Cytochrome b5-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cytochrome b5-like protein

Species:

Leishmania major

UniProt:

Q4QIK6_LEIMA

TriTrypDb:

LmjF.07.0810 , LMJLV39_070015000 , LMJSD75_070015100

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QIK6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIK6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0020037	heme binding	4	2
GO:0046906	tetrapyrrole binding	3	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	48	50	PF00082	0.549
CLV_PCSK_PC1ET2_1	48	50	PF00082	0.549
CLV_PCSK_SKI1_1	39	43	PF00082	0.549
CLV_PCSK_SKI1_1	48	52	PF00082	0.392
DOC_PP1_RVXF_1	46	53	PF00149	0.549
DOC_PP2B_LxvP_1	35	38	PF13499	0.549
DOC_USP7_UBL2_3	19	23	PF12436	0.549
LIG_BIR_II_1	1	5	PF00653	0.797
MOD_CK2_1	4	10	PF00069	0.769
MOD_Cter_Amidation	46	49	PF01082	0.549
MOD_GlcNHglycan	45	48	PF01048	0.549
MOD_Plk_1	56	62	PF00069	0.549
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q9HFV1	RHIST	40%	48%
Q9P5L0	NEUCR	42%	45%
Q9V4N3	DROME	39%	47%