Bacterial transferase hexapeptide repeat protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Bacterial transferase hexapeptide (six repeats), putative

Species:

Leishmania major

UniProt:

Q4QIF1_LEIMA

TriTrypDb:

LmjF.08.0180 , LMJLV39_080006800 , LMJSD75_080006800

Length:

294

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIF1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIF1

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0016740	transferase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	255	257	PF00675	0.593
CLV_NRD_NRD_1	265	267	PF00675	0.510
CLV_PCSK_KEX2_1	255	257	PF00082	0.492
CLV_PCSK_KEX2_1	265	267	PF00082	0.652
CLV_PCSK_KEX2_1	36	38	PF00082	0.500
CLV_PCSK_PC1ET2_1	36	38	PF00082	0.500
CLV_PCSK_PC7_1	261	267	PF00082	0.510
CLV_PCSK_SKI1_1	255	259	PF00082	0.510
CLV_PCSK_SKI1_1	3	7	PF00082	0.592
CLV_PCSK_SKI1_1	52	56	PF00082	0.388
CLV_PCSK_SKI1_1	94	98	PF00082	0.372
DEG_ODPH_VHL_1	64	76	PF01847	0.321
DOC_MAPK_HePTP_8	252	264	PF00069	0.477
DOC_MAPK_MEF2A_6	245	252	PF00069	0.487
DOC_MAPK_MEF2A_6	255	264	PF00069	0.445
DOC_MAPK_RevD_3	242	256	PF00069	0.477
DOC_PP4_FxxP_1	257	260	PF00568	0.487
DOC_PP4_FxxP_1	63	66	PF00568	0.318
DOC_USP7_MATH_1	142	146	PF00917	0.397
DOC_USP7_MATH_1	159	163	PF00917	0.397
DOC_USP7_MATH_1	189	193	PF00917	0.535
DOC_WW_Pin1_4	185	190	PF00397	0.418
LIG_14-3-3_CanoR_1	108	112	PF00244	0.299
LIG_14-3-3_CanoR_1	25	29	PF00244	0.346
LIG_14-3-3_CanoR_1	272	276	PF00244	0.540
LIG_14-3-3_CanoR_1	3	9	PF00244	0.487
LIG_CSL_BTD_1	282	285	PF09270	0.536
LIG_FHA_1	218	224	PF00498	0.377
LIG_LIR_Apic_2	136	142	PF02991	0.357
LIG_LIR_Apic_2	60	66	PF02991	0.347
LIG_LYPXL_yS_3	40	43	PF13949	0.522
LIG_Pex14_2	11	15	PF04695	0.431
LIG_Rb_LxCxE_1	128	145	PF01857	0.420
LIG_SH2_CRK	84	88	PF00017	0.333
LIG_SH2_PTP2	139	142	PF00017	0.387
LIG_SH2_STAT5	122	125	PF00017	0.286
LIG_SH2_STAT5	139	142	PF00017	0.291
LIG_SH2_STAT5	14	17	PF00017	0.431
LIG_SH3_1	279	285	PF00018	0.530
LIG_SH3_3	279	285	PF00018	0.530
LIG_TYR_ITIM	82	87	PF00017	0.327
MOD_CK1_1	24	30	PF00069	0.393
MOD_GlcNHglycan	161	164	PF01048	0.465
MOD_GlcNHglycan	286	289	PF01048	0.593
MOD_GlcNHglycan	94	97	PF01048	0.309
MOD_GSK3_1	185	192	PF00069	0.515
MOD_GSK3_1	284	291	PF00069	0.579
MOD_GSK3_1	90	97	PF00069	0.391
MOD_LATS_1	92	98	PF00433	0.365
MOD_N-GLC_1	277	282	PF02516	0.648
MOD_N-GLC_1	3	8	PF02516	0.574
MOD_NEK2_1	271	276	PF00069	0.580
MOD_NEK2_1	83	88	PF00069	0.322
MOD_PIKK_1	55	61	PF00454	0.328
MOD_PKA_2	107	113	PF00069	0.300
MOD_PKA_2	24	30	PF00069	0.393
MOD_PKA_2	271	277	PF00069	0.537
MOD_Plk_1	100	106	PF00069	0.412
MOD_Plk_1	3	9	PF00069	0.569
MOD_Plk_4	107	113	PF00069	0.321
MOD_Plk_4	118	124	PF00069	0.329
MOD_Plk_4	24	30	PF00069	0.487
MOD_Plk_4	83	89	PF00069	0.301
MOD_Plk_4	94	100	PF00069	0.296
MOD_ProDKin_1	185	191	PF00069	0.417
TRG_DiLeu_BaEn_2	252	258	PF01217	0.454
TRG_ENDOCYTIC_2	14	17	PF00928	0.410
TRG_ENDOCYTIC_2	40	43	PF00928	0.478
TRG_ENDOCYTIC_2	51	54	PF00928	0.307
TRG_ENDOCYTIC_2	84	87	PF00928	0.340
TRG_ER_diArg_1	255	257	PF00400	0.555
TRG_ER_diArg_1	264	266	PF00400	0.463

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0A3	Leptomonas seymouri	29%	96%
A0A0N1ICC0	Leptomonas seymouri	84%	100%
A0A0S4JVD5	Bodo saltans	27%	92%
A0A0S4KEG1	Bodo saltans	60%	83%
A0A1X0NNY9	Trypanosomatidae	61%	100%
A0A3S7WQ41	Leishmania donovani	98%	100%
A0A3S7WRH8	Leishmania donovani	29%	96%
A4H585	Leishmania braziliensis	92%	100%
A4H9V5	Leishmania braziliensis	28%	96%
A4HTG9	Leishmania infantum	98%	100%
A4HUR5	Leishmania infantum	29%	96%
B2V5B7	Clostridium botulinum (strain Alaska E43 / Type E3)	26%	100%
B9K867	Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)	26%	100%
C9ZPP8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	100%
D0A7P7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	97%
E9AM97	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9ANE9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	96%
Q03YE4	Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y)	26%	100%
Q4QH77	Leishmania major	26%	100%
Q54JC2	Dictyostelium discoideum	27%	100%
Q94AU7	Arabidopsis thaliana	28%	100%
Q9C6B3	Arabidopsis thaliana	29%	100%
Q9FWR5	Arabidopsis thaliana	28%	100%
V5BBY5	Trypanosoma cruzi	27%	97%
V5BCJ4	Trypanosoma cruzi	71%	100%