Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIN8_LEIMA

TriTrypDb:

LmjF.07.0540 , LMJLV39_070011600 , LMJSD75_070011800

Length:

743

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIN8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIN8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	274	278	PF00656	0.743
CLV_C14_Caspase3-7	329	333	PF00656	0.736
CLV_C14_Caspase3-7	683	687	PF00656	0.642
CLV_NRD_NRD_1	108	110	PF00675	0.758
CLV_NRD_NRD_1	178	180	PF00675	0.549
CLV_NRD_NRD_1	21	23	PF00675	0.757
CLV_NRD_NRD_1	226	228	PF00675	0.622
CLV_NRD_NRD_1	528	530	PF00675	0.711
CLV_NRD_NRD_1	576	578	PF00675	0.642
CLV_NRD_NRD_1	66	68	PF00675	0.697
CLV_NRD_NRD_1	670	672	PF00675	0.537
CLV_NRD_NRD_1	7	9	PF00675	0.623
CLV_PCSK_FUR_1	618	622	PF00082	0.707
CLV_PCSK_FUR_1	64	68	PF00082	0.706
CLV_PCSK_KEX2_1	108	110	PF00082	0.758
CLV_PCSK_KEX2_1	178	180	PF00082	0.549
CLV_PCSK_KEX2_1	21	23	PF00082	0.757
CLV_PCSK_KEX2_1	226	228	PF00082	0.622
CLV_PCSK_KEX2_1	528	530	PF00082	0.746
CLV_PCSK_KEX2_1	551	553	PF00082	0.593
CLV_PCSK_KEX2_1	575	577	PF00082	0.686
CLV_PCSK_KEX2_1	620	622	PF00082	0.739
CLV_PCSK_KEX2_1	66	68	PF00082	0.697
CLV_PCSK_KEX2_1	670	672	PF00082	0.573
CLV_PCSK_KEX2_1	7	9	PF00082	0.623
CLV_PCSK_PC1ET2_1	551	553	PF00082	0.593
CLV_PCSK_PC1ET2_1	620	622	PF00082	0.704
CLV_PCSK_PC7_1	524	530	PF00082	0.720
CLV_PCSK_SKI1_1	182	186	PF00082	0.428
CLV_PCSK_SKI1_1	552	556	PF00082	0.552
CLV_PCSK_SKI1_1	620	624	PF00082	0.591
CLV_PCSK_SKI1_1	670	674	PF00082	0.583
CLV_PCSK_SKI1_1	739	743	PF00082	0.588
DEG_COP1_1	86	94	PF00400	0.592
DEG_Kelch_Keap1_1	509	514	PF01344	0.762
DEG_SPOP_SBC_1	141	145	PF00917	0.749
DEG_SPOP_SBC_1	351	355	PF00917	0.737
DOC_CKS1_1	1	6	PF01111	0.633
DOC_CKS1_1	604	609	PF01111	0.573
DOC_MAPK_DCC_7	154	164	PF00069	0.704
DOC_MAPK_gen_1	551	560	PF00069	0.563
DOC_MAPK_gen_1	562	569	PF00069	0.415
DOC_MAPK_gen_1	575	582	PF00069	0.404
DOC_MAPK_MEF2A_6	341	348	PF00069	0.587
DOC_MAPK_MEF2A_6	575	582	PF00069	0.412
DOC_PP2B_LxvP_1	95	98	PF13499	0.630
DOC_PP4_FxxP_1	448	451	PF00568	0.726
DOC_USP7_MATH_1	148	152	PF00917	0.684
DOC_USP7_MATH_1	24	28	PF00917	0.717
DOC_USP7_MATH_1	350	354	PF00917	0.778
DOC_USP7_MATH_1	356	360	PF00917	0.693
DOC_USP7_MATH_1	393	397	PF00917	0.746
DOC_USP7_MATH_1	413	417	PF00917	0.652
DOC_USP7_MATH_1	419	423	PF00917	0.641
DOC_USP7_MATH_1	459	463	PF00917	0.785
DOC_USP7_MATH_1	46	50	PF00917	0.779
DOC_USP7_MATH_1	85	89	PF00917	0.747
DOC_USP7_MATH_1	90	94	PF00917	0.625
DOC_USP7_MATH_2	161	167	PF00917	0.689
DOC_USP7_UBL2_3	551	555	PF12436	0.583
DOC_WW_Pin1_4	134	139	PF00397	0.729
DOC_WW_Pin1_4	22	27	PF00397	0.702
DOC_WW_Pin1_4	264	269	PF00397	0.766
DOC_WW_Pin1_4	346	351	PF00397	0.739
DOC_WW_Pin1_4	367	372	PF00397	0.744
DOC_WW_Pin1_4	399	404	PF00397	0.737
DOC_WW_Pin1_4	461	466	PF00397	0.712
DOC_WW_Pin1_4	54	59	PF00397	0.800
DOC_WW_Pin1_4	603	608	PF00397	0.553
DOC_WW_Pin1_4	97	102	PF00397	0.764
LIG_14-3-3_CanoR_1	272	282	PF00244	0.772
LIG_14-3-3_CanoR_1	445	451	PF00244	0.619
LIG_14-3-3_CanoR_1	737	742	PF00244	0.549
LIG_14-3-3_CanoR_1	78	82	PF00244	0.613
LIG_14-3-3_CanoR_1	8	18	PF00244	0.774
LIG_14-3-3_CterR_2	739	743	PF00244	0.588
LIG_BIR_III_2	380	384	PF00653	0.594
LIG_Clathr_ClatBox_1	647	651	PF01394	0.489
LIG_FHA_1	240	246	PF00498	0.643
LIG_FHA_1	307	313	PF00498	0.730
LIG_FHA_1	314	320	PF00498	0.635
LIG_FHA_1	389	395	PF00498	0.670
LIG_FHA_1	564	570	PF00498	0.627
LIG_FHA_2	272	278	PF00498	0.719
LIG_FHA_2	327	333	PF00498	0.731
LIG_FHA_2	604	610	PF00498	0.578
LIG_LIR_Apic_2	122	128	PF02991	0.749
LIG_LIR_Apic_2	292	298	PF02991	0.732
LIG_LIR_Apic_2	603	607	PF02991	0.538
LIG_LIR_Gen_1	110	119	PF02991	0.748
LIG_LIR_Nem_3	110	116	PF02991	0.752
LIG_LIR_Nem_3	217	222	PF02991	0.554
LIG_LIR_Nem_3	404	410	PF02991	0.742
LIG_MYND_1	132	136	PF01753	0.724
LIG_PDZ_Class_2	738	743	PF00595	0.570
LIG_SH2_CRK	219	223	PF00017	0.549
LIG_SH2_CRK	295	299	PF00017	0.746
LIG_SH2_GRB2like	81	84	PF00017	0.724
LIG_SH2_PTP2	215	218	PF00017	0.539
LIG_SH2_SRC	113	116	PF00017	0.751
LIG_SH2_SRC	81	84	PF00017	0.724
LIG_SH2_STAP1	188	192	PF00017	0.624
LIG_SH2_STAP1	641	645	PF00017	0.527
LIG_SH2_STAT3	266	269	PF00017	0.624
LIG_SH2_STAT3	483	486	PF00017	0.616
LIG_SH2_STAT5	183	186	PF00017	0.561
LIG_SH2_STAT5	215	218	PF00017	0.539
LIG_SH2_STAT5	266	269	PF00017	0.729
LIG_SH2_STAT5	654	657	PF00017	0.495
LIG_SH2_STAT5	81	84	PF00017	0.724
LIG_SH3_1	368	374	PF00018	0.739
LIG_SH3_2	255	260	PF14604	0.723
LIG_SH3_2	403	408	PF14604	0.692
LIG_SH3_2	98	103	PF14604	0.608
LIG_SH3_3	12	18	PF00018	0.724
LIG_SH3_3	130	136	PF00018	0.732
LIG_SH3_3	235	241	PF00018	0.655
LIG_SH3_3	248	254	PF00018	0.653
LIG_SH3_3	368	374	PF00018	0.739
LIG_SH3_3	400	406	PF00018	0.727
LIG_SH3_3	594	600	PF00018	0.547
LIG_SH3_3	95	101	PF00018	0.681
LIG_SUMO_SIM_par_1	711	717	PF11976	0.470
LIG_TRAF2_1	112	115	PF00917	0.754
LIG_TRAF2_1	361	364	PF00917	0.746
MOD_CDC14_SPxK_1	100	103	PF00782	0.608
MOD_CDK_SPxK_1	97	103	PF00069	0.620
MOD_CDK_SPxxK_3	401	408	PF00069	0.695
MOD_CK1_1	121	127	PF00069	0.748
MOD_CK1_1	25	31	PF00069	0.755
MOD_CK1_1	273	279	PF00069	0.687
MOD_CK1_1	285	291	PF00069	0.716
MOD_CK1_1	354	360	PF00069	0.665
MOD_CK1_1	376	382	PF00069	0.593
MOD_CK1_1	422	428	PF00069	0.626
MOD_CK1_1	489	495	PF00069	0.750
MOD_CK1_1	507	513	PF00069	0.557
MOD_CK1_1	543	549	PF00069	0.694
MOD_CK1_1	563	569	PF00069	0.553
MOD_CK1_1	678	684	PF00069	0.678
MOD_CK1_1	93	99	PF00069	0.766
MOD_CK2_1	286	292	PF00069	0.707
MOD_CK2_1	33	39	PF00069	0.768
MOD_CK2_1	508	514	PF00069	0.762
MOD_CK2_1	56	62	PF00069	0.762
MOD_CK2_1	603	609	PF00069	0.461
MOD_Cter_Amidation	526	529	PF01082	0.719
MOD_Cter_Amidation	64	67	PF01082	0.713
MOD_GlcNHglycan	12	15	PF01048	0.829
MOD_GlcNHglycan	150	153	PF01048	0.726
MOD_GlcNHglycan	202	205	PF01048	0.591
MOD_GlcNHglycan	285	288	PF01048	0.752
MOD_GlcNHglycan	304	307	PF01048	0.740
MOD_GlcNHglycan	334	337	PF01048	0.753
MOD_GlcNHglycan	35	39	PF01048	0.737
MOD_GlcNHglycan	356	359	PF01048	0.721
MOD_GlcNHglycan	415	418	PF01048	0.620
MOD_GlcNHglycan	448	451	PF01048	0.726
MOD_GlcNHglycan	457	460	PF01048	0.655
MOD_GlcNHglycan	511	514	PF01048	0.846
MOD_GlcNHglycan	532	535	PF01048	0.652
MOD_GlcNHglycan	546	549	PF01048	0.583
MOD_GlcNHglycan	83	86	PF01048	0.758
MOD_GlcNHglycan	95	98	PF01048	0.601
MOD_GSK3_1	142	149	PF00069	0.773
MOD_GSK3_1	282	289	PF00069	0.800
MOD_GSK3_1	302	309	PF00069	0.730
MOD_GSK3_1	34	41	PF00069	0.736
MOD_GSK3_1	340	347	PF00069	0.696
MOD_GSK3_1	350	357	PF00069	0.594
MOD_GSK3_1	388	395	PF00069	0.631
MOD_GSK3_1	455	462	PF00069	0.712
MOD_GSK3_1	47	54	PF00069	0.635
MOD_GSK3_1	504	511	PF00069	0.834
MOD_GSK3_1	540	547	PF00069	0.736
MOD_GSK3_1	588	595	PF00069	0.544
MOD_GSK3_1	73	80	PF00069	0.768
MOD_GSK3_1	81	88	PF00069	0.701
MOD_GSK3_1	93	100	PF00069	0.587
MOD_N-GLC_1	283	288	PF02516	0.710
MOD_N-GLC_1	737	742	PF02516	0.549
MOD_N-GLC_2	677	679	PF02516	0.567
MOD_NEK2_1	218	223	PF00069	0.559
MOD_NEK2_1	231	236	PF00069	0.742
MOD_NEK2_1	282	287	PF00069	0.746
MOD_NEK2_1	302	307	PF00069	0.736
MOD_NEK2_1	440	445	PF00069	0.746
MOD_NEK2_1	540	545	PF00069	0.732
MOD_NEK2_1	560	565	PF00069	0.563
MOD_OFUCOSY	674	679	PF10250	0.547
MOD_PIKK_1	119	125	PF00454	0.740
MOD_PIKK_1	440	446	PF00454	0.741
MOD_PIKK_1	540	546	PF00454	0.730
MOD_PKA_2	271	277	PF00069	0.773
MOD_PKA_2	340	346	PF00069	0.728
MOD_PKA_2	563	569	PF00069	0.553
MOD_PKA_2	592	598	PF00069	0.418
MOD_PKA_2	77	83	PF00069	0.702
MOD_PKA_2	9	15	PF00069	0.701
MOD_PKB_1	260	268	PF00069	0.767
MOD_PKB_1	8	16	PF00069	0.620
MOD_Plk_1	231	237	PF00069	0.657
MOD_Plk_1	486	492	PF00069	0.749
MOD_Plk_1	73	79	PF00069	0.580
MOD_Plk_1	737	743	PF00069	0.566
MOD_Plk_4	232	238	PF00069	0.663
MOD_Plk_4	25	31	PF00069	0.733
MOD_Plk_4	393	399	PF00069	0.692
MOD_Plk_4	714	720	PF00069	0.557
MOD_Plk_4	77	83	PF00069	0.721
MOD_Plk_4	90	96	PF00069	0.546
MOD_ProDKin_1	134	140	PF00069	0.734
MOD_ProDKin_1	22	28	PF00069	0.701
MOD_ProDKin_1	264	270	PF00069	0.764
MOD_ProDKin_1	346	352	PF00069	0.741
MOD_ProDKin_1	367	373	PF00069	0.744
MOD_ProDKin_1	399	405	PF00069	0.731
MOD_ProDKin_1	461	467	PF00069	0.713
MOD_ProDKin_1	54	60	PF00069	0.794
MOD_ProDKin_1	603	609	PF00069	0.563
MOD_ProDKin_1	97	103	PF00069	0.760
MOD_SUMO_for_1	672	675	PF00179	0.457
TRG_DiLeu_BaEn_2	159	165	PF01217	0.662
TRG_DiLeu_BaEn_2	231	237	PF01217	0.657
TRG_DiLeu_LyEn_5	556	561	PF01217	0.396
TRG_ENDOCYTIC_2	113	116	PF00928	0.751
TRG_ENDOCYTIC_2	215	218	PF00928	0.539
TRG_ENDOCYTIC_2	219	222	PF00928	0.507
TRG_ENDOCYTIC_2	407	410	PF00928	0.742
TRG_ER_diArg_1	177	179	PF00400	0.547
TRG_ER_diArg_1	366	369	PF00400	0.757
TRG_ER_diArg_1	497	500	PF00400	0.621
TRG_ER_diArg_1	561	564	PF00400	0.580
TRG_ER_diArg_1	575	577	PF00400	0.533
TRG_ER_diArg_1	6	8	PF00400	0.614
TRG_ER_diArg_1	63	66	PF00400	0.713
TRG_ER_diArg_1	669	671	PF00400	0.518
TRG_NLS_MonoExtN_4	617	624	PF00514	0.699
TRG_Pf-PMV_PEXEL_1	552	556	PF00026	0.592

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H5Y4	Leishmania donovani	91%	67%
A4HT74	Leishmania infantum	91%	67%
E9AL66	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%