Putative ATP-dependent DEAD/H RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase DBP2B, putative

Species:

Leishmania major

UniProt:

Q4QIQ9_LEIMA

TriTrypDb:

LmjF.07.0340 , LMJLV39_070009400 , LMJLV39_070009500 , LMJSD75_070009600 , LMJSD75_070009700

Length:

592

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005654	nucleoplasm	2	2
GO:0005730	nucleolus	5	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3
GO:1990904	ribonucleoprotein complex	2	2
GO:0016020	membrane	2	1

Expansion

Sequence features

Q4QIQ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIQ9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	2
GO:0003724	RNA helicase activity	3	12
GO:0003743	translation initiation factor activity	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	11
GO:0008186	ATP-dependent activity, acting on RNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	3	7	PF00656	0.695
CLV_C14_Caspase3-7	496	500	PF00656	0.388
CLV_NRD_NRD_1	238	240	PF00675	0.276
CLV_NRD_NRD_1	314	316	PF00675	0.276
CLV_NRD_NRD_1	437	439	PF00675	0.290
CLV_PCSK_SKI1_1	105	109	PF00082	0.587
CLV_PCSK_SKI1_1	239	243	PF00082	0.276
CLV_PCSK_SKI1_1	442	446	PF00082	0.301
CLV_Separin_Metazoa	383	387	PF03568	0.564
DEG_APCC_DBOX_1	238	246	PF00400	0.476
DEG_SCF_FBW7_1	168	173	PF00400	0.385
DOC_CKS1_1	274	279	PF01111	0.476
DOC_CYCLIN_RxL_1	386	399	PF00134	0.479
DOC_MAPK_gen_1	264	274	PF00069	0.501
DOC_MAPK_gen_1	322	330	PF00069	0.476
DOC_MAPK_gen_1	412	421	PF00069	0.564
DOC_MAPK_gen_1	436	446	PF00069	0.488
DOC_MAPK_gen_1	502	512	PF00069	0.360
DOC_MAPK_MEF2A_6	139	147	PF00069	0.431
DOC_MAPK_MEF2A_6	267	274	PF00069	0.476
DOC_MAPK_MEF2A_6	347	354	PF00069	0.391
DOC_MAPK_MEF2A_6	505	512	PF00069	0.365
DOC_MAPK_NFAT4_5	505	513	PF00069	0.370
DOC_PP1_RVXF_1	390	397	PF00149	0.476
DOC_PP1_RVXF_1	95	101	PF00149	0.510
DOC_PP2B_LxvP_1	150	153	PF13499	0.416
DOC_PP4_FxxP_1	112	115	PF00568	0.566
DOC_PP4_FxxP_1	165	168	PF00568	0.571
DOC_PP4_FxxP_1	199	202	PF00568	0.476
DOC_USP7_MATH_1	170	174	PF00917	0.476
DOC_USP7_MATH_1	498	502	PF00917	0.595
DOC_WW_Pin1_4	166	171	PF00397	0.463
DOC_WW_Pin1_4	254	259	PF00397	0.515
DOC_WW_Pin1_4	273	278	PF00397	0.371
DOC_WW_Pin1_4	516	521	PF00397	0.388
DOC_WW_Pin1_4	587	592	PF00397	0.580
LIG_14-3-3_CanoR_1	293	297	PF00244	0.476
LIG_14-3-3_CanoR_1	325	329	PF00244	0.476
LIG_14-3-3_CanoR_1	415	419	PF00244	0.564
LIG_Actin_WH2_2	277	295	PF00022	0.476
LIG_ActinCP_TwfCPI_2	112	119	PF01115	0.596
LIG_APCC_ABBA_1	133	138	PF00400	0.413
LIG_APCC_ABBA_1	419	424	PF00400	0.476
LIG_BIR_II_1	1	5	PF00653	0.700
LIG_BRCT_BRCA1_1	585	589	PF00533	0.587
LIG_FHA_1	225	231	PF00498	0.476
LIG_FHA_1	248	254	PF00498	0.518
LIG_FHA_1	287	293	PF00498	0.480
LIG_FHA_2	296	302	PF00498	0.575
LIG_FHA_2	501	507	PF00498	0.494
LIG_LIR_Apic_2	162	168	PF02991	0.460
LIG_LIR_Apic_2	196	202	PF02991	0.476
LIG_LIR_Gen_1	146	155	PF02991	0.501
LIG_LIR_Gen_1	295	302	PF02991	0.468
LIG_LIR_Gen_1	348	354	PF02991	0.381
LIG_LIR_Gen_1	490	498	PF02991	0.476
LIG_LIR_Gen_1	99	107	PF02991	0.465
LIG_LIR_Nem_3	108	113	PF02991	0.482
LIG_LIR_Nem_3	146	150	PF02991	0.496
LIG_LIR_Nem_3	173	179	PF02991	0.484
LIG_LIR_Nem_3	295	299	PF02991	0.468
LIG_LIR_Nem_3	348	352	PF02991	0.379
LIG_LIR_Nem_3	490	495	PF02991	0.512
LIG_LIR_Nem_3	586	592	PF02991	0.579
LIG_LIR_Nem_3	99	103	PF02991	0.447
LIG_MYND_1	211	215	PF01753	0.538
LIG_NRBOX	279	285	PF00104	0.488
LIG_NRBOX	506	512	PF00104	0.361
LIG_Pex14_2	330	334	PF04695	0.476
LIG_Pex14_2	345	349	PF04695	0.411
LIG_SH2_CRK	466	470	PF00017	0.564
LIG_SH2_CRK	492	496	PF00017	0.341
LIG_SH2_CRK	573	577	PF00017	0.647
LIG_SH2_STAT3	113	116	PF00017	0.486
LIG_SH2_STAT5	296	299	PF00017	0.488
LIG_SH2_STAT5	432	435	PF00017	0.485
LIG_SH2_STAT5	475	478	PF00017	0.476
LIG_SH3_2	580	585	PF14604	0.507
LIG_SH3_3	112	118	PF00018	0.584
LIG_SH3_3	137	143	PF00018	0.413
LIG_SH3_3	171	177	PF00018	0.564
LIG_SH3_3	209	215	PF00018	0.489
LIG_SH3_3	220	226	PF00018	0.455
LIG_SH3_3	255	261	PF00018	0.488
LIG_SH3_3	577	583	PF00018	0.517
LIG_SUMO_SIM_anti_2	459	464	PF11976	0.505
LIG_SUMO_SIM_anti_2	506	512	PF11976	0.361
LIG_SUMO_SIM_par_1	175	182	PF11976	0.478
LIG_SUMO_SIM_par_1	279	286	PF11976	0.485
LIG_TRAF2_1	120	123	PF00917	0.592
LIG_TRAF2_1	514	517	PF00917	0.404
LIG_TRAF2_2	212	217	PF00917	0.564
LIG_TYR_ITIM	294	299	PF00017	0.488
LIG_UBA3_1	507	515	PF00899	0.376
LIG_WW_3	582	586	PF00397	0.507
MOD_CDK_SPK_2	254	259	PF00069	0.518
MOD_CDK_SPxK_1	273	279	PF00069	0.476
MOD_CK1_1	193	199	PF00069	0.467
MOD_CK1_1	247	253	PF00069	0.507
MOD_CK1_1	493	499	PF00069	0.365
MOD_CK2_1	117	123	PF00069	0.470
MOD_CK2_1	295	301	PF00069	0.573
MOD_GlcNHglycan	13	16	PF01048	0.646
MOD_GlcNHglycan	192	195	PF01048	0.267
MOD_GlcNHglycan	330	333	PF01048	0.276
MOD_GlcNHglycan	496	499	PF01048	0.572
MOD_GlcNHglycan	60	63	PF01048	0.692
MOD_GSK3_1	166	173	PF00069	0.339
MOD_GSK3_1	240	247	PF00069	0.511
MOD_GSK3_1	316	323	PF00069	0.484
MOD_GSK3_1	324	331	PF00069	0.442
MOD_GSK3_1	490	497	PF00069	0.501
MOD_GSK3_1	583	590	PF00069	0.578
MOD_N-GLC_1	286	291	PF02516	0.364
MOD_NEK2_1	283	288	PF00069	0.484
MOD_NEK2_1	292	297	PF00069	0.453
MOD_NEK2_1	328	333	PF00069	0.472
MOD_NEK2_1	341	346	PF00069	0.363
MOD_NEK2_1	396	401	PF00069	0.477
MOD_NEK2_1	414	419	PF00069	0.488
MOD_PIKK_1	105	111	PF00454	0.494
MOD_PIKK_1	316	322	PF00454	0.488
MOD_PK_1	129	135	PF00069	0.550
MOD_PK_1	244	250	PF00069	0.518
MOD_PKA_2	292	298	PF00069	0.487
MOD_PKA_2	324	330	PF00069	0.476
MOD_PKA_2	414	420	PF00069	0.564
MOD_Plk_1	129	135	PF00069	0.550
MOD_Plk_4	123	129	PF00069	0.572
MOD_Plk_4	244	250	PF00069	0.564
MOD_Plk_4	292	298	PF00069	0.501
MOD_Plk_4	324	330	PF00069	0.467
MOD_Plk_4	414	420	PF00069	0.538
MOD_Plk_4	490	496	PF00069	0.517
MOD_ProDKin_1	166	172	PF00069	0.367
MOD_ProDKin_1	254	260	PF00069	0.515
MOD_ProDKin_1	273	279	PF00069	0.371
MOD_ProDKin_1	516	522	PF00069	0.381
MOD_SUMO_for_1	514	517	PF00179	0.404
MOD_SUMO_rev_2	373	381	PF00179	0.540
TRG_DiLeu_BaEn_1	146	151	PF01217	0.512
TRG_DiLeu_BaEn_1	441	446	PF01217	0.564
TRG_DiLeu_BaLyEn_6	276	281	PF01217	0.476
TRG_ENDOCYTIC_2	296	299	PF00928	0.488
TRG_ENDOCYTIC_2	492	495	PF00928	0.378
TRG_NES_CRM1_1	459	474	PF08389	0.557
TRG_Pf-PMV_PEXEL_1	228	233	PF00026	0.276
TRG_Pf-PMV_PEXEL_1	412	416	PF00026	0.364
TRG_Pf-PMV_PEXEL_1	505	509	PF00026	0.367

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4X4	Leptomonas seymouri	30%	85%
A0A0N0P7D9	Leptomonas seymouri	88%	100%
A0A0N0P7N8	Leptomonas seymouri	50%	100%
A0A0N0P942	Leptomonas seymouri	33%	68%
A0A0N1I5R1	Leptomonas seymouri	25%	75%
A0A0N1I7N1	Leptomonas seymouri	38%	95%
A0A0N1PDE7	Leptomonas seymouri	32%	100%
A0A0N1PDY8	Leptomonas seymouri	37%	100%
A0A0S4IKX9	Bodo saltans	27%	78%
A0A0S4ITZ4	Bodo saltans	72%	100%
A0A0S4IX79	Bodo saltans	28%	81%
A0A0S4J192	Bodo saltans	43%	99%
A0A0S4J214	Bodo saltans	25%	100%
A0A0S4JCH6	Bodo saltans	37%	100%
A0A0S4JSZ9	Bodo saltans	32%	98%
A0A0S4JT14	Bodo saltans	51%	100%
A0A0S4KKU4	Bodo saltans	30%	85%
A0A1X0NP86	Trypanosomatidae	75%	100%
A0A1X0NQS6	Trypanosomatidae	36%	100%
A0A1X0P2M8	Trypanosomatidae	32%	92%
A0A1X0P5C7	Trypanosomatidae	39%	75%
A0A1X0P6S6	Trypanosomatidae	42%	90%
A0A1X0P8K3	Trypanosomatidae	49%	97%
A0A3Q8IC45	Leishmania donovani	29%	100%
A0A3Q8ID91	Leishmania donovani	34%	100%
A0A3Q8IEU7	Leishmania donovani	30%	100%
A0A3Q8IF94	Leishmania donovani	42%	96%
A0A3Q8IQY6	Leishmania donovani	51%	100%
A0A3R7K6G7	Trypanosoma rangeli	74%	100%
A0A3R7KAR1	Trypanosoma rangeli	37%	100%
A0A3R7KKL1	Trypanosoma rangeli	29%	83%
A0A3R7N322	Trypanosoma rangeli	39%	98%
A0A3R7NGQ1	Trypanosoma rangeli	33%	95%
A0A3R7RJV1	Trypanosoma rangeli	31%	100%
A0A3S5H4X0	Leishmania donovani	34%	100%
A0A3S5H5X3	Leishmania donovani	100%	100%
A0A3S7WQ33	Leishmania donovani	35%	86%
A0A3S7WR01	Leishmania donovani	24%	76%
A0A3S7X579	Leishmania donovani	32%	100%
A0A3S7XAT8	Leishmania donovani	35%	100%
A0A422MXD2	Trypanosoma rangeli	40%	74%
A0A422N502	Trypanosoma rangeli	45%	100%
A0A422NDK5	Trypanosoma rangeli	33%	100%
A0A422NRX1	Trypanosoma rangeli	36%	79%
A0A422NYD5	Trypanosoma rangeli	33%	89%
A0A422P419	Trypanosoma rangeli	25%	100%
A1A4H6	Bos taurus	37%	77%
A1C5V3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	41%	100%
A1C6C4	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	52%	100%
A1CH78	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	40%	87%
A1CHL3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	35%	74%
A1CX72	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	36%	74%
A1CXK7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	43%	88%
A1DG51	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	41%	100%
A1DGZ7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	49%	100%
A2QC74	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	47%	100%
A2QFL3	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	40%	100%
A2QI25	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	44%	87%
A2QIL2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	73%
A3LNL1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	35%	100%
A3LQ01	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	39%	91%
A3LQ55	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	39%	68%
A3LQW7	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	51%	100%
A3LRW2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	44%	100%
A4H4Y0	Leishmania braziliensis	98%	98%
A4H575	Leishmania braziliensis	35%	68%
A4H5Z5	Leishmania braziliensis	23%	82%
A4HC04	Leishmania braziliensis	29%	100%
A4HGR1	Leishmania braziliensis	35%	100%
A4HK20	Leishmania braziliensis	42%	98%
A4HK38	Leishmania braziliensis	31%	100%
A4HKL3	Leishmania braziliensis	29%	77%
A4HMX7	Leishmania braziliensis	40%	69%
A4HP49	Leishmania braziliensis	35%	100%
A4HP82	Leishmania braziliensis	51%	100%
A4HRK0	Leishmania infantum	34%	100%
A4HT33	Leishmania infantum	100%	100%
A4HTF8	Leishmania infantum	35%	86%
A4HUC1	Leishmania infantum	24%	76%
A4HZF8	Leishmania infantum	29%	100%
A4I3T6	Leishmania infantum	34%	100%
A4I7K4	Leishmania infantum	42%	96%
A4I7M5	Leishmania infantum	32%	100%
A4IAT7	Leishmania infantum	30%	100%
A4IDF6	Leishmania infantum	35%	100%
A4IDI7	Leishmania infantum	47%	100%
A4QSS5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	50%	100%
A4RHF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	42%	88%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	38%	88%
A5A6J2	Pan troglodytes	47%	96%
A5DDF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	38%	69%
A5DF03	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	100%
A5DL80	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	51%	100%
A5DQF1	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	39%	100%
A5DQS0	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	42%	93%
A5DS77	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	53%	100%
A5DU73	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	36%	99%
A5DZE6	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	42%	89%
A5E1W4	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	42%	100%
A6QRQ7	Ajellomyces capsulatus (strain NAm1 / WU24)	37%	100%
A6QXC1	Ajellomyces capsulatus (strain NAm1 / WU24)	40%	100%
A6R3L3	Ajellomyces capsulatus (strain NAm1 / WU24)	42%	85%
A6RGE3	Ajellomyces capsulatus (strain NAm1 / WU24)	48%	100%
A6RJA2	Botryotinia fuckeliana (strain B05.10)	38%	76%
A6SCT6	Botryotinia fuckeliana (strain B05.10)	43%	100%
A6SEH9	Botryotinia fuckeliana (strain B05.10)	43%	87%
A6SFW7	Botryotinia fuckeliana (strain B05.10)	50%	100%
A6ZLH6	Saccharomyces cerevisiae (strain YJM789)	30%	70%
A6ZP47	Saccharomyces cerevisiae (strain YJM789)	41%	98%
A6ZRX0	Saccharomyces cerevisiae (strain YJM789)	47%	100%
A6ZWD3	Saccharomyces cerevisiae (strain YJM789)	40%	96%
A7E449	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	50%	100%
A7EGG4	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	37%	73%
A7EJY3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	43%	87%
A7EML8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	100%
A7EYW0	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	44%	99%
A7TJK8	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	33%	68%
A7TKR8	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	38%	91%
A7TTT5	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	46%	100%
C8V8H4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	89%
C9ZPX8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	94%
C9ZUS0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	74%	100%
C9ZZ43	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	80%
D0A0A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	96%
D0A378	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D0A4H6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	99%
D0A872	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A9S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0PV95	Caenorhabditis elegans	39%	84%
E9AEL4	Leishmania major	30%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AL45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9AM86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	86%
E9AN20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	80%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9ASZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B2G1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	95%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B5S5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
G0SFM2	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	51%	100%
O00571	Homo sapiens	37%	89%
O01836	Caenorhabditis elegans	36%	82%
O13370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	93%
O15523	Homo sapiens	39%	90%
O22907	Arabidopsis thaliana	42%	78%
O62591	Leishmania major	34%	100%
P06634	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	98%
P09052	Drosophila melanogaster	41%	90%
P0CQ74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	40%	93%
P0CQ75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	40%	93%
P0CQ76	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	51%	100%
P0CQ77	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	51%	100%
P0CQ78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	42%	98%
P0CQ79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	42%	98%
P0CQ88	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	36%	80%
P0CQ89	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	36%	80%
P16381	Mus musculus	41%	90%
P17844	Homo sapiens	47%	96%
P19109	Drosophila melanogaster	48%	82%
P21372	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	70%
P21693	Escherichia coli (strain K12)	37%	100%
P23394	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
P24346	Xenopus laevis	39%	85%
P24782	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	100%
P24783	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	100%
P24784	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	96%
P34689	Caenorhabditis elegans	35%	78%
P46942	Nicotiana sylvestris	49%	98%
P93008	Arabidopsis thaliana	40%	81%
Q0CL13	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	41%	100%
Q0CLJ6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	44%	88%
Q0CLX0	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	34%	76%
Q0DB53	Oryza sativa subsp. japonica	38%	98%
Q0E2Z7	Oryza sativa subsp. japonica	33%	100%
Q0E3X4	Oryza sativa subsp. japonica	40%	94%
Q0UWA6	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	40%	85%
Q0UWC8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	37%	79%
Q0UY62	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	45%	100%
Q10202	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
Q10MH8	Oryza sativa subsp. japonica	43%	77%
Q1DJF0	Coccidioides immitis (strain RS)	41%	89%
Q1DMX8	Coccidioides immitis (strain RS)	34%	72%
Q1DP69	Coccidioides immitis (strain RS)	49%	100%
Q1DZK8	Coccidioides immitis (strain RS)	41%	100%
Q25225	Leishmania braziliensis	34%	100%
Q26696	Trypanosoma brucei brucei	47%	100%
Q2GUI4	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	41%	100%
Q2H720	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	48%	100%
Q2HBE7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	44%	86%
Q2HEB0	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	36%	84%
Q2R1M8	Oryza sativa subsp. japonica	41%	95%
Q2U070	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	50%	100%
Q2UGK3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	44%	88%
Q2UH00	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	74%
Q2UMH8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	41%	100%
Q3EBD3	Arabidopsis thaliana	34%	100%
Q3MSQ8	Pelophylax lessonae	39%	82%
Q4I7F9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	37%	82%
Q4I7K4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	42%	88%
Q4IF76	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	51%	100%
Q4IJH1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	42%	100%
Q4JG17	Penaeus vannamei	39%	84%
Q4P733	Ustilago maydis (strain 521 / FGSC 9021)	42%	88%
Q4PDT1	Ustilago maydis (strain 521 / FGSC 9021)	43%	100%
Q4PHU9	Ustilago maydis (strain 521 / FGSC 9021)	50%	100%
Q4Q1K8	Leishmania major	52%	100%
Q4Q1N9	Leishmania major	35%	100%
Q4Q5M6	Leishmania major	33%	100%
Q4Q5P5	Leishmania major	40%	100%
Q4Q858	Leishmania major	35%	100%
Q4QC38	Leishmania major	29%	100%
Q4QIG1	Leishmania major	35%	86%
Q4R5S7	Macaca fascicularis	40%	82%
Q4R6M5	Macaca fascicularis	47%	96%
Q4WH83	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	42%	100%
Q4WP13	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	44%	88%
Q4WPE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	74%
Q4X195	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	48%	100%
Q501J6	Mus musculus	43%	91%
Q53RK8	Oryza sativa subsp. japonica	40%	80%
Q54CE0	Dictyostelium discoideum	51%	75%
Q54KG1	Dictyostelium discoideum	36%	88%
Q54QS3	Dictyostelium discoideum	37%	83%
Q54Y81	Dictyostelium discoideum	35%	71%
Q59LU0	Candida albicans (strain SC5314 / ATCC MYA-2876)	50%	100%
Q59W52	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	100%
Q5A4E2	Candida albicans (strain SC5314 / ATCC MYA-2876)	41%	88%
Q5ADL0	Candida albicans (strain SC5314 / ATCC MYA-2876)	39%	67%
Q5APT8	Candida albicans (strain SC5314 / ATCC MYA-2876)	43%	100%
Q5AWA6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	42%	100%
Q5B0J9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	51%	100%
Q5BCU6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	76%
Q5JKF2	Oryza sativa subsp. japonica	53%	75%
Q5N7W4	Oryza sativa subsp. japonica	48%	89%
Q5QMN3	Oryza sativa subsp. japonica	53%	100%
Q5R4I9	Pongo abelii	47%	96%
Q5RC67	Pongo abelii	42%	72%
Q5RF43	Pongo abelii	41%	90%
Q5VQL1	Oryza sativa subsp. japonica	48%	84%
Q5W5U4	Bos taurus	40%	81%
Q5Z6G5	Oryza sativa subsp. japonica	41%	96%
Q61496	Mus musculus	40%	84%
Q61656	Mus musculus	47%	96%
Q62095	Mus musculus	39%	90%
Q62167	Mus musculus	38%	89%
Q64060	Rattus norvegicus	35%	83%
Q6BLU9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	35%	100%
Q6BU54	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	36%	94%
Q6BY27	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	50%	100%
Q6BZ77	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	43%	100%
Q6C024	Yarrowia lipolytica (strain CLIB 122 / E 150)	36%	100%
Q6C4D4	Yarrowia lipolytica (strain CLIB 122 / E 150)	50%	100%
Q6C9P3	Yarrowia lipolytica (strain CLIB 122 / E 150)	46%	100%
Q6CB69	Yarrowia lipolytica (strain CLIB 122 / E 150)	42%	96%
Q6CIV2	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	47%	100%
Q6CKI1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	34%	73%
Q6CLR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	41%	94%
Q6CT46	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	45%	100%
Q6CT49	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	100%
Q6FLF3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	48%	100%
Q6FML5	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	73%
Q6FP38	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	40%	98%
Q6GVM6	Pan troglodytes	40%	90%
Q6GWX0	Sus scrofa	40%	82%
Q6Z4K6	Oryza sativa subsp. japonica	43%	93%
Q754U8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	69%
Q755N4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	48%	100%
Q75B50	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	39%	95%
Q75HJ0	Oryza sativa subsp. japonica	43%	93%
Q7RY59	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	100%
Q7S5R1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	96%
Q7SBC6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	50%	100%
Q7SEL0	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	36%	81%
Q84W89	Arabidopsis thaliana	42%	94%
Q86TM3	Homo sapiens	38%	94%
Q8GY84	Arabidopsis thaliana	34%	100%
Q8H136	Arabidopsis thaliana	50%	96%
Q8LA13	Arabidopsis thaliana	41%	97%
Q8SRB2	Encephalitozoon cuniculi (strain GB-M1)	42%	100%
Q8TFK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	41%	96%
Q8W4R3	Arabidopsis thaliana	53%	100%
Q91372	Xenopus laevis	39%	85%
Q91VN6	Mus musculus	39%	95%
Q921N6	Mus musculus	36%	78%
Q92841	Homo sapiens	43%	81%
Q96GQ7	Homo sapiens	37%	74%
Q9BUQ8	Homo sapiens	42%	72%
Q9C718	Arabidopsis thaliana	51%	100%
Q9LU46	Arabidopsis thaliana	38%	100%
Q9LYJ9	Arabidopsis thaliana	48%	92%
Q9M2F9	Arabidopsis thaliana	39%	92%
Q9NQI0	Homo sapiens	40%	82%
Q9NXZ2	Homo sapiens	40%	91%
Q9P6U9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	86%
Q9SZB4	Arabidopsis thaliana	38%	100%
Q9UJV9	Homo sapiens	39%	95%
Q9V3C0	Drosophila melanogaster	37%	96%
Q9Y7C4	Candida albicans (strain SC5314 / ATCC MYA-2876)	32%	100%
Q9Y7T7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	89%
V5AST3	Trypanosoma cruzi	74%	100%
V5BAS2	Trypanosoma cruzi	31%	100%
V5BEY7	Trypanosoma cruzi	33%	96%
V5BGF4	Trypanosoma cruzi	50%	100%
V5BL56	Trypanosoma cruzi	38%	100%
V5BS80	Trypanosoma cruzi	42%	94%