ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair and recombination helicase protein PIF7, putative

Species:

Leishmania major

UniProt:

Q4QII5_LEIMA

TriTrypDb:

LmjF.07.1020 , LMJLV39_070017300 , LMJSD75_070017600

Length:

1222

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005657	replication fork	2	2
GO:0005739	mitochondrion	5	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	7
GO:0005737	cytoplasm	2	5

Expansion

Sequence features

Q4QII5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QII5

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006260	DNA replication	5	2
GO:0006281	DNA repair	5	7
GO:0006310	DNA recombination	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0006996	organelle organization	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	7
GO:0032200	telomere organization	6	7
GO:0032392	DNA geometric change	7	2
GO:0032508	DNA duplex unwinding	8	2
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051276	chromosome organization	5	7
GO:0051716	cellular response to stimulus	2	7
GO:0071103	DNA conformation change	6	2
GO:0071704	organic substance metabolic process	2	7
GO:0071840	cellular component organization or biogenesis	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0000287	magnesium ion binding	5	2
GO:0003678	DNA helicase activity	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016462	pyrophosphatase activity	5	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0016887	ATP hydrolysis activity	7	7
GO:0017076	purine nucleotide binding	4	7
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0043169	cation binding	3	2
GO:0046872	metal ion binding	4	2
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1046	1050	PF00656	0.632
CLV_C14_Caspase3-7	2	6	PF00656	0.633
CLV_C14_Caspase3-7	330	334	PF00656	0.388
CLV_C14_Caspase3-7	585	589	PF00656	0.528
CLV_C14_Caspase3-7	641	645	PF00656	0.329
CLV_C14_Caspase3-7	831	835	PF00656	0.532
CLV_C14_Caspase3-7	873	877	PF00656	0.633
CLV_C14_Caspase3-7	914	918	PF00656	0.696
CLV_C14_Caspase3-7	919	923	PF00656	0.695
CLV_NRD_NRD_1	1065	1067	PF00675	0.535
CLV_NRD_NRD_1	19	21	PF00675	0.650
CLV_NRD_NRD_1	211	213	PF00675	0.710
CLV_NRD_NRD_1	407	409	PF00675	0.312
CLV_NRD_NRD_1	475	477	PF00675	0.577
CLV_NRD_NRD_1	597	599	PF00675	0.405
CLV_NRD_NRD_1	784	786	PF00675	0.621
CLV_NRD_NRD_1	79	81	PF00675	0.621
CLV_NRD_NRD_1	874	876	PF00675	0.674
CLV_NRD_NRD_1	886	888	PF00675	0.610
CLV_NRD_NRD_1	945	947	PF00675	0.523
CLV_PCSK_FUR_1	405	409	PF00082	0.388
CLV_PCSK_FUR_1	782	786	PF00082	0.617
CLV_PCSK_KEX2_1	1065	1067	PF00082	0.559
CLV_PCSK_KEX2_1	19	21	PF00082	0.650
CLV_PCSK_KEX2_1	211	213	PF00082	0.710
CLV_PCSK_KEX2_1	407	409	PF00082	0.312
CLV_PCSK_KEX2_1	475	477	PF00082	0.577
CLV_PCSK_KEX2_1	500	502	PF00082	0.561
CLV_PCSK_KEX2_1	784	786	PF00082	0.621
CLV_PCSK_KEX2_1	79	81	PF00082	0.621
CLV_PCSK_KEX2_1	874	876	PF00082	0.773
CLV_PCSK_KEX2_1	885	887	PF00082	0.597
CLV_PCSK_KEX2_1	944	946	PF00082	0.531
CLV_PCSK_KEX2_1	958	960	PF00082	0.472
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.561
CLV_PCSK_PC1ET2_1	958	960	PF00082	0.451
CLV_PCSK_PC7_1	496	502	PF00082	0.654
CLV_PCSK_PC7_1	780	786	PF00082	0.604
CLV_PCSK_PC7_1	882	888	PF00082	0.585
CLV_PCSK_SKI1_1	1127	1131	PF00082	0.537
CLV_PCSK_SKI1_1	1161	1165	PF00082	0.514
CLV_PCSK_SKI1_1	1167	1171	PF00082	0.400
CLV_PCSK_SKI1_1	260	264	PF00082	0.381
CLV_PCSK_SKI1_1	271	275	PF00082	0.256
CLV_PCSK_SKI1_1	602	606	PF00082	0.436
CLV_PCSK_SKI1_1	690	694	PF00082	0.574
CLV_PCSK_SKI1_1	730	734	PF00082	0.441
CLV_PCSK_SKI1_1	79	83	PF00082	0.763
CLV_PCSK_SKI1_1	945	949	PF00082	0.486
CLV_PCSK_SKI1_1	959	963	PF00082	0.510
DEG_APCC_DBOX_1	426	434	PF00400	0.243
DEG_SCF_FBW7_1	947	952	PF00400	0.419
DEG_SPOP_SBC_1	295	299	PF00917	0.265
DEG_SPOP_SBC_1	837	841	PF00917	0.649
DOC_CKS1_1	1	6	PF01111	0.640
DOC_CYCLIN_RxL_1	769	779	PF00134	0.591
DOC_CYCLIN_RxL_1	77	87	PF00134	0.632
DOC_CYCLIN_yCln2_LP_2	1030	1036	PF00134	0.531
DOC_MAPK_gen_1	1089	1098	PF00069	0.486
DOC_MAPK_gen_1	178	185	PF00069	0.749
DOC_MAPK_gen_1	328	338	PF00069	0.498
DOC_MAPK_gen_1	347	357	PF00069	0.231
DOC_MAPK_gen_1	598	606	PF00069	0.427
DOC_MAPK_MEF2A_6	1116	1123	PF00069	0.403
DOC_MAPK_MEF2A_6	331	340	PF00069	0.340
DOC_MAPK_MEF2A_6	423	430	PF00069	0.312
DOC_MAPK_MEF2A_6	607	615	PF00069	0.477
DOC_MAPK_MEF2A_6	700	708	PF00069	0.355
DOC_PP1_RVXF_1	1148	1155	PF00149	0.495
DOC_PP1_RVXF_1	436	443	PF00149	0.396
DOC_PP1_RVXF_1	468	474	PF00149	0.626
DOC_PP1_RVXF_1	778	784	PF00149	0.503
DOC_PP2B_LxvP_1	398	401	PF13499	0.312
DOC_PP2B_LxvP_1	431	434	PF13499	0.234
DOC_PP4_FxxP_1	1069	1072	PF00568	0.510
DOC_PP4_FxxP_1	121	124	PF00568	0.635
DOC_SPAK_OSR1_1	1116	1120	PF12202	0.446
DOC_USP7_MATH_1	1022	1026	PF00917	0.495
DOC_USP7_MATH_1	140	144	PF00917	0.659
DOC_USP7_MATH_1	18	22	PF00917	0.639
DOC_USP7_MATH_1	240	244	PF00917	0.646
DOC_USP7_MATH_1	254	258	PF00917	0.278
DOC_USP7_MATH_1	295	299	PF00917	0.356
DOC_USP7_MATH_1	503	507	PF00917	0.607
DOC_USP7_MATH_1	510	514	PF00917	0.529
DOC_USP7_MATH_1	837	841	PF00917	0.649
DOC_USP7_MATH_1	905	909	PF00917	0.557
DOC_USP7_MATH_1	96	100	PF00917	0.649
DOC_USP7_UBL2_3	1130	1134	PF12436	0.553
DOC_USP7_UBL2_3	170	174	PF12436	0.564
DOC_USP7_UBL2_3	868	872	PF12436	0.644
DOC_WW_Pin1_4	1032	1037	PF00397	0.621
DOC_WW_Pin1_4	119	124	PF00397	0.614
DOC_WW_Pin1_4	136	141	PF00397	0.580
DOC_WW_Pin1_4	14	19	PF00397	0.633
DOC_WW_Pin1_4	408	413	PF00397	0.388
DOC_WW_Pin1_4	59	64	PF00397	0.609
DOC_WW_Pin1_4	801	806	PF00397	0.730
DOC_WW_Pin1_4	843	848	PF00397	0.658
DOC_WW_Pin1_4	945	950	PF00397	0.493
LIG_14-3-3_CanoR_1	1024	1033	PF00244	0.498
LIG_14-3-3_CanoR_1	1044	1052	PF00244	0.538
LIG_14-3-3_CanoR_1	1116	1120	PF00244	0.417
LIG_14-3-3_CanoR_1	1203	1208	PF00244	0.331
LIG_14-3-3_CanoR_1	19	24	PF00244	0.651
LIG_14-3-3_CanoR_1	211	215	PF00244	0.734
LIG_14-3-3_CanoR_1	253	263	PF00244	0.340
LIG_14-3-3_CanoR_1	344	350	PF00244	0.346
LIG_14-3-3_CanoR_1	436	441	PF00244	0.315
LIG_14-3-3_CanoR_1	475	483	PF00244	0.623
LIG_14-3-3_CanoR_1	567	576	PF00244	0.423
LIG_14-3-3_CanoR_1	744	751	PF00244	0.392
LIG_14-3-3_CanoR_1	760	768	PF00244	0.394
LIG_14-3-3_CanoR_1	782	792	PF00244	0.600
LIG_14-3-3_CanoR_1	845	854	PF00244	0.653
LIG_14-3-3_CanoR_1	90	95	PF00244	0.678
LIG_BIR_III_4	1144	1148	PF00653	0.562
LIG_BIR_III_4	5	9	PF00653	0.655
LIG_BRCT_BRCA1_1	296	300	PF00533	0.312
LIG_BRCT_BRCA1_1	393	397	PF00533	0.312
LIG_BRCT_BRCA1_1	410	414	PF00533	0.312
LIG_BRCT_BRCA1_1	431	435	PF00533	0.312
LIG_BRCT_BRCA1_1	438	442	PF00533	0.410
LIG_BRCT_BRCA1_1	855	859	PF00533	0.558
LIG_deltaCOP1_diTrp_1	1111	1117	PF00928	0.441
LIG_DLG_GKlike_1	1203	1210	PF00625	0.348
LIG_EVH1_1	72	76	PF00568	0.594
LIG_FHA_1	1102	1108	PF00498	0.510
LIG_FHA_1	1116	1122	PF00498	0.420
LIG_FHA_1	1186	1192	PF00498	0.344
LIG_FHA_1	153	159	PF00498	0.601
LIG_FHA_1	160	166	PF00498	0.576
LIG_FHA_1	30	36	PF00498	0.666
LIG_FHA_1	302	308	PF00498	0.342
LIG_FHA_1	349	355	PF00498	0.340
LIG_FHA_1	466	472	PF00498	0.501
LIG_FHA_1	590	596	PF00498	0.471
LIG_FHA_1	618	624	PF00498	0.441
LIG_FHA_1	63	69	PF00498	0.613
LIG_FHA_1	635	641	PF00498	0.524
LIG_FHA_1	677	683	PF00498	0.544
LIG_FHA_1	837	843	PF00498	0.562
LIG_FHA_1	935	941	PF00498	0.557
LIG_FHA_1	946	952	PF00498	0.516
LIG_FHA_2	1146	1152	PF00498	0.486
LIG_FHA_2	124	130	PF00498	0.617
LIG_FHA_2	203	209	PF00498	0.626
LIG_FHA_2	225	231	PF00498	0.600
LIG_FHA_2	37	43	PF00498	0.698
LIG_FHA_2	482	488	PF00498	0.537
LIG_FHA_2	527	533	PF00498	0.676
LIG_FHA_2	552	558	PF00498	0.429
LIG_FHA_2	620	626	PF00498	0.562
LIG_FHA_2	652	658	PF00498	0.535
LIG_FHA_2	721	727	PF00498	0.472
LIG_FHA_2	829	835	PF00498	0.541
LIG_LIR_Apic_2	1067	1072	PF02991	0.521
LIG_LIR_Apic_2	119	124	PF02991	0.636
LIG_LIR_Apic_2	89	95	PF02991	0.647
LIG_LIR_Gen_1	1111	1122	PF02991	0.427
LIG_LIR_Gen_1	366	375	PF02991	0.291
LIG_LIR_Gen_1	394	403	PF02991	0.312
LIG_LIR_Gen_1	546	556	PF02991	0.411
LIG_LIR_Gen_1	624	634	PF02991	0.405
LIG_LIR_Gen_1	657	667	PF02991	0.308
LIG_LIR_LC3C_4	679	684	PF02991	0.489
LIG_LIR_Nem_3	1111	1117	PF02991	0.498
LIG_LIR_Nem_3	1171	1175	PF02991	0.382
LIG_LIR_Nem_3	364	370	PF02991	0.312
LIG_LIR_Nem_3	384	389	PF02991	0.183
LIG_LIR_Nem_3	394	400	PF02991	0.312
LIG_LIR_Nem_3	419	424	PF02991	0.313
LIG_LIR_Nem_3	439	445	PF02991	0.343
LIG_LIR_Nem_3	542	548	PF02991	0.469
LIG_LIR_Nem_3	563	569	PF02991	0.443
LIG_LIR_Nem_3	624	629	PF02991	0.374
LIG_LIR_Nem_3	726	732	PF02991	0.400
LIG_LIR_Nem_3	738	742	PF02991	0.349
LIG_LIR_Nem_3	804	809	PF02991	0.560
LIG_PDZ_Class_2	1217	1222	PF00595	0.579
LIG_Pex14_2	729	733	PF04695	0.406
LIG_Pex14_2	996	1000	PF04695	0.441
LIG_SH2_CRK	1054	1058	PF00017	0.518
LIG_SH2_CRK	548	552	PF00017	0.382
LIG_SH2_CRK	566	570	PF00017	0.584
LIG_SH2_CRK	771	775	PF00017	0.417
LIG_SH2_CRK	806	810	PF00017	0.570
LIG_SH2_CRK	92	96	PF00017	0.659
LIG_SH2_NCK_1	92	96	PF00017	0.659
LIG_SH2_PTP2	739	742	PF00017	0.348
LIG_SH2_PTP2	808	811	PF00017	0.553
LIG_SH2_STAP1	1172	1176	PF00017	0.375
LIG_SH2_STAP1	1196	1200	PF00017	0.399
LIG_SH2_STAP1	161	165	PF00017	0.555
LIG_SH2_STAP1	261	265	PF00017	0.312
LIG_SH2_STAP1	710	714	PF00017	0.347
LIG_SH2_STAT3	565	568	PF00017	0.487
LIG_SH2_STAT5	1175	1178	PF00017	0.468
LIG_SH2_STAT5	1209	1212	PF00017	0.543
LIG_SH2_STAT5	161	164	PF00017	0.553
LIG_SH2_STAT5	373	376	PF00017	0.312
LIG_SH2_STAT5	548	551	PF00017	0.382
LIG_SH2_STAT5	633	636	PF00017	0.496
LIG_SH2_STAT5	739	742	PF00017	0.348
LIG_SH2_STAT5	808	811	PF00017	0.553
LIG_SH2_STAT5	92	95	PF00017	0.658
LIG_SH3_1	379	385	PF00018	0.312
LIG_SH3_3	1030	1036	PF00018	0.648
LIG_SH3_3	1095	1101	PF00018	0.486
LIG_SH3_3	1116	1122	PF00018	0.466
LIG_SH3_3	12	18	PF00018	0.654
LIG_SH3_3	139	145	PF00018	0.797
LIG_SH3_3	20	26	PF00018	0.582
LIG_SH3_3	236	242	PF00018	0.803
LIG_SH3_3	379	385	PF00018	0.312
LIG_SH3_3	680	686	PF00018	0.394
LIG_SH3_3	699	705	PF00018	0.359
LIG_SH3_3	70	76	PF00018	0.641
LIG_SH3_3	984	990	PF00018	0.521
LIG_Sin3_3	442	449	PF02671	0.296
LIG_SUMO_SIM_anti_2	1082	1088	PF11976	0.422
LIG_SUMO_SIM_anti_2	333	341	PF11976	0.340
LIG_SUMO_SIM_anti_2	457	464	PF11976	0.422
LIG_SUMO_SIM_anti_2	529	535	PF11976	0.642
LIG_SUMO_SIM_par_1	25	33	PF11976	0.634
LIG_SUMO_SIM_par_1	353	359	PF11976	0.388
LIG_TRAF2_1	793	796	PF00917	0.555
LIG_TRAF2_2	1036	1041	PF00917	0.632
LIG_TYR_ITIM	1052	1057	PF00017	0.518
LIG_TYR_ITSM	802	809	PF00017	0.544
LIG_UBA3_1	335	342	PF00899	0.340
LIG_WRC_WIRS_1	317	322	PF05994	0.312
LIG_WRC_WIRS_1	626	631	PF05994	0.395
LIG_WRC_WIRS_1	833	838	PF05994	0.628
LIG_WW_2	73	76	PF00397	0.582
MOD_CDC14_SPxK_1	17	20	PF00782	0.635
MOD_CDK_SPK_2	14	19	PF00069	0.675
MOD_CDK_SPxK_1	14	20	PF00069	0.642
MOD_CK1_1	1043	1049	PF00069	0.563
MOD_CK1_1	113	119	PF00069	0.575
MOD_CK1_1	187	193	PF00069	0.573
MOD_CK1_1	313	319	PF00069	0.290
MOD_CK1_1	334	340	PF00069	0.354
MOD_CK1_1	348	354	PF00069	0.244
MOD_CK1_1	464	470	PF00069	0.460
MOD_CK1_1	52	58	PF00069	0.635
MOD_CK1_1	589	595	PF00069	0.465
MOD_CK1_1	619	625	PF00069	0.377
MOD_CK1_1	62	68	PF00069	0.607
MOD_CK1_1	735	741	PF00069	0.411
MOD_CK1_1	743	749	PF00069	0.388
MOD_CK1_1	832	838	PF00069	0.658
MOD_CK1_1	84	90	PF00069	0.598
MOD_CK1_1	840	846	PF00069	0.621
MOD_CK1_1	921	927	PF00069	0.784
MOD_CK2_1	1022	1028	PF00069	0.491
MOD_CK2_1	1145	1151	PF00069	0.471
MOD_CK2_1	1176	1182	PF00069	0.443
MOD_CK2_1	123	129	PF00069	0.548
MOD_CK2_1	163	169	PF00069	0.702
MOD_CK2_1	202	208	PF00069	0.765
MOD_CK2_1	27	33	PF00069	0.623
MOD_CK2_1	358	364	PF00069	0.312
MOD_CK2_1	36	42	PF00069	0.593
MOD_CK2_1	526	532	PF00069	0.665
MOD_CK2_1	551	557	PF00069	0.427
MOD_CK2_1	83	89	PF00069	0.665
MOD_CK2_1	96	102	PF00069	0.567
MOD_GlcNHglycan	110	113	PF01048	0.539
MOD_GlcNHglycan	1213	1217	PF01048	0.619
MOD_GlcNHglycan	149	152	PF01048	0.643
MOD_GlcNHglycan	188	192	PF01048	0.574
MOD_GlcNHglycan	242	245	PF01048	0.584
MOD_GlcNHglycan	312	315	PF01048	0.312
MOD_GlcNHglycan	393	396	PF01048	0.312
MOD_GlcNHglycan	504	508	PF01048	0.599
MOD_GlcNHglycan	512	515	PF01048	0.530
MOD_GlcNHglycan	520	524	PF01048	0.573
MOD_GlcNHglycan	640	643	PF01048	0.443
MOD_GlcNHglycan	734	737	PF01048	0.446
MOD_GlcNHglycan	761	764	PF01048	0.350
MOD_GlcNHglycan	902	906	PF01048	0.680
MOD_GlcNHglycan	991	994	PF01048	0.498
MOD_GSK3_1	1022	1029	PF00069	0.525
MOD_GSK3_1	106	113	PF00069	0.535
MOD_GSK3_1	119	126	PF00069	0.613
MOD_GSK3_1	136	143	PF00069	0.593
MOD_GSK3_1	14	21	PF00069	0.658
MOD_GSK3_1	152	159	PF00069	0.584
MOD_GSK3_1	197	204	PF00069	0.667
MOD_GSK3_1	210	217	PF00069	0.600
MOD_GSK3_1	25	32	PF00069	0.611
MOD_GSK3_1	269	276	PF00069	0.388
MOD_GSK3_1	295	302	PF00069	0.274
MOD_GSK3_1	312	319	PF00069	0.422
MOD_GSK3_1	327	334	PF00069	0.312
MOD_GSK3_1	461	468	PF00069	0.420
MOD_GSK3_1	474	481	PF00069	0.577
MOD_GSK3_1	52	59	PF00069	0.634
MOD_GSK3_1	546	553	PF00069	0.378
MOD_GSK3_1	617	624	PF00069	0.386
MOD_GSK3_1	634	641	PF00069	0.430
MOD_GSK3_1	692	699	PF00069	0.577
MOD_GSK3_1	710	717	PF00069	0.394
MOD_GSK3_1	743	750	PF00069	0.507
MOD_GSK3_1	759	766	PF00069	0.345
MOD_GSK3_1	824	831	PF00069	0.655
MOD_GSK3_1	832	839	PF00069	0.600
MOD_GSK3_1	90	97	PF00069	0.711
MOD_GSK3_1	901	908	PF00069	0.598
MOD_GSK3_1	917	924	PF00069	0.707
MOD_GSK3_1	945	952	PF00069	0.528
MOD_N-GLC_1	310	315	PF02516	0.312
MOD_N-GLC_1	616	621	PF02516	0.403
MOD_N-GLC_1	934	939	PF02516	0.591
MOD_NEK2_1	1074	1079	PF00069	0.513
MOD_NEK2_1	108	113	PF00069	0.693
MOD_NEK2_1	1115	1120	PF00069	0.446
MOD_NEK2_1	1176	1181	PF00069	0.410
MOD_NEK2_1	27	32	PF00069	0.634
MOD_NEK2_1	286	291	PF00069	0.388
MOD_NEK2_1	310	315	PF00069	0.312
MOD_NEK2_1	521	526	PF00069	0.653
MOD_NEK2_1	54	59	PF00069	0.636
MOD_NEK2_1	551	556	PF00069	0.411
MOD_NEK2_1	634	639	PF00069	0.440
MOD_NEK2_1	720	725	PF00069	0.418
MOD_NEK2_1	82	87	PF00069	0.643
MOD_NEK2_1	836	841	PF00069	0.641
MOD_NEK2_1	934	939	PF00069	0.683
MOD_NEK2_1	950	955	PF00069	0.389
MOD_NEK2_2	1053	1058	PF00069	0.600
MOD_NEK2_2	1145	1150	PF00069	0.452
MOD_NEK2_2	710	715	PF00069	0.354
MOD_OFUCOSY	345	352	PF10250	0.340
MOD_PIKK_1	1028	1034	PF00454	0.679
MOD_PIKK_1	634	640	PF00454	0.459
MOD_PIKK_1	714	720	PF00454	0.444
MOD_PIKK_1	880	886	PF00454	0.664
MOD_PK_1	19	25	PF00069	0.652
MOD_PKA_1	19	25	PF00069	0.652
MOD_PKA_1	407	413	PF00069	0.388
MOD_PKA_2	1043	1049	PF00069	0.665
MOD_PKA_2	1115	1121	PF00069	0.416
MOD_PKA_2	159	165	PF00069	0.549
MOD_PKA_2	18	24	PF00069	0.643
MOD_PKA_2	210	216	PF00069	0.817
MOD_PKA_2	327	333	PF00069	0.388
MOD_PKA_2	407	413	PF00069	0.388
MOD_PKA_2	474	480	PF00069	0.604
MOD_PKA_2	526	532	PF00069	0.685
MOD_PKA_2	551	557	PF00069	0.408
MOD_PKA_2	651	657	PF00069	0.468
MOD_PKA_2	743	749	PF00069	0.390
MOD_PKA_2	759	765	PF00069	0.410
MOD_PKA_2	783	789	PF00069	0.595
MOD_PKA_2	824	830	PF00069	0.683
MOD_PKA_2	971	977	PF00069	0.412
MOD_PKB_1	1201	1209	PF00069	0.412
MOD_PKB_1	405	413	PF00069	0.388
MOD_Plk_1	358	364	PF00069	0.312
MOD_Plk_1	587	593	PF00069	0.529
MOD_Plk_1	934	940	PF00069	0.629
MOD_Plk_2-3	358	364	PF00069	0.312
MOD_Plk_4	1012	1018	PF00069	0.495
MOD_Plk_4	113	119	PF00069	0.667
MOD_Plk_4	1187	1193	PF00069	0.346
MOD_Plk_4	296	302	PF00069	0.312
MOD_Plk_4	316	322	PF00069	0.183
MOD_Plk_4	331	337	PF00069	0.358
MOD_Plk_4	358	364	PF00069	0.312
MOD_Plk_4	546	552	PF00069	0.402
MOD_Plk_4	651	657	PF00069	0.468
MOD_Plk_4	658	664	PF00069	0.364
MOD_Plk_4	735	741	PF00069	0.429
MOD_Plk_4	813	819	PF00069	0.521
MOD_ProDKin_1	1032	1038	PF00069	0.626
MOD_ProDKin_1	119	125	PF00069	0.616
MOD_ProDKin_1	136	142	PF00069	0.576
MOD_ProDKin_1	14	20	PF00069	0.635
MOD_ProDKin_1	408	414	PF00069	0.388
MOD_ProDKin_1	59	65	PF00069	0.613
MOD_ProDKin_1	801	807	PF00069	0.730
MOD_ProDKin_1	843	849	PF00069	0.657
MOD_ProDKin_1	945	951	PF00069	0.495
MOD_SUMO_for_1	173	176	PF00179	0.557
MOD_SUMO_for_1	499	502	PF00179	0.498
MOD_SUMO_for_1	854	857	PF00179	0.675
MOD_SUMO_rev_2	685	692	PF00179	0.477
MOD_SUMO_rev_2	726	732	PF00179	0.414
TRG_DiLeu_BaEn_1	813	818	PF01217	0.510
TRG_DiLeu_BaEn_2	468	474	PF01217	0.626
TRG_DiLeu_BaLyEn_6	1069	1074	PF01217	0.495
TRG_DiLeu_BaLyEn_6	1119	1124	PF01217	0.397
TRG_DiLeu_BaLyEn_6	702	707	PF01217	0.423
TRG_DiLeu_BaLyEn_6	946	951	PF01217	0.494
TRG_ENDOCYTIC_2	1054	1057	PF00928	0.565
TRG_ENDOCYTIC_2	182	185	PF00928	0.612
TRG_ENDOCYTIC_2	548	551	PF00928	0.382
TRG_ENDOCYTIC_2	566	569	PF00928	0.585
TRG_ENDOCYTIC_2	576	579	PF00928	0.429
TRG_ENDOCYTIC_2	739	742	PF00928	0.348
TRG_ENDOCYTIC_2	771	774	PF00928	0.450
TRG_ENDOCYTIC_2	806	809	PF00928	0.562
TRG_ER_diArg_1	1124	1127	PF00400	0.453
TRG_ER_diArg_1	1200	1203	PF00400	0.415
TRG_ER_diArg_1	178	181	PF00400	0.625
TRG_ER_diArg_1	18	20	PF00400	0.634
TRG_ER_diArg_1	378	381	PF00400	0.312
TRG_ER_diArg_1	435	438	PF00400	0.312
TRG_ER_diArg_1	474	476	PF00400	0.581
TRG_ER_diArg_1	780	783	PF00400	0.513
TRG_ER_diArg_1	79	81	PF00400	0.621
TRG_ER_diArg_1	885	887	PF00400	0.688
TRG_ER_diArg_1	943	946	PF00400	0.531
TRG_Pf-PMV_PEXEL_1	1167	1171	PF00026	0.386
TRG_Pf-PMV_PEXEL_1	163	167	PF00026	0.686
TRG_Pf-PMV_PEXEL_1	253	258	PF00026	0.340
TRG_Pf-PMV_PEXEL_1	353	358	PF00026	0.312
TRG_Pf-PMV_PEXEL_1	567	572	PF00026	0.399
TRG_Pf-PMV_PEXEL_1	680	685	PF00026	0.474

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3C2	Leptomonas seymouri	55%	98%
A0A3S7WQ25	Leishmania donovani	91%	100%
A4H550	Leishmania braziliensis	70%	92%
A4HTC6	Leishmania infantum	91%	100%
E9ALB9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%