Putative Qa-SNARE protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Qa-SNARE protein, putative

Species:

Leishmania major

UniProt:

Q4QIM4_LEIMA

TriTrypDb:

LmjF.07.0670 , LMJLV39_070013100 , LMJSD75_070013200

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

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Expansion

Sequence features

Q4QIM4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIM4

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	114	118	PF00656	0.418
CLV_NRD_NRD_1	164	166	PF00675	0.629
DEG_Nend_UBRbox_1	1	4	PF02207	0.786
DEG_SIAH_1	57	65	PF03145	0.603
DEG_SPOP_SBC_1	69	73	PF00917	0.640
DOC_USP7_MATH_1	42	46	PF00917	0.762
DOC_USP7_MATH_1	64	68	PF00917	0.628
DOC_USP7_UBL2_3	162	166	PF12436	0.372
LIG_APCC_ABBA_1	135	140	PF00400	0.567
LIG_APCC_ABBAyCdc20_2	134	140	PF00400	0.569

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Y0	Leptomonas seymouri	68%	100%
A0A0S4J4H4	Bodo saltans	38%	100%
A0A3R7K1F7	Trypanosoma rangeli	42%	100%
A0A3S5H5Z1	Leishmania donovani	90%	99%
A4H518	Leishmania braziliensis	77%	100%
A4HT91	Leishmania infantum	90%	99%
E9AL80	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	98%
V5B8I6	Trypanosoma cruzi	42%	100%

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