LeishMANIAdb
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POP1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
POP1 domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4QIB9_LEIMA
TriTrypDb:
LmjF.08.0500 , LMJLV39_080010200 * , LMJSD75_080010200
Length:
362

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4QIB9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4QIB9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 118 122 PF00656 0.701
CLV_NRD_NRD_1 157 159 PF00675 0.716
CLV_NRD_NRD_1 17 19 PF00675 0.707
CLV_NRD_NRD_1 285 287 PF00675 0.685
CLV_NRD_NRD_1 315 317 PF00675 0.656
CLV_NRD_NRD_1 335 337 PF00675 0.571
CLV_NRD_NRD_1 59 61 PF00675 0.679
CLV_PCSK_KEX2_1 157 159 PF00082 0.704
CLV_PCSK_KEX2_1 17 19 PF00082 0.681
CLV_PCSK_KEX2_1 229 231 PF00082 0.802
CLV_PCSK_KEX2_1 285 287 PF00082 0.685
CLV_PCSK_KEX2_1 314 316 PF00082 0.665
CLV_PCSK_KEX2_1 335 337 PF00082 0.571
CLV_PCSK_PC1ET2_1 229 231 PF00082 0.685
CLV_PCSK_PC7_1 311 317 PF00082 0.666
CLV_PCSK_SKI1_1 18 22 PF00082 0.669
CLV_PCSK_SKI1_1 279 283 PF00082 0.628
DEG_APCC_DBOX_1 313 321 PF00400 0.675
DEG_APCC_DBOX_1 89 97 PF00400 0.658
DEG_SPOP_SBC_1 45 49 PF00917 0.618
DOC_CYCLIN_yCln2_LP_2 111 117 PF00134 0.584
DOC_USP7_MATH_1 137 141 PF00917 0.588
DOC_USP7_MATH_1 156 160 PF00917 0.719
DOC_USP7_MATH_1 176 180 PF00917 0.561
DOC_USP7_MATH_1 344 348 PF00917 0.562
DOC_USP7_MATH_1 45 49 PF00917 0.618
DOC_USP7_MATH_1 65 69 PF00917 0.529
DOC_USP7_MATH_1 70 74 PF00917 0.638
DOC_WW_Pin1_4 110 115 PF00397 0.620
DOC_WW_Pin1_4 161 166 PF00397 0.636
DOC_WW_Pin1_4 174 179 PF00397 0.624
DOC_WW_Pin1_4 209 214 PF00397 0.848
DOC_WW_Pin1_4 259 264 PF00397 0.768
DOC_WW_Pin1_4 265 270 PF00397 0.631
DOC_WW_Pin1_4 27 32 PF00397 0.733
DOC_WW_Pin1_4 320 325 PF00397 0.620
DOC_WW_Pin1_4 68 73 PF00397 0.654
LIG_14-3-3_CanoR_1 157 165 PF00244 0.638
LIG_14-3-3_CanoR_1 335 342 PF00244 0.601
LIG_14-3-3_CanoR_1 351 357 PF00244 0.447
LIG_BIR_III_2 162 166 PF00653 0.607
LIG_deltaCOP1_diTrp_1 184 192 PF00928 0.537
LIG_deltaCOP1_diTrp_1 277 282 PF00928 0.622
LIG_eIF4E_1 102 108 PF01652 0.640
LIG_FHA_1 178 184 PF00498 0.685
LIG_FHA_1 262 268 PF00498 0.543
LIG_FHA_1 353 359 PF00498 0.552
LIG_FHA_2 325 331 PF00498 0.622
LIG_LIR_Nem_3 182 188 PF02991 0.666
LIG_LIR_Nem_3 190 195 PF02991 0.569
LIG_LIR_Nem_3 275 281 PF02991 0.618
LIG_NRBOX 106 112 PF00104 0.527
LIG_PDZ_Class_3 357 362 PF00595 0.604
LIG_Pex14_1 278 282 PF04695 0.577
LIG_REV1ctd_RIR_1 279 290 PF16727 0.596
LIG_SH2_NCK_1 102 106 PF00017 0.633
LIG_SH2_NCK_1 337 341 PF00017 0.548
LIG_SH2_STAP1 102 106 PF00017 0.488
LIG_SH2_STAP1 337 341 PF00017 0.663
LIG_SH2_STAT5 102 105 PF00017 0.633
LIG_SH2_STAT5 337 340 PF00017 0.599
LIG_SH3_2 16 21 PF14604 0.713
LIG_SH3_3 10 16 PF00018 0.703
LIG_SH3_3 133 139 PF00018 0.645
LIG_SH3_3 66 72 PF00018 0.597
LIG_TRAF2_1 12 15 PF00917 0.653
LIG_TRAF2_1 97 100 PF00917 0.628
MOD_CK1_1 164 170 PF00069 0.670
MOD_CK1_1 177 183 PF00069 0.576
MOD_CK1_1 261 267 PF00069 0.690
MOD_CK1_1 41 47 PF00069 0.681
MOD_CK1_1 68 74 PF00069 0.695
MOD_CK1_1 84 90 PF00069 0.491
MOD_CK2_1 184 190 PF00069 0.665
MOD_CK2_1 324 330 PF00069 0.636
MOD_Cter_Amidation 227 230 PF01082 0.802
MOD_GlcNHglycan 139 142 PF01048 0.609
MOD_GlcNHglycan 158 161 PF01048 0.695
MOD_GlcNHglycan 287 290 PF01048 0.647
MOD_GlcNHglycan 346 349 PF01048 0.694
MOD_GlcNHglycan 43 46 PF01048 0.622
MOD_GlcNHglycan 82 86 PF01048 0.726
MOD_GSK3_1 152 159 PF00069 0.605
MOD_GSK3_1 170 177 PF00069 0.721
MOD_GSK3_1 179 186 PF00069 0.602
MOD_GSK3_1 212 219 PF00069 0.735
MOD_GSK3_1 258 265 PF00069 0.685
MOD_GSK3_1 320 327 PF00069 0.655
MOD_GSK3_1 41 48 PF00069 0.638
MOD_GSK3_1 70 77 PF00069 0.665
MOD_GSK3_1 81 88 PF00069 0.608
MOD_NEK2_1 129 134 PF00069 0.684
MOD_NEK2_1 270 275 PF00069 0.552
MOD_NEK2_1 287 292 PF00069 0.551
MOD_PIKK_1 95 101 PF00454 0.633
MOD_PKA_1 285 291 PF00069 0.636
MOD_PKA_1 335 341 PF00069 0.556
MOD_PKA_2 156 162 PF00069 0.697
MOD_PKA_2 285 291 PF00069 0.636
MOD_PKA_2 335 341 PF00069 0.556
MOD_Plk_1 183 189 PF00069 0.573
MOD_Plk_2-3 184 190 PF00069 0.592
MOD_ProDKin_1 110 116 PF00069 0.623
MOD_ProDKin_1 161 167 PF00069 0.638
MOD_ProDKin_1 174 180 PF00069 0.623
MOD_ProDKin_1 209 215 PF00069 0.851
MOD_ProDKin_1 259 265 PF00069 0.763
MOD_ProDKin_1 27 33 PF00069 0.730
MOD_ProDKin_1 320 326 PF00069 0.613
MOD_ProDKin_1 68 74 PF00069 0.654
MOD_SUMO_rev_2 240 245 PF00179 0.622
TRG_DiLeu_BaLyEn_6 106 111 PF01217 0.666
TRG_ENDOCYTIC_2 188 191 PF00928 0.647
TRG_ER_diArg_1 16 18 PF00400 0.662
TRG_ER_diArg_1 285 287 PF00400 0.636
TRG_ER_diArg_1 314 316 PF00400 0.714
TRG_ER_diArg_1 334 336 PF00400 0.562
TRG_ER_diArg_1 57 60 PF00400 0.639
TRG_NLS_MonoExtN_4 57 64 PF00514 0.614

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S5H654 Leishmania donovani 81% 99%
A4H5B7 Leishmania braziliensis 50% 95%
A4HTJ8 Leishmania infantum 82% 100%
E9AMC9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS