C2H2-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QJ38_LEIMA

TriTrypDb:

LmjF.06.0412 , LMJLV39_060009700 , LMJSD75_060009700

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJ38

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ38

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	104	108	PF00656	0.633
CLV_NRD_NRD_1	156	158	PF00675	0.670
CLV_NRD_NRD_1	29	31	PF00675	0.476
CLV_NRD_NRD_1	61	63	PF00675	0.637
CLV_NRD_NRD_1	94	96	PF00675	0.668
CLV_PCSK_FUR_1	154	158	PF00082	0.495
CLV_PCSK_KEX2_1	149	151	PF00082	0.496
CLV_PCSK_KEX2_1	156	158	PF00082	0.593
CLV_PCSK_KEX2_1	29	31	PF00082	0.476
CLV_PCSK_KEX2_1	41	43	PF00082	0.494
CLV_PCSK_PC1ET2_1	149	151	PF00082	0.597
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.494
CLV_PCSK_SKI1_1	180	184	PF00082	0.447
CLV_PCSK_SKI1_1	22	26	PF00082	0.445
CLV_PCSK_SKI1_1	57	61	PF00082	0.509
DEG_SPOP_SBC_1	70	74	PF00917	0.744
DEG_SPOP_SBC_1	85	89	PF00917	0.455
DOC_MAPK_gen_1	179	186	PF00069	0.455
DOC_MAPK_MEF2A_6	131	140	PF00069	0.612
DOC_USP7_MATH_1	112	116	PF00917	0.734
DOC_USP7_MATH_1	120	124	PF00917	0.655
DOC_USP7_MATH_1	125	129	PF00917	0.565
DOC_USP7_MATH_1	70	74	PF00917	0.621
DOC_USP7_UBL2_3	145	149	PF12436	0.536
LIG_APCC_ABBA_1	18	23	PF00400	0.442
LIG_BIR_II_1	1	5	PF00653	0.577
LIG_BIR_III_4	107	111	PF00653	0.643
LIG_FHA_1	3	9	PF00498	0.534
LIG_FHA_1	54	60	PF00498	0.502
LIG_FHA_1	85	91	PF00498	0.737
LIG_FHA_2	89	95	PF00498	0.673
LIG_SH2_STAT5	10	13	PF00017	0.437
LIG_SH3_3	116	122	PF00018	0.598
LIG_SUMO_SIM_par_1	136	141	PF11976	0.605
MOD_CK1_1	173	179	PF00069	0.528
MOD_CK1_1	2	8	PF00069	0.547
MOD_CK1_1	74	80	PF00069	0.678
MOD_CK2_1	88	94	PF00069	0.670
MOD_Cter_Amidation	177	180	PF01082	0.483
MOD_GlcNHglycan	115	118	PF01048	0.774
MOD_GlcNHglycan	123	126	PF01048	0.734
MOD_GSK3_1	121	128	PF00069	0.759
MOD_GSK3_1	136	143	PF00069	0.434
MOD_GSK3_1	169	176	PF00069	0.465
MOD_GSK3_1	70	77	PF00069	0.627
MOD_GSK3_1	84	91	PF00069	0.670
MOD_NEK2_1	35	40	PF00069	0.649
MOD_NEK2_2	126	131	PF00069	0.674
MOD_PIKK_1	35	41	PF00454	0.644
MOD_PIKK_1	71	77	PF00454	0.681
MOD_PKA_2	53	59	PF00069	0.663
MOD_Plk_4	170	176	PF00069	0.588
MOD_SUMO_rev_2	172	181	PF00179	0.459
TRG_DiLeu_BaEn_1	55	60	PF01217	0.499
TRG_ER_diArg_1	154	157	PF00400	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II80	Leptomonas seymouri	50%	92%
A0A3S5H5Q2	Leishmania donovani	96%	100%
A4H4K6	Leishmania braziliensis	80%	100%
A4HST2	Leishmania infantum	96%	100%
E9AKR9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%