LeishMANIAdb
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Calcium-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Calcium-transporting ATPase
Gene product:
vacuolar-type Ca2+-ATPase, putative
Species:
Leishmania major
UniProt:
Q4QIM6_LEIMA
TriTrypDb:
LmjF.07.0650 , LMJLV39_000019900 * , LMJSD75_070012800 *
Length:
1119

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 20
NetGPI no yes: 0, no: 20
Cellular components
Term Name Level Count
GO:0005886 plasma membrane 3 4
GO:0016020 membrane 2 21
GO:0043226 organelle 2 4
GO:0043227 membrane-bounded organelle 3 4
GO:0043229 intracellular organelle 3 4
GO:0043231 intracellular membrane-bounded organelle 4 4
GO:0110165 cellular anatomical entity 1 21

Expansion

Sequence features

Q4QIM6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIM6

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 21
GO:0003824 catalytic activity 1 21
GO:0005215 transporter activity 1 16
GO:0005388 P-type calcium transporter activity 4 16
GO:0005488 binding 1 21
GO:0005524 ATP binding 5 21
GO:0008324 monoatomic cation transmembrane transporter activity 4 16
GO:0015075 monoatomic ion transmembrane transporter activity 3 16
GO:0015085 calcium ion transmembrane transporter activity 6 16
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 16
GO:0015399 primary active transmembrane transporter activity 4 16
GO:0015662 P-type ion transporter activity 4 16
GO:0016462 pyrophosphatase activity 5 21
GO:0016787 hydrolase activity 2 21
GO:0016817 hydrolase activity, acting on acid anhydrides 3 21
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 21
GO:0016887 ATP hydrolysis activity 7 21
GO:0017076 purine nucleotide binding 4 21
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 21
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 16
GO:0022804 active transmembrane transporter activity 3 16
GO:0022853 active monoatomic ion transmembrane transporter activity 4 16
GO:0022857 transmembrane transporter activity 2 16
GO:0022890 inorganic cation transmembrane transporter activity 4 16
GO:0030554 adenyl nucleotide binding 5 21
GO:0032553 ribonucleotide binding 3 21
GO:0032555 purine ribonucleotide binding 4 21
GO:0032559 adenyl ribonucleotide binding 5 21
GO:0035639 purine ribonucleoside triphosphate binding 4 21
GO:0036094 small molecule binding 2 21
GO:0042626 ATPase-coupled transmembrane transporter activity 2 16
GO:0043167 ion binding 2 21
GO:0043168 anion binding 3 21
GO:0046873 metal ion transmembrane transporter activity 5 16
GO:0097159 organic cyclic compound binding 2 21
GO:0097367 carbohydrate derivative binding 2 21
GO:0140358 P-type transmembrane transporter activity 3 16
GO:0140657 ATP-dependent activity 1 16
GO:1901265 nucleoside phosphate binding 3 21
GO:1901363 heterocyclic compound binding 2 21

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 106 110 PF00656 0.511
CLV_C14_Caspase3-7 529 533 PF00656 0.456
CLV_C14_Caspase3-7 663 667 PF00656 0.488
CLV_NRD_NRD_1 1077 1079 PF00675 0.374
CLV_NRD_NRD_1 1105 1107 PF00675 0.432
CLV_NRD_NRD_1 116 118 PF00675 0.263
CLV_NRD_NRD_1 220 222 PF00675 0.358
CLV_NRD_NRD_1 38 40 PF00675 0.504
CLV_NRD_NRD_1 413 415 PF00675 0.383
CLV_NRD_NRD_1 49 51 PF00675 0.410
CLV_NRD_NRD_1 561 563 PF00675 0.279
CLV_NRD_NRD_1 821 823 PF00675 0.290
CLV_NRD_NRD_1 889 891 PF00675 0.282
CLV_NRD_NRD_1 954 956 PF00675 0.267
CLV_PCSK_FUR_1 1075 1079 PF00082 0.271
CLV_PCSK_FUR_1 1103 1107 PF00082 0.463
CLV_PCSK_FUR_1 218 222 PF00082 0.275
CLV_PCSK_KEX2_1 1077 1079 PF00082 0.433
CLV_PCSK_KEX2_1 1103 1105 PF00082 0.419
CLV_PCSK_KEX2_1 116 118 PF00082 0.268
CLV_PCSK_KEX2_1 203 205 PF00082 0.495
CLV_PCSK_KEX2_1 220 222 PF00082 0.337
CLV_PCSK_KEX2_1 413 415 PF00082 0.383
CLV_PCSK_KEX2_1 455 457 PF00082 0.364
CLV_PCSK_KEX2_1 48 50 PF00082 0.533
CLV_PCSK_KEX2_1 53 55 PF00082 0.494
CLV_PCSK_KEX2_1 563 565 PF00082 0.295
CLV_PCSK_KEX2_1 884 886 PF00082 0.342
CLV_PCSK_PC1ET2_1 203 205 PF00082 0.383
CLV_PCSK_PC1ET2_1 455 457 PF00082 0.299
CLV_PCSK_PC1ET2_1 53 55 PF00082 0.528
CLV_PCSK_PC1ET2_1 563 565 PF00082 0.296
CLV_PCSK_PC1ET2_1 884 886 PF00082 0.256
CLV_PCSK_PC7_1 49 55 PF00082 0.346
CLV_PCSK_SKI1_1 1047 1051 PF00082 0.417
CLV_PCSK_SKI1_1 116 120 PF00082 0.282
CLV_PCSK_SKI1_1 122 126 PF00082 0.265
CLV_PCSK_SKI1_1 224 228 PF00082 0.342
CLV_PCSK_SKI1_1 369 373 PF00082 0.258
CLV_PCSK_SKI1_1 49 53 PF00082 0.490
CLV_PCSK_SKI1_1 551 555 PF00082 0.338
CLV_PCSK_SKI1_1 726 730 PF00082 0.282
CLV_PCSK_SKI1_1 748 752 PF00082 0.261
CLV_PCSK_SKI1_1 822 826 PF00082 0.275
CLV_PCSK_SKI1_1 970 974 PF00082 0.247
DEG_Nend_UBRbox_1 1 4 PF02207 0.704
DEG_SCF_FBW7_2 320 327 PF00400 0.483
DEG_SPOP_SBC_1 490 494 PF00917 0.477
DOC_CYCLIN_RxL_1 820 830 PF00134 0.492
DOC_CYCLIN_yCln2_LP_2 460 466 PF00134 0.482
DOC_MAPK_DCC_7 456 466 PF00069 0.482
DOC_MAPK_gen_1 218 228 PF00069 0.545
DOC_MAPK_gen_1 822 829 PF00069 0.487
DOC_MAPK_gen_1 955 963 PF00069 0.502
DOC_MAPK_MEF2A_6 221 230 PF00069 0.517
DOC_MAPK_MEF2A_6 748 755 PF00069 0.470
DOC_MAPK_MEF2A_6 822 831 PF00069 0.470
DOC_MAPK_MEF2A_6 970 977 PF00069 0.428
DOC_MAPK_NFAT4_5 748 756 PF00069 0.470
DOC_MAPK_NFAT4_5 822 830 PF00069 0.470
DOC_MAPK_RevD_3 940 956 PF00069 0.170
DOC_PP1_RVXF_1 114 121 PF00149 0.548
DOC_PP1_RVXF_1 807 814 PF00149 0.488
DOC_PP2B_LxvP_1 161 164 PF13499 0.447
DOC_PP2B_LxvP_1 245 248 PF13499 0.467
DOC_USP7_MATH_1 1000 1004 PF00917 0.310
DOC_USP7_MATH_1 153 157 PF00917 0.323
DOC_USP7_MATH_1 364 368 PF00917 0.539
DOC_USP7_MATH_1 482 486 PF00917 0.524
DOC_USP7_MATH_1 557 561 PF00917 0.461
DOC_USP7_MATH_1 644 648 PF00917 0.564
DOC_USP7_MATH_1 791 795 PF00917 0.529
DOC_USP7_MATH_1 893 897 PF00917 0.483
DOC_USP7_UBL2_3 203 207 PF12436 0.675
DOC_WW_Pin1_4 239 244 PF00397 0.519
DOC_WW_Pin1_4 316 321 PF00397 0.463
DOC_WW_Pin1_4 848 853 PF00397 0.338
LIG_14-3-3_CanoR_1 470 475 PF00244 0.456
LIG_14-3-3_CanoR_1 54 59 PF00244 0.678
LIG_Actin_WH2_2 89 107 PF00022 0.543
LIG_AP2alpha_1 371 375 PF02296 0.483
LIG_APCC_ABBAyCdc20_2 1068 1074 PF00400 0.515
LIG_BIR_III_4 719 723 PF00653 0.548
LIG_BRCT_BRCA1_1 61 65 PF00533 0.591
LIG_BRCT_BRCA1_1 978 982 PF00533 0.347
LIG_CNOT1_NIM_1 368 377 PF04054 0.424
LIG_DLG_GKlike_1 470 477 PF00625 0.456
LIG_EVH1_2 129 133 PF00568 0.475
LIG_FHA_1 1012 1018 PF00498 0.400
LIG_FHA_1 173 179 PF00498 0.281
LIG_FHA_1 225 231 PF00498 0.468
LIG_FHA_1 27 33 PF00498 0.591
LIG_FHA_1 282 288 PF00498 0.484
LIG_FHA_1 393 399 PF00498 0.508
LIG_FHA_1 430 436 PF00498 0.461
LIG_FHA_1 624 630 PF00498 0.498
LIG_FHA_1 643 649 PF00498 0.482
LIG_FHA_1 853 859 PF00498 0.280
LIG_FHA_1 912 918 PF00498 0.334
LIG_FHA_2 130 136 PF00498 0.492
LIG_FHA_2 160 166 PF00498 0.465
LIG_FHA_2 288 294 PF00498 0.493
LIG_FHA_2 492 498 PF00498 0.548
LIG_FHA_2 527 533 PF00498 0.482
LIG_FHA_2 58 64 PF00498 0.673
LIG_FHA_2 707 713 PF00498 0.470
LIG_FHA_2 755 761 PF00498 0.554
LIG_GBD_Chelix_1 96 104 PF00786 0.267
LIG_IBAR_NPY_1 700 702 PF08397 0.398
LIG_KLC1_Yacidic_2 1069 1074 PF13176 0.515
LIG_LIR_Gen_1 179 189 PF02991 0.339
LIG_LIR_Gen_1 202 211 PF02991 0.687
LIG_LIR_Gen_1 34 43 PF02991 0.574
LIG_LIR_Gen_1 647 656 PF02991 0.523
LIG_LIR_Gen_1 830 841 PF02991 0.340
LIG_LIR_Gen_1 937 948 PF02991 0.311
LIG_LIR_Gen_1 979 988 PF02991 0.359
LIG_LIR_LC3C_4 242 247 PF02991 0.492
LIG_LIR_Nem_3 132 137 PF02991 0.466
LIG_LIR_Nem_3 179 184 PF02991 0.339
LIG_LIR_Nem_3 202 208 PF02991 0.602
LIG_LIR_Nem_3 22 28 PF02991 0.605
LIG_LIR_Nem_3 355 360 PF02991 0.448
LIG_LIR_Nem_3 367 371 PF02991 0.434
LIG_LIR_Nem_3 373 377 PF02991 0.417
LIG_LIR_Nem_3 647 653 PF02991 0.504
LIG_LIR_Nem_3 712 716 PF02991 0.477
LIG_LIR_Nem_3 801 807 PF02991 0.494
LIG_LIR_Nem_3 830 836 PF02991 0.340
LIG_LIR_Nem_3 937 943 PF02991 0.311
LIG_LIR_Nem_3 979 983 PF02991 0.300
LIG_NRBOX 346 352 PF00104 0.500
LIG_PCNA_TLS_4 369 376 PF02747 0.495
LIG_PCNA_yPIPBox_3 815 825 PF02747 0.470
LIG_Pex14_1 177 181 PF04695 0.339
LIG_Pex14_2 1033 1037 PF04695 0.630
LIG_Pex14_2 371 375 PF04695 0.483
LIG_Pex14_2 980 984 PF04695 0.344
LIG_PTB_Apo_2 697 704 PF02174 0.398
LIG_PTB_Apo_2 712 719 PF02174 0.521
LIG_PTB_Apo_2 776 783 PF02174 0.507
LIG_PTB_Phospho_1 697 703 PF10480 0.398
LIG_PTB_Phospho_1 712 718 PF10480 0.521
LIG_REV1ctd_RIR_1 117 125 PF16727 0.475
LIG_SH2_CRK 631 635 PF00017 0.532
LIG_SH2_CRK 909 913 PF00017 0.331
LIG_SH2_GRB2like 594 597 PF00017 0.482
LIG_SH2_PTP2 833 836 PF00017 0.340
LIG_SH2_SRC 920 923 PF00017 0.367
LIG_SH2_STAP1 28 32 PF00017 0.726
LIG_SH2_STAP1 920 924 PF00017 0.367
LIG_SH2_STAT5 1072 1075 PF00017 0.515
LIG_SH2_STAT5 173 176 PF00017 0.291
LIG_SH2_STAT5 253 256 PF00017 0.467
LIG_SH2_STAT5 28 31 PF00017 0.572
LIG_SH2_STAT5 374 377 PF00017 0.503
LIG_SH2_STAT5 446 449 PF00017 0.492
LIG_SH2_STAT5 594 597 PF00017 0.503
LIG_SH2_STAT5 833 836 PF00017 0.340
LIG_SH3_3 1025 1031 PF00018 0.539
LIG_SH3_3 123 129 PF00018 0.582
LIG_SH3_3 160 166 PF00018 0.455
LIG_SH3_3 381 387 PF00018 0.461
LIG_SH3_3 451 457 PF00018 0.485
LIG_SH3_3 656 662 PF00018 0.497
LIG_SUMO_SIM_anti_2 186 192 PF11976 0.320
LIG_SUMO_SIM_anti_2 796 802 PF11976 0.504
LIG_SUMO_SIM_par_1 186 192 PF11976 0.317
LIG_SUMO_SIM_par_1 225 232 PF11976 0.476
LIG_SUMO_SIM_par_1 237 242 PF11976 0.449
LIG_SUMO_SIM_par_1 278 284 PF11976 0.469
LIG_SUMO_SIM_par_1 349 355 PF11976 0.467
LIG_SUMO_SIM_par_1 382 388 PF11976 0.463
LIG_SUMO_SIM_par_1 390 395 PF11976 0.465
LIG_SUMO_SIM_par_1 751 757 PF11976 0.488
LIG_SUMO_SIM_par_1 760 765 PF11976 0.451
LIG_SUMO_SIM_par_1 796 802 PF11976 0.496
LIG_SUMO_SIM_par_1 909 914 PF11976 0.279
LIG_TRAF2_1 324 327 PF00917 0.476
LIG_TRAF2_1 874 877 PF00917 0.351
LIG_TRAF2_1 878 881 PF00917 0.491
LIG_TYR_ITIM 372 377 PF00017 0.366
LIG_TYR_ITIM 629 634 PF00017 0.366
LIG_TYR_ITIM 831 836 PF00017 0.340
LIG_WRC_WIRS_1 977 982 PF05994 0.349
MOD_CDK_SPK_2 316 321 PF00069 0.206
MOD_CK1_1 103 109 PF00069 0.386
MOD_CK1_1 1055 1061 PF00069 0.476
MOD_CK1_1 16 22 PF00069 0.648
MOD_CK1_1 24 30 PF00069 0.582
MOD_CK1_1 264 270 PF00069 0.326
MOD_CK1_1 429 435 PF00069 0.313
MOD_CK1_1 851 857 PF00069 0.319
MOD_CK1_1 976 982 PF00069 0.336
MOD_CK2_1 1 7 PF00069 0.514
MOD_CK2_1 129 135 PF00069 0.406
MOD_CK2_1 349 355 PF00069 0.333
MOD_CK2_1 482 488 PF00069 0.343
MOD_CK2_1 491 497 PF00069 0.343
MOD_CK2_1 57 63 PF00069 0.654
MOD_CK2_1 754 760 PF00069 0.441
MOD_GlcNHglycan 105 108 PF01048 0.396
MOD_GlcNHglycan 1054 1057 PF01048 0.439
MOD_GlcNHglycan 210 215 PF01048 0.564
MOD_GlcNHglycan 275 278 PF01048 0.341
MOD_GlcNHglycan 3 6 PF01048 0.759
MOD_GlcNHglycan 466 469 PF01048 0.399
MOD_GlcNHglycan 565 568 PF01048 0.362
MOD_GlcNHglycan 785 788 PF01048 0.447
MOD_GlcNHglycan 793 796 PF01048 0.415
MOD_GlcNHglycan 970 973 PF01048 0.215
MOD_GSK3_1 1033 1040 PF00069 0.597
MOD_GSK3_1 188 195 PF00069 0.313
MOD_GSK3_1 206 213 PF00069 0.513
MOD_GSK3_1 224 231 PF00069 0.347
MOD_GSK3_1 283 290 PF00069 0.305
MOD_GSK3_1 316 323 PF00069 0.206
MOD_GSK3_1 422 429 PF00069 0.376
MOD_GSK3_1 762 769 PF00069 0.304
MOD_GSK3_1 832 839 PF00069 0.341
MOD_GSK3_1 847 854 PF00069 0.429
MOD_GSK3_1 872 879 PF00069 0.312
MOD_GSK3_1 96 103 PF00069 0.448
MOD_GSK3_1 996 1003 PF00069 0.395
MOD_LATS_1 579 585 PF00433 0.343
MOD_N-GLC_1 1093 1098 PF02516 0.608
MOD_N-GLC_1 171 176 PF02516 0.351
MOD_N-GLC_1 422 427 PF02516 0.421
MOD_N-GLC_1 483 488 PF02516 0.287
MOD_N-GLC_1 512 517 PF02516 0.284
MOD_N-GLC_1 623 628 PF02516 0.324
MOD_NEK2_1 1 6 PF00069 0.566
MOD_NEK2_1 100 105 PF00069 0.386
MOD_NEK2_1 1037 1042 PF00069 0.364
MOD_NEK2_1 1093 1098 PF00069 0.650
MOD_NEK2_1 159 164 PF00069 0.437
MOD_NEK2_1 252 257 PF00069 0.438
MOD_NEK2_1 283 288 PF00069 0.286
MOD_NEK2_1 311 316 PF00069 0.343
MOD_NEK2_1 392 397 PF00069 0.346
MOD_NEK2_1 398 403 PF00069 0.311
MOD_NEK2_1 43 48 PF00069 0.512
MOD_NEK2_1 706 711 PF00069 0.381
MOD_NEK2_1 740 745 PF00069 0.308
MOD_NEK2_1 754 759 PF00069 0.308
MOD_NEK2_1 827 832 PF00069 0.322
MOD_NEK2_1 840 845 PF00069 0.324
MOD_NEK2_1 899 904 PF00069 0.324
MOD_NEK2_1 911 916 PF00069 0.274
MOD_NEK2_1 973 978 PF00069 0.348
MOD_NEK2_1 996 1001 PF00069 0.276
MOD_NEK2_2 674 679 PF00069 0.309
MOD_NEK2_2 893 898 PF00069 0.161
MOD_PIKK_1 398 404 PF00454 0.324
MOD_PIKK_1 422 428 PF00454 0.394
MOD_PIKK_1 433 439 PF00454 0.339
MOD_PIKK_1 740 746 PF00454 0.324
MOD_PKA_1 273 279 PF00069 0.408
MOD_PKA_1 49 55 PF00069 0.430
MOD_PKA_1 563 569 PF00069 0.324
MOD_PKA_2 1 7 PF00069 0.660
MOD_PKA_2 49 55 PF00069 0.690
MOD_PKA_2 563 569 PF00069 0.343
MOD_PKB_1 549 557 PF00069 0.449
MOD_Plk_1 1033 1039 PF00069 0.355
MOD_Plk_1 1093 1099 PF00069 0.538
MOD_Plk_1 224 230 PF00069 0.354
MOD_Plk_1 261 267 PF00069 0.308
MOD_Plk_1 302 308 PF00069 0.333
MOD_Plk_1 422 428 PF00069 0.414
MOD_Plk_1 623 629 PF00069 0.327
MOD_Plk_1 933 939 PF00069 0.305
MOD_Plk_2-3 109 115 PF00069 0.395
MOD_Plk_2-3 876 882 PF00069 0.371
MOD_Plk_4 1037 1043 PF00069 0.506
MOD_Plk_4 1111 1117 PF00069 0.682
MOD_Plk_4 129 135 PF00069 0.319
MOD_Plk_4 153 159 PF00069 0.296
MOD_Plk_4 183 189 PF00069 0.323
MOD_Plk_4 255 261 PF00069 0.326
MOD_Plk_4 283 289 PF00069 0.330
MOD_Plk_4 349 355 PF00069 0.351
MOD_Plk_4 438 444 PF00069 0.308
MOD_Plk_4 54 60 PF00069 0.694
MOD_Plk_4 572 578 PF00069 0.411
MOD_Plk_4 644 650 PF00069 0.409
MOD_Plk_4 735 741 PF00069 0.447
MOD_Plk_4 836 842 PF00069 0.318
MOD_Plk_4 899 905 PF00069 0.260
MOD_Plk_4 934 940 PF00069 0.306
MOD_Plk_4 944 950 PF00069 0.294
MOD_ProDKin_1 239 245 PF00069 0.393
MOD_ProDKin_1 316 322 PF00069 0.314
MOD_ProDKin_1 848 854 PF00069 0.313
MOD_SUMO_rev_2 1040 1049 PF00179 0.440
MOD_SUMO_rev_2 560 565 PF00179 0.318
TRG_DiLeu_BaEn_1 1111 1116 PF01217 0.681
TRG_DiLeu_BaEn_1 331 336 PF01217 0.390
TRG_DiLeu_BaEn_1 572 577 PF01217 0.340
TRG_DiLeu_BaEn_4 1111 1117 PF01217 0.421
TRG_DiLeu_BaLyEn_6 1021 1026 PF01217 0.378
TRG_DiLeu_BaLyEn_6 144 149 PF01217 0.332
TRG_ENDOCYTIC_2 368 371 PF00928 0.343
TRG_ENDOCYTIC_2 374 377 PF00928 0.330
TRG_ENDOCYTIC_2 446 449 PF00928 0.329
TRG_ENDOCYTIC_2 631 634 PF00928 0.315
TRG_ENDOCYTIC_2 703 706 PF00928 0.317
TRG_ENDOCYTIC_2 833 836 PF00928 0.340
TRG_ENDOCYTIC_2 87 90 PF00928 0.461
TRG_ENDOCYTIC_2 909 912 PF00928 0.331
TRG_ENDOCYTIC_2 920 923 PF00928 0.359
TRG_ENDOCYTIC_2 958 961 PF00928 0.332
TRG_ER_diArg_1 1075 1078 PF00400 0.592
TRG_ER_diArg_1 1079 1082 PF00400 0.581
TRG_ER_diArg_1 1102 1105 PF00400 0.561
TRG_ER_diArg_1 116 118 PF00400 0.316
TRG_ER_diArg_1 217 220 PF00400 0.458
TRG_ER_diArg_1 412 414 PF00400 0.463
TRG_ER_diArg_1 47 50 PF00400 0.712
TRG_ER_diArg_1 562 565 PF00400 0.397
TRG_ER_diArg_1 609 612 PF00400 0.398
TRG_NES_CRM1_1 646 658 PF08389 0.386
TRG_NES_CRM1_1 744 760 PF08389 0.339
TRG_NLS_MonoExtN_4 272 277 PF00514 0.366
TRG_Pf-PMV_PEXEL_1 1082 1087 PF00026 0.508
TRG_Pf-PMV_PEXEL_1 309 313 PF00026 0.343
TRG_Pf-PMV_PEXEL_1 358 363 PF00026 0.357
TRG_Pf-PMV_PEXEL_1 475 479 PF00026 0.388
TRG_Pf-PMV_PEXEL_1 714 719 PF00026 0.337
TRG_Pf-PMV_PEXEL_1 955 959 PF00026 0.314

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 28% 100%
A0A0N1HWG6 Leptomonas seymouri 41% 100%
A0A0N1PFH3 Leptomonas seymouri 27% 92%
A0A0S4J5A1 Bodo saltans 29% 100%
A0A0S4J6U4 Bodo saltans 38% 100%
A0A0S4JA92 Bodo saltans 42% 100%
A0A0S4JRV4 Bodo saltans 41% 100%
A0A0S4KIG5 Bodo saltans 28% 100%
A0A0S4KNQ6 Bodo saltans 63% 100%
A0A1X0NNY6 Trypanosomatidae 29% 100%
A0A1X0NPD9 Trypanosomatidae 65% 100%
A0A1X0NTI6 Trypanosomatidae 39% 99%
A0A1X0P0Y8 Trypanosomatidae 36% 100%
A0A1X0P689 Trypanosomatidae 27% 100%
A0A381MFJ0 Leishmania infantum 24% 100%
A0A3R7KM63 Trypanosoma rangeli 66% 100%
A0A3R7MRX8 Trypanosoma rangeli 29% 100%
A0A3S5H5Y9 Leishmania donovani 87% 100%
A0A3S5ISK9 Trypanosoma rangeli 36% 100%
A0A3S7WPW0 Leishmania donovani 96% 100%
A0A3S7WUG2 Leishmania donovani 39% 99%
A0A3S7WV61 Leishmania donovani 23% 100%
A0A3S7WV68 Leishmania donovani 24% 100%
A0A3S7X978 Leishmania donovani 27% 100%
A0A422NTS7 Trypanosoma rangeli 28% 100%
A0A451EJU6 Leishmania donovani 27% 100%
A0R3Y2 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) 24% 100%
A2VDL6 Bos taurus 28% 100%
A4H3S2 Leishmania braziliensis 26% 100%
A4H514 Leishmania braziliensis 81% 99%
A4H903 Leishmania braziliensis 39% 100%
A4H9Q5 Leishmania braziliensis 23% 100%
A4HMM8 Leishmania braziliensis 28% 100%
A4HRZ6 Leishmania infantum 27% 100%
A4HT82 Leishmania infantum 97% 100%
A4HTF0 Leishmania infantum 94% 100%
A4HXD4 Leishmania infantum 39% 99%
A4HY23 Leishmania infantum 24% 100%
A4IBA6 Leishmania infantum 27% 100%
A7L9Z8 Mus musculus 28% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 59% 100%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A4V8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A564 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
D0ZTB2 Salmonella typhimurium (strain 14028s / SGSC 2262) 25% 100%
D2WKD8 Sus scrofa 28% 100%
D3K0R6 Bos taurus 36% 93%
E9AF31 Leishmania major 27% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AL76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
E9AR29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 99%
E9ART6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 23% 100%
E9B686 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 91%
G5E829 Mus musculus 39% 92%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 37% 79%
O14022 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 20% 100%
O14983 Homo sapiens 29% 100%
O22218 Arabidopsis thaliana 36% 100%
O23087 Arabidopsis thaliana 27% 100%
O34431 Bacillus subtilis (strain 168) 29% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 28% 100%
O46674 Canis lupus familiaris 28% 100%
O55143 Mus musculus 27% 100%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
O64806 Arabidopsis thaliana 37% 100%
O75185 Homo sapiens 27% 100%
O77696 Sus scrofa 28% 100%
O81108 Arabidopsis thaliana 37% 100%
P04074 Ovis aries 26% 100%
P04191 Oryctolagus cuniculus 29% 100%
P05023 Homo sapiens 26% 100%
P05024 Sus scrofa 26% 100%
P05025 Tetronarce californica 27% 100%
P05030 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 24% 100%
P06685 Rattus norvegicus 26% 100%
P06686 Rattus norvegicus 29% 100%
P06687 Rattus norvegicus 27% 100%
P09572 Gallus gallus 26% 100%
P09626 Rattus norvegicus 27% 100%
P0ABB8 Escherichia coli (strain K12) 24% 100%
P0ABB9 Escherichia coli O157:H7 24% 100%
P11505 Rattus norvegicus 39% 92%
P11506 Rattus norvegicus 39% 90%
P11507 Rattus norvegicus 28% 100%
P11607 Sus scrofa 28% 100%
P11718 Leishmania donovani 23% 100%
P12522 Leishmania donovani 24% 100%
P13585 Gallus gallus 28% 100%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 100%
P13587 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
P13607 Drosophila melanogaster 27% 100%
P13637 Homo sapiens 27% 100%
P16615 Homo sapiens 28% 100%
P17326 Artemia franciscana 28% 100%
P18596 Rattus norvegicus 29% 100%
P18907 Equus caballus 26% 100%
P19156 Sus scrofa 28% 100%
P20020 Homo sapiens 39% 92%
P20431 Arabidopsis thaliana 23% 100%
P20647 Oryctolagus cuniculus 28% 100%
P20648 Homo sapiens 27% 100%
P22036 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 24% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 100%
P22700 Drosophila melanogaster 26% 100%
P23220 Sus scrofa 39% 92%
P23634 Homo sapiens 38% 90%
P24797 Gallus gallus 27% 100%
P24798 Gallus gallus 27% 100%
P25489 Catostomus commersonii 27% 100%
P27112 Oryctolagus cuniculus 27% 100%
P28774 Artemia franciscana 29% 100%
P30714 Rhinella marina 26% 100%
P35315 Trypanosoma brucei brucei 30% 100%
P35316 Artemia franciscana 26% 100%
P35317 Hydra vulgaris 28% 100%
P36640 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 25% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 31% 100%
P37367 Synechocystis sp. (strain PCC 6803 / Kazusa) 27% 100%
P38929 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 33% 95%
P47317 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 27% 100%
P49380 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 25% 100%
P50993 Homo sapiens 28% 100%
P50996 Canis lupus familiaris 27% 100%
P50997 Canis lupus familiaris 26% 100%
P54209 Dunaliella bioculata 30% 100%
P54211 Dunaliella bioculata 24% 99%
P54678 Dictyostelium discoideum 39% 100%
P54707 Homo sapiens 27% 100%
P54708 Rattus norvegicus 26% 100%
P57709 Bos taurus 27% 100%
P58312 Oreochromis mossambicus 26% 100%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 30% 100%
P70083 Makaira nigricans 27% 100%
P78036 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 28% 100%
P92939 Arabidopsis thaliana 28% 100%
P98194 Homo sapiens 27% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 30% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 30% 100%
Q00779 Felis catus 28% 100%
Q00804 Oryctolagus cuniculus 38% 92%
Q01814 Homo sapiens 39% 90%
Q01896 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
Q03669 Gallus gallus 28% 100%
Q07421 Ajellomyces capsulatus 24% 100%
Q08436 Nicotiana plumbaginifolia 23% 100%
Q08DA1 Bos taurus 26% 100%
Q0VCY0 Bos taurus 29% 100%
Q12691 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
Q16720 Homo sapiens 35% 92%
Q21286 Caenorhabditis elegans 23% 93%
Q292Q0 Drosophila pseudoobscura pseudoobscura 26% 100%
Q2QMX9 Oryza sativa subsp. japonica 36% 100%
Q2QY12 Oryza sativa subsp. japonica 37% 100%
Q2RAS0 Oryza sativa subsp. japonica 37% 100%
Q37145 Arabidopsis thaliana 37% 100%
Q42883 Solanum lycopersicum 27% 100%
Q4QDN7 Leishmania major 23% 100%
Q4QDN8 Leishmania major 23% 100%
Q4QED4 Leishmania major 40% 100%
Q4QIM8 Leishmania major 88% 100%
Q4VNC1 Homo sapiens 21% 94%
Q58623 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 25% 100%
Q5R5K5 Pongo abelii 27% 100%
Q5RCD8 Pongo abelii 28% 100%
Q5RDR3 Pongo abelii 26% 100%
Q64392 Cavia porcellus 28% 100%
Q64436 Mus musculus 27% 100%
Q64518 Mus musculus 28% 100%
Q64541 Rattus norvegicus 28% 100%
Q64542 Rattus norvegicus 38% 93%
Q64566 Rattus norvegicus 26% 100%
Q64568 Rattus norvegicus 37% 89%
Q64578 Rattus norvegicus 28% 100%
Q65X71 Oryza sativa subsp. japonica 35% 100%
Q6ATV4 Oryza sativa subsp. japonica 37% 100%
Q6PIC6 Mus musculus 27% 100%
Q6PIE5 Mus musculus 29% 100%
Q6Q477 Mus musculus 37% 93%
Q6RWA9 Taenia solium 28% 100%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 28% 100%
Q7PPA5 Anopheles gambiae 27% 100%
Q7X8B5 Oryza sativa subsp. japonica 37% 100%
Q7XEK4 Oryza sativa subsp. japonica 35% 100%
Q80XR2 Mus musculus 27% 100%
Q8R429 Mus musculus 28% 100%
Q8R4C1 Rattus norvegicus 28% 100%
Q8RUN1 Oryza sativa subsp. japonica 37% 100%
Q8VDN2 Mus musculus 26% 100%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 31% 100%
Q92030 Anguilla anguilla 27% 100%
Q92105 Pelophylax lessonae 29% 100%
Q92123 Xenopus laevis 27% 100%
Q92126 Xenopus laevis 27% 100%
Q93084 Homo sapiens 29% 100%
Q95Z93 Leishmania major 27% 100%
Q98SH2 Gallus gallus 37% 93%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 28% 100%
Q9CTG6 Mus musculus 23% 96%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 38% 87%
Q9LF79 Arabidopsis thaliana 36% 100%
Q9LIK7 Arabidopsis thaliana 35% 100%
Q9LU41 Arabidopsis thaliana 35% 100%
Q9LV11 Arabidopsis thaliana 24% 100%
Q9LY32 Arabidopsis thaliana 22% 100%
Q9LY77 Arabidopsis thaliana 37% 100%
Q9M2A0 Arabidopsis thaliana 23% 100%
Q9M2L4 Arabidopsis thaliana 38% 100%
Q9N0Z6 Oryctolagus cuniculus 26% 100%
Q9NQ11 Homo sapiens 23% 95%
Q9R0K7 Mus musculus 37% 93%
Q9SJB3 Arabidopsis thaliana 22% 100%
Q9SU58 Arabidopsis thaliana 23% 100%
Q9SY55 Arabidopsis thaliana 28% 100%
Q9SZR1 Arabidopsis thaliana 36% 100%
Q9WV27 Mus musculus 28% 100%
Q9XES1 Arabidopsis thaliana 28% 100%
Q9YGL9 Gallus gallus 27% 100%
Q9YH26 Oreochromis mossambicus 28% 100%
Q9Z1W8 Mus musculus 28% 100%
V5B873 Trypanosoma cruzi 64% 100%
V5BHZ2 Trypanosoma cruzi 27% 100%
V5BLM1 Trypanosoma cruzi 29% 100%
V5BPC6 Trypanosoma cruzi 36% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS