MYND finger domain-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MYND finger domain-like protein

Species:

Leishmania major

UniProt:

Q4QJ49_LEIMA

TriTrypDb:

LmjF.06.0300 , LMJLV39_060008200 , LMJSD75_060008200

Length:

167

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJ49

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ49

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	143	147	PF00082	0.319
DOC_MAPK_gen_1	126	136	PF00069	0.300
DOC_USP7_UBL2_3	154	158	PF12436	0.369
DOC_WW_Pin1_4	114	119	PF00397	0.502
LIG_14-3-3_CanoR_1	129	135	PF00244	0.301
LIG_Clathr_ClatBox_1	103	107	PF01394	0.500
LIG_FHA_1	131	137	PF00498	0.339
LIG_FHA_1	26	32	PF00498	0.474
LIG_FHA_1	62	68	PF00498	0.392
LIG_FHA_2	41	47	PF00498	0.452
LIG_Pex14_2	73	77	PF04695	0.499
LIG_SH2_STAP1	29	33	PF00017	0.482
LIG_SH2_STAT5	102	105	PF00017	0.513
LIG_SH2_STAT5	147	150	PF00017	0.297
LIG_SH3_3	160	166	PF00018	0.357
LIG_TRAF2_1	36	39	PF00917	0.461
LIG_WW_3	77	81	PF00397	0.398
MOD_CK2_1	40	46	PF00069	0.448
MOD_GlcNHglycan	90	93	PF01048	0.446
MOD_N-GLC_2	119	121	PF02516	0.387
MOD_NEK2_1	15	20	PF00069	0.466
MOD_NEK2_1	73	78	PF00069	0.527
MOD_PIKK_1	22	28	PF00454	0.502
MOD_PK_1	146	152	PF00069	0.369
MOD_PKA_2	137	143	PF00069	0.357
MOD_Plk_4	40	46	PF00069	0.430
MOD_Plk_4	67	73	PF00069	0.483
MOD_ProDKin_1	114	120	PF00069	0.490
MOD_SUMO_rev_2	151	159	PF00179	0.403
MOD_SUMO_rev_2	51	61	PF00179	0.295
TRG_DiLeu_BaLyEn_6	62	67	PF01217	0.412
TRG_ENDOCYTIC_2	147	150	PF00928	0.369
TRG_Pf-PMV_PEXEL_1	101	105	PF00026	0.439

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL36	Leptomonas seymouri	82%	94%
A0A0S4JPC0	Bodo saltans	40%	100%
A0A3S5H5P3	Leishmania donovani	96%	99%
A4H4J6	Leishmania braziliensis	81%	93%
A4HSS1	Leishmania infantum	96%	99%
E9AKQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	99%