Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QJ36_LEIMA

TriTrypDb:

LmjF.06.0420 , LMJLV39_060009900 , LMJSD75_060009900

Length:

573

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QJ36

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ36

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	382	384	PF00675	0.823
CLV_NRD_NRD_1	426	428	PF00675	0.741
CLV_NRD_NRD_1	435	437	PF00675	0.669
CLV_NRD_NRD_1	510	512	PF00675	0.825
CLV_NRD_NRD_1	515	517	PF00675	0.797
CLV_NRD_NRD_1	548	550	PF00675	0.805
CLV_NRD_NRD_1	70	72	PF00675	0.667
CLV_NRD_NRD_1	93	95	PF00675	0.652
CLV_PCSK_FUR_1	380	384	PF00082	0.761
CLV_PCSK_KEX2_1	269	271	PF00082	0.794
CLV_PCSK_KEX2_1	382	384	PF00082	0.823
CLV_PCSK_KEX2_1	426	428	PF00082	0.834
CLV_PCSK_KEX2_1	435	437	PF00082	0.669
CLV_PCSK_KEX2_1	514	516	PF00082	0.867
CLV_PCSK_KEX2_1	70	72	PF00082	0.667
CLV_PCSK_PC1ET2_1	269	271	PF00082	0.835
CLV_PCSK_PC1ET2_1	514	516	PF00082	0.867
CLV_PCSK_PC7_1	511	517	PF00082	0.857
CLV_PCSK_SKI1_1	133	137	PF00082	0.518
CLV_PCSK_SKI1_1	270	274	PF00082	0.775
CLV_PCSK_SKI1_1	40	44	PF00082	0.714
CLV_PCSK_SKI1_1	533	537	PF00082	0.677
DEG_APCC_DBOX_1	269	277	PF00400	0.773
DOC_ANK_TNKS_1	366	373	PF00023	0.586
DOC_CKS1_1	326	331	PF01111	0.713
DOC_CYCLIN_RxL_1	494	504	PF00134	0.581
DOC_MAPK_gen_1	269	276	PF00069	0.835
DOC_MAPK_gen_1	352	361	PF00069	0.838
DOC_USP7_MATH_1	166	170	PF00917	0.787
DOC_USP7_MATH_1	176	180	PF00917	0.584
DOC_USP7_MATH_1	182	186	PF00917	0.631
DOC_USP7_MATH_1	189	193	PF00917	0.629
DOC_USP7_MATH_1	226	230	PF00917	0.743
DOC_USP7_MATH_1	268	272	PF00917	0.829
DOC_USP7_MATH_1	301	305	PF00917	0.736
DOC_USP7_MATH_1	351	355	PF00917	0.727
DOC_USP7_MATH_1	374	378	PF00917	0.589
DOC_USP7_MATH_1	420	424	PF00917	0.647
DOC_USP7_MATH_1	463	467	PF00917	0.698
DOC_USP7_MATH_1	49	53	PF00917	0.747
DOC_USP7_MATH_2	57	63	PF00917	0.665
DOC_WW_Pin1_4	200	205	PF00397	0.794
DOC_WW_Pin1_4	264	269	PF00397	0.647
DOC_WW_Pin1_4	284	289	PF00397	0.716
DOC_WW_Pin1_4	325	330	PF00397	0.712
DOC_WW_Pin1_4	345	350	PF00397	0.710
DOC_WW_Pin1_4	409	414	PF00397	0.593
DOC_WW_Pin1_4	45	50	PF00397	0.653
DOC_WW_Pin1_4	53	58	PF00397	0.635
DOC_WW_Pin1_4	559	564	PF00397	0.639
LIG_14-3-3_CanoR_1	280	288	PF00244	0.855
LIG_14-3-3_CanoR_1	395	403	PF00244	0.813
LIG_14-3-3_CanoR_1	50	54	PF00244	0.741
LIG_14-3-3_CanoR_1	515	519	PF00244	0.810
LIG_14-3-3_CanoR_1	559	563	PF00244	0.754
LIG_14-3-3_CanoR_1	568	573	PF00244	0.606
LIG_APCC_ABBAyCdc20_2	290	296	PF00400	0.799
LIG_BIR_III_4	337	341	PF00653	0.742
LIG_BRCT_BRCA1_1	357	361	PF00533	0.607
LIG_deltaCOP1_diTrp_1	101	109	PF00928	0.646
LIG_FHA_1	109	115	PF00498	0.576
LIG_FHA_1	13	19	PF00498	0.755
LIG_FHA_1	326	332	PF00498	0.803
LIG_FHA_1	366	372	PF00498	0.653
LIG_FHA_1	49	55	PF00498	0.708
LIG_FHA_1	530	536	PF00498	0.614
LIG_FHA_1	58	64	PF00498	0.642
LIG_FHA_2	154	160	PF00498	0.691
LIG_FHA_2	501	507	PF00498	0.756
LIG_LIR_Apic_2	333	339	PF02991	0.607
LIG_LIR_Gen_1	496	502	PF02991	0.807
LIG_LIR_Nem_3	496	501	PF02991	0.804
LIG_SH2_CRK	336	340	PF00017	0.613
LIG_SH2_CRK	439	443	PF00017	0.754
LIG_SH2_NCK_1	336	340	PF00017	0.613
LIG_SH2_SRC	460	463	PF00017	0.816
LIG_SH2_STAP1	110	114	PF00017	0.600
LIG_SH2_STAT3	110	113	PF00017	0.636
LIG_SH2_STAT5	110	113	PF00017	0.636
LIG_SH2_STAT5	155	158	PF00017	0.688
LIG_SH2_STAT5	460	463	PF00017	0.816
LIG_SH2_STAT5	498	501	PF00017	0.808
LIG_SH2_STAT5	53	56	PF00017	0.818
LIG_SH3_1	336	342	PF00018	0.612
LIG_SH3_3	13	19	PF00018	0.748
LIG_SH3_3	289	295	PF00018	0.838
LIG_SH3_3	323	329	PF00018	0.721
LIG_SH3_3	336	342	PF00018	0.714
LIG_SH3_3	480	486	PF00018	0.671
LIG_Sin3_3	399	406	PF02671	0.760
MOD_CDC14_SPxK_1	267	270	PF00782	0.598
MOD_CDC14_SPxK_1	287	290	PF00782	0.702
MOD_CDC14_SPxK_1	412	415	PF00782	0.604
MOD_CDK_SPK_2	264	269	PF00069	0.604
MOD_CDK_SPK_2	45	50	PF00069	0.804
MOD_CDK_SPxK_1	200	206	PF00069	0.751
MOD_CDK_SPxK_1	264	270	PF00069	0.648
MOD_CDK_SPxK_1	284	290	PF00069	0.697
MOD_CDK_SPxK_1	409	415	PF00069	0.597
MOD_CDK_SPxxK_3	345	352	PF00069	0.785
MOD_CK1_1	169	175	PF00069	0.785
MOD_CK1_1	217	223	PF00069	0.805
MOD_CK1_1	284	290	PF00069	0.800
MOD_CK1_1	31	37	PF00069	0.765
MOD_CK1_1	315	321	PF00069	0.740
MOD_CK1_1	360	366	PF00069	0.819
MOD_CK1_1	48	54	PF00069	0.756
MOD_CK1_1	517	523	PF00069	0.770
MOD_CK1_1	558	564	PF00069	0.808
MOD_CK1_1	62	68	PF00069	0.547
MOD_CK2_1	153	159	PF00069	0.718
MOD_CK2_1	212	218	PF00069	0.790
MOD_CK2_1	53	59	PF00069	0.806
MOD_CK2_1	74	80	PF00069	0.471
MOD_Cter_Amidation	424	427	PF01082	0.799
MOD_DYRK1A_RPxSP_1	264	268	PF00069	0.582
MOD_GlcNHglycan	171	174	PF01048	0.774
MOD_GlcNHglycan	178	181	PF01048	0.690
MOD_GlcNHglycan	184	187	PF01048	0.649
MOD_GlcNHglycan	191	194	PF01048	0.549
MOD_GlcNHglycan	200	203	PF01048	0.568
MOD_GlcNHglycan	214	217	PF01048	0.793
MOD_GlcNHglycan	23	26	PF01048	0.708
MOD_GlcNHglycan	253	256	PF01048	0.709
MOD_GlcNHglycan	259	262	PF01048	0.615
MOD_GlcNHglycan	270	273	PF01048	0.546
MOD_GlcNHglycan	283	286	PF01048	0.618
MOD_GlcNHglycan	31	34	PF01048	0.792
MOD_GlcNHglycan	345	348	PF01048	0.683
MOD_GlcNHglycan	35	38	PF01048	0.529
MOD_GlcNHglycan	376	379	PF01048	0.657
MOD_GlcNHglycan	392	395	PF01048	0.709
MOD_GlcNHglycan	397	400	PF01048	0.657
MOD_GlcNHglycan	416	419	PF01048	0.562
MOD_GlcNHglycan	422	425	PF01048	0.826
MOD_GlcNHglycan	446	449	PF01048	0.682
MOD_GlcNHglycan	478	481	PF01048	0.682
MOD_GlcNHglycan	503	506	PF01048	0.657
MOD_GlcNHglycan	520	523	PF01048	0.686
MOD_GlcNHglycan	537	540	PF01048	0.615
MOD_GlcNHglycan	64	67	PF01048	0.672
MOD_GSK3_1	137	144	PF00069	0.703
MOD_GSK3_1	167	174	PF00069	0.744
MOD_GSK3_1	264	271	PF00069	0.605
MOD_GSK3_1	29	36	PF00069	0.751
MOD_GSK3_1	351	358	PF00069	0.807
MOD_GSK3_1	361	368	PF00069	0.613
MOD_GSK3_1	438	445	PF00069	0.647
MOD_GSK3_1	446	453	PF00069	0.647
MOD_GSK3_1	45	52	PF00069	0.647
MOD_GSK3_1	514	521	PF00069	0.854
MOD_GSK3_1	53	60	PF00069	0.671
MOD_GSK3_1	555	562	PF00069	0.813
MOD_N-GLC_1	29	34	PF02516	0.783
MOD_N-GLC_1	450	455	PF02516	0.773
MOD_N-GLC_1	463	468	PF02516	0.643
MOD_N-GLC_1	507	512	PF02516	0.767
MOD_NEK2_1	128	133	PF00069	0.599
MOD_NEK2_1	136	141	PF00069	0.562
MOD_NEK2_1	281	286	PF00069	0.790
MOD_NEK2_1	29	34	PF00069	0.705
MOD_NEK2_1	361	366	PF00069	0.654
MOD_NEK2_1	402	407	PF00069	0.608
MOD_NEK2_1	442	447	PF00069	0.798
MOD_NEK2_1	488	493	PF00069	0.701
MOD_NEK2_1	518	523	PF00069	0.831
MOD_PIKK_1	365	371	PF00454	0.635
MOD_PIKK_1	543	549	PF00454	0.749
MOD_PK_1	355	361	PF00069	0.732
MOD_PKA_1	514	520	PF00069	0.861
MOD_PKA_1	549	555	PF00069	0.749
MOD_PKA_2	279	285	PF00069	0.849
MOD_PKA_2	315	321	PF00069	0.771
MOD_PKA_2	351	357	PF00069	0.775
MOD_PKA_2	414	420	PF00069	0.624
MOD_PKA_2	425	431	PF00069	0.665
MOD_PKA_2	49	55	PF00069	0.779
MOD_PKA_2	514	520	PF00069	0.861
MOD_PKA_2	558	564	PF00069	0.766
MOD_Plk_1	128	134	PF00069	0.604
MOD_Plk_1	450	456	PF00069	0.639
MOD_Plk_1	58	64	PF00069	0.785
MOD_Plk_2-3	74	80	PF00069	0.505
MOD_Plk_4	49	55	PF00069	0.790
MOD_Plk_4	74	80	PF00069	0.505
MOD_ProDKin_1	200	206	PF00069	0.796
MOD_ProDKin_1	264	270	PF00069	0.648
MOD_ProDKin_1	284	290	PF00069	0.719
MOD_ProDKin_1	325	331	PF00069	0.714
MOD_ProDKin_1	345	351	PF00069	0.703
MOD_ProDKin_1	409	415	PF00069	0.597
MOD_ProDKin_1	45	51	PF00069	0.654
MOD_ProDKin_1	53	59	PF00069	0.633
MOD_ProDKin_1	559	565	PF00069	0.637
TRG_ENDOCYTIC_2	439	442	PF00928	0.822
TRG_ENDOCYTIC_2	498	501	PF00928	0.808
TRG_ER_diArg_1	205	208	PF00400	0.793
TRG_ER_diArg_1	379	382	PF00400	0.815
TRG_NLS_MonoCore_2	510	515	PF00514	0.790
TRG_NLS_MonoExtC_3	510	515	PF00514	0.790
TRG_NLS_MonoExtN_4	511	518	PF00514	0.857
TRG_Pf-PMV_PEXEL_1	117	122	PF00026	0.603
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	94	98	PF00026	0.643

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WPD6	Leishmania donovani	87%	100%
A4HST4	Leishmania infantum	87%	100%
E9AI22	Leishmania braziliensis	59%	100%
E9AKS1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	100%