Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4QID3_LEIMA

TriTrypDb:

LmjF.08.0360 , LMJLV39_080008800 , LMJSD75_080008800

Length:

718

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QID3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QID3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	192	196	PF00656	0.486
CLV_C14_Caspase3-7	203	207	PF00656	0.508
CLV_C14_Caspase3-7	440	444	PF00656	0.564
CLV_C14_Caspase3-7	654	658	PF00656	0.515
CLV_NRD_NRD_1	200	202	PF00675	0.551
CLV_NRD_NRD_1	376	378	PF00675	0.432
CLV_NRD_NRD_1	383	385	PF00675	0.434
CLV_NRD_NRD_1	45	47	PF00675	0.603
CLV_NRD_NRD_1	55	57	PF00675	0.530
CLV_NRD_NRD_1	703	705	PF00675	0.414
CLV_PCSK_FUR_1	374	378	PF00082	0.354
CLV_PCSK_KEX2_1	200	202	PF00082	0.551
CLV_PCSK_KEX2_1	300	302	PF00082	0.353
CLV_PCSK_KEX2_1	376	378	PF00082	0.550
CLV_PCSK_KEX2_1	383	385	PF00082	0.500
CLV_PCSK_KEX2_1	45	47	PF00082	0.602
CLV_PCSK_KEX2_1	471	473	PF00082	0.624
CLV_PCSK_KEX2_1	55	57	PF00082	0.528
CLV_PCSK_PC1ET2_1	300	302	PF00082	0.353
CLV_PCSK_PC1ET2_1	471	473	PF00082	0.624
CLV_PCSK_SKI1_1	496	500	PF00082	0.598
DEG_Nend_UBRbox_1	1	4	PF02207	0.507
DEG_SPOP_SBC_1	497	501	PF00917	0.669
DEG_SPOP_SBC_1	595	599	PF00917	0.602
DOC_CDC14_PxL_1	104	112	PF14671	0.427
DOC_CKS1_1	126	131	PF01111	0.462
DOC_CYCLIN_yCln2_LP_2	282	285	PF00134	0.545
DOC_CYCLIN_yCln2_LP_2	58	64	PF00134	0.426
DOC_MAPK_gen_1	704	710	PF00069	0.373
DOC_MAPK_MEF2A_6	74	81	PF00069	0.435
DOC_MAPK_MEF2A_6	99	107	PF00069	0.455
DOC_PP2B_LxvP_1	282	285	PF13499	0.545
DOC_PP2B_LxvP_1	58	61	PF13499	0.409
DOC_PP2B_LxvP_1	592	595	PF13499	0.657
DOC_PP2B_LxvP_1	624	627	PF13499	0.613
DOC_PP2B_LxvP_1	67	70	PF13499	0.427
DOC_PP4_FxxP_1	36	39	PF00568	0.451
DOC_USP7_MATH_1	136	140	PF00917	0.515
DOC_USP7_MATH_1	213	217	PF00917	0.515
DOC_USP7_MATH_1	268	272	PF00917	0.610
DOC_USP7_MATH_1	323	327	PF00917	0.547
DOC_USP7_MATH_1	404	408	PF00917	0.555
DOC_USP7_MATH_1	450	454	PF00917	0.627
DOC_USP7_MATH_1	497	501	PF00917	0.675
DOC_WW_Pin1_4	125	130	PF00397	0.462
DOC_WW_Pin1_4	271	276	PF00397	0.643
DOC_WW_Pin1_4	345	350	PF00397	0.475
DOC_WW_Pin1_4	418	423	PF00397	0.595
DOC_WW_Pin1_4	479	484	PF00397	0.604
DOC_WW_Pin1_4	500	505	PF00397	0.635
DOC_WW_Pin1_4	507	512	PF00397	0.552
DOC_WW_Pin1_4	514	519	PF00397	0.537
DOC_WW_Pin1_4	553	558	PF00397	0.552
DOC_WW_Pin1_4	656	661	PF00397	0.613
LIG_14-3-3_CanoR_1	374	382	PF00244	0.401
LIG_14-3-3_CanoR_1	496	506	PF00244	0.624
LIG_14-3-3_CanoR_1	642	648	PF00244	0.499
LIG_Actin_WH2_2	84	101	PF00022	0.431
LIG_BIR_III_4	443	447	PF00653	0.591
LIG_EH1_1	176	184	PF00400	0.354
LIG_eIF4E_1	177	183	PF01652	0.382
LIG_EVH1_1	283	287	PF00568	0.603
LIG_FHA_1	126	132	PF00498	0.473
LIG_FHA_1	212	218	PF00498	0.642
LIG_FHA_1	292	298	PF00498	0.497
LIG_FHA_1	334	340	PF00498	0.510
LIG_FHA_1	479	485	PF00498	0.655
LIG_FHA_1	497	503	PF00498	0.475
LIG_FHA_1	554	560	PF00498	0.548
LIG_FHA_1	667	673	PF00498	0.541
LIG_FHA_2	649	655	PF00498	0.523
LIG_HP1_1	427	431	PF01393	0.616
LIG_Integrin_RGD_1	193	195	PF01839	0.489
LIG_Integrin_RGD_1	201	203	PF01839	0.523
LIG_Integrin_RGD_1	655	657	PF01839	0.535
LIG_LIR_Gen_1	165	175	PF02991	0.534
LIG_LIR_Nem_3	165	171	PF02991	0.687
LIG_LIR_Nem_3	82	87	PF02991	0.539
LIG_LYPXL_yS_3	84	87	PF13949	0.411
LIG_MYND_1	129	133	PF01753	0.461
LIG_MYND_1	16	20	PF01753	0.457
LIG_MYND_1	623	627	PF01753	0.582
LIG_Pex14_2	32	36	PF04695	0.458
LIG_RPA_C_Fungi	371	383	PF08784	0.399
LIG_SH2_STAP1	151	155	PF00017	0.492
LIG_SH2_STAT3	558	561	PF00017	0.600
LIG_SH2_STAT5	151	154	PF00017	0.530
LIG_SH2_STAT5	241	244	PF00017	0.424
LIG_SH2_STAT5	389	392	PF00017	0.428
LIG_SH2_STAT5	558	561	PF00017	0.538
LIG_SH3_3	10	16	PF00018	0.479
LIG_SH3_3	102	108	PF00018	0.536
LIG_SH3_3	123	129	PF00018	0.606
LIG_SH3_3	17	23	PF00018	0.444
LIG_SH3_3	214	220	PF00018	0.674
LIG_SH3_3	245	251	PF00018	0.504
LIG_SH3_3	253	259	PF00018	0.609
LIG_SH3_3	281	287	PF00018	0.649
LIG_SH3_3	421	427	PF00018	0.583
LIG_SH3_3	657	663	PF00018	0.543
LIG_SUMO_SIM_anti_2	338	344	PF11976	0.486
LIG_SUMO_SIM_anti_2	706	712	PF11976	0.374
LIG_SUMO_SIM_par_1	590	599	PF11976	0.627
LIG_TRAF2_1	314	317	PF00917	0.390
LIG_UBA3_1	515	520	PF00899	0.652
LIG_WRC_WIRS_1	168	173	PF05994	0.547
LIG_WW_2	284	287	PF00397	0.623
MOD_CDC14_SPxK_1	517	520	PF00782	0.593
MOD_CDK_SPxK_1	514	520	PF00069	0.588
MOD_CDK_SPxxK_3	418	425	PF00069	0.553
MOD_CK1_1	127	133	PF00069	0.484
MOD_CK1_1	143	149	PF00069	0.706
MOD_CK1_1	167	173	PF00069	0.499
MOD_CK1_1	215	221	PF00069	0.588
MOD_CK1_1	271	277	PF00069	0.587
MOD_CK1_1	291	297	PF00069	0.513
MOD_CK1_1	462	468	PF00069	0.584
MOD_CK1_1	500	506	PF00069	0.699
MOD_CK1_1	539	545	PF00069	0.607
MOD_CK1_1	551	557	PF00069	0.745
MOD_CK1_1	599	605	PF00069	0.620
MOD_CK1_1	659	665	PF00069	0.620
MOD_CK2_1	220	226	PF00069	0.536
MOD_CK2_1	311	317	PF00069	0.391
MOD_CK2_1	318	324	PF00069	0.454
MOD_CK2_1	598	604	PF00069	0.646
MOD_GlcNHglycan	138	141	PF01048	0.515
MOD_GlcNHglycan	153	156	PF01048	0.506
MOD_GlcNHglycan	222	225	PF01048	0.521
MOD_GlcNHglycan	264	267	PF01048	0.627
MOD_GlcNHglycan	269	273	PF01048	0.765
MOD_GlcNHglycan	27	30	PF01048	0.456
MOD_GlcNHglycan	290	293	PF01048	0.569
MOD_GlcNHglycan	294	297	PF01048	0.516
MOD_GlcNHglycan	313	316	PF01048	0.276
MOD_GlcNHglycan	330	333	PF01048	0.758
MOD_GlcNHglycan	355	358	PF01048	0.472
MOD_GlcNHglycan	377	380	PF01048	0.427
MOD_GlcNHglycan	459	464	PF01048	0.658
MOD_GlcNHglycan	533	536	PF01048	0.594
MOD_GlcNHglycan	566	569	PF01048	0.469
MOD_GlcNHglycan	598	601	PF01048	0.676
MOD_GlcNHglycan	606	609	PF01048	0.594
MOD_GSK3_1	136	143	PF00069	0.739
MOD_GSK3_1	145	152	PF00069	0.542
MOD_GSK3_1	163	170	PF00069	0.572
MOD_GSK3_1	2	9	PF00069	0.505
MOD_GSK3_1	209	216	PF00069	0.541
MOD_GSK3_1	246	253	PF00069	0.582
MOD_GSK3_1	264	271	PF00069	0.501
MOD_GSK3_1	274	281	PF00069	0.578
MOD_GSK3_1	288	295	PF00069	0.471
MOD_GSK3_1	323	330	PF00069	0.519
MOD_GSK3_1	404	411	PF00069	0.690
MOD_GSK3_1	414	421	PF00069	0.655
MOD_GSK3_1	496	503	PF00069	0.642
MOD_GSK3_1	527	534	PF00069	0.622
MOD_GSK3_1	536	543	PF00069	0.571
MOD_GSK3_1	560	567	PF00069	0.466
MOD_GSK3_1	590	597	PF00069	0.626
MOD_GSK3_1	599	606	PF00069	0.590
MOD_GSK3_1	655	662	PF00069	0.630
MOD_N-GLC_2	630	632	PF02516	0.482
MOD_NEK2_1	142	147	PF00069	0.651
MOD_NEK2_1	164	169	PF00069	0.501
MOD_NEK2_1	353	358	PF00069	0.441
MOD_NEK2_1	505	510	PF00069	0.578
MOD_NEK2_1	51	56	PF00069	0.506
MOD_NEK2_1	538	543	PF00069	0.641
MOD_NEK2_1	635	640	PF00069	0.491
MOD_NEK2_1	643	648	PF00069	0.478
MOD_OFUCOSY	632	639	PF10250	0.482
MOD_PIKK_1	146	152	PF00454	0.622
MOD_PIKK_1	404	410	PF00454	0.659
MOD_PK_1	704	710	PF00069	0.388
MOD_PKA_1	704	710	PF00069	0.388
MOD_PKA_2	328	334	PF00069	0.710
MOD_PKA_2	375	381	PF00069	0.417
MOD_PKA_2	604	610	PF00069	0.679
MOD_Plk_1	164	170	PF00069	0.553
MOD_Plk_1	551	557	PF00069	0.508
MOD_Plk_4	278	284	PF00069	0.547
MOD_Plk_4	335	341	PF00069	0.549
MOD_Plk_4	462	468	PF00069	0.563
MOD_Plk_4	672	678	PF00069	0.487
MOD_ProDKin_1	125	131	PF00069	0.463
MOD_ProDKin_1	271	277	PF00069	0.647
MOD_ProDKin_1	345	351	PF00069	0.470
MOD_ProDKin_1	418	424	PF00069	0.590
MOD_ProDKin_1	479	485	PF00069	0.602
MOD_ProDKin_1	500	506	PF00069	0.635
MOD_ProDKin_1	507	513	PF00069	0.552
MOD_ProDKin_1	514	520	PF00069	0.536
MOD_ProDKin_1	553	559	PF00069	0.543
MOD_ProDKin_1	656	662	PF00069	0.611
MOD_SUMO_rev_2	356	364	PF00179	0.398
MOD_SUMO_rev_2	464	473	PF00179	0.614
TRG_DiLeu_BaEn_1	178	183	PF01217	0.410
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.453
TRG_DiLeu_BaLyEn_6	217	222	PF01217	0.542
TRG_DiLeu_BaLyEn_6	620	625	PF01217	0.599
TRG_ENDOCYTIC_2	168	171	PF00928	0.615
TRG_ENDOCYTIC_2	184	187	PF00928	0.342
TRG_ENDOCYTIC_2	241	244	PF00928	0.424
TRG_ENDOCYTIC_2	84	87	PF00928	0.411
TRG_ER_diArg_1	1	4	PF00400	0.530
TRG_ER_diArg_1	374	377	PF00400	0.443
TRG_ER_diArg_1	382	384	PF00400	0.431
TRG_ER_diArg_1	44	46	PF00400	0.603
TRG_ER_diArg_1	472	475	PF00400	0.611
TRG_ER_diArg_1	640	643	PF00400	0.436
TRG_ER_diArg_1	694	697	PF00400	0.442
TRG_NES_CRM1_1	432	443	PF08389	0.623
TRG_NLS_MonoExtC_3	470	475	PF00514	0.615

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IML5	Leptomonas seymouri	41%	100%
A0A3S7WQ81	Leishmania donovani	88%	100%
A4H5A8	Leishmania braziliensis	68%	100%
A4HTI7	Leishmania infantum	88%	100%
E9AMB5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%