CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIU0_LEIMA

TriTrypDb:

LmjF.07.0040 , LMJLV39_070005700 , LMJSD75_070005700

Length:

315

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIU0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIU0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.602
CLV_NRD_NRD_1	225	227	PF00675	0.746
CLV_NRD_NRD_1	242	244	PF00675	0.508
CLV_NRD_NRD_1	300	302	PF00675	0.705
CLV_PCSK_FUR_1	298	302	PF00082	0.798
CLV_PCSK_KEX2_1	240	242	PF00082	0.729
CLV_PCSK_KEX2_1	297	299	PF00082	0.686
CLV_PCSK_KEX2_1	300	302	PF00082	0.700
CLV_PCSK_KEX2_1	54	56	PF00082	0.535
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.729
CLV_PCSK_PC1ET2_1	297	299	PF00082	0.686
CLV_PCSK_PC1ET2_1	54	56	PF00082	0.535
CLV_PCSK_SKI1_1	103	107	PF00082	0.622
CLV_PCSK_SKI1_1	154	158	PF00082	0.481
CLV_PCSK_SKI1_1	213	217	PF00082	0.670
CLV_PCSK_SKI1_1	226	230	PF00082	0.650
CLV_PCSK_SKI1_1	301	305	PF00082	0.803
CLV_PCSK_SKI1_1	78	82	PF00082	0.445
DEG_APCC_DBOX_1	149	157	PF00400	0.514
DEG_APCC_DBOX_1	212	220	PF00400	0.671
DEG_APCC_DBOX_1	77	85	PF00400	0.440
DEG_SCF_FBW7_1	178	184	PF00400	0.561
DOC_CKS1_1	178	183	PF01111	0.714
DOC_CYCLIN_RxL_1	75	85	PF00134	0.451
DOC_MAPK_gen_1	103	113	PF00069	0.600
DOC_MAPK_gen_1	150	158	PF00069	0.496
DOC_MAPK_gen_1	297	307	PF00069	0.699
DOC_MAPK_gen_1	54	63	PF00069	0.567
DOC_MAPK_MEF2A_6	106	115	PF00069	0.496
DOC_MAPK_MEF2A_6	298	307	PF00069	0.679
DOC_PP1_RVXF_1	131	137	PF00149	0.467
DOC_PP1_RVXF_1	215	222	PF00149	0.592
DOC_USP7_MATH_1	169	173	PF00917	0.690
DOC_USP7_MATH_1	201	205	PF00917	0.646
DOC_USP7_MATH_1	64	68	PF00917	0.508
DOC_WW_Pin1_4	120	125	PF00397	0.478
DOC_WW_Pin1_4	177	182	PF00397	0.692
DOC_WW_Pin1_4	271	276	PF00397	0.777
DOC_WW_Pin1_4	291	296	PF00397	0.550
DOC_WW_Pin1_4	307	312	PF00397	0.696
DOC_WW_Pin1_4	4	9	PF00397	0.618
LIG_14-3-3_CanoR_1	101	108	PF00244	0.622
LIG_14-3-3_CanoR_1	119	123	PF00244	0.330
LIG_14-3-3_CanoR_1	226	236	PF00244	0.660
LIG_14-3-3_CanoR_1	300	306	PF00244	0.691
LIG_Actin_WH2_2	104	121	PF00022	0.516
LIG_BIR_II_1	1	5	PF00653	0.574
LIG_FHA_1	121	127	PF00498	0.467
LIG_FHA_1	21	27	PF00498	0.616
LIG_FHA_1	228	234	PF00498	0.656
LIG_FHA_1	280	286	PF00498	0.718
LIG_FHA_1	302	308	PF00498	0.806
LIG_FHA_1	57	63	PF00498	0.546
LIG_FHA_1	74	80	PF00498	0.503
LIG_FHA_2	143	149	PF00498	0.584
LIG_FHA_2	182	188	PF00498	0.724
LIG_FHA_2	274	280	PF00498	0.601
LIG_FHA_2	84	90	PF00498	0.441
LIG_NRBOX	86	92	PF00104	0.546
LIG_SH2_STAT5	236	239	PF00017	0.622
LIG_SH3_2	308	313	PF14604	0.701
LIG_SH3_3	108	114	PF00018	0.445
LIG_SH3_3	175	181	PF00018	0.787
LIG_SH3_3	203	209	PF00018	0.706
LIG_SH3_3	269	275	PF00018	0.791
LIG_SH3_3	302	308	PF00018	0.717
LIG_SUMO_SIM_par_1	288	294	PF11976	0.677
LIG_SxIP_EBH_1	226	239	PF03271	0.734
LIG_UBA3_1	289	297	PF00899	0.671
MOD_CDC14_SPxK_1	294	297	PF00782	0.671
MOD_CDC14_SPxK_1	310	313	PF00782	0.707
MOD_CDK_SPxK_1	291	297	PF00069	0.672
MOD_CDK_SPxK_1	307	313	PF00069	0.702
MOD_CDK_SPxxK_3	291	298	PF00069	0.674
MOD_CK1_1	142	148	PF00069	0.653
MOD_CK1_1	252	258	PF00069	0.787
MOD_CK1_1	69	75	PF00069	0.649
MOD_CK2_1	134	140	PF00069	0.504
MOD_CK2_1	142	148	PF00069	0.361
MOD_CK2_1	181	187	PF00069	0.713
MOD_CK2_1	191	197	PF00069	0.691
MOD_CK2_1	83	89	PF00069	0.440
MOD_GlcNHglycan	140	144	PF01048	0.657
MOD_GlcNHglycan	171	174	PF01048	0.688
MOD_GlcNHglycan	230	233	PF01048	0.646
MOD_GlcNHglycan	254	257	PF01048	0.623
MOD_GlcNHglycan	66	69	PF01048	0.663
MOD_GlcNHglycan	92	95	PF01048	0.466
MOD_GSK3_1	118	125	PF00069	0.591
MOD_GSK3_1	177	184	PF00069	0.601
MOD_GSK3_1	22	29	PF00069	0.410
MOD_GSK3_1	228	235	PF00069	0.650
MOD_GSK3_1	271	278	PF00069	0.700
MOD_GSK3_1	69	76	PF00069	0.637
MOD_N-GLC_1	301	306	PF02516	0.729
MOD_N-GLC_1	72	77	PF02516	0.541
MOD_N-GLC_2	200	202	PF02516	0.568
MOD_NEK2_1	117	122	PF00069	0.485
MOD_NEK2_1	139	144	PF00069	0.646
MOD_NEK2_1	168	173	PF00069	0.623
MOD_NEK2_1	90	95	PF00069	0.459
MOD_PIKK_1	56	62	PF00454	0.525
MOD_PKA_1	226	232	PF00069	0.514
MOD_PKA_2	118	124	PF00069	0.486
MOD_PKA_2	169	175	PF00069	0.728
MOD_PKA_2	56	62	PF00069	0.564
MOD_PKB_1	241	249	PF00069	0.650
MOD_PKB_1	299	307	PF00069	0.766
MOD_PKB_1	99	107	PF00069	0.612
MOD_Plk_1	217	223	PF00069	0.642
MOD_Plk_1	244	250	PF00069	0.654
MOD_Plk_1	26	32	PF00069	0.374
MOD_Plk_1	301	307	PF00069	0.807
MOD_Plk_2-3	22	28	PF00069	0.566
MOD_Plk_4	122	128	PF00069	0.572
MOD_Plk_4	232	238	PF00069	0.617
MOD_ProDKin_1	120	126	PF00069	0.476
MOD_ProDKin_1	177	183	PF00069	0.693
MOD_ProDKin_1	271	277	PF00069	0.778
MOD_ProDKin_1	291	297	PF00069	0.551
MOD_ProDKin_1	307	313	PF00069	0.702
MOD_ProDKin_1	4	10	PF00069	0.616
MOD_SUMO_rev_2	194	201	PF00179	0.798
TRG_DiLeu_BaEn_1	58	63	PF01217	0.606
TRG_DiLeu_BaLyEn_6	75	80	PF01217	0.469
TRG_ER_diArg_1	241	243	PF00400	0.659
TRG_ER_diArg_1	298	301	PF00400	0.692
TRG_NLS_Bipartite_1	226	244	PF00514	0.741
TRG_NLS_MonoCore_2	239	244	PF00514	0.756
TRG_NLS_MonoCore_2	296	301	PF00514	0.677
TRG_NLS_MonoExtC_3	239	245	PF00514	0.759
TRG_NLS_MonoExtC_3	296	301	PF00514	0.687
TRG_NLS_MonoExtN_4	295	301	PF00514	0.685
TRG_Pf-PMV_PEXEL_1	288	293	PF00026	0.694
TRG_Pf-PMV_PEXEL_1	301	306	PF00026	0.564
TRG_Pf-PMV_PEXEL_1	78	82	PF00026	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD5	Leptomonas seymouri	39%	100%
A0A3S7WPQ1	Leishmania donovani	90%	100%
A4H4U7	Leishmania braziliensis	74%	100%
A4HT26	Leishmania infantum	90%	100%
E9AL14	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%