LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
Nuclear Dbf2-related kinase
Species:
Leishmania major
UniProt:
Q4QIV8_LEIMA
TriTrypDb:
LmjF.06.1180 , LMJLV39_060018300 , LMJSD75_060018500 *
Length:
455

Annotations

LeishMANIAdb annotations

A large and apprently artificial collection of diverse kinetoplastid protein kinases. A subfamily has 2TM regions, but the majority is cytoplasmic.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005654 nucleoplasm 2 2
GO:0005737 cytoplasm 2 2
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 2
GO:0097014 ciliary plasm 5 2
GO:0099568 cytoplasmic region 3 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

Q4QIV8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIV8

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 11
GO:0006793 phosphorus metabolic process 3 11
GO:0006796 phosphate-containing compound metabolic process 4 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0007165 signal transduction 2 2
GO:0008152 metabolic process 1 11
GO:0009987 cellular process 1 11
GO:0016310 phosphorylation 5 11
GO:0018105 peptidyl-serine phosphorylation 6 2
GO:0018193 peptidyl-amino acid modification 5 2
GO:0018209 peptidyl-serine modification 6 2
GO:0019538 protein metabolic process 3 11
GO:0035556 intracellular signal transduction 3 2
GO:0036211 protein modification process 4 11
GO:0043170 macromolecule metabolic process 3 11
GO:0043412 macromolecule modification 4 11
GO:0044237 cellular metabolic process 2 11
GO:0044238 primary metabolic process 2 11
GO:0050789 regulation of biological process 2 2
GO:0050794 regulation of cellular process 3 2
GO:0065007 biological regulation 1 2
GO:0071704 organic substance metabolic process 2 11
GO:1901564 organonitrogen compound metabolic process 3 11
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 11
GO:0003824 catalytic activity 1 11
GO:0004672 protein kinase activity 3 11
GO:0004674 protein serine/threonine kinase activity 4 11
GO:0005488 binding 1 11
GO:0005524 ATP binding 5 11
GO:0016301 kinase activity 4 11
GO:0016740 transferase activity 2 11
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 11
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 11
GO:0017076 purine nucleotide binding 4 11
GO:0030554 adenyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032559 adenyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:0140096 catalytic activity, acting on a protein 2 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 141 145 PF00656 0.422
CLV_C14_Caspase3-7 255 259 PF00656 0.767
CLV_NRD_NRD_1 104 106 PF00675 0.341
CLV_NRD_NRD_1 20 22 PF00675 0.719
CLV_NRD_NRD_1 298 300 PF00675 0.417
CLV_PCSK_KEX2_1 102 104 PF00082 0.304
CLV_PCSK_KEX2_1 20 22 PF00082 0.725
CLV_PCSK_KEX2_1 221 223 PF00082 0.310
CLV_PCSK_KEX2_1 226 228 PF00082 0.543
CLV_PCSK_KEX2_1 361 363 PF00082 0.353
CLV_PCSK_KEX2_1 369 371 PF00082 0.353
CLV_PCSK_PC1ET2_1 102 104 PF00082 0.304
CLV_PCSK_PC1ET2_1 221 223 PF00082 0.310
CLV_PCSK_PC1ET2_1 226 228 PF00082 0.543
CLV_PCSK_PC1ET2_1 361 363 PF00082 0.383
CLV_PCSK_PC1ET2_1 369 371 PF00082 0.383
CLV_PCSK_PC7_1 222 228 PF00082 0.422
CLV_PCSK_SKI1_1 122 126 PF00082 0.383
CLV_PCSK_SKI1_1 167 171 PF00082 0.407
CLV_PCSK_SKI1_1 197 201 PF00082 0.303
CLV_PCSK_SKI1_1 279 283 PF00082 0.506
CLV_PCSK_SKI1_1 369 373 PF00082 0.415
CLV_PCSK_SKI1_1 37 41 PF00082 0.489
CLV_PCSK_SKI1_1 79 83 PF00082 0.321
DEG_SPOP_SBC_1 236 240 PF00917 0.714
DOC_CYCLIN_yCln2_LP_2 298 304 PF00134 0.408
DOC_CYCLIN_yCln2_LP_2 393 399 PF00134 0.502
DOC_MAPK_gen_1 112 118 PF00069 0.345
DOC_MAPK_gen_1 197 206 PF00069 0.310
DOC_PP1_RVXF_1 432 439 PF00149 0.483
DOC_PP2B_LxvP_1 393 396 PF13499 0.508
DOC_PP4_FxxP_1 381 384 PF00568 0.438
DOC_SPAK_OSR1_1 176 180 PF12202 0.317
DOC_USP7_MATH_1 128 132 PF00917 0.454
DOC_USP7_MATH_1 14 18 PF00917 0.773
DOC_USP7_MATH_1 185 189 PF00917 0.297
DOC_USP7_MATH_1 237 241 PF00917 0.634
DOC_USP7_MATH_1 243 247 PF00917 0.642
DOC_USP7_MATH_1 252 256 PF00917 0.778
DOC_USP7_MATH_1 33 37 PF00917 0.482
DOC_USP7_UBL2_3 102 106 PF12436 0.310
DOC_WW_Pin1_4 285 290 PF00397 0.310
LIG_14-3-3_CanoR_1 370 374 PF00244 0.409
LIG_APCC_ABBAyCdc20_2 434 440 PF00400 0.483
LIG_BIR_II_1 1 5 PF00653 0.634
LIG_BIR_III_2 258 262 PF00653 0.657
LIG_BRCT_BRCA1_1 173 177 PF00533 0.310
LIG_BRCT_BRCA1_1 219 223 PF00533 0.330
LIG_BRCT_BRCA1_1 35 39 PF00533 0.552
LIG_FHA_1 93 99 PF00498 0.373
LIG_FHA_2 22 28 PF00498 0.660
LIG_FHA_2 370 376 PF00498 0.422
LIG_LIR_Apic_2 232 236 PF02991 0.632
LIG_LIR_Apic_2 288 294 PF02991 0.310
LIG_LIR_Apic_2 317 323 PF02991 0.310
LIG_LIR_Apic_2 380 384 PF02991 0.372
LIG_LIR_Gen_1 144 155 PF02991 0.330
LIG_LIR_Gen_1 280 289 PF02991 0.408
LIG_LIR_Gen_1 372 381 PF02991 0.336
LIG_LIR_Gen_1 41 49 PF02991 0.636
LIG_LIR_Gen_1 65 74 PF02991 0.421
LIG_LIR_Nem_3 280 285 PF02991 0.408
LIG_LIR_Nem_3 307 311 PF02991 0.312
LIG_LIR_Nem_3 372 376 PF02991 0.296
LIG_LIR_Nem_3 407 413 PF02991 0.444
LIG_LIR_Nem_3 41 47 PF02991 0.670
LIG_LIR_Nem_3 65 71 PF02991 0.425
LIG_Pex14_2 82 86 PF04695 0.383
LIG_PTAP_UEV_1 415 420 PF05743 0.655
LIG_SH2_CRK 320 324 PF00017 0.310
LIG_SH2_CRK 44 48 PF00017 0.673
LIG_SH2_NCK_1 233 237 PF00017 0.597
LIG_SH2_PTP2 291 294 PF00017 0.310
LIG_SH2_SRC 233 236 PF00017 0.590
LIG_SH2_SRC 373 376 PF00017 0.454
LIG_SH2_SRC 397 400 PF00017 0.515
LIG_SH2_STAP1 253 257 PF00017 0.542
LIG_SH2_STAP1 316 320 PF00017 0.310
LIG_SH2_STAT3 346 349 PF00017 0.228
LIG_SH2_STAT5 147 150 PF00017 0.333
LIG_SH2_STAT5 178 181 PF00017 0.303
LIG_SH2_STAT5 291 294 PF00017 0.310
LIG_SH2_STAT5 397 400 PF00017 0.445
LIG_SH2_STAT5 409 412 PF00017 0.387
LIG_SH3_3 2 8 PF00018 0.664
LIG_SH3_3 283 289 PF00018 0.310
LIG_SH3_3 342 348 PF00018 0.471
LIG_SH3_3 393 399 PF00018 0.491
LIG_SH3_3 413 419 PF00018 0.324
LIG_TYR_ITIM 314 319 PF00017 0.310
LIG_UBA3_1 160 167 PF00899 0.310
LIG_WRC_WIRS_1 139 144 PF05994 0.348
MOD_CK1_1 327 333 PF00069 0.289
MOD_CK1_1 92 98 PF00069 0.454
MOD_CK2_1 185 191 PF00069 0.289
MOD_CK2_1 243 249 PF00069 0.705
MOD_CK2_1 369 375 PF00069 0.454
MOD_GlcNHglycan 208 211 PF01048 0.427
MOD_GlcNHglycan 248 253 PF01048 0.637
MOD_GlcNHglycan 415 419 PF01048 0.591
MOD_GlcNHglycan 445 448 PF01048 0.652
MOD_GSK3_1 104 111 PF00069 0.435
MOD_GSK3_1 138 145 PF00069 0.331
MOD_GSK3_1 244 251 PF00069 0.672
MOD_GSK3_1 281 288 PF00069 0.328
MOD_N-GLC_1 14 19 PF02516 0.763
MOD_N-GLC_1 330 335 PF02516 0.334
MOD_N-GLC_1 443 448 PF02516 0.592
MOD_NEK2_1 138 143 PF00069 0.310
MOD_NEK2_1 206 211 PF00069 0.367
MOD_NEK2_1 217 222 PF00069 0.273
MOD_NEK2_1 281 286 PF00069 0.346
MOD_NEK2_1 48 53 PF00069 0.570
MOD_NEK2_2 185 190 PF00069 0.310
MOD_PIKK_1 324 330 PF00454 0.422
MOD_PKA_1 369 375 PF00069 0.454
MOD_PKA_2 104 110 PF00069 0.324
MOD_PKA_2 369 375 PF00069 0.422
MOD_Plk_1 172 178 PF00069 0.310
MOD_Plk_1 248 254 PF00069 0.689
MOD_Plk_2-3 244 250 PF00069 0.687
MOD_Plk_4 142 148 PF00069 0.352
MOD_Plk_4 281 287 PF00069 0.328
MOD_Plk_4 43 49 PF00069 0.670
MOD_Plk_4 94 100 PF00069 0.454
MOD_ProDKin_1 285 291 PF00069 0.310
MOD_SUMO_rev_2 244 252 PF00179 0.753
MOD_SUMO_rev_2 402 410 PF00179 0.521
MOD_SUMO_rev_2 423 428 PF00179 0.632
TRG_DiLeu_BaLyEn_6 359 364 PF01217 0.383
TRG_ENDOCYTIC_2 139 142 PF00928 0.346
TRG_ENDOCYTIC_2 147 150 PF00928 0.292
TRG_ENDOCYTIC_2 316 319 PF00928 0.294
TRG_ENDOCYTIC_2 373 376 PF00928 0.422
TRG_ENDOCYTIC_2 44 47 PF00928 0.528
TRG_NLS_MonoExtC_3 101 106 PF00514 0.310
TRG_Pf-PMV_PEXEL_1 362 366 PF00026 0.319

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2S2 Leptomonas seymouri 25% 82%
A0A0N0P3N5 Leptomonas seymouri 26% 100%
A0A0N0P3Q8 Leptomonas seymouri 26% 100%
A0A0N0P4J7 Leptomonas seymouri 78% 100%
A0A0N0P787 Leptomonas seymouri 26% 100%
A0A0N0P8H5 Leptomonas seymouri 28% 100%
A0A0N0P953 Leptomonas seymouri 25% 95%
A0A0N1IHM7 Leptomonas seymouri 25% 77%
A0A0N1IM47 Leptomonas seymouri 22% 100%
A0A0N1IMD1 Leptomonas seymouri 26% 73%
A0A0N1PBE9 Leptomonas seymouri 25% 90%
A0A0N1PC31 Leptomonas seymouri 29% 100%
A0A0N1PDW7 Leptomonas seymouri 27% 100%
A0A0S4IQ75 Bodo saltans 24% 90%
A0A0S4IRZ7 Bodo saltans 24% 92%
A0A0S4ISS4 Bodo saltans 25% 100%
A0A0S4IX25 Bodo saltans 27% 70%
A0A0S4IX86 Bodo saltans 24% 100%
A0A0S4IZ51 Bodo saltans 23% 80%
A0A0S4J444 Bodo saltans 24% 100%
A0A0S4J4B3 Bodo saltans 28% 100%
A0A0S4J575 Bodo saltans 23% 73%
A0A0S4J6L4 Bodo saltans 29% 100%
A0A0S4J7K4 Bodo saltans 24% 94%
A0A0S4J7Q1 Bodo saltans 23% 76%
A0A0S4J842 Bodo saltans 25% 85%
A0A0S4JA09 Bodo saltans 27% 100%
A0A0S4JBR3 Bodo saltans 26% 100%
A0A0S4JCG2 Bodo saltans 26% 100%
A0A0S4JCK1 Bodo saltans 51% 97%
A0A0S4JER5 Bodo saltans 28% 100%
A0A0S4JI45 Bodo saltans 24% 70%
A0A0S4JI67 Bodo saltans 40% 100%
A0A0S4JIY0 Bodo saltans 26% 70%
A0A0S4JN19 Bodo saltans 23% 74%
A0A0S4JPZ1 Bodo saltans 22% 100%
A0A0S4JPZ7 Bodo saltans 25% 100%
A0A0S4JQA2 Bodo saltans 27% 77%
A0A0S4JTJ8 Bodo saltans 28% 100%
A0A0S4JWD5 Bodo saltans 25% 100%
A0A0S4KHR9 Bodo saltans 24% 100%
A0A0S4KMV7 Bodo saltans 24% 100%
A0A1X0NJV4 Trypanosomatidae 25% 89%
A0A1X0NLY7 Trypanosomatidae 23% 67%
A0A1X0NM94 Trypanosomatidae 25% 90%
A0A1X0NRF6 Trypanosomatidae 26% 83%
A0A1X0NTP1 Trypanosomatidae 29% 78%
A0A1X0NUQ4 Trypanosomatidae 26% 100%
A0A1X0NW24 Trypanosomatidae 24% 100%
A0A1X0NY93 Trypanosomatidae 27% 100%
A0A1X0NYK8 Trypanosomatidae 24% 100%
A0A1X0P020 Trypanosomatidae 24% 100%
A0A1X0P022 Trypanosomatidae 26% 71%
A0A1X0P078 Trypanosomatidae 24% 100%
A0A1X0P0R3 Trypanosomatidae 25% 75%
A0A1X0P150 Trypanosomatidae 28% 73%
A0A1X0P1A2 Trypanosomatidae 25% 98%
A0A1X0P290 Trypanosomatidae 25% 88%
A0A1X0P2H8 Trypanosomatidae 27% 100%
A0A1X0P3J5 Trypanosomatidae 29% 99%
A0A1X0P484 Trypanosomatidae 25% 66%
A0A1X0P4Z7 Trypanosomatidae 25% 82%
A0A1X0P527 Trypanosomatidae 21% 100%
A0A1X0P6L8 Trypanosomatidae 27% 72%
A0A1X0P795 Trypanosomatidae 27% 67%
A0A1X0P7V0 Trypanosomatidae 28% 100%
A0A1X0P8F7 Trypanosomatidae 38% 100%
A0A1X0P919 Trypanosomatidae 25% 100%
A0A2I0BVG8 Plasmodium falciparum (isolate NF54) 27% 87%
A0A3Q8IAQ1 Leishmania donovani 21% 100%
A0A3Q8IB30 Leishmania donovani 30% 100%
A0A3Q8IC87 Leishmania donovani 26% 100%
A0A3Q8IDK8 Leishmania donovani 25% 81%
A0A3Q8IFW0 Leishmania donovani 24% 100%
A0A3Q8IJM9 Leishmania donovani 26% 95%
A0A3Q8IND3 Leishmania donovani 23% 87%
A0A3Q8INQ4 Leishmania donovani 30% 100%
A0A3Q8IRT6 Leishmania donovani 28% 89%
A0A3Q8IU22 Leishmania donovani 27% 71%
A0A3R7K5P9 Trypanosoma rangeli 23% 100%
A0A3R7KRP1 Trypanosoma rangeli 24% 96%
A0A3R7M819 Trypanosoma rangeli 24% 100%
A0A3R7MHW5 Trypanosoma rangeli 26% 100%
A0A3R7MKG5 Trypanosoma rangeli 24% 100%
A0A3R7MKJ1 Trypanosoma rangeli 28% 84%
A0A3R7MPF2 Trypanosoma rangeli 27% 70%
A0A3R7N4D8 Trypanosoma rangeli 27% 100%
A0A3R7N5S4 Trypanosoma rangeli 25% 100%
A0A3R7RLL1 Trypanosoma rangeli 60% 100%
A0A3S5H5G0 Leishmania donovani 26% 100%
A0A3S5H5U5 Leishmania donovani 96% 100%
A0A3S7WTN9 Leishmania donovani 26% 100%
A0A3S7WV74 Leishmania donovani 25% 72%
A0A3S7WWE7 Leishmania donovani 25% 100%
A0A3S7X8Z8 Leishmania donovani 24% 93%
A0A3S7X9S2 Leishmania donovani 30% 100%
A0A422N0Q9 Trypanosoma rangeli 24% 74%
A0A422N215 Trypanosoma rangeli 26% 74%
A0A422N3Y6 Trypanosoma rangeli 22% 100%
A0A422NFN4 Trypanosoma rangeli 24% 90%
A0A422NUF0 Trypanosoma rangeli 22% 100%
A0A422P0J2 Trypanosoma rangeli 29% 100%
A0A422P0N6 Trypanosoma rangeli 26% 100%
A0A422P1R5 Trypanosoma rangeli 24% 100%
A0A422P270 Trypanosoma rangeli 37% 100%
A0A422P3N8 Trypanosoma rangeli 26% 78%
A0A422P4V9 Trypanosoma rangeli 30% 99%
A0A422P4X7 Trypanosoma rangeli 24% 90%
A1Z9X0 Drosophila melanogaster 30% 75%
A2VDV2 Bos taurus 40% 98%
A2YBX5 Oryza sativa subsp. indica 25% 77%
A2ZVI7 Oryza sativa subsp. japonica 25% 88%
A4H4S9 Leishmania braziliensis 89% 100%
A4H8C4 Leishmania braziliensis 25% 100%
A4H8F5 Leishmania braziliensis 23% 73%
A4H8V2 Leishmania braziliensis 24% 91%
A4H9L8 Leishmania braziliensis 30% 100%
A4HBL4 Leishmania braziliensis 23% 100%
A4HCD7 Leishmania braziliensis 25% 100%
A4HCE6 Leishmania braziliensis 22% 100%
A4HED7 Leishmania braziliensis 29% 100%
A4HFC9 Leishmania braziliensis 24% 69%
A4HFF3 Leishmania braziliensis 25% 91%
A4HI35 Leishmania braziliensis 28% 89%
A4HJW2 Leishmania braziliensis 25% 100%
A4HLN2 Leishmania braziliensis 25% 71%
A4HN71 Leishmania braziliensis 30% 100%
A4HSE2 Leishmania infantum 26% 100%
A4HWP5 Leishmania infantum 26% 100%
A4HXY2 Leishmania infantum 30% 100%
A4HZA2 Leishmania infantum 25% 100%
A4HZV1 Leishmania infantum 26% 100%
A4HZW8 Leishmania infantum 21% 100%
A4I1T4 Leishmania infantum 30% 100%
A4I349 Leishmania infantum 25% 81%
A4I5B1 Leishmania infantum 28% 89%
A4I7C4 Leishmania infantum 24% 100%
A4I967 Leishmania infantum 27% 71%
A4IB02 Leishmania infantum 25% 93%
A4IBT4 Leishmania infantum 30% 100%
A4IBT9 Leishmania infantum 30% 100%
A5A7I7 Solanum tuberosum 26% 82%
A5A7I8 Solanum tuberosum 26% 85%
A7MB74 Bos taurus 31% 100%
A8KBH6 Xenopus tropicalis 31% 68%
A8WUG4 Caenorhabditis briggsae 27% 76%
A8X6H4 Caenorhabditis briggsae 29% 100%
A8XJL7 Caenorhabditis briggsae 38% 96%
A8XNJ6 Caenorhabditis briggsae 30% 98%
B6DTC0 Bodo saltans 24% 100%
B9FKW9 Oryza sativa subsp. japonica 27% 87%
C6K3W8 Leptomonas seymouri 26% 86%
C9ZIW2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 73%
C9ZKE1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZL78 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 100%
C9ZLF2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 72%
C9ZMH9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 22% 100%
C9ZQL9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 71%
C9ZQP5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 99%
C9ZQR3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 89%
C9ZSI7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 100%
C9ZSU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 71%
C9ZTP2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 57% 98%
C9ZUU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 69%
C9ZW68 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
C9ZWI1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 100%
C9ZWK2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 21% 100%
C9ZX23 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 70%
C9ZXP1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 100%
D0A2M0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 97%
D0A2R4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 100%
D0A4H1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 75%
D0A5C6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A820 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 100%
E8NHS0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 22% 100%
E9ACW7 Leishmania major 25% 81%
E9ACY7 Leishmania major 24% 69%
E9AET0 Leishmania major 25% 100%
E9AFM1 Leishmania major 30% 100%
E9AG71 Leishmania infantum 96% 100%
E9AGR6 Leishmania infantum 25% 72%
E9AII8 Leishmania braziliensis 26% 100%
E9AKB7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9AKZ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
E9AQF3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9ARP5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9ARW5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 73%
E9ASL0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 94%
E9AUY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
E9AVR5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9AXW8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9AYR2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 69%
E9AZF6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 83%
E9B0K7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 89%
E9B2B7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
E9B408 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 71%
E9B5Y5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 92%
E9B745 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 95%
F1M7Y5 Rattus norvegicus 28% 76%
F4I4F2 Arabidopsis thaliana 28% 91%
J9W0G9 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 30% 79%
O00141 Homo sapiens 31% 100%
O13310 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 42% 97%
O15530 Homo sapiens 29% 82%
O15865 Plasmodium falciparum (isolate K1 / Thailand) 26% 89%
O19111 Oryctolagus cuniculus 30% 77%
O22932 Arabidopsis thaliana 28% 100%
O42626 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 33% 73%
O49717 Arabidopsis thaliana 25% 82%
O55173 Rattus norvegicus 30% 81%
O60285 Homo sapiens 25% 69%
O64682 Arabidopsis thaliana 27% 100%
O70150 Rattus norvegicus 27% 100%
O77676 Oryctolagus cuniculus 30% 68%
O94487 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 35% 73%
P00516 Bos taurus 30% 68%
P00517 Bos taurus 27% 100%
P04409 Bos taurus 30% 68%
P05126 Bos taurus 29% 68%
P05128 Bos taurus 29% 67%
P05130 Drosophila melanogaster 29% 67%
P05131 Bos taurus 27% 100%
P05383 Sus scrofa 27% 100%
P05696 Rattus norvegicus 30% 68%
P05771 Homo sapiens 29% 68%
P05772 Oryctolagus cuniculus 29% 68%
P06244 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 100%
P06245 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 100%
P08414 Mus musculus 29% 97%
P09215 Rattus norvegicus 29% 68%
P09217 Rattus norvegicus 30% 77%
P0C605 Mus musculus 30% 68%
P10102 Oryctolagus cuniculus 30% 68%
P10666 Xenopus laevis 31% 72%
P11801 Homo sapiens 27% 100%
P12370 Drosophila melanogaster 28% 100%
P12688 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 33% 67%
P13234 Rattus norvegicus 28% 96%
P15792 Phaseolus vulgaris 27% 75%
P16911 Drosophila melanogaster 30% 100%
P16912 Drosophila melanogaster 27% 78%
P17252 Homo sapiens 30% 68%
P17612 Homo sapiens 28% 100%
P18961 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 32% 67%
P20444 Mus musculus 29% 68%
P21137 Caenorhabditis elegans 30% 100%
P22204 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 80%
P22612 Homo sapiens 28% 100%
P22694 Homo sapiens 27% 100%
P23298 Mus musculus 31% 67%
P23443 Homo sapiens 30% 87%
P24723 Homo sapiens 30% 67%
P25321 Cricetulus griseus 28% 100%
P27791 Rattus norvegicus 27% 100%
P28178 Dictyostelium discoideum 30% 95%
P28582 Daucus carota 26% 86%
P28583 Glycine max 26% 90%
P28867 Mus musculus 29% 68%
P31748 AKT8 murine leukemia virus 29% 91%
P31749 Homo sapiens 29% 95%
P31750 Mus musculus 29% 95%
P31751 Homo sapiens 29% 95%
P32328 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 31% 81%
P34099 Dictyostelium discoideum 27% 70%
P34101 Dictyostelium discoideum 29% 76%
P34947 Homo sapiens 26% 77%
P36887 Sus scrofa 27% 100%
P38070 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 87%
P38679 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 41% 76%
P40376 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 89%
P41743 Homo sapiens 28% 76%
P42818 Arabidopsis thaliana 30% 98%
P43249 Bos taurus 27% 77%
P45894 Caenorhabditis elegans 26% 77%
P47196 Rattus norvegicus 29% 95%
P47197 Rattus norvegicus 30% 95%
P49673 Ascaris suum 25% 100%
P51817 Homo sapiens 30% 100%
P53681 Daucus carota 29% 76%
P53682 Oryza sativa subsp. japonica 25% 85%
P54265 Mus musculus 35% 72%
P54644 Dictyostelium discoideum 30% 100%
P62343 Plasmodium falciparum (isolate K1 / Thailand) 27% 87%
P62344 Plasmodium falciparum (isolate 3D7) 27% 87%
P67998 Oryctolagus cuniculus 30% 87%
P67999 Rattus norvegicus 30% 87%
P68180 Cricetulus griseus 29% 100%
P68181 Mus musculus 29% 100%
P68182 Rattus norvegicus 29% 100%
P68403 Rattus norvegicus 29% 68%
P68404 Mus musculus 29% 68%
P83099 Drosophila melanogaster 29% 68%
P90980 Caenorhabditis elegans 30% 67%
P93759 Arabidopsis thaliana 27% 86%
Q01314 Bos taurus 30% 95%
Q02956 Mus musculus 30% 77%
Q05513 Homo sapiens 30% 77%
Q05655 Homo sapiens 30% 67%
Q05999 Arabidopsis thaliana 27% 79%
Q06226 Rattus norvegicus 31% 100%
Q06850 Arabidopsis thaliana 26% 75%
Q09013 Homo sapiens 36% 72%
Q09831 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 80%
Q09898 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 33% 75%
Q0DCT8 Oryza sativa subsp. japonica 25% 77%
Q0DYK7 Oryza sativa subsp. japonica 27% 83%
Q0V7M1 Bos taurus 27% 100%
Q0VD22 Bos taurus 26% 94%
Q12701 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 77%
Q12706 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
Q13976 Homo sapiens 30% 68%
Q14012 Homo sapiens 28% 100%
Q15208 Homo sapiens 40% 98%
Q16566 Homo sapiens 28% 96%
Q16974 Aplysia californica 31% 70%
Q17941 Caenorhabditis elegans 31% 84%
Q19266 Caenorhabditis elegans 27% 76%
Q1PFB9 Arabidopsis thaliana 29% 82%
Q25378 Lytechinus pictus 30% 69%
Q27687 Leishmania major 30% 92%
Q2L6W9 Caenorhabditis elegans 40% 96%
Q2LZZ7 Drosophila pseudoobscura pseudoobscura 44% 99%
Q2PJ68 Caenorhabditis elegans 31% 98%
Q2QM77 Oryza sativa subsp. japonica 30% 94%
Q2QQR2 Oryza sativa subsp. japonica 28% 74%
Q2QVG8 Oryza sativa subsp. japonica 26% 81%
Q2QX45 Oryza sativa subsp. japonica 27% 87%
Q2QY37 Oryza sativa subsp. japonica 27% 84%
Q2RAV0 Oryza sativa subsp. japonica 27% 84%
Q38868 Arabidopsis thaliana 25% 84%
Q38869 Arabidopsis thaliana 27% 91%
Q38871 Arabidopsis thaliana 26% 82%
Q38872 Arabidopsis thaliana 26% 84%
Q38873 Arabidopsis thaliana 28% 85%
Q39016 Arabidopsis thaliana 26% 92%
Q39030 Arabidopsis thaliana 30% 97%
Q39183 Arabidopsis thaliana 26% 78%
Q3E9C0 Arabidopsis thaliana 26% 87%
Q42396 Arabidopsis thaliana 25% 93%
Q42438 Arabidopsis thaliana 27% 85%
Q42479 Arabidopsis thaliana 25% 86%
Q4KTY1 Pinctada fucata 26% 100%
Q4Q0B0 Leishmania major 22% 100%
Q4Q416 Leishmania major 26% 71%
Q4Q5T9 Leishmania major 24% 100%
Q4Q7M5 Leishmania major 27% 89%
Q4Q9K2 Leishmania major 30% 100%
Q4QBQ2 Leishmania major 24% 100%
Q4QBR6 Leishmania major 27% 100%
Q4QCK0 Leishmania major 25% 100%
Q4QDK7 Leishmania major 25% 72%
Q4QF23 Leishmania major 26% 100%
Q4QJJ0 Leishmania major 27% 100%
Q4R633 Macaca fascicularis 32% 100%
Q4V3C8 Arabidopsis thaliana 29% 94%
Q53P85 Oryza sativa subsp. japonica 26% 89%
Q54C18 Dictyostelium discoideum 27% 88%
Q54IF2 Dictyostelium discoideum 30% 71%
Q54IH8 Dictyostelium discoideum 38% 84%
Q54L81 Dictyostelium discoideum 31% 98%
Q54PB4 Dictyostelium discoideum 27% 95%
Q54SJ5 Dictyostelium discoideum 29% 100%
Q54UZ1 Dictyostelium discoideum 26% 100%
Q54WX4 Dictyostelium discoideum 25% 100%
Q54Y26 Dictyostelium discoideum 43% 86%
Q59S66 Candida albicans (strain SC5314 / ATCC MYA-2876) 26% 86%
Q5BKK4 Xenopus tropicalis 29% 100%
Q5JLS2 Oryza sativa subsp. japonica 29% 84%
Q5PU49 Canis lupus familiaris 28% 68%
Q5Q0U5 Fundulus heteroclitus 31% 100%
Q5QNM6 Oryza sativa subsp. japonica 27% 89%
Q5R4K9 Pongo abelii 28% 76%
Q5R7A7 Pongo abelii 27% 92%
Q5R7G9 Pongo abelii 25% 72%
Q5R8M1 Pongo abelii 40% 98%
Q5VQQ5 Oryza sativa subsp. japonica 28% 88%
Q5ZJH6 Gallus gallus 28% 97%
Q60823 Mus musculus 29% 95%
Q62074 Mus musculus 28% 76%
Q62833 Rattus norvegicus 27% 77%
Q63450 Rattus norvegicus 28% 100%
Q63484 Rattus norvegicus 30% 95%
Q641K5 Mus musculus 25% 69%
Q64617 Rattus norvegicus 31% 67%
Q64FQ2 Arabidopsis thaliana 29% 87%
Q66HE5 Rattus norvegicus 25% 72%
Q6A1A2 Homo sapiens 29% 100%
Q6C3J2 Yarrowia lipolytica (strain CLIB 122 / E 150) 26% 100%
Q6CFS5 Yarrowia lipolytica (strain CLIB 122 / E 150) 40% 77%
Q6F3A6 Oryza sativa subsp. japonica 28% 76%
Q6GLY8 Xenopus laevis 30% 100%
Q6GPN6 Xenopus laevis 29% 100%
Q6I587 Oryza sativa subsp. japonica 26% 84%
Q6I5I8 Oryza sativa subsp. japonica 27% 83%
Q6IP76 Xenopus laevis 29% 94%
Q6K968 Oryza sativa subsp. japonica 26% 83%
Q6NLQ6 Arabidopsis thaliana 27% 85%
Q6P2M8 Homo sapiens 27% 100%
Q6PHR2 Homo sapiens 27% 96%
Q6TGC6 Pneumocystis carinii 43% 90%
Q6TJY3 Bos taurus 30% 86%
Q6U1I9 Gallus gallus 31% 100%
Q755C4 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 25% 100%
Q75GK4 Oryza sativa subsp. japonica 28% 100%
Q7JP68 Caenorhabditis elegans 27% 100%
Q7LZQ8 Xenopus laevis 31% 68%
Q7SY24 Danio rerio 30% 68%
Q7TNJ7 Rattus norvegicus 28% 96%
Q7TSE6 Mus musculus 39% 98%
Q7XIM0 Oryza sativa subsp. japonica 26% 80%
Q7XSQ5 Oryza sativa subsp. japonica 26% 85%
Q7YRC6 Bos taurus 25% 100%
Q7ZTW4 Danio rerio 31% 100%
Q7ZX15 Xenopus laevis 29% 94%
Q84SL0 Oryza sativa subsp. japonica 27% 83%
Q852N6 Oryza sativa subsp. japonica 26% 79%
Q869W6 Dictyostelium discoideum 30% 100%
Q86AD7 Dictyostelium discoideum 27% 100%
Q86UX6 Homo sapiens 27% 94%
Q8BGW6 Mus musculus 25% 100%
Q8BSK8 Mus musculus 30% 87%
Q8BW96 Mus musculus 28% 100%
Q8BZN4 Mus musculus 25% 71%
Q8ICR0 Plasmodium falciparum (isolate 3D7) 26% 89%
Q8INB9 Drosophila melanogaster 30% 74%
Q8IU85 Homo sapiens 28% 100%
Q8LPZ7 Oryza sativa subsp. japonica 27% 83%
Q8MJ44 Canis lupus familiaris 27% 100%
Q8MYF1 Dictyostelium discoideum 31% 100%
Q8R4U9 Rattus norvegicus 29% 100%
Q8R4V0 Rattus norvegicus 27% 92%
Q8RWL2 Arabidopsis thaliana 28% 85%
Q8SRK8 Encephalitozoon cuniculi (strain GB-M1) 28% 100%
Q8VEB1 Mus musculus 27% 77%
Q8W1D5 Arabidopsis thaliana 27% 93%
Q8W490 Arabidopsis thaliana 28% 97%
Q8WU08 Homo sapiens 26% 100%
Q90XF2 Danio rerio 28% 77%
Q91VB2 Mus musculus 28% 95%
Q91VJ4 Mus musculus 40% 98%
Q91YA2 Mus musculus 27% 100%
Q91YS8 Mus musculus 28% 100%
Q922R0 Mus musculus 29% 100%
Q924X7 Mus musculus 26% 93%
Q940H6 Arabidopsis thaliana 28% 100%
Q965G5 Caenorhabditis elegans 27% 100%
Q96BR1 Homo sapiens 27% 92%
Q96NX5 Homo sapiens 28% 96%
Q98TY9 Xenopus laevis 30% 95%
Q9BYT3 Homo sapiens 26% 89%
Q9C098 Homo sapiens 26% 70%
Q9C6P3 Arabidopsis thaliana 26% 87%
Q9C8M5 Arabidopsis thaliana 29% 96%
Q9ERE3 Mus musculus 27% 92%
Q9FG74 Arabidopsis thaliana 26% 91%
Q9FJ55 Arabidopsis thaliana 27% 94%
Q9FMP5 Arabidopsis thaliana 27% 86%
Q9FX86 Arabidopsis thaliana 28% 75%
Q9FXQ3 Oryza sativa subsp. japonica 25% 83%
Q9GM70 Oryctolagus cuniculus 28% 100%
Q9GNR4 Leishmania major 30% 100%
Q9H093 Homo sapiens 25% 72%
Q9HBY8 Homo sapiens 30% 100%
Q9LET1 Arabidopsis thaliana 30% 79%
Q9LJL9 Arabidopsis thaliana 27% 76%
Q9LP51 Arabidopsis thaliana 28% 88%
Q9LSF1 Arabidopsis thaliana 29% 100%
Q9LT38 Arabidopsis thaliana 29% 100%
Q9LTW5 Arabidopsis thaliana 29% 79%
Q9LUL2 Arabidopsis thaliana 27% 95%
Q9M101 Arabidopsis thaliana 25% 88%
Q9M9V8 Arabidopsis thaliana 26% 83%
Q9MZD9 Ovis aries 27% 100%
Q9NAH6 Caenorhabditis elegans 29% 83%
Q9NBK5 Drosophila melanogaster 44% 98%
Q9P7J8 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 32% 80%
Q9QYK9 Mus musculus 27% 100%
Q9QZS5 Mus musculus 29% 100%
Q9SCS2 Arabidopsis thaliana 29% 76%
Q9SEZ7 Arabidopsis thaliana 27% 97%
Q9SIQ7 Arabidopsis thaliana 28% 78%
Q9SJ61 Arabidopsis thaliana 26% 88%
Q9SN43 Arabidopsis thaliana 28% 93%
Q9SSF8 Arabidopsis thaliana 26% 84%
Q9SUA3 Arabidopsis thaliana 25% 90%
Q9SYB9 Arabidopsis thaliana 28% 100%
Q9SZM3 Arabidopsis thaliana 27% 94%
Q9TXJ0 Caenorhabditis elegans 28% 100%
Q9UBS0 Homo sapiens 31% 94%
Q9USX7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 87%
Q9WUA6 Mus musculus 30% 95%
Q9WVC6 Mus musculus 31% 100%
Q9XF67 Arabidopsis thaliana 28% 93%
Q9XT18 Oryctolagus cuniculus 31% 100%
Q9XTG7 Caenorhabditis elegans 29% 86%
Q9Y1J3 Caenorhabditis elegans 27% 72%
Q9Y243 Homo sapiens 30% 95%
Q9Y2H1 Homo sapiens 36% 98%
Q9Y2U5 Homo sapiens 29% 74%
Q9Y7J6 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 83%
Q9Z1M4 Mus musculus 30% 94%
Q9Z2A0 Mus musculus 30% 81%
Q9ZSA2 Arabidopsis thaliana 26% 86%
Q9ZV15 Arabidopsis thaliana 28% 78%
V5B871 Trypanosoma cruzi 25% 100%
V5BAZ8 Trypanosoma cruzi 26% 100%
V5BCH2 Trypanosoma cruzi 29% 100%
V5BCN4 Trypanosoma cruzi 24% 74%
V5BH88 Trypanosoma cruzi 27% 83%
V5BHW8 Trypanosoma cruzi 24% 72%
V5BI43 Trypanosoma cruzi 24% 91%
V5BL06 Trypanosoma cruzi 27% 70%
V5BLT9 Trypanosoma cruzi 24% 100%
V5BP88 Trypanosoma cruzi 26% 98%
V5BPK4 Trypanosoma cruzi 30% 75%
V5BQH6 Trypanosoma cruzi 41% 100%
V5BSA6 Trypanosoma cruzi 25% 69%
V5BU83 Trypanosoma cruzi 25% 89%
V5D179 Trypanosoma cruzi 25% 75%
V5DAY8 Trypanosoma cruzi 28% 100%
V5DC40 Trypanosoma cruzi 25% 83%
V5DCD4 Trypanosoma cruzi 25% 78%
V5DMJ4 Trypanosoma cruzi 24% 100%
V5DPP5 Trypanosoma cruzi 61% 100%
V5DQT5 Trypanosoma cruzi 29% 99%
V5DTI3 Trypanosoma cruzi 26% 72%
V5DUH0 Trypanosoma cruzi 24% 83%
W0LYS5 Macrobrachium nipponense 27% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS