LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Deoxyribose-phosphate aldolase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Deoxyribose-phosphate aldolase
Gene product:
deoxyribose-phosphate aldolase, putative
Species:
Leishmania major
UniProt:
Q4QIW9_LEIMA
TriTrypDb:
LmjF.06.1070 , LMJLV39_060017100 , LMJSD75_060017300
Length:
281

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 3
Silverman et al. no yes: 0
Pissara et al. yes yes: 12
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 9
GO:0110165 cellular anatomical entity 1 9
Previous1Next

Expansion

Sequence features

Q4QIW9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIW9

Function

Biological processes
TermNameLevelCount
GO:0005975 carbohydrate metabolic process 3 2
GO:0006139 nucleobase-containing compound metabolic process 3 9
GO:0006725 cellular aromatic compound metabolic process 3 9
GO:0006753 nucleoside phosphate metabolic process 4 9
GO:0006793 phosphorus metabolic process 3 9
GO:0006796 phosphate-containing compound metabolic process 4 9
GO:0006807 nitrogen compound metabolic process 2 9
GO:0008152 metabolic process 1 9
GO:0009056 catabolic process 2 9
GO:0009117 nucleotide metabolic process 5 9
Previous1234Next
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 9
GO:0004139 deoxyribose-phosphate aldolase activity 5 9
GO:0016829 lyase activity 2 9
GO:0016830 carbon-carbon lyase activity 3 9
GO:0016832 aldehyde-lyase activity 4 9
Previous1Next

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 62 66 PF00656 0.662
CLV_NRD_NRD_1 19 21 PF00675 0.518
CLV_PCSK_KEX2_1 268 270 PF00082 0.370
CLV_PCSK_PC1ET2_1 268 270 PF00082 0.406
CLV_PCSK_SKI1_1 173 177 PF00082 0.328
CLV_PCSK_SKI1_1 190 194 PF00082 0.261
CLV_PCSK_SKI1_1 227 231 PF00082 0.323
DEG_Nend_UBRbox_4 1 3 PF02207 0.698
DEG_SPOP_SBC_1 218 222 PF00917 0.495
DOC_CKS1_1 133 138 PF01111 0.556
Previous12345…8Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PAW0 Leptomonas seymouri 69% 100%
A0A1X0NLL0 Trypanosomatidae 53% 100%
A0A3S5H5U0 Leishmania donovani 96% 100%
A0A422N1B0 Trypanosoma rangeli 61% 100%
A0AKA1 Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8) 47% 100%
A0KCV5 Burkholderia cenocepacia (strain HI2424) 48% 100%
A0KPE4 Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) 34% 100%
A0KU07 Shewanella sp. (strain ANA-3) 29% 100%
A0PVY3 Mycobacterium ulcerans (strain Agy99) 41% 100%
A0PYX5 Clostridium novyi (strain NT) 50% 100%
Previous12345…35Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS