Sel1 repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QII3_LEIMA

TriTrypDb:

LmjF.07.1040 , LMJLV39_070017800 , LMJSD75_070018100

Length:

324

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QII3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QII3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	166	170	PF00656	0.435
CLV_C14_Caspase3-7	93	97	PF00656	0.571
CLV_NRD_NRD_1	253	255	PF00675	0.194
CLV_NRD_NRD_1	85	87	PF00675	0.694
CLV_PCSK_KEX2_1	253	255	PF00082	0.194
CLV_PCSK_KEX2_1	297	299	PF00082	0.386
CLV_PCSK_KEX2_1	316	318	PF00082	0.385
CLV_PCSK_KEX2_1	85	87	PF00082	0.618
CLV_PCSK_PC1ET2_1	297	299	PF00082	0.388
CLV_PCSK_PC1ET2_1	316	318	PF00082	0.607
CLV_PCSK_SKI1_1	196	200	PF00082	0.272
CLV_PCSK_SKI1_1	269	273	PF00082	0.445
CLV_PCSK_SKI1_1	313	317	PF00082	0.486
DOC_CYCLIN_RxL_1	266	276	PF00134	0.453
DOC_CYCLIN_yCln2_LP_2	134	140	PF00134	0.403
DOC_CYCLIN_yCln2_LP_2	46	52	PF00134	0.414
DOC_MAPK_DCC_7	42	52	PF00069	0.308
DOC_PP2B_LxvP_1	56	59	PF13499	0.370
DOC_USP7_MATH_1	11	15	PF00917	0.660
DOC_USP7_MATH_1	179	183	PF00917	0.349
DOC_USP7_MATH_1	208	212	PF00917	0.285
DOC_USP7_MATH_1	229	233	PF00917	0.404
DOC_USP7_MATH_1	34	38	PF00917	0.523
DOC_WW_Pin1_4	133	138	PF00397	0.589
DOC_WW_Pin1_4	14	19	PF00397	0.704
LIG_14-3-3_CanoR_1	206	215	PF00244	0.349
LIG_14-3-3_CanoR_1	86	92	PF00244	0.607
LIG_Actin_WH2_2	191	208	PF00022	0.463
LIG_BRCT_BRCA1_1	34	38	PF00533	0.487
LIG_deltaCOP1_diTrp_1	244	251	PF00928	0.284
LIG_FHA_1	189	195	PF00498	0.349
LIG_FHA_1	51	57	PF00498	0.345
LIG_FHA_1	98	104	PF00498	0.372
LIG_FHA_2	197	203	PF00498	0.314
LIG_FHA_2	304	310	PF00498	0.594
LIG_FHA_2	91	97	PF00498	0.592
LIG_LIR_Gen_1	117	127	PF02991	0.368
LIG_LIR_Nem_3	117	122	PF02991	0.358
LIG_NRBOX	266	272	PF00104	0.323
LIG_PCNA_PIPBox_1	161	170	PF02747	0.366
LIG_PCNA_yPIPBox_3	61	75	PF02747	0.405
LIG_SH2_SRC	213	216	PF00017	0.326
LIG_SH2_STAT5	213	216	PF00017	0.442
LIG_SH3_3	171	177	PF00018	0.417
LIG_SH3_3	7	13	PF00018	0.509
LIG_SUMO_SIM_anti_2	129	136	PF11976	0.561
LIG_WRC_WIRS_1	164	169	PF05994	0.408
MOD_CDK_SPK_2	14	19	PF00069	0.580
MOD_CK1_1	14	20	PF00069	0.704
MOD_CK1_1	200	206	PF00069	0.349
MOD_CK1_1	280	286	PF00069	0.534
MOD_CK1_1	32	38	PF00069	0.509
MOD_CK1_1	90	96	PF00069	0.513
MOD_CK2_1	196	202	PF00069	0.314
MOD_CK2_1	303	309	PF00069	0.426
MOD_CK2_1	34	40	PF00069	0.375
MOD_GlcNHglycan	119	122	PF01048	0.433
MOD_GlcNHglycan	13	16	PF01048	0.683
MOD_GlcNHglycan	210	213	PF01048	0.357
MOD_GlcNHglycan	279	282	PF01048	0.538
MOD_GlcNHglycan	32	35	PF01048	0.483
MOD_GlcNHglycan	7	10	PF01048	0.703
MOD_GSK3_1	196	203	PF00069	0.272
MOD_GSK3_1	29	36	PF00069	0.636
MOD_N-GLC_1	5	10	PF02516	0.625
MOD_NEK2_1	29	34	PF00069	0.463
MOD_PIKK_1	260	266	PF00454	0.463
MOD_PKA_1	85	91	PF00069	0.618
MOD_PKA_2	85	91	PF00069	0.616
MOD_Plk_2-3	163	169	PF00069	0.434
MOD_Plk_4	163	169	PF00069	0.370
MOD_Plk_4	200	206	PF00069	0.339
MOD_Plk_4	34	40	PF00069	0.487
MOD_Plk_4	51	57	PF00069	0.457
MOD_ProDKin_1	133	139	PF00069	0.582
MOD_ProDKin_1	14	20	PF00069	0.702
TRG_DiLeu_BaEn_1	310	315	PF01217	0.375
TRG_DiLeu_BaEn_2	162	168	PF01217	0.360
TRG_ER_diArg_1	252	254	PF00400	0.194
TRG_Pf-PMV_PEXEL_1	69	73	PF00026	0.480

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBF0	Leptomonas seymouri	49%	71%
A0A1X0NPV5	Trypanosomatidae	37%	95%
A0A3R7RGL1	Trypanosoma rangeli	36%	100%
A0A3S7WQ08	Leishmania donovani	92%	100%
A4HTC9	Leishmania infantum	91%	100%
E9AI29	Leishmania braziliensis	81%	73%
E9ALC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5BYB8	Trypanosoma cruzi	36%	100%