AP-2 complex subunit alpha

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

alpha-adaptin-like protein

Species:

Leishmania major

UniProt:

Q4QIT9_LEIMA

TriTrypDb:

LmjF.07.0050 , LMJLV39_070005800 , LMJSD75_070005800

Length:

961

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0030119	AP-type membrane coat adaptor complex	3	9
GO:0030122	AP-2 adaptor complex	4	9
GO:0030131	clathrin adaptor complex	4	9
GO:0032991	protein-containing complex	1	9
GO:0098796	membrane protein complex	2	9
GO:0098797	plasma membrane protein complex	3	9

Expansion

Sequence features

Q4QIT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIT9

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	9
GO:0006886	intracellular protein transport	4	9
GO:0006897	endocytosis	5	9
GO:0006898	receptor-mediated endocytosis	6	9
GO:0008104	protein localization	4	9
GO:0009987	cellular process	1	9
GO:0015031	protein transport	4	9
GO:0016192	vesicle-mediated transport	4	9
GO:0033036	macromolecule localization	2	9
GO:0045184	establishment of protein localization	3	9
GO:0046907	intracellular transport	3	9
GO:0051179	localization	1	9
GO:0051234	establishment of localization	2	9
GO:0051641	cellular localization	2	9
GO:0051649	establishment of localization in cell	3	9
GO:0070727	cellular macromolecule localization	3	9
GO:0071702	organic substance transport	4	9
GO:0071705	nitrogen compound transport	4	9
GO:0072583	clathrin-dependent endocytosis	7	9

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	9
GO:0005515	protein binding	2	9
GO:0030276	clathrin binding	3	9
GO:0030674	protein-macromolecule adaptor activity	2	9
GO:0035615	clathrin adaptor activity	4	9
GO:0060090	molecular adaptor activity	1	9
GO:0140312	cargo adaptor activity	3	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	192	196	PF00656	0.416
CLV_NRD_NRD_1	14	16	PF00675	0.467
CLV_NRD_NRD_1	170	172	PF00675	0.396
CLV_NRD_NRD_1	278	280	PF00675	0.410
CLV_NRD_NRD_1	391	393	PF00675	0.416
CLV_NRD_NRD_1	48	50	PF00675	0.335
CLV_NRD_NRD_1	494	496	PF00675	0.427
CLV_NRD_NRD_1	652	654	PF00675	0.731
CLV_NRD_NRD_1	669	671	PF00675	0.592
CLV_NRD_NRD_1	722	724	PF00675	0.526
CLV_NRD_NRD_1	873	875	PF00675	0.530
CLV_PCSK_KEX2_1	14	16	PF00082	0.522
CLV_PCSK_KEX2_1	343	345	PF00082	0.397
CLV_PCSK_KEX2_1	484	486	PF00082	0.334
CLV_PCSK_KEX2_1	625	627	PF00082	0.609
CLV_PCSK_KEX2_1	652	654	PF00082	0.751
CLV_PCSK_KEX2_1	668	670	PF00082	0.778
CLV_PCSK_KEX2_1	721	723	PF00082	0.546
CLV_PCSK_PC1ET2_1	343	345	PF00082	0.416
CLV_PCSK_PC1ET2_1	484	486	PF00082	0.334
CLV_PCSK_PC1ET2_1	625	627	PF00082	0.609
CLV_PCSK_PC1ET2_1	652	654	PF00082	0.757
CLV_PCSK_PC1ET2_1	668	670	PF00082	0.568
CLV_PCSK_SKI1_1	112	116	PF00082	0.346
CLV_PCSK_SKI1_1	14	18	PF00082	0.488
CLV_PCSK_SKI1_1	160	164	PF00082	0.384
CLV_PCSK_SKI1_1	230	234	PF00082	0.360
CLV_PCSK_SKI1_1	273	277	PF00082	0.368
CLV_PCSK_SKI1_1	280	284	PF00082	0.368
CLV_PCSK_SKI1_1	287	291	PF00082	0.368
CLV_PCSK_SKI1_1	327	331	PF00082	0.416
CLV_PCSK_SKI1_1	393	397	PF00082	0.394
CLV_PCSK_SKI1_1	55	59	PF00082	0.334
CLV_PCSK_SKI1_1	568	572	PF00082	0.334
CLV_PCSK_SKI1_1	669	673	PF00082	0.782
CLV_PCSK_SKI1_1	722	726	PF00082	0.483
CLV_PCSK_SKI1_1	732	736	PF00082	0.450
DEG_APCC_DBOX_1	669	677	PF00400	0.536
DEG_APCC_DBOX_1	720	728	PF00400	0.523
DEG_Nend_UBRbox_2	1	3	PF02207	0.513
DOC_CKS1_1	845	850	PF01111	0.533
DOC_CYCLIN_RxL_1	119	127	PF00134	0.416
DOC_CYCLIN_RxL_1	157	165	PF00134	0.416
DOC_CYCLIN_RxL_1	719	728	PF00134	0.524
DOC_CYCLIN_yCln2_LP_2	62	68	PF00134	0.334
DOC_MAPK_DCC_7	495	505	PF00069	0.350
DOC_MAPK_gen_1	160	166	PF00069	0.373
DOC_MAPK_gen_1	171	179	PF00069	0.282
DOC_MAPK_gen_1	271	278	PF00069	0.368
DOC_MAPK_gen_1	392	400	PF00069	0.334
DOC_MAPK_gen_1	441	450	PF00069	0.407
DOC_MAPK_gen_1	484	491	PF00069	0.351
DOC_MAPK_gen_1	49	58	PF00069	0.334
DOC_MAPK_gen_1	763	773	PF00069	0.505
DOC_MAPK_gen_1	830	838	PF00069	0.355
DOC_MAPK_gen_1	918	926	PF00069	0.528
DOC_MAPK_MEF2A_6	271	278	PF00069	0.368
DOC_MAPK_MEF2A_6	392	400	PF00069	0.334
DOC_MAPK_MEF2A_6	428	437	PF00069	0.334
DOC_MAPK_MEF2A_6	444	452	PF00069	0.334
DOC_MAPK_MEF2A_6	496	505	PF00069	0.372
DOC_MAPK_MEF2A_6	766	775	PF00069	0.502
DOC_MAPK_MEF2A_6	813	820	PF00069	0.475
DOC_MAPK_NFAT4_5	271	279	PF00069	0.368
DOC_MAPK_NFAT4_5	428	436	PF00069	0.334
DOC_MAPK_RevD_3	328	344	PF00069	0.416
DOC_PP1_RVXF_1	356	362	PF00149	0.387
DOC_PP1_RVXF_1	53	59	PF00149	0.334
DOC_PP1_RVXF_1	535	541	PF00149	0.407
DOC_PP1_RVXF_1	730	737	PF00149	0.513
DOC_PP2B_LxvP_1	463	466	PF13499	0.416
DOC_PP2B_LxvP_1	836	839	PF13499	0.401
DOC_PP4_FxxP_1	262	265	PF00568	0.334
DOC_PP4_FxxP_1	812	815	PF00568	0.495
DOC_PP4_FxxP_1	845	848	PF00568	0.424
DOC_USP7_MATH_1	263	267	PF00917	0.416
DOC_USP7_MATH_1	805	809	PF00917	0.451
DOC_USP7_MATH_1	825	829	PF00917	0.310
DOC_USP7_UBL2_3	283	287	PF12436	0.416
DOC_USP7_UBL2_3	33	37	PF12436	0.334
DOC_USP7_UBL2_3	51	55	PF12436	0.334
DOC_USP7_UBL2_3	652	656	PF12436	0.759
DOC_USP7_UBL2_3	664	668	PF12436	0.732
DOC_WW_Pin1_4	523	528	PF00397	0.334
DOC_WW_Pin1_4	576	581	PF00397	0.416
DOC_WW_Pin1_4	674	679	PF00397	0.627
DOC_WW_Pin1_4	78	83	PF00397	0.316
DOC_WW_Pin1_4	811	816	PF00397	0.493
DOC_WW_Pin1_4	844	849	PF00397	0.464
DOC_WW_Pin1_4	875	880	PF00397	0.608
LIG_14-3-3_CanoR_1	304	312	PF00244	0.334
LIG_14-3-3_CanoR_1	358	362	PF00244	0.323
LIG_14-3-3_CanoR_1	405	412	PF00244	0.407
LIG_14-3-3_CanoR_1	568	574	PF00244	0.422
LIG_14-3-3_CanoR_1	587	595	PF00244	0.416
LIG_14-3-3_CanoR_1	626	632	PF00244	0.600
LIG_14-3-3_CanoR_1	653	663	PF00244	0.742
LIG_14-3-3_CanoR_1	669	674	PF00244	0.674
LIG_14-3-3_CanoR_1	712	717	PF00244	0.631
LIG_14-3-3_CanoR_1	755	759	PF00244	0.409
LIG_14-3-3_CanoR_1	830	839	PF00244	0.467
LIG_Actin_WH2_2	274	292	PF00022	0.334
LIG_Actin_WH2_2	333	351	PF00022	0.366
LIG_APCC_ABBA_1	939	944	PF00400	0.486
LIG_BRCT_BRCA1_1	133	137	PF00533	0.416
LIG_BRCT_BRCA1_1	550	554	PF00533	0.427
LIG_eIF4E_1	350	356	PF01652	0.334
LIG_FHA_1	105	111	PF00498	0.323
LIG_FHA_1	283	289	PF00498	0.366
LIG_FHA_1	427	433	PF00498	0.468
LIG_FHA_1	524	530	PF00498	0.410
LIG_FHA_1	533	539	PF00498	0.339
LIG_FHA_1	543	549	PF00498	0.169
LIG_FHA_1	587	593	PF00498	0.416
LIG_FHA_1	755	761	PF00498	0.397
LIG_FHA_1	797	803	PF00498	0.560
LIG_FHA_1	831	837	PF00498	0.508
LIG_FHA_1	90	96	PF00498	0.337
LIG_FHA_2	405	411	PF00498	0.366
LIG_FHA_2	43	49	PF00498	0.368
LIG_FHA_2	556	562	PF00498	0.412
LIG_FHA_2	670	676	PF00498	0.744
LIG_LIR_Apic_2	843	848	PF02991	0.417
LIG_LIR_Gen_1	134	145	PF02991	0.340
LIG_LIR_Gen_1	360	369	PF02991	0.416
LIG_LIR_Gen_1	539	548	PF02991	0.376
LIG_LIR_Gen_1	558	565	PF02991	0.171
LIG_LIR_Gen_1	589	597	PF02991	0.391
LIG_LIR_Gen_1	691	701	PF02991	0.695
LIG_LIR_Gen_1	854	863	PF02991	0.441
LIG_LIR_Nem_3	109	114	PF02991	0.368
LIG_LIR_Nem_3	134	140	PF02991	0.340
LIG_LIR_Nem_3	143	149	PF02991	0.324
LIG_LIR_Nem_3	238	244	PF02991	0.334
LIG_LIR_Nem_3	360	364	PF02991	0.354
LIG_LIR_Nem_3	417	421	PF02991	0.316
LIG_LIR_Nem_3	445	449	PF02991	0.335
LIG_LIR_Nem_3	539	543	PF02991	0.360
LIG_LIR_Nem_3	551	557	PF02991	0.246
LIG_LIR_Nem_3	558	563	PF02991	0.169
LIG_LIR_Nem_3	589	594	PF02991	0.338
LIG_LIR_Nem_3	67	71	PF02991	0.407
LIG_LIR_Nem_3	691	697	PF02991	0.660
LIG_LIR_Nem_3	843	849	PF02991	0.449
LIG_LIR_Nem_3	854	860	PF02991	0.395
LIG_LIR_Nem_3	922	926	PF02991	0.512
LIG_LYPXL_yS_3	173	176	PF13949	0.351
LIG_MLH1_MIPbox_1	550	554	PF16413	0.427
LIG_NRBOX	162	168	PF00104	0.416
LIG_NRBOX	254	260	PF00104	0.416
LIG_NRBOX	696	702	PF00104	0.665
LIG_NRBOX	887	893	PF00104	0.514
LIG_PCNA_yPIPBox_3	304	316	PF02747	0.414
LIG_REV1ctd_RIR_1	551	559	PF16727	0.427
LIG_RPA_C_Fungi	400	412	PF08784	0.407
LIG_SH2_CRK	217	221	PF00017	0.416
LIG_SH2_CRK	244	248	PF00017	0.334
LIG_SH2_NCK_1	560	564	PF00017	0.416
LIG_SH2_NCK_1	822	826	PF00017	0.487
LIG_SH2_PTP2	350	353	PF00017	0.403
LIG_SH2_PTP2	449	452	PF00017	0.368
LIG_SH2_PTP2	923	926	PF00017	0.563
LIG_SH2_SRC	418	421	PF00017	0.295
LIG_SH2_SRC	449	452	PF00017	0.368
LIG_SH2_SRC	517	520	PF00017	0.334
LIG_SH2_SRC	560	563	PF00017	0.416
LIG_SH2_SRC	717	720	PF00017	0.546
LIG_SH2_SRC	822	825	PF00017	0.573
LIG_SH2_SRC	923	926	PF00017	0.510
LIG_SH2_STAP1	560	564	PF00017	0.368
LIG_SH2_STAT5	241	244	PF00017	0.334
LIG_SH2_STAT5	261	264	PF00017	0.139
LIG_SH2_STAT5	350	353	PF00017	0.351
LIG_SH2_STAT5	418	421	PF00017	0.295
LIG_SH2_STAT5	442	445	PF00017	0.344
LIG_SH2_STAT5	449	452	PF00017	0.319
LIG_SH2_STAT5	52	55	PF00017	0.334
LIG_SH2_STAT5	557	560	PF00017	0.468
LIG_SH2_STAT5	576	579	PF00017	0.408
LIG_SH2_STAT5	89	92	PF00017	0.334
LIG_SH2_STAT5	923	926	PF00017	0.510
LIG_SH2_STAT5	942	945	PF00017	0.226
LIG_SH3_2	609	614	PF14604	0.612
LIG_SH3_3	243	249	PF00018	0.334
LIG_SH3_3	359	365	PF00018	0.416
LIG_SH3_3	474	480	PF00018	0.416
LIG_SH3_3	603	609	PF00018	0.499
LIG_SH3_3	700	706	PF00018	0.584
LIG_SH3_3	836	842	PF00018	0.531
LIG_SH3_4	662	669	PF00018	0.562
LIG_SUMO_SIM_anti_2	136	143	PF11976	0.416
LIG_SUMO_SIM_anti_2	331	338	PF11976	0.389
LIG_SUMO_SIM_anti_2	434	440	PF11976	0.407
LIG_SUMO_SIM_anti_2	589	596	PF11976	0.387
LIG_SUMO_SIM_par_1	100	107	PF11976	0.369
LIG_SUMO_SIM_par_1	113	119	PF11976	0.362
LIG_SUMO_SIM_par_1	175	181	PF11976	0.351
LIG_SUMO_SIM_par_1	451	459	PF11976	0.416
LIG_SUMO_SIM_par_1	698	704	PF11976	0.716
LIG_SUMO_SIM_par_1	756	762	PF11976	0.407
LIG_SUMO_SIM_par_1	798	803	PF11976	0.474
LIG_SUMO_SIM_par_1	833	840	PF11976	0.419
LIG_TRAF2_2	706	711	PF00917	0.547
LIG_TYR_ITIM	259	264	PF00017	0.416
LIG_TYR_ITIM	348	353	PF00017	0.368
LIG_TYR_ITIM	416	421	PF00017	0.316
LIG_TYR_ITIM	921	926	PF00017	0.468
LIG_TYR_ITSM	556	563	PF00017	0.468
LIG_UBA3_1	163	172	PF00899	0.416
LIG_UBA3_1	274	283	PF00899	0.369
LIG_UBA3_1	569	578	PF00899	0.242
LIG_UBA3_1	724	732	PF00899	0.530
LIG_WRC_WIRS_1	336	341	PF05994	0.368
LIG_WRC_WIRS_1	550	555	PF05994	0.368
MOD_CDK_SPxxK_3	78	85	PF00069	0.316
MOD_CDK_SPxxK_3	875	882	PF00069	0.659
MOD_CK1_1	118	124	PF00069	0.403
MOD_CK1_1	210	216	PF00069	0.416
MOD_CK1_1	303	309	PF00069	0.468
MOD_CK1_1	338	344	PF00069	0.416
MOD_CK1_1	387	393	PF00069	0.343
MOD_CK1_1	42	48	PF00069	0.416
MOD_CK1_1	539	545	PF00069	0.338
MOD_CK1_1	677	683	PF00069	0.647
MOD_CK1_1	704	710	PF00069	0.617
MOD_CK1_1	737	743	PF00069	0.542
MOD_CK1_1	78	84	PF00069	0.416
MOD_CK1_1	814	820	PF00069	0.542
MOD_CK1_1	837	843	PF00069	0.480
MOD_CK2_1	652	658	PF00069	0.778
MOD_CK2_1	712	718	PF00069	0.641
MOD_CK2_1	930	936	PF00069	0.533
MOD_Cter_Amidation	650	653	PF01082	0.759
MOD_GlcNHglycan	205	208	PF01048	0.312
MOD_GlcNHglycan	305	308	PF01048	0.334
MOD_GlcNHglycan	658	661	PF01048	0.790
MOD_GlcNHglycan	82	85	PF01048	0.416
MOD_GlcNHglycan	827	830	PF01048	0.601
MOD_GlcNHglycan	879	882	PF01048	0.556
MOD_GlcNHglycan	903	906	PF01048	0.494
MOD_GlcNHglycan	932	935	PF01048	0.570
MOD_GSK3_1	120	127	PF00069	0.380
MOD_GSK3_1	203	210	PF00069	0.242
MOD_GSK3_1	334	341	PF00069	0.334
MOD_GSK3_1	38	45	PF00069	0.369
MOD_GSK3_1	427	434	PF00069	0.416
MOD_GSK3_1	532	539	PF00069	0.431
MOD_GSK3_1	544	551	PF00069	0.291
MOD_GSK3_1	652	659	PF00069	0.779
MOD_GSK3_1	674	681	PF00069	0.733
MOD_GSK3_1	785	792	PF00069	0.573
MOD_GSK3_1	830	837	PF00069	0.533
MOD_GSK3_1	840	847	PF00069	0.364
MOD_GSK3_1	861	868	PF00069	0.442
MOD_GSK3_1	97	104	PF00069	0.403
MOD_N-GLC_1	403	408	PF02516	0.424
MOD_N-GLC_1	647	652	PF02516	0.755
MOD_N-GLC_1	737	742	PF02516	0.564
MOD_N-GLC_1	855	860	PF02516	0.585
MOD_NEK2_1	103	108	PF00069	0.334
MOD_NEK2_1	120	125	PF00069	0.218
MOD_NEK2_1	150	155	PF00069	0.403
MOD_NEK2_1	189	194	PF00069	0.353
MOD_NEK2_1	335	340	PF00069	0.468
MOD_NEK2_1	38	43	PF00069	0.369
MOD_NEK2_1	427	432	PF00069	0.380
MOD_NEK2_1	538	543	PF00069	0.403
MOD_NEK2_1	57	62	PF00069	0.334
MOD_NEK2_1	627	632	PF00069	0.599
MOD_NEK2_1	701	706	PF00069	0.607
MOD_NEK2_1	725	730	PF00069	0.483
MOD_NEK2_1	743	748	PF00069	0.506
MOD_NEK2_1	90	95	PF00069	0.380
MOD_NEK2_2	805	810	PF00069	0.488
MOD_PIKK_1	190	196	PF00454	0.345
MOD_PIKK_1	291	297	PF00454	0.352
MOD_PIKK_1	298	304	PF00454	0.386
MOD_PIKK_1	532	538	PF00454	0.389
MOD_PIKK_1	542	548	PF00454	0.274
MOD_PIKK_1	704	710	PF00454	0.617
MOD_PIKK_1	75	81	PF00454	0.407
MOD_PK_1	712	718	PF00069	0.582
MOD_PKA_1	14	20	PF00069	0.489
MOD_PKA_1	343	349	PF00069	0.351
MOD_PKA_1	495	501	PF00069	0.386
MOD_PKA_1	652	658	PF00069	0.778
MOD_PKA_1	669	675	PF00069	0.594
MOD_PKA_2	14	20	PF00069	0.571
MOD_PKA_2	298	304	PF00069	0.349
MOD_PKA_2	343	349	PF00069	0.424
MOD_PKA_2	357	363	PF00069	0.397
MOD_PKA_2	404	410	PF00069	0.407
MOD_PKA_2	586	592	PF00069	0.416
MOD_PKA_2	652	658	PF00069	0.773
MOD_PKA_2	669	675	PF00069	0.601
MOD_PKA_2	754	760	PF00069	0.386
MOD_Plk_1	150	156	PF00069	0.416
MOD_Plk_1	22	28	PF00069	0.468
MOD_Plk_1	387	393	PF00069	0.316
MOD_Plk_1	39	45	PF00069	0.188
MOD_Plk_1	701	707	PF00069	0.656
MOD_Plk_1	737	743	PF00069	0.559
MOD_Plk_1	855	861	PF00069	0.470
MOD_Plk_1	943	949	PF00069	0.520
MOD_Plk_2-3	113	119	PF00069	0.309
MOD_Plk_4	106	112	PF00069	0.334
MOD_Plk_4	162	168	PF00069	0.363
MOD_Plk_4	178	184	PF00069	0.334
MOD_Plk_4	335	341	PF00069	0.368
MOD_Plk_4	351	357	PF00069	0.428
MOD_Plk_4	427	433	PF00069	0.412
MOD_Plk_4	452	458	PF00069	0.332
MOD_Plk_4	539	545	PF00069	0.358
MOD_Plk_4	549	555	PF00069	0.349
MOD_Plk_4	616	622	PF00069	0.593
MOD_Plk_4	754	760	PF00069	0.477
MOD_Plk_4	841	847	PF00069	0.504
MOD_Plk_4	90	96	PF00069	0.334
MOD_Plk_4	943	949	PF00069	0.429
MOD_ProDKin_1	523	529	PF00069	0.334
MOD_ProDKin_1	576	582	PF00069	0.416
MOD_ProDKin_1	674	680	PF00069	0.628
MOD_ProDKin_1	78	84	PF00069	0.316
MOD_ProDKin_1	811	817	PF00069	0.492
MOD_ProDKin_1	844	850	PF00069	0.479
MOD_ProDKin_1	875	881	PF00069	0.607
MOD_SUMO_rev_2	424	430	PF00179	0.242
TRG_DiLeu_BaEn_1	331	336	PF01217	0.468
TRG_DiLeu_BaEn_1	590	595	PF01217	0.316
TRG_DiLeu_BaEn_1	696	701	PF01217	0.665
TRG_DiLeu_BaEn_1	72	77	PF01217	0.334
TRG_DiLeu_BaEn_1	98	103	PF01217	0.368
TRG_DiLeu_BaEn_2	935	941	PF01217	0.548
TRG_DiLeu_BaLyEn_6	254	259	PF01217	0.334
TRG_ENDOCYTIC_2	111	114	PF00928	0.334
TRG_ENDOCYTIC_2	173	176	PF00928	0.384
TRG_ENDOCYTIC_2	217	220	PF00928	0.416
TRG_ENDOCYTIC_2	243	246	PF00928	0.334
TRG_ENDOCYTIC_2	261	264	PF00928	0.334
TRG_ENDOCYTIC_2	350	353	PF00928	0.334
TRG_ENDOCYTIC_2	418	421	PF00928	0.316
TRG_ENDOCYTIC_2	449	452	PF00928	0.368
TRG_ENDOCYTIC_2	560	563	PF00928	0.351
TRG_ENDOCYTIC_2	694	697	PF00928	0.702
TRG_ENDOCYTIC_2	923	926	PF00928	0.462
TRG_ER_diArg_1	13	15	PF00400	0.538
TRG_ER_diArg_1	271	274	PF00400	0.468
TRG_ER_diArg_1	669	671	PF00400	0.550
TRG_ER_diArg_1	721	723	PF00400	0.546
TRG_NES_CRM1_1	409	424	PF08389	0.337
TRG_NES_CRM1_1	467	479	PF08389	0.416
TRG_NES_CRM1_1	502	514	PF08389	0.416
TRG_NES_CRM1_1	696	709	PF08389	0.655
TRG_NLS_Bipartite_1	484	499	PF00514	0.366
TRG_NLS_Bipartite_1	652	672	PF00514	0.571
TRG_NLS_MonoExtC_3	391	397	PF00514	0.416
TRG_NLS_MonoExtC_3	651	656	PF00514	0.742
TRG_NLS_MonoExtN_4	652	657	PF00514	0.803
TRG_Pf-PMV_PEXEL_1	218	222	PF00026	0.404
TRG_Pf-PMV_PEXEL_1	230	234	PF00026	0.334
TRG_Pf-PMV_PEXEL_1	722	726	PF00026	0.529

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P707	Leptomonas seymouri	26%	100%
A0A0N1I3J7	Leptomonas seymouri	23%	87%
A0A0N1PA13	Leptomonas seymouri	75%	100%
A0A0S4IMH5	Bodo saltans	33%	100%
A0A1X0NLY4	Trypanosomatidae	45%	99%
A0A3Q8IHK1	Leishmania donovani	26%	100%
A0A3S7WPR4	Leishmania donovani	95%	100%
A0A422NT90	Trypanosoma rangeli	46%	100%
A4H4U8	Leishmania braziliensis	87%	100%
A4HBC0	Leishmania braziliensis	26%	100%
A4HT27	Leishmania infantum	95%	100%
A4IAG8	Leishmania infantum	26%	100%
C9ZLS4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9AL15	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B5J2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
O94973	Homo sapiens	35%	100%
P17427	Mus musculus	32%	100%
P18484	Rattus norvegicus	32%	100%
P38065	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	94%
P91926	Drosophila melanogaster	31%	100%
Q0VCK5	Bos taurus	31%	100%
Q12028	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
Q29N38	Drosophila pseudoobscura pseudoobscura	31%	100%
Q4Q2E4	Leishmania major	26%	100%
Q7QG73	Anopheles gambiae	31%	100%
Q8LPK4	Arabidopsis thaliana	35%	95%
Q8LPL6	Arabidopsis thaliana	34%	95%
Q99128	Ustilago maydis (strain 521 / FGSC 9021)	27%	100%
Q9C0W7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%