Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

chaperone protein DnaJ, putative

Species:

Leishmania major

UniProt:

Q4QIL1_LEIMA

TriTrypDb:

LmjF.07.0780 , LMJLV39_070014500 , LMJSD75_070014600

Length:

299

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

Q4QIL1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIL1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	160	162	PF00675	0.526
CLV_NRD_NRD_1	206	208	PF00675	0.492
CLV_NRD_NRD_1	213	215	PF00675	0.471
CLV_NRD_NRD_1	220	222	PF00675	0.459
CLV_NRD_NRD_1	294	296	PF00675	0.550
CLV_PCSK_FUR_1	158	162	PF00082	0.528
CLV_PCSK_KEX2_1	160	162	PF00082	0.463
CLV_PCSK_KEX2_1	193	195	PF00082	0.561
CLV_PCSK_KEX2_1	212	214	PF00082	0.348
CLV_PCSK_KEX2_1	220	222	PF00082	0.487
CLV_PCSK_PC1ET2_1	193	195	PF00082	0.545
CLV_PCSK_SKI1_1	190	194	PF00082	0.474
CLV_PCSK_SKI1_1	288	292	PF00082	0.482
DEG_Nend_Nbox_1	1	3	PF02207	0.506
DEG_SPOP_SBC_1	226	230	PF00917	0.653
DOC_ANK_TNKS_1	58	65	PF00023	0.440
DOC_PP4_FxxP_1	203	206	PF00568	0.666
DOC_PP4_FxxP_1	60	63	PF00568	0.509
DOC_USP7_MATH_1	135	139	PF00917	0.695
DOC_USP7_MATH_1	226	230	PF00917	0.673
DOC_USP7_MATH_1	256	260	PF00917	0.760
DOC_USP7_MATH_1	267	271	PF00917	0.593
DOC_USP7_MATH_1	276	280	PF00917	0.632
DOC_USP7_MATH_1	42	46	PF00917	0.550
DOC_USP7_MATH_1	84	88	PF00917	0.658
DOC_WW_Pin1_4	145	150	PF00397	0.693
DOC_WW_Pin1_4	230	235	PF00397	0.755
DOC_WW_Pin1_4	250	255	PF00397	0.641
DOC_WW_Pin1_4	44	49	PF00397	0.470
LIG_14-3-3_CanoR_1	227	236	PF00244	0.734
LIG_14-3-3_CanoR_1	46	52	PF00244	0.484
LIG_14-3-3_CterR_2	295	299	PF00244	0.771
LIG_BRCT_BRCA1_1	34	38	PF00533	0.572
LIG_BRCT_BRCA1_1	77	81	PF00533	0.498
LIG_deltaCOP1_diTrp_1	90	97	PF00928	0.652
LIG_EH_1	40	44	PF12763	0.560
LIG_FHA_1	77	83	PF00498	0.498
LIG_LIR_Gen_1	50	60	PF02991	0.340
LIG_LIR_Nem_3	47	52	PF02991	0.459
LIG_RPA_C_Fungi	156	168	PF08784	0.413
LIG_RPA_C_Fungi	215	227	PF08784	0.521
LIG_SH2_CRK	52	56	PF00017	0.409
LIG_SH2_GRB2like	25	28	PF00017	0.729
LIG_SH2_NCK_1	52	56	PF00017	0.664
LIG_SH2_SRC	154	157	PF00017	0.577
LIG_SH2_STAT3	156	159	PF00017	0.668
LIG_SH2_STAT3	5	8	PF00017	0.712
LIG_SH2_STAT5	144	147	PF00017	0.734
LIG_SH2_STAT5	74	77	PF00017	0.405
LIG_SH3_3	259	265	PF00018	0.776
LIG_SH3_3	270	276	PF00018	0.459
LIG_TRAF2_1	167	170	PF00917	0.432
LIG_TRAF2_1	279	282	PF00917	0.625
LIG_TYR_ITIM	72	77	PF00017	0.498
LIG_UBA3_1	290	296	PF00899	0.706
MOD_CDK_SPxxK_3	145	152	PF00069	0.699
MOD_CK1_1	138	144	PF00069	0.654
MOD_CK1_1	228	234	PF00069	0.721
MOD_CK1_1	47	53	PF00069	0.592
MOD_CK2_1	226	232	PF00069	0.759
MOD_CK2_1	276	282	PF00069	0.720
MOD_GlcNHglycan	197	201	PF01048	0.612
MOD_GlcNHglycan	258	262	PF01048	0.693
MOD_GlcNHglycan	34	37	PF01048	0.705
MOD_GSK3_1	226	233	PF00069	0.559
MOD_LATS_1	30	36	PF00433	0.729
MOD_N-GLC_1	267	272	PF02516	0.777
MOD_NEK2_1	225	230	PF00069	0.499
MOD_NEK2_1	75	80	PF00069	0.425
MOD_NEK2_1	99	104	PF00069	0.660
MOD_PKA_1	220	226	PF00069	0.560
MOD_PKA_2	220	226	PF00069	0.624
MOD_PKA_2	97	103	PF00069	0.633
MOD_Plk_1	267	273	PF00069	0.720
MOD_Plk_4	268	274	PF00069	0.776
MOD_Plk_4	62	68	PF00069	0.473
MOD_Plk_4	76	82	PF00069	0.307
MOD_ProDKin_1	145	151	PF00069	0.612
MOD_ProDKin_1	230	236	PF00069	0.708
MOD_ProDKin_1	250	256	PF00069	0.546
MOD_ProDKin_1	44	50	PF00069	0.578
TRG_ENDOCYTIC_2	52	55	PF00928	0.406
TRG_ENDOCYTIC_2	74	77	PF00928	0.405
TRG_ER_diArg_1	139	142	PF00400	0.661
TRG_ER_diArg_1	158	161	PF00400	0.671
TRG_ER_diArg_1	212	214	PF00400	0.612
TRG_ER_diArg_1	57	60	PF00400	0.658

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KL95	Bodo saltans	38%	80%
A0A3S7WPX5	Leishmania donovani	91%	98%
A4H530	Leishmania braziliensis	73%	68%
E9AL93	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%