RNA binding protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein-like protein

Species:

Leishmania major

UniProt:

Q4QII7_LEIMA

TriTrypDb:

LmjF.07.1000 , LMJLV39_070017100 , LMJSD75_070017400

Length:

328

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4QII7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QII7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	162	166	PF00656	0.675
CLV_C14_Caspase3-7	178	182	PF00656	0.526
CLV_C14_Caspase3-7	202	206	PF00656	0.595
CLV_C14_Caspase3-7	232	236	PF00656	0.634
CLV_C14_Caspase3-7	244	248	PF00656	0.558
CLV_NRD_NRD_1	140	142	PF00675	0.652
CLV_PCSK_KEX2_1	140	142	PF00082	0.652
CLV_PCSK_PC1ET2_1	140	142	PF00082	0.652
CLV_PCSK_SKI1_1	322	326	PF00082	0.550
DOC_MAPK_gen_1	122	128	PF00069	0.578
DOC_PP2B_LxvP_1	18	21	PF13499	0.299
DOC_PP2B_LxvP_1	64	67	PF13499	0.299
DOC_USP7_MATH_1	109	113	PF00917	0.598
DOC_USP7_MATH_1	146	150	PF00917	0.657
DOC_USP7_MATH_1	324	328	PF00917	0.555
DOC_USP7_MATH_1	53	57	PF00917	0.358
DOC_USP7_MATH_1	82	86	PF00917	0.358
DOC_USP7_UBL2_3	123	127	PF12436	0.619
DOC_WW_Pin1_4	283	288	PF00397	0.628
DOC_WW_Pin1_4	293	298	PF00397	0.709
DOC_WW_Pin1_4	303	308	PF00397	0.593
DOC_WW_Pin1_4	8	13	PF00397	0.299
LIG_FHA_1	116	122	PF00498	0.517
LIG_FHA_1	145	151	PF00498	0.627
LIG_FHA_1	215	221	PF00498	0.576
LIG_FHA_1	40	46	PF00498	0.299
LIG_FHA_1	66	72	PF00498	0.289
LIG_FHA_2	132	138	PF00498	0.627
LIG_LIR_Gen_1	4	12	PF02991	0.312
LIG_LIR_Nem_3	4	8	PF02991	0.312
LIG_PTAP_UEV_1	221	226	PF05743	0.604
LIG_REV1ctd_RIR_1	78	87	PF16727	0.299
LIG_SH2_NCK_1	52	56	PF00017	0.358
LIG_SH2_STAT3	74	77	PF00017	0.334
LIG_SH2_STAT5	44	47	PF00017	0.299
LIG_SH3_3	123	129	PF00018	0.564
LIG_SH3_3	219	225	PF00018	0.605
LIG_SH3_3	28	34	PF00018	0.289
LIG_TRAF2_1	242	245	PF00917	0.733
LIG_TRAF2_1	253	256	PF00917	0.739
MOD_CDC14_SPxK_1	11	14	PF00782	0.289
MOD_CDK_SPxK_1	8	14	PF00069	0.289
MOD_CDK_SPxxK_3	283	290	PF00069	0.640
MOD_CDK_SPxxK_3	293	300	PF00069	0.551
MOD_CDK_SPxxK_3	303	310	PF00069	0.607
MOD_CK1_1	283	289	PF00069	0.682
MOD_CK1_1	29	35	PF00069	0.299
MOD_CK1_1	56	62	PF00069	0.358
MOD_CK2_1	131	137	PF00069	0.788
MOD_CK2_1	146	152	PF00069	0.577
MOD_CK2_1	177	183	PF00069	0.639
MOD_CK2_1	224	230	PF00069	0.614
MOD_CK2_1	239	245	PF00069	0.626
MOD_GlcNHglycan	111	114	PF01048	0.600
MOD_GlcNHglycan	165	168	PF01048	0.668
MOD_GlcNHglycan	169	173	PF01048	0.630
MOD_GlcNHglycan	282	285	PF01048	0.679
MOD_GlcNHglycan	291	294	PF01048	0.601
MOD_GlcNHglycan	301	304	PF01048	0.586
MOD_GlcNHglycan	311	314	PF01048	0.553
MOD_GlcNHglycan	45	48	PF01048	0.334
MOD_GlcNHglycan	84	87	PF01048	0.299
MOD_GSK3_1	111	118	PF00069	0.618
MOD_GSK3_1	131	138	PF00069	0.497
MOD_GSK3_1	144	151	PF00069	0.562
MOD_GSK3_1	173	180	PF00069	0.629
MOD_GSK3_1	220	227	PF00069	0.664
MOD_GSK3_1	289	296	PF00069	0.680
MOD_GSK3_1	299	306	PF00069	0.589
MOD_GSK3_1	34	41	PF00069	0.320
MOD_NEK2_1	26	31	PF00069	0.373
MOD_NEK2_2	39	44	PF00069	0.299
MOD_NEK2_2	84	89	PF00069	0.299
MOD_PIKK_1	56	62	PF00454	0.299
MOD_PKA_2	280	286	PF00069	0.682
MOD_PKA_2	289	295	PF00069	0.604
MOD_PKA_2	299	305	PF00069	0.513
MOD_PKA_2	309	315	PF00069	0.557
MOD_PKA_2	34	40	PF00069	0.334
MOD_PKB_1	320	328	PF00069	0.557
MOD_Plk_2-3	111	117	PF00069	0.588
MOD_Plk_2-3	131	137	PF00069	0.473
MOD_Plk_2-3	148	154	PF00069	0.549
MOD_Plk_2-3	173	179	PF00069	0.663
MOD_Plk_2-3	239	245	PF00069	0.653
MOD_Plk_4	26	32	PF00069	0.299
MOD_Plk_4	39	45	PF00069	0.299
MOD_Plk_4	59	65	PF00069	0.183
MOD_Plk_4	76	82	PF00069	0.212
MOD_ProDKin_1	283	289	PF00069	0.629
MOD_ProDKin_1	293	299	PF00069	0.709
MOD_ProDKin_1	303	309	PF00069	0.593
MOD_ProDKin_1	8	14	PF00069	0.299
MOD_SUMO_rev_2	205	215	PF00179	0.575
MOD_SUMO_rev_2	46	51	PF00179	0.299
MOD_SUMO_rev_2	9	18	PF00179	0.284
TRG_ER_diArg_1	320	323	PF00400	0.582
TRG_NLS_Bipartite_1	122	144	PF00514	0.600

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Y4	Leptomonas seymouri	53%	100%
A0A3S7WQ00	Leishmania donovani	82%	98%
A4H548	Leishmania braziliensis	68%	72%
A4HTC4	Leishmania infantum	80%	90%
E9ALB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	90%