Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIN0_LEIMA

TriTrypDb:

LmjF.07.0615 , LMJLV39_070012400 , LMJSD75_070012600

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIN0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIN0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	12	16	PF00656	0.523
CLV_PCSK_KEX2_1	222	224	PF00082	0.757
CLV_PCSK_PC1ET2_1	222	224	PF00082	0.740
DEG_COP1_1	120	130	PF00400	0.447
DEG_SCF_FBW7_1	146	153	PF00400	0.615
DEG_SPOP_SBC_1	131	135	PF00917	0.621
DOC_CKS1_1	147	152	PF01111	0.695
DOC_CYCLIN_yCln2_LP_2	34	40	PF00134	0.496
DOC_MAPK_JIP1_4	2	8	PF00069	0.478
DOC_MAPK_MEF2A_6	2	10	PF00069	0.357
DOC_PP1_RVXF_1	187	193	PF00149	0.379
DOC_PP2B_LxvP_1	34	37	PF13499	0.534
DOC_PP2B_LxvP_1	8	11	PF13499	0.319
DOC_USP7_MATH_1	125	129	PF00917	0.691
DOC_USP7_MATH_1	141	145	PF00917	0.484
DOC_USP7_MATH_1	150	154	PF00917	0.574
DOC_USP7_MATH_1	21	25	PF00917	0.638
DOC_USP7_MATH_1	61	65	PF00917	0.673
DOC_WW_Pin1_4	146	151	PF00397	0.634
DOC_WW_Pin1_4	163	168	PF00397	0.428
DOC_WW_Pin1_4	251	256	PF00397	0.398
LIG_14-3-3_CanoR_1	187	193	PF00244	0.471
LIG_Actin_WH2_2	1	16	PF00022	0.331
LIG_FHA_1	242	248	PF00498	0.470
LIG_FHA_1	31	37	PF00498	0.459
LIG_FHA_1	42	48	PF00498	0.379
LIG_FHA_1	74	80	PF00498	0.728
LIG_FHA_1	88	94	PF00498	0.392
LIG_FHA_2	147	153	PF00498	0.608
LIG_FHA_2	181	187	PF00498	0.511
LIG_LIR_Gen_1	174	181	PF02991	0.391
LIG_LIR_Gen_1	191	196	PF02991	0.372
LIG_LIR_Nem_3	174	179	PF02991	0.394
LIG_LIR_Nem_3	191	195	PF02991	0.362
LIG_Pex14_2	172	176	PF04695	0.528
LIG_RPA_C_Fungi	204	216	PF08784	0.578
LIG_SH2_STAT5	110	113	PF00017	0.498
LIG_SH3_3	124	130	PF00018	0.606
LIG_SH3_3	144	150	PF00018	0.719
LIG_SH3_3	33	39	PF00018	0.434
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.416
LIG_SUMO_SIM_par_1	242	248	PF11976	0.462
MOD_CK1_1	135	141	PF00069	0.659
MOD_CK1_1	24	30	PF00069	0.552
MOD_CK1_1	64	70	PF00069	0.692
MOD_CK1_1	78	84	PF00069	0.705
MOD_CK2_1	180	186	PF00069	0.517
MOD_Cter_Amidation	220	223	PF01082	0.740
MOD_DYRK1A_RPxSP_1	165	169	PF00069	0.471
MOD_GlcNHglycan	104	107	PF01048	0.460
MOD_GlcNHglycan	127	130	PF01048	0.691
MOD_GlcNHglycan	134	137	PF01048	0.670
MOD_GlcNHglycan	173	176	PF01048	0.454
MOD_GlcNHglycan	213	216	PF01048	0.551
MOD_GlcNHglycan	23	26	PF01048	0.644
MOD_GlcNHglycan	235	239	PF01048	0.605
MOD_GlcNHglycan	27	30	PF01048	0.592
MOD_GlcNHglycan	47	50	PF01048	0.452
MOD_GlcNHglycan	59	62	PF01048	0.597
MOD_GSK3_1	131	138	PF00069	0.622
MOD_GSK3_1	141	148	PF00069	0.554
MOD_GSK3_1	207	214	PF00069	0.537
MOD_GSK3_1	21	28	PF00069	0.633
MOD_GSK3_1	241	248	PF00069	0.408
MOD_GSK3_1	41	48	PF00069	0.385
MOD_GSK3_1	57	64	PF00069	0.733
MOD_GSK3_1	75	82	PF00069	0.652
MOD_N-GLC_1	207	212	PF02516	0.677
MOD_N-GLC_1	64	69	PF02516	0.491
MOD_NEK2_1	119	124	PF00069	0.586
MOD_NEK2_1	190	195	PF00069	0.477
MOD_NEK2_1	234	239	PF00069	0.666
MOD_NEK2_1	45	50	PF00069	0.358
MOD_PIKK_1	180	186	PF00454	0.508
MOD_PKA_2	188	194	PF00069	0.426
MOD_PKA_2	21	27	PF00069	0.617
MOD_Plk_1	207	213	PF00069	0.606
MOD_Plk_1	241	247	PF00069	0.408
MOD_Plk_4	245	251	PF00069	0.391
MOD_Plk_4	79	85	PF00069	0.539
MOD_ProDKin_1	146	152	PF00069	0.631
MOD_ProDKin_1	163	169	PF00069	0.422
MOD_ProDKin_1	251	257	PF00069	0.414
TRG_ER_diArg_1	187	190	PF00400	0.472
TRG_Pf-PMV_PEXEL_1	222	226	PF00026	0.649

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P403	Leptomonas seymouri	42%	99%
A0A1X0NPF9	Trypanosomatidae	25%	100%
A0A3R7K387	Trypanosoma rangeli	29%	100%
A0A3S5H5Y8	Leishmania donovani	83%	100%
A4H512	Leishmania braziliensis	66%	100%
A4HT86	Leishmania infantum	84%	100%
C9ZUN8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
E9AL74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%