 0.643
DOC_WW_Pin1_4 1334 1339 PF00397 0.748
DOC_WW_Pin1_4 1366 1371 PF00397 0.664
DOC_WW_Pin1_4 1372 1377 PF00397 0.710
DOC_WW_Pin1_4 16 21 PF00397 0.445
DOC_WW_Pin1_4 51 56 PF00397 0.538
DOC_WW_Pin1_4 511 516 PF00397 0.460
DOC_WW_Pin1_4 561 566 PF00397 0.477
DOC_WW_Pin1_4 914 919 PF00397 0.366
LIG_14-3-3_CanoR_1 1113 1121 PF00244 0.495
LIG_14-3-3_CanoR_1 1368 1374 PF00244 0.737
LIG_14-3-3_CanoR_1 1475 1479 PF00244 0.612
LIG_14-3-3_CanoR_1 700 705 PF00244 0.451
LIG_14-3-3_CanoR_1 746 756 PF00244 0.481
LIG_14-3-3_CanoR_1 781 791 PF00244 0.511
LIG_14-3-3_CanoR_1 888 896 PF00244 0.416
LIG_Actin_WH2_2 1049 1064 PF00022 0.516
LIG_Actin_WH2_2 1184 1200 PF00022 0.481
LIG_Actin_WH2_2 583 601 PF00022 0.248
LIG_APCC_ABBA_1 18 23 PF00400 0.459
LIG_APCC_ABBA_1 267 272 PF00400 0.421
LIG_APCC_ABBA_1 329 334 PF00400 0.538
LIG_APCC_ABBA_1 543 548 PF00400 0.434
LIG_APCC_ABBA_1 64 69 PF00400 0.538
LIG_APCC_ABBA_1 868 873 PF00400 0.396
LIG_APCC_ABBAyCdc20_2 867 873 PF00400 0.432
LIG_BRCT_BRCA1_1 144 148 PF00533 0.459
LIG_BRCT_BRCA1_1 1447 1451 PF00533 0.456
LIG_BRCT_BRCA1_1 289 293 PF00533 0.290
LIG_BRCT_BRCA1_1 733 737 PF00533 0.477
LIG_BRCT_BRCA1_1 916 920 PF00533 0.384
LIG_BRCT_BRCA1_2 733 739 PF00533 0.485
LIG_Clathr_ClatBox_1 82 86 PF01394 0.477
LIG_deltaCOP1_diTrp_1 159 169 PF00928 0.501
LIG_deltaCOP1_diTrp_1 348 357 PF00928 0.483
LIG_EH1_1 433 441 PF00400 0.459
LIG_EVH1_2 575 579 PF00568 0.516
LIG_FHA_1 1052 1058 PF00498 0.485
LIG_FHA_1 1062 1068 PF00498 0.470
LIG_FHA_1 1127 1133 PF00498 0.314
LIG_FHA_1 1140 1146 PF00498 0.427
LIG_FHA_1 1285 1291 PF00498 0.702
LIG_FHA_1 1316 1322 PF00498 0.631
LIG_FHA_1 1456 1462 PF00498 0.549
LIG_FHA_1 151 157 PF00498 0.459
LIG_FHA_1 315 321 PF00498 0.434
LIG_FHA_1 387 393 PF00498 0.458
LIG_FHA_1 399 405 PF00498 0.299
LIG_FHA_1 626 632 PF00498 0.520
LIG_FHA_1 863 869 PF00498 0.512
LIG_FHA_1 965 971 PF00498 0.518
LIG_FHA_2 1048 1054 PF00498 0.446
LIG_FHA_2 1066 1072 PF00498 0.376
LIG_FHA_2 1173 1179 PF00498 0.501
LIG_FHA_2 1209 1215 PF00498 0.632
LIG_FHA_2 1424 1430 PF00498 0.523
LIG_FHA_2 1475 1481 PF00498 0.536
LIG_FHA_2 54 60 PF00498 0.501
LIG_FHA_2 658 664 PF00498 0.458
LIG_KLC1_Yacidic_2 29 34 PF13176 0.445
LIG_LIR_Apic_2 1164 1170 PF02991 0.445
LIG_LIR_Apic_2 452 458 PF02991 0.465
LIG_LIR_Apic_2 606 611 PF02991 0.423
LIG_LIR_Apic_2 654 659 PF02991 0.434
LIG_LIR_Gen_1 145 156 PF02991 0.459
LIG_LIR_Gen_1 219 230 PF02991 0.434
LIG_LIR_Gen_1 260 270 PF02991 0.279
LIG_LIR_Gen_1 272 281 PF02991 0.285
LIG_LIR_Gen_1 29 39 PF02991 0.445
LIG_LIR_Gen_1 290 301 PF02991 0.269
LIG_LIR_Gen_1 500 508 PF02991 0.559
LIG_LIR_Gen_1 69 80 PF02991 0.459
LIG_LIR_Gen_1 958 966 PF02991 0.378
LIG_LIR_Nem_3 1093 1097 PF02991 0.455
LIG_LIR_Nem_3 12 17 PF02991 0.477
LIG_LIR_Nem_3 145 151 PF02991 0.446
LIG_LIR_Nem_3 219 225 PF02991 0.434
LIG_LIR_Nem_3 260 265 PF02991 0.281
LIG_LIR_Nem_3 272 276 PF02991 0.277
LIG_LIR_Nem_3 29 35 PF02991 0.477
LIG_LIR_Nem_3 290 296 PF02991 0.311
LIG_LIR_Nem_3 299 305 PF02991 0.509
LIG_LIR_Nem_3 365 369 PF02991 0.518
LIG_LIR_Nem_3 452 456 PF02991 0.469
LIG_LIR_Nem_3 592 598 PF02991 0.351
LIG_LIR_Nem_3 607 613 PF02991 0.368
LIG_LIR_Nem_3 632 637 PF02991 0.436
LIG_LIR_Nem_3 69 75 PF02991 0.459
LIG_LIR_Nem_3 785 790 PF02991 0.540
LIG_NRBOX 1190 1196 PF00104 0.434
LIG_NRBOX 1231 1237 PF00104 0.563
LIG_PCNA_PIPBox_1 275 284 PF02747 0.358
LIG_PCNA_PIPBox_1 428 437 PF02747 0.501
LIG_PCNA_yPIPBox_3 1000 1010 PF02747 0.443
LIG_PCNA_yPIPBox_3 1150 1161 PF02747 0.481
LIG_PCNA_yPIPBox_3 271 282 PF02747 0.488
LIG_Pex14_1 1465 1469 PF04695 0.459
LIG_Pex14_1 441 445 PF04695 0.434
LIG_Pex14_1 453 457 PF04695 0.434
LIG_Pex14_2 302 306 PF04695 0.511
LIG_Pex14_2 417 421 PF04695 0.434
LIG_Pex14_2 783 787 PF04695 0.538
LIG_PTB_Apo_2 947 954 PF02174 0.403
LIG_PTB_Phospho_1 947 953 PF10480 0.401
LIG_REV1ctd_RIR_1 4 12 PF16727 0.445
LIG_REV1ctd_RIR_1 670 680 PF16727 0.538
LIG_SH2_CRK 1167 1171 PF00017 0.481
LIG_SH2_CRK 447 451 PF00017 0.454
LIG_SH2_CRK 608 612 PF00017 0.394
LIG_SH2_CRK 941 945 PF00017 0.314
LIG_SH2_GRB2like 1455 1458 PF00017 0.430
LIG_SH2_NCK_1 1167 1171 PF00017 0.445
LIG_SH2_NCK_1 556 560 PF00017 0.459
LIG_SH2_PTP2 827 830 PF00017 0.530
LIG_SH2_SRC 1019 1022 PF00017 0.417
LIG_SH2_SRC 32 35 PF00017 0.481
LIG_SH2_SRC 435 438 PF00017 0.434
LIG_SH2_STAP1 106 110 PF00017 0.434
LIG_SH2_STAP1 941 945 PF00017 0.314
LIG_SH2_STAT3 445 448 PF00017 0.445
LIG_SH2_STAT3 790 793 PF00017 0.450
LIG_SH2_STAT5 1009 1012 PF00017 0.289
LIG_SH2_STAT5 1019 1022 PF00017 0.368
LIG_SH2_STAT5 1108 1111 PF00017 0.363
LIG_SH2_STAT5 1131 1134 PF00017 0.545
LIG_SH2_STAT5 1455 1458 PF00017 0.430
LIG_SH2_STAT5 150 153 PF00017 0.434
LIG_SH2_STAT5 273 276 PF00017 0.278
LIG_SH2_STAT5 281 284 PF00017 0.301
LIG_SH2_STAT5 32 35 PF00017 0.445
LIG_SH2_STAT5 332 335 PF00017 0.439
LIG_SH2_STAT5 342 345 PF00017 0.426
LIG_SH2_STAT5 435 438 PF00017 0.434
LIG_SH2_STAT5 501 504 PF00017 0.538
LIG_SH2_STAT5 522 525 PF00017 0.477
LIG_SH2_STAT5 67 70 PF00017 0.445
LIG_SH2_STAT5 764 767 PF00017 0.443
LIG_SH2_STAT5 80 83 PF00017 0.445
LIG_SH2_STAT5 827 830 PF00017 0.416
LIG_SH2_STAT5 953 956 PF00017 0.475
LIG_SH2_STAT5 997 1000 PF00017 0.361
LIG_SH3_3 1117 1123 PF00018 0.541
LIG_SH3_3 1199 1205 PF00018 0.447
LIG_SH3_3 1248 1254 PF00018 0.628
LIG_SH3_3 1287 1293 PF00018 0.652
LIG_SH3_3 133 139 PF00018 0.538
LIG_SH3_3 1370 1376 PF00018 0.661
LIG_SH3_3 1408 1414 PF00018 0.770
LIG_SH3_3 310 316 PF00018 0.434
LIG_SH3_3 466 472 PF00018 0.462
LIG_SH3_3 482 488 PF00018 0.479
LIG_SH3_3 492 498 PF00018 0.473
LIG_SH3_3 512 518 PF00018 0.348
LIG_SH3_3 539 545 PF00018 0.434
LIG_SH3_3 569 575 PF00018 0.514
LIG_SH3_3 688 694 PF00018 0.434
LIG_SH3_3 912 918 PF00018 0.486
LIG_SUMO_SIM_anti_2 1192 1201 PF11976 0.546
LIG_SUMO_SIM_anti_2 539 545 PF11976 0.434
LIG_SUMO_SIM_anti_2 757 763 PF11976 0.460
LIG_SUMO_SIM_anti_2 899 904 PF11976 0.464
LIG_SUMO_SIM_par_1 1192 1201 PF11976 0.601
LIG_SUMO_SIM_par_1 211 217 PF11976 0.435
LIG_SUMO_SIM_par_1 81 86 PF11976 0.477
LIG_TRAF2_1 1069 1072 PF00917 0.568
LIG_TRAF2_1 111 114 PF00917 0.434
LIG_TYR_ITIM 939 944 PF00017 0.312
LIG_UBA3_1 1194 1198 PF00899 0.456
LIG_UBA3_1 64 70 PF00899 0.284
LIG_UBA3_1 665 674 PF00899 0.328
LIG_UBA3_1 71 79 PF00899 0.284
LIG_UBA3_1 959 965 PF00899 0.504
LIG_WRC_WIRS_1 1052 1057 PF05994 0.459
LIG_WRC_WIRS_1 1466 1471 PF05994 0.456
MOD_CDK_SPxK_1 16 22 PF00069 0.284
MOD_CDK_SPxxK_3 1325 1332 PF00069 0.570
MOD_CDK_SPxxK_3 51 58 PF00069 0.414
MOD_CDK_SPxxK_3 514 521 PF00069 0.269
MOD_CK1_1 1246 1252 PF00069 0.607
MOD_CK1_1 1275 1281 PF00069 0.606
MOD_CK1_1 1322 1328 PF00069 0.686
MOD_CK1_1 1337 1343 PF00069 0.576
MOD_CK1_1 1350 1356 PF00069 0.627
MOD_CK1_1 1366 1372 PF00069 0.688
MOD_CK1_1 1375 1381 PF00069 0.637
MOD_CK1_1 1395 1401 PF00069 0.602
MOD_CK1_1 1420 1426 PF00069 0.691
MOD_CK1_1 16 22 PF00069 0.328
MOD_CK1_1 287 293 PF00069 0.357
MOD_CK1_1 500 506 PF00069 0.286
MOD_CK1_1 514 520 PF00069 0.376
MOD_CK1_1 834 840 PF00069 0.562
MOD_CK1_1 844 850 PF00069 0.444
MOD_CK1_1 909 915 PF00069 0.361
MOD_CK2_1 1047 1053 PF00069 0.360
MOD_CK2_1 1065 1071 PF00069 0.430
MOD_CK2_1 1090 1096 PF00069 0.440
MOD_CK2_1 1156 1162 PF00069 0.328
MOD_CK2_1 1474 1480 PF00069 0.523
MOD_CK2_1 232 238 PF00069 0.520
MOD_CK2_1 399 405 PF00069 0.331
MOD_CK2_1 51 57 PF00069 0.320
MOD_CK2_1 719 725 PF00069 0.442
MOD_Cter_Amidation 1308 1311 PF01082 0.694
MOD_GlcNHglycan 1058 1061 PF01048 0.474
MOD_GlcNHglycan 1158 1161 PF01048 0.408
MOD_GlcNHglycan 1191 1194 PF01048 0.361
MOD_GlcNHglycan 1225 1228 PF01048 0.487
MOD_GlcNHglycan 1244 1248 PF01048 0.411
MOD_GlcNHglycan 1274 1277 PF01048 0.647
MOD_GlcNHglycan 1294 1297 PF01048 0.658
MOD_GlcNHglycan 1302 1305 PF01048 0.638
MOD_GlcNHglycan 1315 1318 PF01048 0.573
MOD_GlcNHglycan 1349 1352 PF01048 0.576
MOD_GlcNHglycan 1382 1385 PF01048 0.642
MOD_GlcNHglycan 1394 1397 PF01048 0.488
MOD_GlcNHglycan 1447 1450 PF01048 0.481
MOD_GlcNHglycan 169 172 PF01048 0.269
MOD_GlcNHglycan 352 355 PF01048 0.202
MOD_GlcNHglycan 621 624 PF01048 0.368
MOD_GlcNHglycan 721 724 PF01048 0.419
MOD_GlcNHglycan 732 736 PF01048 0.420
MOD_GlcNHglycan 818 821 PF01048 0.467
MOD_GlcNHglycan 992 995 PF01048 0.478
MOD_GSK3_1 1047 1054 PF00069 0.443
MOD_GSK3_1 1061 1068 PF00069 0.498
MOD_GSK3_1 1243 1250 PF00069 0.612
MOD_GSK3_1 1275 1282 PF00069 0.657
MOD_GSK3_1 128 135 PF00069 0.269
MOD_GSK3_1 1292 1299 PF00069 0.487
MOD_GSK3_1 1300 1307 PF00069 0.607
MOD_GSK3_1 1309 1316 PF00069 0.640
MOD_GSK3_1 1319 1326 PF00069 0.552
MOD_GSK3_1 1337 1344 PF00069 0.745
MOD_GSK3_1 1346 1353 PF00069 0.589
MOD_GSK3_1 1362 1369 PF00069 0.530
MOD_GSK3_1 1388 1395 PF00069 0.639
MOD_GSK3_1 1423 1430 PF00069 0.705
MOD_GSK3_1 1453 1460 PF00069 0.464
MOD_GSK3_1 1461 1468 PF00069 0.459
MOD_GSK3_1 150 157 PF00069 0.463
MOD_GSK3_1 632 639 PF00069 0.337
MOD_GSK3_1 657 664 PF00069 0.314
MOD_GSK3_1 707 714 PF00069 0.364
MOD_GSK3_1 717 724 PF00069 0.303
MOD_GSK3_1 812 819 PF00069 0.496
MOD_GSK3_1 905 912 PF00069 0.337
MOD_GSK3_1 992 999 PF00069 0.402
MOD_N-GLC_1 1090 1095 PF02516 0.413
MOD_N-GLC_1 1223 1228 PF02516 0.562
MOD_N-GLC_1 1420 1425 PF02516 0.689
MOD_N-GLC_1 197 202 PF02516 0.269
MOD_N-GLC_1 40 45 PF02516 0.284
MOD_N-GLC_1 476 481 PF02516 0.381
MOD_N-GLC_1 561 566 PF02516 0.334
MOD_N-GLC_1 661 666 PF02516 0.363
MOD_N-GLC_1 888 893 PF02516 0.461
MOD_N-GLC_1 984 989 PF02516 0.554
MOD_NEK2_1 1056 1061 PF00069 0.468
MOD_NEK2_1 1082 1087 PF00069 0.505
MOD_NEK2_1 1156 1161 PF00069 0.303
MOD_NEK2_1 1181 1186 PF00069 0.396
MOD_NEK2_1 1321 1326 PF00069 0.600
MOD_NEK2_1 1341 1346 PF00069 0.680
MOD_NEK2_1 1461 1466 PF00069 0.540
MOD_NEK2_1 594 599 PF00069 0.476
MOD_NEK2_1 747 752 PF00069 0.374
MOD_NEK2_1 771 776 PF00069 0.290
MOD_NEK2_1 783 788 PF00069 0.284
MOD_NEK2_1 929 934 PF00069 0.493
MOD_NEK2_2 150 155 PF00069 0.284
MOD_NEK2_2 651 656 PF00069 0.320
MOD_PIKK_1 1146 1152 PF00454 0.290
MOD_PIKK_1 1208 1214 PF00454 0.636
MOD_PIKK_1 1363 1369 PF00454 0.605
MOD_PIKK_1 1415 1421 PF00454 0.746
MOD_PIKK_1 747 753 PF00454 0.334
MOD_PIKK_1 834 840 PF00454 0.449
MOD_PIKK_1 855 861 PF00454 0.512
MOD_PK_1 13 19 PF00069 0.328
MOD_PK_1 674 680 PF00069 0.421
MOD_PKA_1 1433 1439 PF00069 0.544
MOD_PKA_1 604 610 PF00069 0.470
MOD_PKA_2 1112 1118 PF00069 0.441
MOD_PKA_2 1139 1145 PF00069 0.358
MOD_PKA_2 1331 1337 PF00069 0.561
MOD_PKA_2 142 148 PF00069 0.284
MOD_PKA_2 1433 1439 PF00069 0.738
MOD_PKA_2 1474 1480 PF00069 0.560
MOD_PKA_2 604 610 PF00069 0.474
MOD_PKA_2 657 663 PF00069 0.328
MOD_PKB_1 698 706 PF00069 0.305
MOD_Plk_1 1082 1088 PF00069 0.505
MOD_Plk_1 1090 1096 PF00069 0.477
MOD_Plk_1 1126 1132 PF00069 0.328
MOD_Plk_1 392 398 PF00069 0.375
MOD_Plk_1 476 482 PF00069 0.354
MOD_Plk_1 548 554 PF00069 0.363
MOD_Plk_1 661 667 PF00069 0.404
MOD_Plk_1 888 894 PF00069 0.435
MOD_Plk_2-3 1047 1053 PF00069 0.388
MOD_Plk_2-3 422 428 PF00069 0.312
MOD_Plk_2-3 964 970 PF00069 0.511
MOD_Plk_4 1051 1057 PF00069 0.458
MOD_Plk_4 1126 1132 PF00069 0.290
MOD_Plk_4 1149 1155 PF00069 0.269
MOD_Plk_4 1285 1291 PF00069 0.692
MOD_Plk_4 13 19 PF00069 0.284
MOD_Plk_4 1457 1463 PF00069 0.512
MOD_Plk_4 277 283 PF00069 0.228
MOD_Plk_4 393 399 PF00069 0.483
MOD_Plk_4 497 503 PF00069 0.433
MOD_Plk_4 651 657 PF00069 0.261
MOD_Plk_4 661 667 PF00069 0.253
MOD_Plk_4 680 686 PF00069 0.247
MOD_Plk_4 844 850 PF00069 0.555
MOD_Plk_4 910 916 PF00069 0.458
MOD_Plk_4 992 998 PF00069 0.408
MOD_ProDKin_1 1061 1067 PF00069 0.495
MOD_ProDKin_1 1166 1172 PF00069 0.467
MOD_ProDKin_1 1249 1255 PF00069 0.533
MOD_ProDKin_1 1259 1265 PF00069 0.480
MOD_ProDKin_1 1310 1316 PF00069 0.593
MOD_ProDKin_1 132 138 PF00069 0.269
MOD_ProDKin_1 1325 1331 PF00069 0.643
MOD_ProDKin_1 1334 1340 PF00069 0.750
MOD_ProDKin_1 1366 1372 PF00069 0.667
MOD_ProDKin_1 16 22 PF00069 0.284
MOD_ProDKin_1 51 57 PF00069 0.414
MOD_ProDKin_1 511 517 PF00069 0.305
MOD_ProDKin_1 561 567 PF00069 0.328
MOD_ProDKin_1 914 920 PF00069 0.362
MOD_SUMO_rev_2 120 128 PF00179 0.303
MOD_SUMO_rev_2 173 183 PF00179 0.272
MOD_SUMO_rev_2 240 250 PF00179 0.571
MOD_SUMO_rev_2 272 280 PF00179 0.217
TRG_AP2beta_CARGO_1 632 641 PF09066 0.372
TRG_DiLeu_BaEn_1 1231 1236 PF01217 0.562
TRG_DiLeu_BaEn_1 246 251 PF01217 0.554
TRG_DiLeu_BaEn_1 539 544 PF01217 0.269
TRG_DiLeu_BaEn_2 1030 1036 PF01217 0.472
TRG_DiLeu_BaEn_2 1050 1056 PF01217 0.241
TRG_DiLeu_BaEn_2 146 152 PF01217 0.414
TRG_DiLeu_BaEn_2 732 738 PF01217 0.367
TRG_DiLeu_BaLyEn_6 1012 1017 PF01217 0.388
TRG_DiLeu_BaLyEn_6 1152 1157 PF01217 0.303
TRG_DiLeu_BaLyEn_6 507 512 PF01217 0.280
TRG_ENDOCYTIC_2 106 109 PF00928 0.269
TRG_ENDOCYTIC_2 1108 1111 PF00928 0.370
TRG_ENDOCYTIC_2 273 276 PF00928 0.278
TRG_ENDOCYTIC_2 32 35 PF00928 0.351
TRG_ENDOCYTIC_2 447 450 PF00928 0.372
TRG_ENDOCYTIC_2 461 464 PF00928 0.196
TRG_ENDOCYTIC_2 501 504 PF00928 0.322
TRG_ENDOCYTIC_2 508 511 PF00928 0.310
TRG_ENDOCYTIC_2 556 559 PF00928 0.269
TRG_ENDOCYTIC_2 80 83 PF00928 0.363
TRG_ENDOCYTIC_2 941 944 PF00928 0.313
TRG_ER_diArg_1 1291 1294 PF00400 0.615
TRG_ER_diArg_1 186 189 PF00400 0.269
TRG_ER_diArg_1 369 372 PF00400 0.347
TRG_ER_diArg_1 383 386 PF00400 0.284
TRG_ER_diArg_1 428 430 PF00400 0.325
TRG_ER_diArg_1 603 605 PF00400 0.378
TRG_ER_diArg_1 698 701 PF00400 0.288
TRG_ER_diArg_1 98 101 PF00400 0.269
TRG_NES_CRM1_1 1047 1058 PF08389 0.424
TRG_NES_CRM1_1 592 606 PF08389 0.458
TRG_NLS_MonoExtC_3 1010 1015 PF00514 0.437
TRG_NLS_MonoExtN_4 694 701 PF00514 0.383
TRG_Pf-PMV_PEXEL_1 1014 1018 PF00026 0.445
TRG_Pf-PMV_PEXEL_1 1476 1480 PF00026 0.604
TRG_Pf-PMV_PEXEL_1 295 299 PF00026 0.284
TRG_Pf-PMV_PEXEL_1 429 433 PF00026 0.383
TRG_Pf-PMV_PEXEL_1 521 525 PF00026 0.414
TRG_Pf-PMV_PEXEL_1 641 645 PF00026 0.334

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6H6 Leptomonas seymouri 74% 99%
A0A0S4IZP1 Bodo saltans 54% 100%
A0A1X0NJD0 Trypanosomatidae 59% 96%
A0A3R7KY45 Trypanosoma rangeli 51% 100%
A0A3S5H5P0 Leishmania donovani 96% 99%
A4H4J2 Leishmania braziliensis 87% 98%
A4HSR7 Leishmania infantum 96% 99%
C9ZTC0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 100%
E9AKQ4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 98%
Q8IZH2 Homo sapiens 30% 87%
V5D681 Trypanosoma cruzi 53% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS