Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIQ4_LEIMA

TriTrypDb:

LmjF.07.0390 , LMJLV39_070010000 , LMJSD75_070010200

Length:

929

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIQ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIQ4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	479	483	PF00656	0.624
CLV_C14_Caspase3-7	508	512	PF00656	0.558
CLV_C14_Caspase3-7	73	77	PF00656	0.566
CLV_C14_Caspase3-7	892	896	PF00656	0.534
CLV_NRD_NRD_1	38	40	PF00675	0.571
CLV_NRD_NRD_1	497	499	PF00675	0.522
CLV_NRD_NRD_1	560	562	PF00675	0.551
CLV_NRD_NRD_1	816	818	PF00675	0.525
CLV_NRD_NRD_1	888	890	PF00675	0.581
CLV_PCSK_FUR_1	558	562	PF00082	0.470
CLV_PCSK_KEX2_1	38	40	PF00082	0.571
CLV_PCSK_KEX2_1	497	499	PF00082	0.522
CLV_PCSK_KEX2_1	560	562	PF00082	0.551
CLV_PCSK_KEX2_1	637	639	PF00082	0.742
CLV_PCSK_KEX2_1	816	818	PF00082	0.606
CLV_PCSK_KEX2_1	821	823	PF00082	0.565
CLV_PCSK_KEX2_1	888	890	PF00082	0.581
CLV_PCSK_PC1ET2_1	637	639	PF00082	0.639
CLV_PCSK_PC1ET2_1	821	823	PF00082	0.569
CLV_PCSK_PC7_1	817	823	PF00082	0.567
CLV_PCSK_SKI1_1	11	15	PF00082	0.586
CLV_PCSK_SKI1_1	233	237	PF00082	0.464
CLV_PCSK_SKI1_1	304	308	PF00082	0.613
CLV_PCSK_SKI1_1	476	480	PF00082	0.576
CLV_PCSK_SKI1_1	602	606	PF00082	0.455
CLV_PCSK_SKI1_1	638	642	PF00082	0.612
CLV_PCSK_SKI1_1	699	703	PF00082	0.479
CLV_PCSK_SKI1_1	72	76	PF00082	0.696
CLV_PCSK_SKI1_1	795	799	PF00082	0.661
CLV_PCSK_SKI1_1	859	863	PF00082	0.442
DEG_APCC_DBOX_1	232	240	PF00400	0.537
DEG_SCF_FBW7_1	584	590	PF00400	0.541
DEG_SCF_FBW7_2	267	274	PF00400	0.599
DOC_CKS1_1	268	273	PF01111	0.506
DOC_CKS1_1	584	589	PF01111	0.537
DOC_MAPK_DCC_7	671	681	PF00069	0.569
DOC_MAPK_gen_1	696	704	PF00069	0.494
DOC_MAPK_MEF2A_6	696	704	PF00069	0.494
DOC_MAPK_RevD_3	545	561	PF00069	0.523
DOC_PP2B_LxvP_1	116	119	PF13499	0.485
DOC_PP2B_LxvP_1	358	361	PF13499	0.619
DOC_PP2B_LxvP_1	547	550	PF13499	0.597
DOC_PP2B_LxvP_1	607	610	PF13499	0.415
DOC_PP2B_LxvP_1	679	682	PF13499	0.541
DOC_PP2B_LxvP_1	702	705	PF13499	0.482
DOC_PP4_FxxP_1	15	18	PF00568	0.581
DOC_USP7_MATH_1	119	123	PF00917	0.660
DOC_USP7_MATH_1	173	177	PF00917	0.661
DOC_USP7_MATH_1	197	201	PF00917	0.747
DOC_USP7_MATH_1	208	212	PF00917	0.572
DOC_USP7_MATH_1	220	224	PF00917	0.523
DOC_USP7_MATH_1	285	289	PF00917	0.605
DOC_USP7_MATH_1	292	296	PF00917	0.570
DOC_USP7_MATH_1	331	335	PF00917	0.578
DOC_USP7_MATH_1	364	368	PF00917	0.628
DOC_USP7_MATH_1	372	376	PF00917	0.556
DOC_USP7_MATH_1	433	437	PF00917	0.537
DOC_USP7_MATH_1	439	443	PF00917	0.531
DOC_USP7_MATH_1	571	575	PF00917	0.671
DOC_USP7_MATH_1	630	634	PF00917	0.607
DOC_USP7_MATH_1	718	722	PF00917	0.553
DOC_USP7_MATH_1	74	78	PF00917	0.777
DOC_USP7_MATH_1	829	833	PF00917	0.701
DOC_USP7_MATH_1	875	879	PF00917	0.500
DOC_WW_Pin1_4	155	160	PF00397	0.644
DOC_WW_Pin1_4	16	21	PF00397	0.565
DOC_WW_Pin1_4	165	170	PF00397	0.570
DOC_WW_Pin1_4	195	200	PF00397	0.562
DOC_WW_Pin1_4	204	209	PF00397	0.609
DOC_WW_Pin1_4	267	272	PF00397	0.513
DOC_WW_Pin1_4	296	301	PF00397	0.675
DOC_WW_Pin1_4	317	322	PF00397	0.528
DOC_WW_Pin1_4	583	588	PF00397	0.643
DOC_WW_Pin1_4	734	739	PF00397	0.588
DOC_WW_Pin1_4	749	754	PF00397	0.619
LIG_14-3-3_CanoR_1	144	150	PF00244	0.585
LIG_14-3-3_CanoR_1	497	506	PF00244	0.670
LIG_14-3-3_CanoR_1	53	57	PF00244	0.509
LIG_14-3-3_CanoR_1	551	556	PF00244	0.430
LIG_14-3-3_CanoR_1	570	579	PF00244	0.598
LIG_14-3-3_CanoR_1	611	620	PF00244	0.535
LIG_14-3-3_CanoR_1	822	831	PF00244	0.663
LIG_14-3-3_CanoR_1	859	865	PF00244	0.528
LIG_APCC_ABBA_1	232	237	PF00400	0.454
LIG_APCC_ABBA_1	880	885	PF00400	0.588
LIG_BIR_III_2	289	293	PF00653	0.609
LIG_BIR_III_4	133	137	PF00653	0.697
LIG_BIR_III_4	477	481	PF00653	0.525
LIG_BIR_III_4	744	748	PF00653	0.725
LIG_BRCT_BRCA1_1	18	22	PF00533	0.496
LIG_BRCT_BRCA1_1	720	724	PF00533	0.623
LIG_CaM_NSCaTE_8	336	343	PF13499	0.581
LIG_CSL_BTD_1	679	682	PF09270	0.541
LIG_deltaCOP1_diTrp_1	3	9	PF00928	0.569
LIG_deltaCOP1_diTrp_1	451	461	PF00928	0.529
LIG_FHA_1	108	114	PF00498	0.478
LIG_FHA_1	244	250	PF00498	0.573
LIG_FHA_1	268	274	PF00498	0.513
LIG_FHA_1	327	333	PF00498	0.592
LIG_FHA_1	43	49	PF00498	0.513
LIG_FHA_1	469	475	PF00498	0.606
LIG_FHA_1	53	59	PF00498	0.522
LIG_FHA_1	551	557	PF00498	0.458
LIG_FHA_1	613	619	PF00498	0.528
LIG_FHA_1	624	630	PF00498	0.455
LIG_FHA_1	762	768	PF00498	0.475
LIG_FHA_1	826	832	PF00498	0.543
LIG_FHA_1	855	861	PF00498	0.603
LIG_FHA_1	882	888	PF00498	0.581
LIG_FHA_1	896	902	PF00498	0.469
LIG_FHA_2	250	256	PF00498	0.595
LIG_FHA_2	26	32	PF00498	0.578
LIG_FHA_2	477	483	PF00498	0.614
LIG_FHA_2	488	494	PF00498	0.474
LIG_FHA_2	591	597	PF00498	0.627
LIG_FHA_2	71	77	PF00498	0.562
LIG_FHA_2	782	788	PF00498	0.562
LIG_FHA_2	890	896	PF00498	0.542
LIG_HCF-1_HBM_1	576	579	PF13415	0.526
LIG_LIR_Apic_2	265	271	PF02991	0.537
LIG_LIR_Apic_2	442	448	PF02991	0.587
LIG_LIR_Gen_1	19	26	PF02991	0.492
LIG_LIR_Gen_1	7	16	PF02991	0.576
LIG_LIR_Gen_1	721	732	PF02991	0.601
LIG_LIR_Gen_1	849	856	PF02991	0.546
LIG_LIR_Gen_1	98	109	PF02991	0.517
LIG_LIR_LC3C_4	615	620	PF02991	0.507
LIG_LIR_Nem_3	19	25	PF02991	0.491
LIG_LIR_Nem_3	276	281	PF02991	0.529
LIG_LIR_Nem_3	377	382	PF02991	0.604
LIG_LIR_Nem_3	446	450	PF02991	0.454
LIG_LIR_Nem_3	7	12	PF02991	0.568
LIG_LIR_Nem_3	708	714	PF02991	0.535
LIG_LIR_Nem_3	721	727	PF02991	0.523
LIG_LIR_Nem_3	849	854	PF02991	0.441
LIG_NRP_CendR_1	928	929	PF00754	0.699
LIG_Pex14_1	5	9	PF04695	0.567
LIG_Pex14_2	231	235	PF04695	0.409
LIG_REV1ctd_RIR_1	229	237	PF16727	0.426
LIG_SH2_CRK	268	272	PF00017	0.511
LIG_SH2_CRK	445	449	PF00017	0.564
LIG_SH2_CRK	711	715	PF00017	0.537
LIG_SH2_NCK_1	341	345	PF00017	0.518
LIG_SH2_SRC	675	678	PF00017	0.609
LIG_SH2_STAT3	603	606	PF00017	0.414
LIG_SH2_STAT5	112	115	PF00017	0.468
LIG_SH2_STAT5	382	385	PF00017	0.589
LIG_SH2_STAT5	555	558	PF00017	0.553
LIG_SH2_STAT5	603	606	PF00017	0.414
LIG_SH2_STAT5	675	678	PF00017	0.534
LIG_SH2_STAT5	780	783	PF00017	0.475
LIG_SH3_1	671	677	PF00018	0.524
LIG_SH3_3	190	196	PF00018	0.481
LIG_SH3_3	295	301	PF00018	0.546
LIG_SH3_3	315	321	PF00018	0.556
LIG_SH3_3	357	363	PF00018	0.643
LIG_SH3_3	521	527	PF00018	0.635
LIG_SH3_3	540	546	PF00018	0.481
LIG_SH3_3	581	587	PF00018	0.539
LIG_SH3_3	671	677	PF00018	0.623
LIG_SH3_3	750	756	PF00018	0.611
LIG_SH3_3	797	803	PF00018	0.574
LIG_SUMO_SIM_par_1	189	194	PF11976	0.593
LIG_SUMO_SIM_par_1	54	60	PF11976	0.606
LIG_TRAF2_1	28	31	PF00917	0.577
LIG_TRAF2_1	843	846	PF00917	0.495
LIG_TRAF2_1	907	910	PF00917	0.470
LIG_TRAF2_1	911	914	PF00917	0.486
LIG_TRAF2_2	159	164	PF00917	0.633
MOD_CDK_SPxxK_3	734	741	PF00069	0.601
MOD_CK1_1	132	138	PF00069	0.641
MOD_CK1_1	165	171	PF00069	0.621
MOD_CK1_1	198	204	PF00069	0.663
MOD_CK1_1	247	253	PF00069	0.613
MOD_CK1_1	299	305	PF00069	0.701
MOD_CK1_1	310	316	PF00069	0.602
MOD_CK1_1	339	345	PF00069	0.570
MOD_CK1_1	377	383	PF00069	0.656
MOD_CK1_1	443	449	PF00069	0.549
MOD_CK1_1	500	506	PF00069	0.695
MOD_CK1_1	528	534	PF00069	0.661
MOD_CK1_1	648	654	PF00069	0.525
MOD_CK1_1	734	740	PF00069	0.606
MOD_CK1_1	752	758	PF00069	0.776
MOD_CK1_1	95	101	PF00069	0.587
MOD_CK2_1	100	106	PF00069	0.613
MOD_CK2_1	25	31	PF00069	0.580
MOD_CK2_1	4	10	PF00069	0.567
MOD_CK2_1	487	493	PF00069	0.682
MOD_CK2_1	594	600	PF00069	0.574
MOD_CK2_1	781	787	PF00069	0.556
MOD_CK2_1	801	807	PF00069	0.462
MOD_CK2_1	902	908	PF00069	0.595
MOD_Cter_Amidation	635	638	PF01082	0.555
MOD_GlcNHglycan	133	137	PF01048	0.655
MOD_GlcNHglycan	140	143	PF01048	0.601
MOD_GlcNHglycan	164	167	PF01048	0.688
MOD_GlcNHglycan	175	178	PF01048	0.559
MOD_GlcNHglycan	208	211	PF01048	0.660
MOD_GlcNHglycan	246	249	PF01048	0.616
MOD_GlcNHglycan	294	297	PF01048	0.628
MOD_GlcNHglycan	301	304	PF01048	0.635
MOD_GlcNHglycan	333	336	PF01048	0.646
MOD_GlcNHglycan	341	344	PF01048	0.541
MOD_GlcNHglycan	355	358	PF01048	0.607
MOD_GlcNHglycan	366	369	PF01048	0.653
MOD_GlcNHglycan	396	399	PF01048	0.486
MOD_GlcNHglycan	435	438	PF01048	0.558
MOD_GlcNHglycan	482	485	PF01048	0.627
MOD_GlcNHglycan	530	533	PF01048	0.638
MOD_GlcNHglycan	6	9	PF01048	0.568
MOD_GlcNHglycan	646	650	PF01048	0.616
MOD_GlcNHglycan	666	669	PF01048	0.454
MOD_GlcNHglycan	690	693	PF01048	0.531
MOD_GlcNHglycan	696	699	PF01048	0.511
MOD_GlcNHglycan	733	736	PF01048	0.575
MOD_GlcNHglycan	76	79	PF01048	0.699
MOD_GlcNHglycan	775	778	PF01048	0.427
MOD_GlcNHglycan	831	834	PF01048	0.609
MOD_GlcNHglycan	848	851	PF01048	0.514
MOD_GSK3_1	100	107	PF00069	0.524
MOD_GSK3_1	132	139	PF00069	0.556
MOD_GSK3_1	151	158	PF00069	0.687
MOD_GSK3_1	191	198	PF00069	0.607
MOD_GSK3_1	204	211	PF00069	0.660
MOD_GSK3_1	21	28	PF00069	0.554
MOD_GSK3_1	214	221	PF00069	0.599
MOD_GSK3_1	243	250	PF00069	0.613
MOD_GSK3_1	263	270	PF00069	0.588
MOD_GSK3_1	292	299	PF00069	0.665
MOD_GSK3_1	326	333	PF00069	0.551
MOD_GSK3_1	439	446	PF00069	0.516
MOD_GSK3_1	476	483	PF00069	0.730
MOD_GSK3_1	500	507	PF00069	0.582
MOD_GSK3_1	528	535	PF00069	0.657
MOD_GSK3_1	57	64	PF00069	0.628
MOD_GSK3_1	583	590	PF00069	0.707
MOD_GSK3_1	638	645	PF00069	0.561
MOD_GSK3_1	688	695	PF00069	0.693
MOD_GSK3_1	70	77	PF00069	0.548
MOD_GSK3_1	718	725	PF00069	0.733
MOD_GSK3_1	748	755	PF00069	0.794
MOD_GSK3_1	757	764	PF00069	0.641
MOD_GSK3_1	789	796	PF00069	0.524
MOD_GSK3_1	821	828	PF00069	0.599
MOD_GSK3_1	91	98	PF00069	0.653
MOD_LATS_1	2	8	PF00433	0.493
MOD_N-GLC_1	571	576	PF02516	0.605
MOD_N-GLC_2	763	765	PF02516	0.538
MOD_NEK2_1	104	109	PF00069	0.482
MOD_NEK2_1	145	150	PF00069	0.581
MOD_NEK2_1	414	419	PF00069	0.478
MOD_NEK2_1	499	504	PF00069	0.603
MOD_NEK2_1	63	68	PF00069	0.627
MOD_NEK2_1	761	766	PF00069	0.538
MOD_NEK2_1	781	786	PF00069	0.404
MOD_NEK2_1	789	794	PF00069	0.470
MOD_NEK2_1	860	865	PF00069	0.591
MOD_NEK2_1	92	97	PF00069	0.647
MOD_NEK2_2	336	341	PF00069	0.611
MOD_NEK2_2	382	387	PF00069	0.495
MOD_NEK2_2	532	537	PF00069	0.576
MOD_OFUCOSY	758	765	PF10250	0.564
MOD_PIKK_1	310	316	PF00454	0.609
MOD_PIKK_1	372	378	PF00454	0.516
MOD_PIKK_1	460	466	PF00454	0.522
MOD_PIKK_1	594	600	PF00454	0.583
MOD_PIKK_1	801	807	PF00454	0.598
MOD_PKA_1	497	503	PF00069	0.612
MOD_PKA_1	821	827	PF00069	0.627
MOD_PKA_2	145	151	PF00069	0.674
MOD_PKA_2	162	168	PF00069	0.555
MOD_PKA_2	497	503	PF00069	0.612
MOD_PKA_2	52	58	PF00069	0.576
MOD_PKA_2	550	556	PF00069	0.436
MOD_PKA_2	747	753	PF00069	0.581
MOD_PKA_2	821	827	PF00069	0.627
MOD_PKA_2	890	896	PF00069	0.524
MOD_Plk_1	645	651	PF00069	0.531
MOD_Plk_1	781	787	PF00069	0.506
MOD_Plk_4	107	113	PF00069	0.483
MOD_Plk_4	145	151	PF00069	0.591
MOD_Plk_4	21	27	PF00069	0.583
MOD_Plk_4	263	269	PF00069	0.649
MOD_Plk_4	307	313	PF00069	0.607
MOD_Plk_4	336	342	PF00069	0.665
MOD_Plk_4	382	388	PF00069	0.493
MOD_Plk_4	422	428	PF00069	0.507
MOD_Plk_4	440	446	PF00069	0.548
MOD_Plk_4	551	557	PF00069	0.426
MOD_Plk_4	624	630	PF00069	0.579
MOD_Plk_4	675	681	PF00069	0.527
MOD_Plk_4	726	732	PF00069	0.672
MOD_Plk_4	793	799	PF00069	0.749
MOD_Plk_4	875	881	PF00069	0.468
MOD_ProDKin_1	155	161	PF00069	0.647
MOD_ProDKin_1	16	22	PF00069	0.566
MOD_ProDKin_1	165	171	PF00069	0.570
MOD_ProDKin_1	195	201	PF00069	0.566
MOD_ProDKin_1	204	210	PF00069	0.607
MOD_ProDKin_1	267	273	PF00069	0.508
MOD_ProDKin_1	296	302	PF00069	0.675
MOD_ProDKin_1	317	323	PF00069	0.531
MOD_ProDKin_1	583	589	PF00069	0.641
MOD_ProDKin_1	734	740	PF00069	0.594
MOD_ProDKin_1	749	755	PF00069	0.615
TRG_DiLeu_BaEn_4	30	36	PF01217	0.571
TRG_DiLeu_BaEn_4	600	606	PF01217	0.521
TRG_DiLeu_BaLyEn_6	696	701	PF01217	0.587
TRG_ENDOCYTIC_2	711	714	PF00928	0.533
TRG_ER_diArg_1	37	39	PF00400	0.571
TRG_ER_diArg_1	496	498	PF00400	0.518
TRG_ER_diArg_1	557	560	PF00400	0.481
TRG_ER_diArg_1	815	817	PF00400	0.603
TRG_ER_diArg_1	887	889	PF00400	0.586
TRG_NLS_MonoExtC_3	816	821	PF00514	0.511
TRG_NLS_MonoExtN_4	816	821	PF00514	0.529
TRG_Pf-PMV_PEXEL_1	460	464	PF00026	0.512
TRG_Pf-PMV_PEXEL_1	472	477	PF00026	0.535

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEF8	Leptomonas seymouri	40%	100%
A0A3S5H5X7	Leishmania donovani	89%	100%
A4H4Y5	Leishmania braziliensis	73%	100%
A4HT29	Leishmania infantum	89%	100%
E9AL50	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%