UBA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIL0_LEIMA

TriTrypDb:

LmjF.07.0790 , LMJLV39_070014600 , LMJSD75_070014700

Length:

292

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIL0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIL0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.712
CLV_NRD_NRD_1	109	111	PF00675	0.695
CLV_NRD_NRD_1	187	189	PF00675	0.723
CLV_NRD_NRD_1	275	277	PF00675	0.595
CLV_PCSK_KEX2_1	104	106	PF00082	0.725
CLV_PCSK_KEX2_1	111	113	PF00082	0.684
CLV_PCSK_KEX2_1	187	189	PF00082	0.723
CLV_PCSK_KEX2_1	21	23	PF00082	0.549
CLV_PCSK_KEX2_1	275	277	PF00082	0.595
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.697
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.549
DEG_Nend_UBRbox_4	1	3	PF02207	0.667
DOC_CKS1_1	159	164	PF01111	0.766
DOC_MAPK_gen_1	238	247	PF00069	0.703
DOC_PP2B_LxvP_1	5	8	PF13499	0.732
DOC_PP2B_LxvP_1	70	73	PF13499	0.738
DOC_USP7_MATH_1	133	137	PF00917	0.625
DOC_USP7_MATH_1	225	229	PF00917	0.777
DOC_WW_Pin1_4	129	134	PF00397	0.747
DOC_WW_Pin1_4	158	163	PF00397	0.654
DOC_WW_Pin1_4	286	291	PF00397	0.750
LIG_14-3-3_CanoR_1	170	175	PF00244	0.710
LIG_14-3-3_CanoR_1	240	247	PF00244	0.639
LIG_BIR_III_4	97	101	PF00653	0.614
LIG_CaM_IQ_9	180	195	PF13499	0.657
LIG_EVH1_1	5	9	PF00568	0.739
LIG_FHA_1	159	165	PF00498	0.661
LIG_FHA_1	181	187	PF00498	0.666
LIG_FHA_1	221	227	PF00498	0.776
LIG_FHA_1	45	51	PF00498	0.715
LIG_FHA_2	146	152	PF00498	0.755
LIG_FHA_2	202	208	PF00498	0.664
LIG_GBD_Chelix_1	254	262	PF00786	0.582
LIG_Integrin_RGD_1	190	192	PF01839	0.498
LIG_PCNA_yPIPBox_3	35	45	PF02747	0.598
LIG_SH2_SRC	280	283	PF00017	0.595
LIG_SH2_STAT5	280	283	PF00017	0.536
LIG_SH3_3	156	162	PF00018	0.785
LIG_SH3_3	3	9	PF00018	0.748
LIG_SUMO_SIM_anti_2	251	257	PF11976	0.679
MOD_CK1_1	158	164	PF00069	0.726
MOD_CK1_1	166	172	PF00069	0.605
MOD_CK1_1	211	217	PF00069	0.817
MOD_CK1_1	271	277	PF00069	0.653
MOD_CK2_1	141	147	PF00069	0.756
MOD_CK2_1	201	207	PF00069	0.733
MOD_CK2_1	215	221	PF00069	0.615
MOD_CK2_1	58	64	PF00069	0.575
MOD_GlcNHglycan	135	138	PF01048	0.702
MOD_GlcNHglycan	143	146	PF01048	0.614
MOD_GlcNHglycan	218	221	PF01048	0.790
MOD_GlcNHglycan	247	250	PF01048	0.619
MOD_GlcNHglycan	264	268	PF01048	0.630
MOD_GlcNHglycan	60	63	PF01048	0.618
MOD_GSK3_1	129	136	PF00069	0.660
MOD_GSK3_1	141	148	PF00069	0.671
MOD_GSK3_1	151	158	PF00069	0.638
MOD_GSK3_1	166	173	PF00069	0.712
MOD_GSK3_1	207	214	PF00069	0.719
MOD_GSK3_1	216	223	PF00069	0.675
MOD_N-GLC_1	25	30	PF02516	0.655
MOD_NEK2_1	245	250	PF00069	0.629
MOD_NEK2_1	44	49	PF00069	0.621
MOD_NEK2_1	58	63	PF00069	0.577
MOD_PIKK_1	180	186	PF00454	0.707
MOD_PKA_2	274	280	PF00069	0.651
MOD_Plk_1	268	274	PF00069	0.667
MOD_ProDKin_1	129	135	PF00069	0.747
MOD_ProDKin_1	158	164	PF00069	0.651
MOD_ProDKin_1	286	292	PF00069	0.763
TRG_ER_diArg_1	104	106	PF00400	0.816
TRG_ER_diArg_1	109	112	PF00400	0.700
TRG_ER_diArg_1	186	188	PF00400	0.725
TRG_ER_diArg_1	275	278	PF00400	0.597
TRG_NLS_MonoExtN_4	109	114	PF00514	0.704
TRG_Pf-PMV_PEXEL_1	197	202	PF00026	0.665
TRG_Pf-PMV_PEXEL_1	22	27	PF00026	0.669
TRG_Pf-PMV_PEXEL_1	256	260	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDZ9	Leptomonas seymouri	38%	95%
A0A3S7WPY2	Leishmania donovani	89%	100%
A4H531	Leishmania braziliensis	68%	100%
A4HTA5	Leishmania infantum	89%	90%
E9AL94	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%