NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QJ10_LEIMA

TriTrypDb:

LmjF.06.0680 , LMJLV39_060012600 , LMJSD75_060012500

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005743	mitochondrial inner membrane	5	8
GO:0005758	mitochondrial intermembrane space	6	8
GO:0016020	membrane	2	8
GO:0019866	organelle inner membrane	4	8
GO:0031090	organelle membrane	3	8
GO:0031966	mitochondrial membrane	4	8
GO:0031970	organelle envelope lumen	5	8
GO:0031974	membrane-enclosed lumen	2	8
GO:0043233	organelle lumen	3	8
GO:0070013	intracellular organelle lumen	4	8
GO:0070469	respirasome	2	8
GO:0110165	cellular anatomical entity	1	9
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

Q4QJ10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QJ10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	21	25	PF00656	0.620
CLV_C14_Caspase3-7	38	42	PF00656	0.561
CLV_NRD_NRD_1	144	146	PF00675	0.438
CLV_NRD_NRD_1	65	67	PF00675	0.509
CLV_PCSK_KEX2_1	144	146	PF00082	0.440
CLV_PCSK_KEX2_1	65	67	PF00082	0.530
CLV_PCSK_PC1ET2_1	65	67	PF00082	0.530
DEG_SPOP_SBC_1	17	21	PF00917	0.530
DEG_SPOP_SBC_1	9	13	PF00917	0.617
DOC_CKS1_1	56	61	PF01111	0.565
DOC_MAPK_gen_1	203	210	PF00069	0.503
DOC_PP2B_LxvP_1	124	127	PF13499	0.579
DOC_USP7_MATH_1	128	132	PF00917	0.357
DOC_USP7_MATH_1	3	7	PF00917	0.699
DOC_USP7_MATH_1	48	52	PF00917	0.640
DOC_USP7_MATH_1	9	13	PF00917	0.710
DOC_USP7_MATH_1	96	100	PF00917	0.687
DOC_WW_Pin1_4	55	60	PF00397	0.620
DOC_WW_Pin1_4	71	76	PF00397	0.574
LIG_deltaCOP1_diTrp_1	159	165	PF00928	0.413
LIG_FHA_1	99	105	PF00498	0.574
LIG_FHA_2	19	25	PF00498	0.642
LIG_FHA_2	56	62	PF00498	0.562
LIG_LIR_Gen_1	113	123	PF02991	0.509
LIG_LIR_Gen_1	172	181	PF02991	0.429
LIG_LIR_Nem_3	113	118	PF02991	0.498
LIG_LIR_Nem_3	172	178	PF02991	0.442
LIG_Pex14_1	226	230	PF04695	0.425
LIG_PTB_Apo_2	109	116	PF02174	0.569
LIG_SH2_CRK	33	37	PF00017	0.499
LIG_SH3_1	187	193	PF00018	0.552
LIG_SH3_3	187	193	PF00018	0.592
LIG_TRAF2_1	58	61	PF00917	0.560
LIG_TYR_ITSM	171	178	PF00017	0.448
LIG_WRC_WIRS_1	199	204	PF05994	0.546
MOD_CDK_SPxxK_3	71	78	PF00069	0.590
MOD_CK1_1	10	16	PF00069	0.616
MOD_CK1_1	37	43	PF00069	0.729
MOD_CK1_1	51	57	PF00069	0.528
MOD_CK2_1	137	143	PF00069	0.431
MOD_CK2_1	54	60	PF00069	0.583
MOD_CMANNOS	162	165	PF00535	0.404
MOD_GlcNHglycan	12	15	PF01048	0.670
MOD_GlcNHglycan	90	93	PF01048	0.671
MOD_GlcNHglycan	97	101	PF01048	0.595
MOD_GSK3_1	3	10	PF00069	0.652
MOD_GSK3_1	50	57	PF00069	0.593
MOD_N-GLC_1	3	8	PF02516	0.600
MOD_NEK2_1	134	139	PF00069	0.526
MOD_NEK2_1	161	166	PF00069	0.460
MOD_NEK2_1	198	203	PF00069	0.435
MOD_NEK2_1	81	86	PF00069	0.497
MOD_NMyristoyl	1	7	PF02799	0.588
MOD_PIKK_1	128	134	PF00454	0.439
MOD_PKA_2	170	176	PF00069	0.541
MOD_PKA_2	87	93	PF00069	0.552
MOD_Plk_1	149	155	PF00069	0.433
MOD_Plk_1	48	54	PF00069	0.681
MOD_Plk_2-3	114	120	PF00069	0.481
MOD_Plk_4	170	176	PF00069	0.543
MOD_ProDKin_1	55	61	PF00069	0.615
MOD_ProDKin_1	71	77	PF00069	0.569
TRG_ENDOCYTIC_2	175	178	PF00928	0.496
TRG_ENDOCYTIC_2	33	36	PF00928	0.501
TRG_ENDOCYTIC_2	69	72	PF00928	0.482
TRG_Pf-PMV_PEXEL_1	155	159	PF00026	0.397
TRG_Pf-PMV_PEXEL_1	184	189	PF00026	0.561

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5D1	Leptomonas seymouri	71%	100%
A0A0S4J9I1	Bodo saltans	51%	100%
A0A1X0NL39	Trypanosomatidae	56%	100%
A0A3S5H5R9	Leishmania donovani	92%	100%
A4H4N3	Leishmania braziliensis	79%	100%
A4HSV9	Leishmania infantum	92%	100%
C9ZTH2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
E9AKU7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%