Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QIJ1_LEIMA

TriTrypDb:

LmjF.07.0960 , LMJLV39_070016700 , LMJSD75_070017000

Length:

1134

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIJ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIJ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	706	710	PF00656	0.711
CLV_C14_Caspase3-7	911	915	PF00656	0.710
CLV_NRD_NRD_1	117	119	PF00675	0.549
CLV_NRD_NRD_1	149	151	PF00675	0.472
CLV_NRD_NRD_1	158	160	PF00675	0.456
CLV_NRD_NRD_1	223	225	PF00675	0.535
CLV_NRD_NRD_1	295	297	PF00675	0.557
CLV_NRD_NRD_1	341	343	PF00675	0.492
CLV_NRD_NRD_1	421	423	PF00675	0.461
CLV_NRD_NRD_1	463	465	PF00675	0.500
CLV_NRD_NRD_1	521	523	PF00675	0.519
CLV_NRD_NRD_1	532	534	PF00675	0.466
CLV_NRD_NRD_1	546	548	PF00675	0.428
CLV_NRD_NRD_1	599	601	PF00675	0.413
CLV_NRD_NRD_1	616	618	PF00675	0.427
CLV_NRD_NRD_1	65	67	PF00675	0.460
CLV_NRD_NRD_1	680	682	PF00675	0.556
CLV_NRD_NRD_1	727	729	PF00675	0.516
CLV_NRD_NRD_1	93	95	PF00675	0.625
CLV_NRD_NRD_1	939	941	PF00675	0.598
CLV_PCSK_FUR_1	115	119	PF00082	0.422
CLV_PCSK_KEX2_1	117	119	PF00082	0.417
CLV_PCSK_KEX2_1	148	150	PF00082	0.469
CLV_PCSK_KEX2_1	157	159	PF00082	0.462
CLV_PCSK_KEX2_1	223	225	PF00082	0.538
CLV_PCSK_KEX2_1	321	323	PF00082	0.486
CLV_PCSK_KEX2_1	341	343	PF00082	0.339
CLV_PCSK_KEX2_1	420	422	PF00082	0.471
CLV_PCSK_KEX2_1	463	465	PF00082	0.500
CLV_PCSK_KEX2_1	521	523	PF00082	0.518
CLV_PCSK_KEX2_1	546	548	PF00082	0.487
CLV_PCSK_KEX2_1	598	600	PF00082	0.387
CLV_PCSK_KEX2_1	616	618	PF00082	0.426
CLV_PCSK_KEX2_1	65	67	PF00082	0.459
CLV_PCSK_KEX2_1	680	682	PF00082	0.568
CLV_PCSK_KEX2_1	726	728	PF00082	0.484
CLV_PCSK_KEX2_1	92	94	PF00082	0.617
CLV_PCSK_KEX2_1	939	941	PF00082	0.598
CLV_PCSK_PC1ET2_1	321	323	PF00082	0.567
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.549
CLV_PCSK_PC1ET2_1	598	600	PF00082	0.416
CLV_PCSK_PC1ET2_1	92	94	PF00082	0.485
CLV_PCSK_PC7_1	459	465	PF00082	0.558
CLV_PCSK_PC7_1	595	601	PF00082	0.376
CLV_PCSK_PC7_1	612	618	PF00082	0.391
CLV_PCSK_PC7_1	89	95	PF00082	0.538
CLV_PCSK_SKI1_1	381	385	PF00082	0.557
CLV_PCSK_SKI1_1	489	493	PF00082	0.542
CLV_PCSK_SKI1_1	533	537	PF00082	0.528
CLV_PCSK_SKI1_1	595	599	PF00082	0.574
DEG_APCC_DBOX_1	267	275	PF00400	0.457
DEG_APCC_DBOX_1	633	641	PF00400	0.507
DEG_APCC_DBOX_1	725	733	PF00400	0.543
DEG_APCC_DBOX_1	781	789	PF00400	0.605
DEG_COP1_1	946	954	PF00400	0.664
DEG_SPOP_SBC_1	1074	1078	PF00917	0.603
DEG_SPOP_SBC_1	49	53	PF00917	0.460
DOC_ANK_TNKS_1	938	945	PF00023	0.625
DOC_CKS1_1	901	906	PF01111	0.516
DOC_CKS1_1	951	956	PF01111	0.634
DOC_CKS1_1	996	1001	PF01111	0.582
DOC_CYCLIN_RxL_1	530	541	PF00134	0.654
DOC_CYCLIN_yCln2_LP_2	1001	1007	PF00134	0.774
DOC_CYCLIN_yCln2_LP_2	1094	1100	PF00134	0.573
DOC_CYCLIN_yCln2_LP_2	788	794	PF00134	0.550
DOC_CYCLIN_yCln2_LP_2	922	928	PF00134	0.633
DOC_MAPK_DCC_7	1064	1072	PF00069	0.610
DOC_MAPK_gen_1	779	788	PF00069	0.656
DOC_MAPK_HePTP_8	937	949	PF00069	0.600
DOC_MAPK_MEF2A_6	1064	1072	PF00069	0.610
DOC_MAPK_MEF2A_6	894	902	PF00069	0.644
DOC_MAPK_MEF2A_6	940	949	PF00069	0.706
DOC_PP2B_LxvP_1	10	13	PF13499	0.442
DOC_PP2B_LxvP_1	1001	1004	PF13499	0.776
DOC_PP2B_LxvP_1	1094	1097	PF13499	0.567
DOC_PP2B_LxvP_1	501	504	PF13499	0.499
DOC_PP2B_LxvP_1	788	791	PF13499	0.592
DOC_PP2B_LxvP_1	922	925	PF13499	0.644
DOC_PP4_FxxP_1	18	21	PF00568	0.468
DOC_USP7_MATH_1	1030	1034	PF00917	0.614
DOC_USP7_MATH_1	1053	1057	PF00917	0.752
DOC_USP7_MATH_1	1063	1067	PF00917	0.679
DOC_USP7_MATH_1	1073	1077	PF00917	0.610
DOC_USP7_MATH_1	1080	1084	PF00917	0.628
DOC_USP7_MATH_1	11	15	PF00917	0.496
DOC_USP7_MATH_1	1111	1115	PF00917	0.696
DOC_USP7_MATH_1	216	220	PF00917	0.493
DOC_USP7_MATH_1	257	261	PF00917	0.555
DOC_USP7_MATH_1	27	31	PF00917	0.581
DOC_USP7_MATH_1	520	524	PF00917	0.554
DOC_USP7_MATH_1	542	546	PF00917	0.435
DOC_USP7_MATH_1	55	59	PF00917	0.614
DOC_USP7_MATH_1	840	844	PF00917	0.642
DOC_USP7_MATH_1	848	852	PF00917	0.607
DOC_WW_Pin1_4	1019	1024	PF00397	0.713
DOC_WW_Pin1_4	1076	1081	PF00397	0.777
DOC_WW_Pin1_4	794	799	PF00397	0.686
DOC_WW_Pin1_4	842	847	PF00397	0.539
DOC_WW_Pin1_4	900	905	PF00397	0.618
DOC_WW_Pin1_4	917	922	PF00397	0.661
DOC_WW_Pin1_4	950	955	PF00397	0.638
DOC_WW_Pin1_4	960	965	PF00397	0.650
DOC_WW_Pin1_4	967	972	PF00397	0.654
DOC_WW_Pin1_4	977	982	PF00397	0.637
DOC_WW_Pin1_4	995	1000	PF00397	0.739
LIG_14-3-3_CanoR_1	239	246	PF00244	0.541
LIG_14-3-3_CanoR_1	256	264	PF00244	0.404
LIG_14-3-3_CanoR_1	407	416	PF00244	0.572
LIG_14-3-3_CanoR_1	463	473	PF00244	0.406
LIG_14-3-3_CanoR_1	521	528	PF00244	0.587
LIG_14-3-3_CanoR_1	687	691	PF00244	0.550
LIG_14-3-3_CanoR_1	703	711	PF00244	0.653
LIG_Actin_WH2_2	412	430	PF00022	0.441
LIG_APCC_ABBA_1	902	907	PF00400	0.516
LIG_BRCT_BRCA1_1	652	656	PF00533	0.506
LIG_BRCT_BRCA1_2	652	658	PF00533	0.453
LIG_CtBP_PxDLS_1	927	931	PF00389	0.622
LIG_FHA_1	1008	1014	PF00498	0.615
LIG_FHA_1	1015	1021	PF00498	0.547
LIG_FHA_1	1033	1039	PF00498	0.675
LIG_FHA_1	245	251	PF00498	0.540
LIG_FHA_1	270	276	PF00498	0.478
LIG_FHA_1	49	55	PF00498	0.532
LIG_FHA_1	530	536	PF00498	0.484
LIG_FHA_1	664	670	PF00498	0.461
LIG_FHA_1	746	752	PF00498	0.505
LIG_FHA_1	901	907	PF00498	0.776
LIG_FHA_1	946	952	PF00498	0.669
LIG_FHA_1	996	1002	PF00498	0.682
LIG_FHA_2	220	226	PF00498	0.576
LIG_FHA_2	256	262	PF00498	0.556
LIG_FHA_2	393	399	PF00498	0.631
LIG_FHA_2	694	700	PF00498	0.596
LIG_FHA_2	704	710	PF00498	0.652
LIG_FHA_2	909	915	PF00498	0.600
LIG_Integrin_RGD_1	553	555	PF01839	0.391
LIG_LIR_Apic_2	1015	1021	PF02991	0.722
LIG_LIR_Gen_1	1055	1065	PF02991	0.562
LIG_LIR_Nem_3	1055	1060	PF02991	0.564
LIG_LIR_Nem_3	24	29	PF02991	0.714
LIG_LIR_Nem_3	696	700	PF02991	0.582
LIG_LIR_Nem_3	72	78	PF02991	0.426
LIG_MYND_1	1000	1004	PF01753	0.591
LIG_NRBOX	270	276	PF00104	0.490
LIG_Pex14_1	693	697	PF04695	0.532
LIG_PROFILIN_1	804	810	PF00235	0.562
LIG_PTAP_UEV_1	809	814	PF05743	0.577
LIG_Rb_pABgroove_1	311	319	PF01858	0.510
LIG_RPA_C_Fungi	541	553	PF08784	0.560
LIG_SH2_CRK	1018	1022	PF00017	0.674
LIG_SH2_CRK	1057	1061	PF00017	0.673
LIG_SH2_CRK	1087	1091	PF00017	0.748
LIG_SH2_NCK_1	1018	1022	PF00017	0.557
LIG_SH2_NCK_1	1057	1061	PF00017	0.561
LIG_SH2_NCK_1	1087	1091	PF00017	0.582
LIG_SH2_SRC	967	970	PF00017	0.647
LIG_SH2_STAP1	480	484	PF00017	0.501
LIG_SH2_STAP1	619	623	PF00017	0.522
LIG_SH3_1	1087	1093	PF00018	0.573
LIG_SH3_3	1020	1026	PF00018	0.629
LIG_SH3_3	1044	1050	PF00018	0.565
LIG_SH3_3	1057	1063	PF00018	0.509
LIG_SH3_3	1065	1071	PF00018	0.658
LIG_SH3_3	1087	1093	PF00018	0.655
LIG_SH3_3	788	794	PF00018	0.619
LIG_SH3_3	801	807	PF00018	0.642
LIG_SH3_3	810	816	PF00018	0.595
LIG_SH3_3	851	857	PF00018	0.684
LIG_SH3_3	867	873	PF00018	0.695
LIG_SH3_3	879	885	PF00018	0.611
LIG_SH3_3	946	952	PF00018	0.654
LIG_SH3_3	975	981	PF00018	0.779
LIG_SH3_3	991	997	PF00018	0.563
LIG_SUMO_SIM_par_1	1098	1104	PF11976	0.588
LIG_SUMO_SIM_par_1	926	931	PF11976	0.623
LIG_SUMO_SIM_par_1	946	953	PF11976	0.723
LIG_TRAF2_1	201	204	PF00917	0.551
LIG_TRAF2_1	493	496	PF00917	0.455
LIG_TRAF2_1	538	541	PF00917	0.537
LIG_WRC_WIRS_1	932	937	PF05994	0.658
LIG_WW_2	1092	1095	PF00397	0.559
MOD_CDK_SPK_2	977	982	PF00069	0.629
MOD_CK1_1	1014	1020	PF00069	0.678
MOD_CK1_1	1066	1072	PF00069	0.781
MOD_CK1_1	1076	1082	PF00069	0.582
MOD_CK1_1	1104	1110	PF00069	0.700
MOD_CK1_1	219	225	PF00069	0.630
MOD_CK1_1	238	244	PF00069	0.337
MOD_CK1_1	545	551	PF00069	0.449
MOD_CK1_1	651	657	PF00069	0.635
MOD_CK1_1	686	692	PF00069	0.508
MOD_CK1_1	704	710	PF00069	0.606
MOD_CK1_1	931	937	PF00069	0.598
MOD_CK1_1	959	965	PF00069	0.675
MOD_CK1_1	995	1001	PF00069	0.739
MOD_CK2_1	219	225	PF00069	0.485
MOD_CK2_1	255	261	PF00069	0.548
MOD_CK2_1	305	311	PF00069	0.485
MOD_CK2_1	392	398	PF00069	0.572
MOD_CK2_1	490	496	PF00069	0.500
MOD_CK2_1	693	699	PF00069	0.534
MOD_Cter_Amidation	937	940	PF01082	0.595
MOD_GlcNHglycan	1039	1042	PF01048	0.631
MOD_GlcNHglycan	1082	1085	PF01048	0.635
MOD_GlcNHglycan	1087	1090	PF01048	0.582
MOD_GlcNHglycan	1113	1116	PF01048	0.724
MOD_GlcNHglycan	179	182	PF01048	0.608
MOD_GlcNHglycan	199	202	PF01048	0.400
MOD_GlcNHglycan	29	32	PF01048	0.698
MOD_GlcNHglycan	307	310	PF01048	0.542
MOD_GlcNHglycan	35	38	PF01048	0.587
MOD_GlcNHglycan	449	452	PF01048	0.566
MOD_GlcNHglycan	492	495	PF01048	0.555
MOD_GlcNHglycan	522	525	PF01048	0.510
MOD_GlcNHglycan	547	550	PF01048	0.448
MOD_GlcNHglycan	571	576	PF01048	0.398
MOD_GlcNHglycan	649	653	PF01048	0.446
MOD_GlcNHglycan	703	706	PF01048	0.562
MOD_GlcNHglycan	751	754	PF01048	0.549
MOD_GlcNHglycan	788	791	PF01048	0.677
MOD_GlcNHglycan	801	804	PF01048	0.677
MOD_GlcNHglycan	810	813	PF01048	0.694
MOD_GlcNHglycan	846	849	PF01048	0.696
MOD_GlcNHglycan	850	853	PF01048	0.695
MOD_GlcNHglycan	874	877	PF01048	0.732
MOD_GlcNHglycan	940	943	PF01048	0.697
MOD_GlcNHglycan	984	987	PF01048	0.730
MOD_GSK3_1	1007	1014	PF00069	0.715
MOD_GSK3_1	1074	1081	PF00069	0.776
MOD_GSK3_1	1101	1108	PF00069	0.671
MOD_GSK3_1	173	180	PF00069	0.608
MOD_GSK3_1	285	292	PF00069	0.534
MOD_GSK3_1	443	450	PF00069	0.502
MOD_GSK3_1	464	471	PF00069	0.608
MOD_GSK3_1	541	548	PF00069	0.665
MOD_GSK3_1	701	708	PF00069	0.576
MOD_GSK3_1	745	752	PF00069	0.473
MOD_GSK3_1	821	828	PF00069	0.624
MOD_GSK3_1	830	837	PF00069	0.685
MOD_GSK3_1	840	847	PF00069	0.540
MOD_GSK3_1	926	933	PF00069	0.552
MOD_GSK3_1	956	963	PF00069	0.711
MOD_N-GLC_1	1011	1016	PF02516	0.593
MOD_N-GLC_1	464	469	PF02516	0.373
MOD_N-GLC_1	55	60	PF02516	0.689
MOD_N-GLC_1	586	591	PF02516	0.428
MOD_N-GLC_1	848	853	PF02516	0.709
MOD_NEK2_1	105	110	PF00069	0.483
MOD_NEK2_1	1105	1110	PF00069	0.693
MOD_NEK2_1	235	240	PF00069	0.530
MOD_NEK2_1	252	257	PF00069	0.495
MOD_NEK2_1	285	290	PF00069	0.504
MOD_NEK2_1	302	307	PF00069	0.421
MOD_NEK2_1	384	389	PF00069	0.685
MOD_NEK2_1	5	10	PF00069	0.549
MOD_NEK2_1	50	55	PF00069	0.601
MOD_NEK2_1	683	688	PF00069	0.581
MOD_NEK2_1	930	935	PF00069	0.704
MOD_NEK2_1	958	963	PF00069	0.701
MOD_PIKK_1	433	439	PF00454	0.522
MOD_PIKK_1	468	474	PF00454	0.510
MOD_PKA_2	238	244	PF00069	0.541
MOD_PKA_2	255	261	PF00069	0.400
MOD_PKA_2	5	11	PF00069	0.593
MOD_PKA_2	520	526	PF00069	0.567
MOD_PKA_2	545	551	PF00069	0.491
MOD_PKA_2	611	617	PF00069	0.499
MOD_PKA_2	663	669	PF00069	0.546
MOD_PKA_2	686	692	PF00069	0.505
MOD_PKA_2	749	755	PF00069	0.606
MOD_PKA_2	864	870	PF00069	0.770
MOD_PKA_2	88	94	PF00069	0.599
MOD_PKA_2	938	944	PF00069	0.656
MOD_Plk_1	105	111	PF00069	0.443
MOD_Plk_1	191	197	PF00069	0.493
MOD_Plk_1	376	382	PF00069	0.626
MOD_Plk_1	55	61	PF00069	0.623
MOD_Plk_1	586	592	PF00069	0.539
MOD_Plk_4	5	11	PF00069	0.614
MOD_ProDKin_1	1019	1025	PF00069	0.713
MOD_ProDKin_1	1076	1082	PF00069	0.777
MOD_ProDKin_1	794	800	PF00069	0.685
MOD_ProDKin_1	842	848	PF00069	0.538
MOD_ProDKin_1	900	906	PF00069	0.617
MOD_ProDKin_1	917	923	PF00069	0.658
MOD_ProDKin_1	950	956	PF00069	0.637
MOD_ProDKin_1	960	966	PF00069	0.650
MOD_ProDKin_1	967	973	PF00069	0.653
MOD_ProDKin_1	977	983	PF00069	0.638
MOD_ProDKin_1	995	1001	PF00069	0.743
MOD_SUMO_for_1	170	173	PF00179	0.512
MOD_SUMO_for_1	335	338	PF00179	0.504
MOD_SUMO_for_1	412	415	PF00179	0.597
MOD_SUMO_for_1	568	571	PF00179	0.488
MOD_SUMO_rev_2	130	138	PF00179	0.489
MOD_SUMO_rev_2	292	299	PF00179	0.427
MOD_SUMO_rev_2	318	323	PF00179	0.446
TRG_DiLeu_BaEn_1	106	111	PF01217	0.524
TRG_DiLeu_BaEn_1	360	365	PF01217	0.513
TRG_DiLeu_BaEn_4	208	214	PF01217	0.499
TRG_DiLeu_BaEn_4	482	488	PF01217	0.490
TRG_DiLeu_BaEn_4	674	680	PF01217	0.537
TRG_DiLeu_BaEn_4	734	740	PF01217	0.459
TRG_DiLeu_BaLyEn_6	122	127	PF01217	0.444
TRG_DiLeu_BaLyEn_6	997	1002	PF01217	0.633
TRG_DiLeu_LyEn_5	106	111	PF01217	0.397
TRG_ENDOCYTIC_2	1057	1060	PF00928	0.641
TRG_ENDOCYTIC_2	697	700	PF00928	0.555
TRG_ENDOCYTIC_2	74	77	PF00928	0.450
TRG_ER_diArg_1	101	104	PF00400	0.589
TRG_ER_diArg_1	115	118	PF00400	0.425
TRG_ER_diArg_1	148	150	PF00400	0.468
TRG_ER_diArg_1	157	159	PF00400	0.464
TRG_ER_diArg_1	341	343	PF00400	0.489
TRG_ER_diArg_1	421	423	PF00400	0.497
TRG_ER_diArg_1	462	464	PF00400	0.518
TRG_ER_diArg_1	560	563	PF00400	0.509
TRG_ER_diArg_1	599	601	PF00400	0.532
TRG_ER_diArg_1	64	66	PF00400	0.479
TRG_ER_diArg_1	679	681	PF00400	0.556
TRG_ER_diArg_1	726	728	PF00400	0.570
TRG_NES_CRM1_1	242	253	PF08389	0.501
TRG_NLS_Bipartite_1	521	537	PF00514	0.603
TRG_NLS_MonoExtN_4	486	493	PF00514	0.546
TRG_Pf-PMV_PEXEL_1	109	113	PF00026	0.474
TRG_Pf-PMV_PEXEL_1	125	130	PF00026	0.339
TRG_Pf-PMV_PEXEL_1	131	135	PF00026	0.419
TRG_Pf-PMV_PEXEL_1	159	164	PF00026	0.527
TRG_Pf-PMV_PEXEL_1	273	277	PF00026	0.544
TRG_Pf-PMV_PEXEL_1	341	345	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	369	374	PF00026	0.477
TRG_Pf-PMV_PEXEL_1	425	429	PF00026	0.515
TRG_Pf-PMV_PEXEL_1	439	443	PF00026	0.501
TRG_Pf-PMV_PEXEL_1	453	458	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	526	530	PF00026	0.508
TRG_Pf-PMV_PEXEL_1	578	583	PF00026	0.566
TRG_Pf-PMV_PEXEL_1	681	685	PF00026	0.468
TRG_Pf-PMV_PEXEL_1	727	731	PF00026	0.620
TRG_Pf-PMV_PEXEL_1	762	766	PF00026	0.557
TRG_Pf-PMV_PEXEL_1	779	784	PF00026	0.604

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2G2	Leptomonas seymouri	50%	97%
A0A0S4J512	Bodo saltans	25%	100%
A0A3R7M1Y7	Trypanosoma rangeli	29%	100%
A0A3S5H608	Leishmania donovani	91%	100%
A4H544	Leishmania braziliensis	72%	100%
C9ZUJ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
E9ALB3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	98%
V5B8B7	Trypanosoma cruzi	28%	100%